JP2010513259A5 - - Google Patents

Info

Publication number

JP2010513259A5

JP2010513259A5 JP2009540868A JP2009540868A JP2010513259A5 JP 2010513259 A5 JP2010513259 A5 JP 2010513259A5 JP 2009540868 A JP2009540868 A JP 2009540868A JP 2009540868 A JP2009540868 A JP 2009540868A JP 2010513259 A5 JP2010513259 A5 JP 2010513259A5

Authority

JP

Japan

Prior art keywords

carbohydrate

fat

nutritional

composition

formulation

Prior art date

2007-12-14

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 239000000203 mixture Substances 0.000 claims 24
• 235000016709 nutrition Nutrition 0.000 claims 18
• 235000014633 carbohydrates Nutrition 0.000 claims 14
• 150000001720 carbohydrates Chemical class 0.000 claims 14
• 239000003925 fat Substances 0.000 claims 14
• 229940024606 amino acid Drugs 0.000 claims 12
• 235000001014 amino acid Nutrition 0.000 claims 12
• 150000001413 amino acids Chemical class 0.000 claims 12
• 239000000047 product Substances 0.000 claims 10
• 238000009472 formulation Methods 0.000 claims 9
• 238000002360 preparation method Methods 0.000 claims 7
• DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 6
• HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 6
• AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 6
• OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 6
• KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 6
• 208000012202 Pervasive developmental disease Diseases 0.000 claims 6
• 208000029560 autism spectrum disease Diseases 0.000 claims 6
• 235000018102 proteins Nutrition 0.000 claims 6
• 102000004169 proteins and genes Human genes 0.000 claims 6
• 108090000623 proteins and genes Proteins 0.000 claims 6
• XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims 6
• 235000013325 dietary fiber Nutrition 0.000 claims 5
• 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 claims 5
• MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 4
• PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims 3
• QDGAVODICPCDMU-UHFFFAOYSA-N 2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid Chemical compound OC(=O)C(N)CC1=CC=CC(N(CCCl)CCCl)=C1 QDGAVODICPCDMU-UHFFFAOYSA-N 0.000 claims 3
• 241000894006 Bacteria Species 0.000 claims 3
• CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 claims 3
• QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 claims 3
• 239000004471 Glycine Substances 0.000 claims 3
• QNAYBMKLOCPYGJ-UWTATZPHSA-N L-Alanine Natural products C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 claims 3
• CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 claims 3
• FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 claims 3
• QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 3
• ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 3
• 229930064664 L-arginine Natural products 0.000 claims 3
• 235000014852 L-arginine Nutrition 0.000 claims 3
• CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 3
• LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 claims 3
• 235000019393 L-cystine Nutrition 0.000 claims 3
• 239000004158 L-cystine Substances 0.000 claims 3
• AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 3
• 229930182844 L-isoleucine Natural products 0.000 claims 3
• FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 3
• 229930195722 L-methionine Natural products 0.000 claims 3
• 239000004473 Threonine Substances 0.000 claims 3
• 229960003767 alanine Drugs 0.000 claims 3
• 229960005261 aspartic acid Drugs 0.000 claims 3
• 229960003067 cystine Drugs 0.000 claims 3
• 229960002449 glycine Drugs 0.000 claims 3
• 229960002885 histidine Drugs 0.000 claims 3
• 229960000310 isoleucine Drugs 0.000 claims 3
• 229960004452 methionine Drugs 0.000 claims 3
• 239000006041 probiotic Substances 0.000 claims 3
• 230000000529 probiotic effect Effects 0.000 claims 3
• 235000018291 probiotics Nutrition 0.000 claims 3
• IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 claims 3
• WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 claims 3
• 229960003080 taurine Drugs 0.000 claims 3
• 229960002898 threonine Drugs 0.000 claims 3
• 229960004441 tyrosine Drugs 0.000 claims 3
• 229960004295 valine Drugs 0.000 claims 3
• 208000036640 Asperger disease Diseases 0.000 claims 2
• 201000006062 Asperger syndrome Diseases 0.000 claims 2
• 206010003805 Autism Diseases 0.000 claims 2
• 208000020706 Autistic disease Diseases 0.000 claims 2
• ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 2
• ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 2
• 229930182816 L-glutamine Natural products 0.000 claims 2
• 208000006289 Rett Syndrome Diseases 0.000 claims 2
• 208000036353 Rett disease Diseases 0.000 claims 2
• 235000005911 diet Nutrition 0.000 claims 2
• 230000037213 diet Effects 0.000 claims 2
• 229910052500 inorganic mineral Inorganic materials 0.000 claims 2
• 239000011707 mineral Substances 0.000 claims 2
• 229960001153 serine Drugs 0.000 claims 2
• 235000013343 vitamin Nutrition 0.000 claims 2
• 229940088594 vitamin Drugs 0.000 claims 2
• 229930003231 vitamin Natural products 0.000 claims 2
• 239000011782 vitamin Substances 0.000 claims 2
• VOOGILFUHUXBEV-ZBRNBAAYSA-N (2s)-2-amino-3-hydroxypropanoic acid;(2s)-pyrrolidine-2-carboxylic acid Chemical compound OC[C@H](N)C(O)=O.OC(=O)[C@@H]1CCCN1 VOOGILFUHUXBEV-ZBRNBAAYSA-N 0.000 claims 1
• 230000007812 deficiency Effects 0.000 claims 1
• 235000015872 dietary supplement Nutrition 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 235000019197 fats Nutrition 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1