PL2544536T3 - Koniugaty kwasów tłuszczowych z kwetiapiną, sposób ich wytwarzania i stosowania - Google Patents

Koniugaty kwasów tłuszczowych z kwetiapiną, sposób ich wytwarzania i stosowania

Info

Publication number
PL2544536T3
PL2544536T3 PL11753975T PL11753975T PL2544536T3 PL 2544536 T3 PL2544536 T3 PL 2544536T3 PL 11753975 T PL11753975 T PL 11753975T PL 11753975 T PL11753975 T PL 11753975T PL 2544536 T3 PL2544536 T3 PL 2544536T3
Authority
PL
Poland
Prior art keywords
quetiapine
making
same
fatty acid
acid conjugates
Prior art date
Application number
PL11753975T
Other languages
English (en)
Inventor
Travis Mickle
Sven Guenther
Sanjib Bera
Original Assignee
Kempharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kempharm Inc filed Critical Kempharm Inc
Publication of PL2544536T3 publication Critical patent/PL2544536T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/36Seven-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL11753975T 2010-03-11 2011-03-09 Koniugaty kwasów tłuszczowych z kwetiapiną, sposób ich wytwarzania i stosowania PL2544536T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31297710P 2010-03-11 2010-03-11
EP11753975.9A EP2544536B1 (en) 2010-03-11 2011-03-09 Fatty acid conjugates of quetiapine, process for making and using the same
PCT/US2011/027658 WO2011112657A1 (en) 2010-03-11 2011-03-09 Fatty acid conjugates of quetiapine, process for making and using the same

Publications (1)

Publication Number Publication Date
PL2544536T3 true PL2544536T3 (pl) 2019-05-31

Family

ID=44560214

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11753975T PL2544536T3 (pl) 2010-03-11 2011-03-09 Koniugaty kwasów tłuszczowych z kwetiapiną, sposób ich wytwarzania i stosowania

Country Status (14)

Country Link
US (7) US8900604B2 (pl)
EP (2) EP2544536B1 (pl)
CY (1) CY1121106T1 (pl)
DK (1) DK2544536T3 (pl)
ES (1) ES2705233T3 (pl)
HR (1) HRP20190057T1 (pl)
HU (1) HUE042945T2 (pl)
LT (1) LT2544536T (pl)
PL (1) PL2544536T3 (pl)
PT (1) PT2544536T (pl)
RS (1) RS58335B1 (pl)
SI (1) SI2544536T1 (pl)
TR (1) TR201900067T4 (pl)
WO (1) WO2011112657A1 (pl)

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AU2010336981B2 (en) 2009-12-31 2014-04-10 Kempharm, Inc. Amino acid conjugates of quetiapine, process for making and using the same
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US20140161748A1 (en) * 2011-05-13 2014-06-12 University Of Manitoba Methods for treating sun-exposed skin
US9321014B2 (en) * 2011-12-16 2016-04-26 Bl Technologies, Inc. Hollow fiber membrane with compatible reinforcements
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WO2014031595A1 (en) 2012-08-21 2014-02-27 Janssen Pharmaceutica Nv Haptens of paliperidone
JP6374387B2 (ja) 2012-08-21 2018-08-15 ヤンセン ファーマシューティカ エヌ.ベー. リスペリドンハプテンへの抗体及びその使用
US9465041B2 (en) 2012-08-21 2016-10-11 Janssen Pharmaceutica Nv Antibodies to paliperidone and use thereof
WO2014031587A1 (en) 2012-08-21 2014-02-27 Janssen Pharmaceutica Nv Haptens of olanzipine
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AU2013305904B2 (en) * 2012-08-21 2017-08-17 Saladax Biomedical Inc. Antibodies to quetiapine haptens and use thereof
TR201816416T4 (tr) 2012-08-21 2018-11-21 Janssen Pharmaceutica Nv Risperidona yönelik antikorlar ve bunların kullanımı.
JP6131500B2 (ja) 2012-08-21 2017-05-24 ヤンセン ファーマシューティカ エヌ.ベー. リスペリドン及びパリペリドンのハプテン
CN108484496B (zh) 2012-08-21 2022-03-22 詹森药业有限公司 阿立哌唑半抗原及其在免疫测定中的应用
US9304126B2 (en) * 2012-08-21 2016-04-05 Janssen Pharmaceutica Nv Haptens of quetiapine
TR201910347T4 (tr) 2012-08-21 2019-07-22 Janssen Pharmaceutica Nv Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı.
JP6389176B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ.ベー. アリピプラゾールハプテンに対する抗体及びその使用
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス,インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
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WO2014057439A2 (en) * 2012-10-13 2014-04-17 Mahesh Kandula Compositions and methods for the treatment of neurological diseases and its associated complications
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AU2016372069A1 (en) 2015-12-17 2018-06-07 Saladax Biomedical Inc. Antibodies to risperidone and use thereof
EP3390455A1 (en) 2015-12-17 2018-10-24 Janssen Pharmaceutica NV Antibodies to quetiapine and use thereof
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WO2018045094A1 (en) * 2016-08-31 2018-03-08 The Board Of Trustees Of The Leland Stanford Junior University Ladderane lipid compounds and liposomes and methods of preparing and using the same

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Also Published As

Publication number Publication date
US20170247368A1 (en) 2017-08-31
LT2544536T (lt) 2019-02-25
HRP20190057T1 (hr) 2019-03-22
US20110223207A1 (en) 2011-09-15
WO2011112657A1 (en) 2011-09-15
US20170042906A1 (en) 2017-02-16
EP2544536A4 (en) 2013-08-14
US20130045247A1 (en) 2013-02-21
US9889198B2 (en) 2018-02-13
EP2544536A1 (en) 2013-01-16
US20170246301A1 (en) 2017-08-31
HUE042945T2 (hu) 2019-07-29
TR201900067T4 (tr) 2019-02-21
US8900604B2 (en) 2014-12-02
US9511149B2 (en) 2016-12-06
ES2705233T3 (es) 2019-03-22
CY1121106T1 (el) 2019-12-11
SI2544536T1 (sl) 2019-03-29
RS58335B1 (sr) 2019-03-29
EP3476218A1 (en) 2019-05-01
US9890150B2 (en) 2018-02-13
EP2544536B1 (en) 2018-12-12
PT2544536T (pt) 2019-01-23
US20150044261A1 (en) 2015-02-12
US20130158007A1 (en) 2013-06-20
DK2544536T3 (en) 2019-02-04

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