ES2555257T3 - Fórmula infantil baja en proteínas con aumento de los aminoácidos esenciales - Google Patents
Fórmula infantil baja en proteínas con aumento de los aminoácidos esenciales Download PDFInfo
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- ES2555257T3 ES2555257T3 ES11712054.3T ES11712054T ES2555257T3 ES 2555257 T3 ES2555257 T3 ES 2555257T3 ES 11712054 T ES11712054 T ES 11712054T ES 2555257 T3 ES2555257 T3 ES 2555257T3
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- protein
- amino acids
- infant formula
- essential amino
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- 102000004169 proteins and genes Human genes 0.000 title abstract description 10
- 108090000623 proteins and genes Proteins 0.000 title abstract description 10
- 235000013350 formula milk Nutrition 0.000 title abstract description 3
- 235000020776 essential amino acid Nutrition 0.000 title 1
- 239000003797 essential amino acid Substances 0.000 title 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract description 5
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract description 4
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract description 3
- 235000014633 carbohydrates Nutrition 0.000 abstract description 3
- 150000001720 carbohydrates Chemical class 0.000 abstract description 3
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- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract description 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract description 2
- 229940024606 amino acid Drugs 0.000 abstract description 2
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- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract description 2
- 239000004474 valine Substances 0.000 abstract description 2
- OCUSNPIJIZCRSZ-ZTZWCFDHSA-N (2s)-2-amino-3-methylbutanoic acid;(2s)-2-amino-4-methylpentanoic acid;(2s,3s)-2-amino-3-methylpentanoic acid Chemical compound CC(C)[C@H](N)C(O)=O.CC[C@H](C)[C@H](N)C(O)=O.CC(C)C[C@H](N)C(O)=O OCUSNPIJIZCRSZ-ZTZWCFDHSA-N 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 description 6
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 2
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- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
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- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 2
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- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 description 1
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- 239000004395 L-leucine Substances 0.000 description 1
- 235000019454 L-leucine Nutrition 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
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- 108010046377 Whey Proteins Proteins 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 235000021120 animal protein Nutrition 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 229960005261 aspartic acid Drugs 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 229960005190 phenylalanine Drugs 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
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- 229960002898 threonine Drugs 0.000 description 1
- 229960004799 tryptophan Drugs 0.000 description 1
- 229960004441 tyrosine Drugs 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C11/00—Milk substitutes, e.g. coffee whitener compositions
- A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
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- A—HUMAN NECESSITIES
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/332—Promoters of weight control and weight loss
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
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- A23V2250/0626—Isoleucine
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pediatric Medicine (AREA)
- Diabetes (AREA)
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- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Dairy Products (AREA)
Abstract
Fórmula infantil que comprende proteínas, carbohidratos digeribles y grasas, donde la proteína comprende aminoácidos de leucina, isoleucina y valina en una proporción en peso leucina:isoleucina:valina entre (1,1-1,5):(0,9- 1,1):1,0, y donde el contenido de proteína es entre 1,3 y 1,9 g proteína/100 kcal.
Description
L-VALINA 109,7 mg L-ASPARAGINA 0 mg L-CITRULINA 0 mg L-CARNITINA 1,2 mg
Ejemplo 4. Fórmula infantil que comprende aminoácidos de proteínas de leche intactas según la invención.
[0062] COMPONENTE UNIDAD Por 100 kcal
- 1.
- Proteínas (equivalente) g 1,4
- 2.
- Carbohidratos g 11,7
- Azúcares g 11,5
3. Grasas g 5,12
- Saturadas g 2,22
- 4.
- Fibra, dietética g 0,856
- 5.
- Sodio g 25,8
5
D. Propiedades nutricionales
Porcentajes de energía: 10 [0063]
- 1. Proteínas (equivalente) En%
- 5,6
- 2. Carbohidratos
- En% 46,4 *
- 3. Grasas
- En% 46,3
- 4. Fibra
- En% 1,7
- Total
- En% 100
* Incluyendo ácidos orgánicos y polioles
- 15
- E. Composición [0064]
- 1. Proteínas (equivalente), total
- g 1,4
- 20
- - Nitrógeno (Proteína) - Proteína animal g g 0,224 1,428
- Proteína de suero de leche
- g 0,861
13
[0065]
L-Alanina
mg 65,8
L-Arginina mg 46,9
Ácido L-Aspártico / L-mg 116,2
Asparagina
L-Cist(e)ina mg 25,2
Ácido L-Glutámico / L-mg 263,2
Glutamina
Glicina mg 29,4
L-Histidine mg 33,6
L-Isoleucina mg 109,7 (84,7 de proteína)
L-Leucina mg 158,2
L-Lisina mg 136,5
L-Metionina mg 37,1
L-Fenilalanina mg 63,7
L-Prolina mg 110,6
L-Serina mg 86,8
L-Treonina mg 86,8
L-Triptófano mg 23,1
L-Tirosina mg 59,5
L-Valina mg 114.6
(89,6 de proteínas) proporción leucina:isoleucina:valina=1,4:1,0:1,0
15
Claims (1)
-
imagen1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
WOPCT/NL2010/050156 | 2010-03-26 | ||
PCT/NL2010/050156 WO2011119023A1 (en) | 2010-03-26 | 2010-03-26 | Low protein infant formula with increased essential amino acids |
PCT/NL2011/050207 WO2011119033A1 (en) | 2010-03-26 | 2011-03-25 | Low protein infant formula with increased essential amino acids |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2555257T3 true ES2555257T3 (es) | 2015-12-30 |
ES2555257T5 ES2555257T5 (es) | 2022-02-25 |
Family
ID=43216285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES11712054T Active ES2555257T5 (es) | 2010-03-26 | 2011-03-25 | Fórmula infantil baja en proteínas con aumento de los aminoácidos esenciales |
Country Status (12)
Country | Link |
---|---|
US (3) | US8987196B2 (es) |
EP (2) | EP2552242B2 (es) |
CN (2) | CN102892309B (es) |
BR (1) | BR112012024102B1 (es) |
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HU (1) | HUE025633T2 (es) |
MY (2) | MY160552A (es) |
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EP2831100A4 (en) * | 2012-03-26 | 2016-02-10 | Pronutria Inc | NUTRIENT PROTEINS AND METHODS |
BR112015011853B1 (pt) * | 2012-11-23 | 2021-02-09 | N.V. Nutricia | fórmula infantil ou de acompanhamento que compreende uma composição proteinácea |
JP6520712B2 (ja) | 2013-09-24 | 2019-05-29 | 味の素株式会社 | 糖アミノ酸およびその用途 |
AU2014324901A1 (en) | 2013-09-25 | 2016-05-19 | Axcella Health Inc. | Compositions and formulations for prevention and treatment of diabetes and obesity, and methods of production and use thereof in glucose and caloric control |
RU2687038C1 (ru) | 2013-11-29 | 2019-05-06 | Нестек С.А. | Соответствующие возрастным потребностям питательные композиции с различным содержанием белка |
EP3082463B1 (en) | 2013-11-29 | 2019-05-01 | Nestec S.A. | Use of nutritional compositions having a low protein amount |
CN113331426A (zh) | 2014-04-08 | 2021-09-03 | 雅培公司 | 使用人乳寡糖增强对病原体的粘膜先天免疫反应和/或检测的方法 |
WO2015154259A1 (en) * | 2014-04-09 | 2015-10-15 | Nestle (China) Ltd. | Gender specific synthetic nutritional compositions and nutritional systems comprising them |
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EP3145333B1 (en) | 2014-05-19 | 2020-11-04 | N.V. Nutricia | Infant formula with optimised amino acid profiles |
CN104012659B (zh) * | 2014-06-26 | 2016-04-20 | 中恩(天津)营养科技有限公司 | 一种用于苯丙酮尿症儿童的配方粉及其制备方法 |
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WO2016091265A1 (en) * | 2014-12-08 | 2016-06-16 | Glycom A/S | Synthetic composition for treating metabolic disorders |
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CN109963569A (zh) * | 2016-10-05 | 2019-07-02 | 科尔生公司 | 用基于氨基酸的营养组合物喂养的婴儿或幼儿中肠道微生物群组成的正常化 |
JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
DE102017200007A1 (de) | 2017-01-02 | 2018-07-05 | Schott Ag | Spritze mit unterschiedlichen Materialien |
US10682325B2 (en) | 2017-08-14 | 2020-06-16 | Axcella Health Inc. | Compositions and methods for the treatment of liver diseases and disorders associated with one or both of hyperammonemia or muscle wasting |
GB2566971B (en) * | 2017-09-28 | 2020-12-02 | Mjn Us Holdings Llc | Infant formula having decreased protein content |
US20200319203A1 (en) * | 2017-12-19 | 2020-10-08 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for fetal growth |
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HUE025633T2 (en) | 2016-04-28 |
MY177379A (en) | 2020-09-14 |
RU2012145528A (ru) | 2014-05-20 |
US10136668B2 (en) | 2018-11-27 |
RU2559432C2 (ru) | 2015-08-10 |
PT2552242E (pt) | 2016-01-08 |
WO2011119033A1 (en) | 2011-09-29 |
PL2552242T3 (pl) | 2016-03-31 |
BR112012024102B1 (pt) | 2020-01-28 |
EP2552242B2 (en) | 2021-09-01 |
MY160552A (en) | 2017-03-15 |
CN107821606A (zh) | 2018-03-23 |
EP2552242B1 (en) | 2015-09-09 |
CN107821606B (zh) | 2021-09-14 |
EP2984942A1 (en) | 2016-02-17 |
US20170181460A1 (en) | 2017-06-29 |
EP2552242A1 (en) | 2013-02-06 |
EP2984942B1 (en) | 2020-04-22 |
DK2552242T3 (en) | 2015-12-21 |
PL2552242T5 (pl) | 2021-11-08 |
US20130079276A1 (en) | 2013-03-28 |
CN102892309A (zh) | 2013-01-23 |
WO2011119023A1 (en) | 2011-09-29 |
DK2984942T3 (da) | 2020-06-15 |
ES2555257T5 (es) | 2022-02-25 |
US20150352178A1 (en) | 2015-12-10 |
US8987196B2 (en) | 2015-03-24 |
US9492498B2 (en) | 2016-11-15 |
DK2552242T4 (da) | 2021-11-01 |
CN102892309B (zh) | 2016-01-27 |
BR112012024102A2 (pt) | 2015-09-01 |
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