JP2010511041A - インジブリンを含むインドリル−３−グリオキシル酸誘導体の癌を処置するための単独またはさらなる薬剤との組み合わせでの使用 - Google Patents

インジブリンを含むインドリル−３−グリオキシル酸誘導体の癌を処置するための単独またはさらなる薬剤との組み合わせでの使用 Download PDF

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JP2010511041A
JP2010511041A JP2009539288A JP2009539288A JP2010511041A JP 2010511041 A JP2010511041 A JP 2010511041A JP 2009539288 A JP2009539288 A JP 2009539288A JP 2009539288 A JP2009539288 A JP 2009539288A JP 2010511041 A JP2010511041 A JP 2010511041A
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cancer
alkyl
indibulin
halogen
indolyl
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JP2010511041A5 (https=
Inventor
バーバラ ピー． ウォルナー，
ブライアン エリック シュワルツ，
フィリップ ビー． コマルニツキー，
ゲラルド バシェル，
ベンハルド クッチャー，
ゲルハルト ラーブ，
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Ziopharm Oncology Inc
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Ziopharm Oncology Inc
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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JP2009539288A 2006-11-28 2007-11-27 インジブリンを含むインドリル−３−グリオキシル酸誘導体の癌を処置するための単独またはさらなる薬剤との組み合わせでの使用 Pending JP2010511041A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86145406P 2006-11-28 2006-11-28
US87287406P 2006-12-05 2006-12-05
US92226807P 2007-04-06 2007-04-06
US99382907P 2007-09-14 2007-09-14
US15807P 2007-10-23 2007-10-23
PCT/US2007/024438 WO2008066807A1 (en) 2006-11-28 2007-11-27 Use of indolyl-3-glyoxylic acid derivatives including indibulin, alone or in combination with further agents for treating cancer

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JP2010511041A true JP2010511041A (ja) 2010-04-08
JP2010511041A5 JP2010511041A5 (https=) 2012-01-12

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US (3) US20080241274A1 (https=)
EP (1) EP2091532A1 (https=)
JP (1) JP2010511041A (https=)
AU (1) AU2007325797B2 (https=)
CA (1) CA2670778A1 (https=)
WO (1) WO2008066807A1 (https=)

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US8884020B2 (en) 2006-08-07 2014-11-11 Ironwood Pharmaceuticals, Inc. Indole compounds
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen
CN105198788A (zh) * 2015-09-30 2015-12-30 蒋军荣 一种吲哚氧代乙酰(n-二芳甲基)哌嗪衍生物及其制备方法和应用
CN116898845B (zh) * 2023-08-08 2025-11-28 武汉大学人民医院（湖北省人民医院） 吲哚布芬在制备非酒精性脂肪肝药物中的应用

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JP2003510274A (ja) * 1999-09-28 2003-03-18 バクスター ヘルスケア ソシエテ アノニム 治療上重要な特性を有するインドリル−３−グリオキシル酸誘導体
JP2004504398A (ja) * 2000-07-25 2004-02-12 ノブスファルマ　ソチエタ　ペル　アツィオニ 抗腫瘍活性を有する２−（１ｈ−インドール−３−イル）−２−オキソ−酢酸アミド
JP2005524210A (ja) * 2002-04-30 2005-08-11 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ スイッチ
JP2007505914A (ja) * 2003-09-18 2007-03-15 コンビナトアールエックス インコーポレーティッド 新生物の治療のための薬物の併用方法
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