JP2010509205A - Ｐｏｓｈ及びｐｏｓｈ−ａｐ阻害剤としてのピリミジン誘導体 - Google Patents
Ｐｏｓｈ及びｐｏｓｈ−ａｐ阻害剤としてのピリミジン誘導体 Download PDFInfo
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- JP2010509205A JP2010509205A JP2009535189A JP2009535189A JP2010509205A JP 2010509205 A JP2010509205 A JP 2010509205A JP 2009535189 A JP2009535189 A JP 2009535189A JP 2009535189 A JP2009535189 A JP 2009535189A JP 2010509205 A JP2010509205 A JP 2010509205A
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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| US85737806P | 2006-11-07 | 2006-11-07 | |
| US95983107P | 2007-07-17 | 2007-07-17 | |
| PCT/IL2007/001356 WO2008056356A2 (en) | 2006-11-07 | 2007-11-07 | Pyrimidine derivatives as posh and posh-ap inhibitors |
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| JP2010509205A true JP2010509205A (ja) | 2010-03-25 |
| JP2010509205A5 JP2010509205A5 (https=) | 2010-12-24 |
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| CA (1) | CA2668859A1 (https=) |
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| JP2013512234A (ja) * | 2009-11-30 | 2013-04-11 | プロテオロジクス リミテッド | 小型ピリミジン誘導体およびその使用の方法 |
| WO2013088445A1 (en) * | 2011-12-13 | 2013-06-20 | Proteologics Ltd | Pyrimidine derivatives for treatment of inflammatory diseases |
| GB201415688D0 (en) * | 2014-09-04 | 2014-10-22 | Univ Edinburgh | Method and Systems |
| JP6993318B2 (ja) * | 2015-07-15 | 2022-02-03 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | Ｂ型肝炎ウイルス複製の調節 |
| US12059413B2 (en) | 2016-11-02 | 2024-08-13 | The Research Foundation For The State University Of New York | Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction |
| EP3818051B1 (en) * | 2018-07-05 | 2022-08-03 | Bayer Aktiengesellschaft | Substituted thiophenecarboxamides and analogues as antibacterials agents |
| EP3949963A4 (en) * | 2019-04-02 | 2023-01-04 | Yonsei University, University-Industry Foundation(UIF). | NEW COMPOUND AND COMPOSITION FOR THE PREVENTION OR TREATMENT OF RESPIRATORY DISEASES COMPRISING THIS AS AN ACTIVE PRINCIPLE |
| CN110760597B (zh) * | 2019-11-22 | 2022-08-23 | 西北农林科技大学 | 一种检测黄牛ncstn基因拷贝数变异的方法及其应用 |
| WO2025117616A1 (en) * | 2023-11-27 | 2025-06-05 | Nikang Therapeutics, Inc. | Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and cyclin-dependent kinase 4 via ubiquitin proteasome pathway |
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| WO2005013914A2 (en) * | 2003-08-08 | 2005-02-17 | Vertex Pharmaceuticals Incorporated | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain |
| US20060014807A1 (en) * | 2004-07-19 | 2006-01-19 | Lin Leu-Fen H | Neuroprotective small organic molecules, compositions and uses related thereto |
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| US5734081A (en) * | 1994-08-05 | 1998-03-31 | Warner-Lambert Company | Arylthio compounds |
| AU2002221565A1 (en) * | 2000-12-08 | 2002-06-18 | Novo-Nordisk A/S | Trefoil factor 2 (tff2) peptides with moiety attached to asn15 |
| FI116940B (fi) * | 2001-07-20 | 2006-04-13 | Juvantia Pharma Ltd Oy | Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet |
| US7262185B2 (en) * | 2001-08-08 | 2007-08-28 | Takeda Chemical Industries Ltd. | Benzazepine derivative, process for producing the same, and use |
| FR2845382A1 (fr) * | 2002-10-02 | 2004-04-09 | Sanofi Synthelabo | Derives d'indazolecarboxamides, leur preparation et leur utilisation en therapeutique |
| US20050214751A1 (en) * | 2004-03-02 | 2005-09-29 | Proteologics, Inc. | Inhibition of viral maturation, methods and compositions related thereto |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005013914A2 (en) * | 2003-08-08 | 2005-02-17 | Vertex Pharmaceuticals Incorporated | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain |
| US20060014807A1 (en) * | 2004-07-19 | 2006-01-19 | Lin Leu-Fen H | Neuroprotective small organic molecules, compositions and uses related thereto |
Non-Patent Citations (4)
| Title |
|---|
| JPN6013000717; 'Ｓｙｎｔｈｅｓｉｓ ｏｆ ｓｏｍｅ ｎｅｗ ｈｅｔｅｒｏｂｉｃｙｃｌｉｃ ｃｏｍｐｏｕｎｄ ｂｅａｒｉｎｇ ｃｈｒｏｍｏｎ-３-ｙｌ ｍｏｉｅｔｙ ａｎｄ ｒｅｌａｔｅｄ ｃｏｍｐｏｕｎｄａ ａｓ ａ' Ｃｈｅｍｉｃａｌ ａｂｓｔｒａｃｔｓ Ｖｏｌ．１２７, 1997, ３４１７０ｈ，３４１７１ａ * |
| JPN6013000719; Ｒｅｇｉｓｔｒｙ Ｎｏ．３２６０２６-７５-９，Ｒｅｇｉｓｔｒｙ ［ｏｎｌｉｎｅ］； Ｒｅｔｒｉｅｖｅｄ ｆｒｏｍ ＳＴＮ , 20010307 * |
| JPN6013000721; Ｊｏｕｒｎａｌ ｏｆ Ｃｏｍｂｉｎａｔｏｒｉａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．８， Ｎｏ．３, 2006, ｐ．３２６-３３７ * |
| JPN6013000723; Ｓｕｌｆｕｒ Ｌｅｔｔｅｒｓ Ｖｏｌ．２４， Ｎｏ．４, 2001, ｐ．１５１-１７９ * |
Also Published As
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| EP2083826A2 (en) | 2009-08-05 |
| US8283355B2 (en) | 2012-10-09 |
| AU2007318922A1 (en) | 2008-05-15 |
| US20130131094A1 (en) | 2013-05-23 |
| WO2008056356A3 (en) | 2009-09-03 |
| CA2668859A1 (en) | 2008-05-15 |
| WO2008056356A2 (en) | 2008-05-15 |
| EP2083826A4 (en) | 2010-09-22 |
| AU2007318922C1 (en) | 2013-09-12 |
| US20100179178A1 (en) | 2010-07-15 |
| AU2007318922B2 (en) | 2013-01-10 |
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