JP2010514682A - 化合物及びその使用 - Google Patents
化合物及びその使用 Download PDFInfo
- Publication number
- JP2010514682A JP2010514682A JP2009543160A JP2009543160A JP2010514682A JP 2010514682 A JP2010514682 A JP 2010514682A JP 2009543160 A JP2009543160 A JP 2009543160A JP 2009543160 A JP2009543160 A JP 2009543160A JP 2010514682 A JP2010514682 A JP 2010514682A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- arylalkyl
- heterocycloalkyl
- haloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *C(N(CC1)CCN1C1=Nc2ccccc2Sc2c1cccc2)=O Chemical compound *C(N(CC1)CCN1C1=Nc2ccccc2Sc2c1cccc2)=O 0.000 description 1
- JLOAJISUHPIQOX-UHFFFAOYSA-N C(C1)NCCN1C1=Nc2ccccc2Sc2c1cccc2 Chemical compound C(C1)NCCN1C1=Nc2ccccc2Sc2c1cccc2 JLOAJISUHPIQOX-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87096406P | 2006-12-20 | 2006-12-20 | |
PCT/US2007/088036 WO2008079838A1 (fr) | 2006-12-20 | 2007-12-19 | Composés et leurs utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010514682A true JP2010514682A (ja) | 2010-05-06 |
JP2010514682A5 JP2010514682A5 (fr) | 2010-12-16 |
Family
ID=39562910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009543160A Pending JP2010514682A (ja) | 2006-12-20 | 2007-12-19 | 化合物及びその使用 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20100093699A1 (fr) |
EP (1) | EP2120563A4 (fr) |
JP (1) | JP2010514682A (fr) |
CN (1) | CN101616585A (fr) |
WO (1) | WO2008079838A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009151393A1 (fr) * | 2008-06-14 | 2009-12-17 | Astrazeneca Ab | Nouveaux dérivés de la 11-pipérazin-l-yldibenzo[b,f][l,4]thiazépine pour traiter au moins un syndrome ou un état associé à la schizophrénie et autres troubles psychotiques |
BRPI0818376A2 (pt) | 2007-10-24 | 2015-04-14 | Dow Agrosciences Llc | Processo aperfeiçoado para a fabricação dos ésteres do ácido (r)-(+)-2-(4-(4-ciano-2-fluorofenóxi) fenóxi propiônico |
JP5544024B2 (ja) | 2009-12-31 | 2014-07-09 | ケムファーム・インコーポレーテッド | クエチアピンのアミノ酸結合体、その製造法及び使用法 |
PL2544536T3 (pl) * | 2010-03-11 | 2019-05-31 | Kempharm Inc | Koniugaty kwasów tłuszczowych z kwetiapiną, sposób ich wytwarzania i stosowania |
EP2567959B1 (fr) | 2011-09-12 | 2014-04-16 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
CN110878048B (zh) * | 2018-09-06 | 2023-03-17 | 中国科学院上海药物研究所 | 作为防治精神障碍疾病的苯胺类化合物 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS638378A (ja) * | 1986-03-27 | 1988-01-14 | アイ・シ−・アイ・アメリカス・インコ−ポレイテツド | ジベンゾチアゼピン化合物、その製造法、ならびに該化合物を含有する、抗精神作用および神経弛緩作用を有する製薬学的組成物 |
JPH0565257A (ja) * | 1991-07-05 | 1993-03-19 | Hokuriku Seiyaku Co Ltd | 多環式化合物及びその用途 |
WO2005002586A1 (fr) * | 2003-07-02 | 2005-01-13 | Astrazeneca Ab | Metabolite de quetiapine |
US20060063754A1 (en) * | 2004-09-21 | 2006-03-23 | Edgar Dale M | Methods of treating a sleep disorder |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4547505A (en) * | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
EP1495008A1 (fr) * | 2003-02-22 | 2005-01-12 | Teva Pharmaceutical Industries Limited | Synthese de la quetiapine et sels acceptables d'un point de vue pharmaceutique de celle-ci |
US20060217366A1 (en) * | 2003-07-02 | 2006-09-28 | Astrazeneca Ab | Method of treating schizophrenia and other disorders |
WO2007053618A1 (fr) * | 2005-10-31 | 2007-05-10 | Acadia Pharmaceuticals Inc. | Promédicaments d'agonistes muscariniques et méthodes de traitement de troubles neuropsychiatriques |
-
2007
- 2007-12-19 US US12/520,133 patent/US20100093699A1/en not_active Abandoned
- 2007-12-19 WO PCT/US2007/088036 patent/WO2008079838A1/fr active Application Filing
- 2007-12-19 EP EP07855245A patent/EP2120563A4/fr not_active Withdrawn
- 2007-12-19 JP JP2009543160A patent/JP2010514682A/ja active Pending
- 2007-12-19 CN CN200780051537A patent/CN101616585A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS638378A (ja) * | 1986-03-27 | 1988-01-14 | アイ・シ−・アイ・アメリカス・インコ−ポレイテツド | ジベンゾチアゼピン化合物、その製造法、ならびに該化合物を含有する、抗精神作用および神経弛緩作用を有する製薬学的組成物 |
JPH0565257A (ja) * | 1991-07-05 | 1993-03-19 | Hokuriku Seiyaku Co Ltd | 多環式化合物及びその用途 |
WO2005002586A1 (fr) * | 2003-07-02 | 2005-01-13 | Astrazeneca Ab | Metabolite de quetiapine |
US20060063754A1 (en) * | 2004-09-21 | 2006-03-23 | Edgar Dale M | Methods of treating a sleep disorder |
Non-Patent Citations (1)
Title |
---|
JPN6013005284; J. Med. Chem. Vol.44, 2001, P.372-389 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008079838A1 (fr) | 2008-07-03 |
EP2120563A4 (fr) | 2011-04-27 |
US20100093699A1 (en) | 2010-04-15 |
EP2120563A1 (fr) | 2009-11-25 |
CN101616585A (zh) | 2009-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101026 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101026 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130212 |
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A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20130709 |