JP2010514722A5 - - Google Patents
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- Publication number
- JP2010514722A5 JP2010514722A5 JP2009543400A JP2009543400A JP2010514722A5 JP 2010514722 A5 JP2010514722 A5 JP 2010514722A5 JP 2009543400 A JP2009543400 A JP 2009543400A JP 2009543400 A JP2009543400 A JP 2009543400A JP 2010514722 A5 JP2010514722 A5 JP 2010514722A5
- Authority
- JP
- Japan
- Prior art keywords
- cd95l
- soluble
- cd95r
- incorporated
- molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101000611023 Homo sapiens Tumor necrosis factor receptor superfamily member 6 Proteins 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 102000015212 Fas Ligand Protein Human genes 0.000 description 1
- 108010039471 Fas Ligand Protein Proteins 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87736706P | 2006-12-28 | 2006-12-28 | |
| US60/877,367 | 2006-12-28 | ||
| PCT/EP2007/011461 WO2008080623A2 (en) | 2006-12-28 | 2007-12-28 | Neutralization of cd95 activity blocks invasion of glioblastoma cells in vivo |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014116401A Division JP5893078B2 (ja) | 2006-12-28 | 2014-06-05 | インビボでの神経膠芽腫細胞の浸潤を阻害するｃｄ９５活性の中和 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010514722A JP2010514722A (ja) | 2010-05-06 |
| JP2010514722A5 true JP2010514722A5 (OSRAM) | 2013-03-28 |
| JP5558828B2 JP5558828B2 (ja) | 2014-07-23 |
Family
ID=39400900
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009543400A Expired - Fee Related JP5558828B2 (ja) | 2006-12-28 | 2007-12-28 | インビボでの神経膠芽腫細胞の浸潤を阻害するｃｄ９５活性の中和 |
| JP2014116401A Expired - Fee Related JP5893078B2 (ja) | 2006-12-28 | 2014-06-05 | インビボでの神経膠芽腫細胞の浸潤を阻害するｃｄ９５活性の中和 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014116401A Expired - Fee Related JP5893078B2 (ja) | 2006-12-28 | 2014-06-05 | インビボでの神経膠芽腫細胞の浸潤を阻害するｃｄ９５活性の中和 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9309320B2 (OSRAM) |
| EP (2) | EP2428252B1 (OSRAM) |
| JP (2) | JP5558828B2 (OSRAM) |
| AU (1) | AU2007341631B9 (OSRAM) |
| CA (1) | CA2673868C (OSRAM) |
| CY (1) | CY1116006T1 (OSRAM) |
| DK (2) | DK2101877T3 (OSRAM) |
| ES (2) | ES2523992T3 (OSRAM) |
| PL (2) | PL2101877T3 (OSRAM) |
| PT (2) | PT2428252E (OSRAM) |
| SI (1) | SI2428252T1 (OSRAM) |
| WO (1) | WO2008080623A2 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3072903B1 (en) | 2007-07-10 | 2017-10-25 | Apogenix AG | Tnf superfamily collectin fusion proteins |
| JP5665739B2 (ja) * | 2008-07-14 | 2015-02-04 | ドイチェス クレープスフォルシュングスツェントルムＤｅｕｔｓｃｈｅｓ Ｋｒｅｂｓｆｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ | 炎症性疾患を治療するためのｃｄ９５インヒビターの使用 |
| JP5844158B2 (ja) | 2009-01-09 | 2016-01-13 | アポゲニクス ゲゼルシャフト ミット ベシュレンクテル ハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ | 三量体形成融合タンパク質 |
| JP5754740B2 (ja) * | 2009-07-21 | 2015-07-29 | クイーン メアリー アンド ウェストフィールド カレッジＱｕｅｅｎ Ｍａｒｙ ａｎｄ Ｗｅｓｔｆｉｅｌｄ Ｃｏｌｌｅｇｅ | 細胞内薬物送達のためのｆａｓ（アポ−１，ｃｄ９５）標的化プラットフォーム |
| EP2322927A1 (en) * | 2009-11-16 | 2011-05-18 | Deutsches Krebsforschungszentrum | Compounds inhibiting CD95 signaling for the treatment of pancreatic cancer |
| CA2878992C (en) * | 2012-07-18 | 2020-09-22 | Apogenix Gmbh | Composition comprising a mixture of cd95-fc isoforms |
| US20140065655A1 (en) * | 2012-09-05 | 2014-03-06 | Scivax Corporation | Screening method for substance acting on maintenance of epithelial properties of cell |
| MX363679B (es) * | 2013-04-29 | 2019-03-29 | Apogenix Ag | Metodo para diagnosticar cancer. |
| US10053510B2 (en) | 2013-05-24 | 2018-08-21 | Promis Neurosciences Inc. | FasR antibodies and methods of use |
| EP3094744A1 (en) * | 2014-01-15 | 2016-11-23 | Apogenix AG | Method of predicting the responsiveness of a cancer disease to treatment on the basis of dna methylation |
| EP3137909B1 (en) | 2014-04-29 | 2018-06-06 | Apogenix AG | Diagnostic anti-cd95l antibody |
| MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
| CN119015448A (zh) * | 2018-12-20 | 2024-11-26 | 芝加哥大学 | 与用于癌症疗法的治疗肽相关的方法和组合物 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5891434A (en) | 1991-06-17 | 1999-04-06 | Centocor, Inc. | Monoclonal antibodies to the APO-1 antigen |
| CA2109398A1 (en) | 1992-10-30 | 1994-05-01 | Alejandro A. Aruffo | Extracellular matrix receptor ligands that modulate leukocyte function |
| JPH08127594A (ja) | 1993-11-10 | 1996-05-21 | Mochida Pharmaceut Co Ltd | Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ |
| DE4447484C2 (de) | 1994-04-08 | 1997-07-17 | Deutsches Krebsforsch | Mittel zur Hemmung von Apoptose |
| US6060238A (en) * | 1995-02-13 | 2000-05-09 | The Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
| CA2215905A1 (en) | 1995-03-20 | 1996-09-26 | Sumitomo Electric Industries, Ltd. | Monoclonal antibody reacting specifically with fas ligand and process for producing the same |
| JP3925663B2 (ja) | 1995-06-30 | 2007-06-06 | 持田製薬株式会社 | 抗Ｆａｓリガンド抗体および該抗体を用いた測定法 |
| JPH09124509A (ja) | 1995-10-27 | 1997-05-13 | Sumitomo Electric Ind Ltd | 肝炎治療剤 |
| US6306395B1 (en) | 1996-05-02 | 2001-10-23 | Mochida Pharmaceutical Co., Ltd. | Fas antigen derivatives |
| EP0957166A4 (en) | 1996-09-02 | 2004-12-15 | Ko Okumura | HUMANIZED IMMUNOGLOBULIN SPECIFICALLY REACTING WITH A LIGAND Fas OR ONE OF ITS ACTIVE FRAGMENTS AND REGION FOR INDUCING APOPTOSIS BORN IN A LIGAND Fas |
| IL134578A0 (en) | 1997-09-18 | 2001-04-30 | Genentech Inc | DcR3 POLYPEPTIDE, A TNFR HOMOLOG |
| BR9909328A (pt) | 1998-03-30 | 2000-12-12 | Lilly Co Eli | Aplicações terapêuticas de polipeptìdeos flint maduros (mflint) ou opg3, um membro da superfamìlia dos receptores para tnf |
| US6348573B1 (en) * | 1998-04-27 | 2002-02-19 | The Regents Of The University Of Michigan | Compositions and methods for identifying apoptosis signaling pathway inhibitors and activators |
| US6846637B1 (en) | 1998-06-18 | 2005-01-25 | Imed Ab | Fas peptides and antibodies for modulating apoptosis |
| US20030170244A1 (en) * | 2001-12-21 | 2003-09-11 | Pluenneke John D. | Inhibition of Fas signaling |
| AU2003226370A1 (en) * | 2002-04-17 | 2003-11-03 | The Burnham Institute | Inhibition of fatty acid synthase by beta-lactones and other compounds for inhibition of cellular proliferation |
| EP1447093A1 (en) | 2003-02-14 | 2004-08-18 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Inhibition of the CD95 ligand/receptor system for the treatment of neurological disorders and injuries |
| PL1606318T3 (pl) * | 2003-03-26 | 2010-01-29 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Ulepszone białka fuzyjne FC |
| US7445794B1 (en) * | 2004-04-29 | 2008-11-04 | The Regents Of The University Of Colorado | Methods for treating human proliferative diseases, with a combination of fatty acid metabolism inhibitors and glycolytic inhibitors |
-
2007
- 2007-12-28 PT PT11190918T patent/PT2428252E/pt unknown
- 2007-12-28 EP EP20110190918 patent/EP2428252B1/en not_active Not-in-force
- 2007-12-28 US US12/521,625 patent/US9309320B2/en not_active Expired - Fee Related
- 2007-12-28 PL PL07857153T patent/PL2101877T3/pl unknown
- 2007-12-28 AU AU2007341631A patent/AU2007341631B9/en not_active Ceased
- 2007-12-28 PT PT78571536T patent/PT2101877E/pt unknown
- 2007-12-28 SI SI200731577T patent/SI2428252T1/sl unknown
- 2007-12-28 JP JP2009543400A patent/JP5558828B2/ja not_active Expired - Fee Related
- 2007-12-28 PL PL11190918T patent/PL2428252T3/pl unknown
- 2007-12-28 DK DK07857153T patent/DK2101877T3/da active
- 2007-12-28 WO PCT/EP2007/011461 patent/WO2008080623A2/en not_active Ceased
- 2007-12-28 ES ES11190918.0T patent/ES2523992T3/es active Active
- 2007-12-28 ES ES07857153T patent/ES2420582T3/es active Active
- 2007-12-28 EP EP07857153.6A patent/EP2101877B1/en active Active
- 2007-12-28 DK DK11190918T patent/DK2428252T3/en active
- 2007-12-28 CA CA2673868A patent/CA2673868C/en active Active
-
2014
- 2014-06-05 JP JP2014116401A patent/JP5893078B2/ja not_active Expired - Fee Related
-
2015
- 2015-02-02 CY CY20151100106T patent/CY1116006T1/el unknown
- 2015-04-30 US US14/700,521 patent/US9850308B2/en active Active
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