JP2010512306A - 抗炎症特性が増強され、細胞毒性特性が減少したポリペプチドおよび関連する方法 - Google Patents

抗炎症特性が増強され、細胞毒性特性が減少したポリペプチドおよび関連する方法 Download PDF

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JP2010512306A
JP2010512306A JP2009534723A JP2009534723A JP2010512306A JP 2010512306 A JP2010512306 A JP 2010512306A JP 2009534723 A JP2009534723 A JP 2009534723A JP 2009534723 A JP2009534723 A JP 2009534723A JP 2010512306 A JP2010512306 A JP 2010512306A
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region
sialic acid
antibody
igg
polypeptide
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JP2009534723A
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Japanese (ja)
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JP2010512306A5 (enExample
Inventor
ニンマージャン,フォーク
佳賢 金子
ラベッチ,ジェフリー,ブイ.
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Rockefeller University
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Rockefeller University
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Priority claimed from PCT/US2006/041791 external-priority patent/WO2007055916A2/en
Priority claimed from PCT/US2007/008396 external-priority patent/WO2007117505A2/en
Application filed by Rockefeller University filed Critical Rockefeller University
Priority claimed from PCT/US2007/072771 external-priority patent/WO2008057634A2/en
Publication of JP2010512306A publication Critical patent/JP2010512306A/ja
Publication of JP2010512306A5 publication Critical patent/JP2010512306A5/ja
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009534723A 2006-10-27 2007-07-03 抗炎症特性が増強され、細胞毒性特性が減少したポリペプチドおよび関連する方法 Pending JP2010512306A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2006/041791 WO2007055916A2 (en) 2005-11-07 2006-10-27 Reagents, methods and systems for selecting a cytotoxic antibody or variant thereof
PCT/US2007/008396 WO2007117505A2 (en) 2006-04-05 2007-04-03 Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
PCT/US2007/072771 WO2008057634A2 (en) 2006-10-26 2007-07-03 Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods

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JP2010512306A true JP2010512306A (ja) 2010-04-22
JP2010512306A5 JP2010512306A5 (enExample) 2012-08-16

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JP (1) JP2010512306A (enExample)
CA (1) CA2666308C (enExample)
IL (1) IL197920A0 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014508759A (ja) * 2011-02-24 2014-04-10 サノフイ シアリル化抗体の生産の方法
JP2016512426A (ja) * 2013-03-11 2016-04-28 ジェンザイム・コーポレーション 糖類工学による部位特異的抗体−薬物コンジュゲーション
KR20210060359A (ko) * 2019-11-18 2021-05-26 건국대학교 산학협력단 시알산화된 면역글로불린을 유효성분으로 포함하는 염증성 질환의 치료용 조성물
US11186638B2 (en) 2011-09-12 2021-11-30 Genzyme Corporation Anti-αβTCR antibody
US11697690B2 (en) 2014-03-19 2023-07-11 Genzyme Corporation Site-specific glycoengineering of targeting moieties
US12365734B2 (en) 2019-04-03 2025-07-22 Genzyme Corporation Anti-alpha beta TCR binding polypeptides with reduced fragmentation
US12503498B2 (en) 2020-10-08 2025-12-23 Genzyme Corporation Fc containing polypeptides with altered glycosylation and reduced effector function

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116705170A (zh) * 2023-05-08 2023-09-05 宁波市医疗中心李惠利医院 基于maldi-tof ms联合lstm的大肠埃希菌菌株水平鉴定方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001507215A (ja) * 1997-01-16 2001-06-05 サイテル コーポレイション 組換え糖タンパク質のインビトロでの実用的なシアリル化
WO2002030954A1 (en) * 2000-10-06 2002-04-18 Kyowa Hakko Kogyo Co., Ltd. Method of purifying antibody
JP2002541854A (ja) * 1999-04-15 2002-12-10 クルセル ホラント ベスローテン フェンノートシャップ ヒト細胞における組み換え蛋白質の生産

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001507215A (ja) * 1997-01-16 2001-06-05 サイテル コーポレイション 組換え糖タンパク質のインビトロでの実用的なシアリル化
JP2002541854A (ja) * 1999-04-15 2002-12-10 クルセル ホラント ベスローテン フェンノートシャップ ヒト細胞における組み換え蛋白質の生産
WO2002030954A1 (en) * 2000-10-06 2002-04-18 Kyowa Hakko Kogyo Co., Ltd. Method of purifying antibody

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6012037052; Biochem Biophys Res Commun. Vol.286, No.2, 20010817, p.243-249 *
JPN6012037054; Science Vol.313, No.5787, 20060804, p.670-673 *
JPN6012037058; Science Vol.313, No.5787, 20060804, p.1-21 *
JPN6013012266; Mol Immunol. Vol.44, No.7, 20061011, p.1524-1534 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014508759A (ja) * 2011-02-24 2014-04-10 サノフイ シアリル化抗体の生産の方法
US11186638B2 (en) 2011-09-12 2021-11-30 Genzyme Corporation Anti-αβTCR antibody
JP2016512426A (ja) * 2013-03-11 2016-04-28 ジェンザイム・コーポレーション 糖類工学による部位特異的抗体−薬物コンジュゲーション
US11807690B2 (en) 2013-03-11 2023-11-07 Genzyme Corporation Hyperglycosylated binding polypeptides
US12110338B2 (en) 2013-03-11 2024-10-08 Genzyme Corporation Site-specific antibody-drug conjugation through glycoengineering
US11697690B2 (en) 2014-03-19 2023-07-11 Genzyme Corporation Site-specific glycoengineering of targeting moieties
US12365734B2 (en) 2019-04-03 2025-07-22 Genzyme Corporation Anti-alpha beta TCR binding polypeptides with reduced fragmentation
KR20210060359A (ko) * 2019-11-18 2021-05-26 건국대학교 산학협력단 시알산화된 면역글로불린을 유효성분으로 포함하는 염증성 질환의 치료용 조성물
KR102549282B1 (ko) * 2019-11-18 2023-06-30 건국대학교 산학협력단 시알산화된 면역글로불린을 유효성분으로 포함하는 염증성 질환의 치료용 조성물
US12503498B2 (en) 2020-10-08 2025-12-23 Genzyme Corporation Fc containing polypeptides with altered glycosylation and reduced effector function

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IL197920A0 (en) 2011-08-01
CA2666308C (en) 2014-09-23
CA2666308A1 (en) 2008-05-15

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