JP2010516763A5 - - Google Patents
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- Publication number
- JP2010516763A5 JP2010516763A5 JP2009547231A JP2009547231A JP2010516763A5 JP 2010516763 A5 JP2010516763 A5 JP 2010516763A5 JP 2009547231 A JP2009547231 A JP 2009547231A JP 2009547231 A JP2009547231 A JP 2009547231A JP 2010516763 A5 JP2010516763 A5 JP 2010516763A5
- Authority
- JP
- Japan
- Prior art keywords
- infectious pathogen
- composition
- extracellular matrix
- matrix material
- interest
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000015181 infectious disease Diseases 0.000 claims description 25
- 244000052769 pathogen Species 0.000 claims description 24
- 230000002458 infectious effect Effects 0.000 claims description 23
- 230000001717 pathogenic effect Effects 0.000 claims description 21
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims description 16
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims description 16
- 210000002744 extracellular matrix Anatomy 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 15
- 239000000427 antigen Substances 0.000 claims description 13
- 102000036639 antigens Human genes 0.000 claims description 13
- 108091007433 antigens Proteins 0.000 claims description 13
- 238000002360 preparation method Methods 0.000 claims description 9
- 230000002163 immunogen Effects 0.000 claims description 7
- 231100000765 toxin Toxicity 0.000 claims description 7
- 229960005486 vaccine Drugs 0.000 claims description 7
- 239000002671 adjuvant Substances 0.000 claims description 5
- 206010043376 Tetanus Diseases 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 230000000770 proinflammatory effect Effects 0.000 claims description 3
- 241000894007 species Species 0.000 claims description 3
- 239000012678 infectious agent Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 239000011159 matrix material Substances 0.000 claims 14
- 239000012646 vaccine adjuvant Substances 0.000 claims 10
- 229940124931 vaccine adjuvant Drugs 0.000 claims 10
- 230000000968 intestinal effect Effects 0.000 claims 5
- 210000004876 tela submucosa Anatomy 0.000 claims 4
- 230000001681 protective effect Effects 0.000 claims 3
- 239000002775 capsule Substances 0.000 claims 2
- 230000005847 immunogenicity Effects 0.000 claims 2
- 241000193738 Bacillus anthracis Species 0.000 claims 1
- 101000867232 Escherichia coli Heat-stable enterotoxin II Proteins 0.000 claims 1
- 206010019799 Hepatitis viral Diseases 0.000 claims 1
- 208000004554 Leishmaniasis Diseases 0.000 claims 1
- 208000005374 Poisoning Diseases 0.000 claims 1
- 102000029797 Prion Human genes 0.000 claims 1
- 108091000054 Prion Proteins 0.000 claims 1
- 206010037742 Rabies Diseases 0.000 claims 1
- 208000035506 Ricin poisoning Diseases 0.000 claims 1
- 241000193998 Streptococcus pneumoniae Species 0.000 claims 1
- 206010013023 diphtheria Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 231100000655 enterotoxin Toxicity 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 201000004792 malaria Diseases 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 231100000572 poisoning Toxicity 0.000 claims 1
- 230000000607 poisoning effect Effects 0.000 claims 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims 1
- 229960002766 tetanus vaccines Drugs 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
- 201000001862 viral hepatitis Diseases 0.000 claims 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/699,448 US9308252B2 (en) | 2005-10-27 | 2007-01-30 | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| PCT/US2007/069727 WO2008094276A1 (en) | 2007-01-30 | 2007-05-25 | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010516763A JP2010516763A (ja) | 2010-05-20 |
| JP2010516763A5 true JP2010516763A5 (OSRAM) | 2012-11-22 |
Family
ID=39359947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009547231A Pending JP2010516763A (ja) | 2007-01-30 | 2007-05-25 | 感染性病原体又は毒素に関連する疾患のためのワクチンアジュバントとしての細胞外マトリックス物質 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9308252B2 (OSRAM) |
| EP (1) | EP2114444B1 (OSRAM) |
| JP (1) | JP2010516763A (OSRAM) |
| CN (1) | CN101730541B (OSRAM) |
| AU (1) | AU2007345673A1 (OSRAM) |
| WO (2) | WO2008094276A1 (OSRAM) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8257715B1 (en) | 2004-08-26 | 2012-09-04 | University Of Notre Dame | Tissue vaccines and uses thereof |
| US8778360B2 (en) * | 2005-10-27 | 2014-07-15 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US8802113B2 (en) * | 2005-10-27 | 2014-08-12 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US9308252B2 (en) | 2005-10-27 | 2016-04-12 | Cook Biotech, Inc. | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
| US8652782B2 (en) | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
| US8080645B2 (en) * | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
| US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
| US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
| EP2772267B1 (en) | 2007-08-27 | 2016-04-27 | Longhorn Vaccines and Diagnostics, LLC | Immunogenic compositions and methods |
| US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| WO2009085355A2 (en) | 2007-10-01 | 2009-07-09 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection and transport system and methods of use |
| US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
| US9283266B2 (en) * | 2008-02-28 | 2016-03-15 | University Of Notre Dame | Metastasis inhibition preparations and methods |
| KR101881596B1 (ko) | 2008-12-02 | 2018-07-24 | 웨이브 라이프 사이언시스 재팬 인코포레이티드 | 인 원자 변형된 핵산의 합성 방법 |
| WO2010078478A1 (en) | 2008-12-31 | 2010-07-08 | Cook Biotech Incorporated | Tissue adjuvants and medical products including the same |
| RU2612521C2 (ru) | 2009-07-06 | 2017-03-09 | Онтории, Инк. | Новые пролекарства нуклеиновых кислот и способы их применения |
| US8846059B2 (en) | 2009-12-08 | 2014-09-30 | University Of Notre Dame | Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer |
| US20110150934A1 (en) * | 2009-12-18 | 2011-06-23 | University Of Notre Dame | Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer |
| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| BR112014001244A2 (pt) | 2011-07-19 | 2017-02-21 | Wave Life Sciences Pte Ltd | métodos para a síntese de ácidos nucléicos funcionalizados |
| CA2863083C (en) | 2012-01-26 | 2023-09-19 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| ES2862073T3 (es) | 2012-07-13 | 2021-10-06 | Wave Life Sciences Ltd | Grupo auxiliar asimétrico |
| CN112007045A (zh) | 2012-07-13 | 2020-12-01 | 波涛生命科学有限公司 | 手性控制 |
| BR112015000723A2 (pt) * | 2012-07-13 | 2017-06-27 | Shin Nippon Biomedical Laboratories Ltd | adjuvante de ácido nucléico quiral |
| CN103110943B (zh) * | 2013-03-11 | 2014-11-26 | 浙江普康生物技术股份有限公司 | 一种可替代氢氧化铝的新型疫苗佐剂 |
| EP3095460A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| US10144933B2 (en) | 2014-01-15 | 2018-12-04 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator |
| EP3095459A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
| CN113278617A (zh) | 2014-01-16 | 2021-08-20 | 波涛生命科学有限公司 | 手性设计 |
| WO2016183292A1 (en) | 2015-05-14 | 2016-11-17 | Longhorn Vaccines And Diagnostics, Llc | Rapid methods for the extraction of nucleic acids from biological samples |
| CN106860861B (zh) * | 2017-03-03 | 2020-11-03 | 北京博辉瑞进生物科技有限公司 | 一种免疫增强组合物、制备方法及其应用 |
| US12485166B2 (en) | 2020-02-06 | 2025-12-02 | Longhorn Vaccines And Diagnostics, Llc | Vaccines for the treatment and prevention of zoonotic infections |
| AU2021260940A1 (en) * | 2020-04-22 | 2022-12-15 | Fettech, Llc | Compositions comprising extracellular material with antiviral activity and uses thereof |
| KR20230091978A (ko) | 2020-10-20 | 2023-06-23 | 롱혼 백신즈 앤드 다이어그나스틱스, 엘엘씨 | 면역원성 항원 |
| US20250375512A1 (en) * | 2022-06-24 | 2025-12-11 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Use of matrix bound vesicles (mbv) as vaccine adjuvants |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2172903A (en) | 1937-09-24 | 1939-09-12 | Paul M Charping | Electric lighting system |
| US3346401A (en) | 1963-12-12 | 1967-10-10 | Council Scient Ind Res | Processing of raw intestines |
| AT261800B (de) | 1966-08-22 | 1968-05-10 | Braun Internat Gmbh B | Verfahren zur Herstellung von röhrenförmigen, glatten bzw. mit einem Gewinde versehenen Gewebe-Blutgefäß-Prothesen |
| US3810473A (en) | 1972-12-04 | 1974-05-14 | Avicon Inc | Liquid-laid, non-woven, fibrous collagen derived surgical web having hemostatic and wound sealing properties |
| US4578067A (en) | 1982-04-12 | 1986-03-25 | Alcon (Puerto Rico) Inc. | Hemostatic-adhesive, collagen dressing for severed biological surfaces |
| US4502159A (en) | 1982-08-12 | 1985-03-05 | Shiley Incorporated | Tubular prostheses prepared from pericardial tissue |
| EP0331786B1 (de) | 1988-03-11 | 1994-08-03 | CHEMOKOL G.b.R. Ing.-Büro für Kollagenprodukte | Verfahren zur Herstellung von Kollagenmembranen für Hämostase, Wundbehandlung und Implantate |
| US4956178A (en) | 1988-07-11 | 1990-09-11 | Purdue Research Foundation | Tissue graft composition |
| US4902508A (en) | 1988-07-11 | 1990-02-20 | Purdue Research Foundation | Tissue graft composition |
| US5837269A (en) | 1989-09-25 | 1998-11-17 | University Of Utah Research Foundation | Vaccine compositions and method for enhancing an immune response |
| US5336616A (en) | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
| US6120991A (en) * | 1990-10-30 | 2000-09-19 | Fred Hutchinson Cancer Research Center | Epiligrin, an epithelial ligand for integrins |
| US5281422A (en) | 1991-09-24 | 1994-01-25 | Purdue Research Foundation | Graft for promoting autogenous tissue growth |
| US5507810A (en) | 1991-10-07 | 1996-04-16 | Osteotech, Inc. | Processing of fibrous connective tissue |
| US5437287A (en) | 1992-08-17 | 1995-08-01 | Carbomedics, Inc. | Sterilization of tissue implants using iodine |
| US5352463A (en) | 1992-11-13 | 1994-10-04 | Badylak Steven F | Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor |
| US5275826A (en) | 1992-11-13 | 1994-01-04 | Purdue Research Foundation | Fluidized intestinal submucosa and its use as an injectable tissue graft |
| US5480424A (en) | 1993-11-01 | 1996-01-02 | Cox; James L. | Heart valve replacement using flexible tubes |
| US5460962A (en) | 1994-01-04 | 1995-10-24 | Organogenesis Inc. | Peracetic acid sterilization of collagen or collagenous tissue |
| US6156305A (en) | 1994-07-08 | 2000-12-05 | Baxter International Inc. | Implanted tumor cells for the prevention and treatment of cancer |
| US6218166B1 (en) | 1994-12-09 | 2001-04-17 | John Wayne Cancer Institute | Adjuvant incorporation into antigen carrying cells: compositions and methods |
| US5695998A (en) | 1995-02-10 | 1997-12-09 | Purdue Research Foundation | Submucosa as a growth substrate for islet cells |
| US7361332B2 (en) | 1995-03-17 | 2008-04-22 | The Regents Of The University Of California | Treating tumors using implants comprising combinations of allogeneic cells |
| US5554389A (en) | 1995-04-07 | 1996-09-10 | Purdue Research Foundation | Urinary bladder submucosa derived tissue graft |
| AU692094B2 (en) * | 1995-04-07 | 1998-05-28 | Methodist Health Group, Inc. | Tissue graft and method for urinary bladder reconstruction |
| US5733337A (en) | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
| US6406689B1 (en) | 1995-10-03 | 2002-06-18 | Frank W. Falkenberg | Compositions and methods for treatment of tumors and metastatic diseases |
| CA2250880C (en) | 1996-04-03 | 2008-01-15 | The Rogosin Institute | Implantable agarose-collagen beads containing cells which produce a diffusible biological product, and uses thereof |
| US6277368B1 (en) | 1996-07-25 | 2001-08-21 | The Regents Of The University Of California | Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine |
| DK0925077T3 (da) | 1996-08-23 | 2003-12-08 | Cook Biotech Inc | Fremgangsmåde til opnåelse af en oprenset collagen-baseret matrice fra submucosavæv |
| DE69718029T2 (de) | 1996-10-11 | 2003-10-16 | The Regents Of The University Of California, Oakland | Krebs immuntherapie unter verwendung von tumorzellen kombiniert mit lymphozytmischungen |
| US5782914A (en) | 1996-11-29 | 1998-07-21 | Bio-Vascular, Inc. | Method for preparing heterogeneous tissue grafts |
| PT981369E (pt) | 1997-05-12 | 2005-03-31 | Aphton Corp | Composicoes imunogenicas para o receptor de cck-b/gastrina e metodos para o tratamento de tumores |
| WO1999043786A2 (en) | 1998-02-27 | 1999-09-02 | Purdue Research Foundation | Submucosa gel compositions |
| DE19916085A1 (de) * | 1998-10-28 | 2000-05-04 | Sonntag Hans Guenther | Verfahren zur Herstellung eines antiviralen Mittels |
| GB9827103D0 (en) | 1998-12-10 | 1999-02-03 | Onyvax Ltd | New cancer treatments |
| JP2000264900A (ja) | 1999-03-16 | 2000-09-26 | Hisamitsu Pharmaceut Co Inc | 新規生理活性ペプチド |
| ATE341338T1 (de) | 1999-03-16 | 2006-10-15 | Univ Jefferson | Hapten modifizierte tumorzellen und verfahren zur herstellung und deren verwendung |
| US6105775A (en) * | 1999-04-20 | 2000-08-22 | Pakon, Inc. | Sleeving system for photographic film negatives |
| WO2000064446A1 (en) | 1999-04-26 | 2000-11-02 | Emory University | Noscapine derivatives as adjuvant compositions and methods of use thereof |
| US7015205B1 (en) | 1999-10-18 | 2006-03-21 | St. Vincent's Hospital And Medical Center Of New York | Melanoma vaccine and methods of making and using same |
| IT1318663B1 (it) | 2000-08-02 | 2003-08-27 | Mediolanum Farmaceutici Srl | Membrane di collagene a due facce di cui una organizzata a livellomacromolecolare. |
| WO2003002165A1 (en) * | 2001-06-28 | 2003-01-09 | Cook Biotech Incorporated | Graft prosthesis devices containing renal capsule collagen |
| AU2002324775A1 (en) * | 2001-08-23 | 2003-03-10 | Sciperio, Inc. | Architecture tool and methods of use |
| US20060078540A1 (en) | 2002-03-18 | 2006-04-13 | Warren William L | Dendritic cell nodes |
| FR2842822B1 (fr) | 2002-07-26 | 2004-10-01 | Roussy Inst Gustave | Procede de preparation d'une matrice extracellulaire et son utilisation pour la culture de cellules tumorales |
| WO2004017866A1 (en) | 2002-08-20 | 2004-03-04 | Cook Incorporated | Stent graft with improved proximal end |
| US7550004B2 (en) | 2002-08-20 | 2009-06-23 | Cook Biotech Incorporated | Endoluminal device with extracellular matrix material and methods |
| WO2005023321A2 (en) * | 2003-09-04 | 2005-03-17 | Cook Biotech Incorporated | Extracellular matrix composite materials, and manufacture and use thereof |
| US8257715B1 (en) | 2004-08-26 | 2012-09-04 | University Of Notre Dame | Tissue vaccines and uses thereof |
| EP1887980B1 (en) | 2005-05-17 | 2012-09-05 | Cook Medical Technologies LLC | Frameless valve prosthesis and system for its deployment |
| AU2006292203A1 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| US8778360B2 (en) | 2005-10-27 | 2014-07-15 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US9308252B2 (en) | 2005-10-27 | 2016-04-12 | Cook Biotech, Inc. | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| US8802113B2 (en) | 2005-10-27 | 2014-08-12 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US7545569B2 (en) * | 2006-01-13 | 2009-06-09 | Avery Dennison Corporation | Optical apparatus with flipped compound prism structures |
| CA2627364A1 (en) | 2007-01-30 | 2008-07-30 | University Of Notre Dame Du Lac | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| US9283266B2 (en) | 2008-02-28 | 2016-03-15 | University Of Notre Dame | Metastasis inhibition preparations and methods |
| US8846059B2 (en) | 2009-12-08 | 2014-09-30 | University Of Notre Dame | Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer |
| US20110150934A1 (en) | 2009-12-18 | 2011-06-23 | University Of Notre Dame | Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer |
-
2007
- 2007-01-30 US US11/699,448 patent/US9308252B2/en active Active
- 2007-05-25 JP JP2009547231A patent/JP2010516763A/ja active Pending
- 2007-05-25 CN CN200780052437.8A patent/CN101730541B/zh not_active Expired - Fee Related
- 2007-05-25 EP EP07797770.0A patent/EP2114444B1/en active Active
- 2007-05-25 AU AU2007345673A patent/AU2007345673A1/en not_active Abandoned
- 2007-05-25 WO PCT/US2007/069727 patent/WO2008094276A1/en not_active Ceased
-
2008
- 2008-01-24 WO PCT/US2008/051877 patent/WO2008112344A2/en not_active Ceased
-
2009
- 2009-10-13 US US12/578,359 patent/US20100136050A1/en not_active Abandoned
-
2010
- 2010-08-26 US US12/868,908 patent/US9220770B2/en active Active
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