JP2010508854A5 - - Google Patents
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- JP2010508854A5 JP2010508854A5 JP2009536475A JP2009536475A JP2010508854A5 JP 2010508854 A5 JP2010508854 A5 JP 2010508854A5 JP 2009536475 A JP2009536475 A JP 2009536475A JP 2009536475 A JP2009536475 A JP 2009536475A JP 2010508854 A5 JP2010508854 A5 JP 2010508854A5
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- JP
- Japan
- Prior art keywords
- cell population
- combination
- population
- hours
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000004027 cell Anatomy 0.000 claims description 100
- 210000000130 stem cell Anatomy 0.000 claims description 61
- 210000001519 tissue Anatomy 0.000 claims description 13
- 210000001185 bone marrow Anatomy 0.000 claims description 11
- 210000004700 fetal blood Anatomy 0.000 claims description 9
- 230000001400 myeloablative effect Effects 0.000 claims description 9
- 210000004369 blood Anatomy 0.000 claims description 7
- 239000008280 blood Substances 0.000 claims description 7
- 210000005259 peripheral blood Anatomy 0.000 claims description 6
- 239000011886 peripheral blood Substances 0.000 claims description 6
- 210000000440 neutrophil Anatomy 0.000 claims description 5
- 108020002663 Aldehyde Dehydrogenase Proteins 0.000 claims description 4
- 208000026350 Inborn Genetic disease Diseases 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 4
- 230000000157 blood function Effects 0.000 claims description 4
- 201000011510 cancer Diseases 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 208000016361 genetic disease Diseases 0.000 claims description 4
- 230000002708 enhancing effect Effects 0.000 claims description 3
- 230000003394 haemopoietic effect Effects 0.000 claims description 3
- 210000002997 osteoclast Anatomy 0.000 claims description 3
- 210000000988 bone and bone Anatomy 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 2
- 238000011275 oncology therapy Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 description 35
- 210000004504 adult stem cell Anatomy 0.000 description 6
- 230000003915 cell function Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- BHELIUBJHYAEDK-OAIUPTLZSA-N Aspoxicillin Chemical compound C1([C@H](C(=O)N[C@@H]2C(N3[C@H](C(C)(C)S[C@@H]32)C(O)=O)=O)NC(=O)[C@H](N)CC(=O)NC)=CC=C(O)C=C1 BHELIUBJHYAEDK-OAIUPTLZSA-N 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 210000001671 embryonic stem cell Anatomy 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 210000002536 stromal cell Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85754706P | 2006-11-08 | 2006-11-08 | |
| PCT/US2007/084037 WO2008060932A2 (en) | 2006-11-08 | 2007-11-08 | Methods for improved engraftment following stem cell transplantation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010508854A JP2010508854A (ja) | 2010-03-25 |
| JP2010508854A5 true JP2010508854A5 (enExample) | 2011-12-15 |
Family
ID=39327079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009536475A Pending JP2010508854A (ja) | 2006-11-08 | 2007-11-08 | 幹細胞移植の後の生着を改善するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100111905A1 (enExample) |
| EP (1) | EP2089042A2 (enExample) |
| JP (1) | JP2010508854A (enExample) |
| CA (1) | CA2668673A1 (enExample) |
| WO (1) | WO2008060932A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014189071A1 (ja) * | 2013-05-22 | 2014-11-27 | 独立行政法人国立精神・神経医療研究センター | 移植用幹細胞及びその製造方法 |
| CN118662615A (zh) | 2017-03-15 | 2024-09-20 | 浩康生物系统公司 | 用于造血干细胞移植的组合物和方法 |
| CN112669992B (zh) * | 2020-12-30 | 2024-06-11 | 中国人民解放军总医院 | 单倍体造血干细胞移植atg个体化用药量的计算方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
| CA2379683A1 (en) * | 1999-07-20 | 2001-01-25 | University Of Southern California | Identification of pluripotent pre-mesenchymal, pre-hematopoietic progenitor cell |
| US20020159984A1 (en) * | 1999-11-12 | 2002-10-31 | Quality Biological, Inc. | Cultivation of cells for long term engraftment |
| CA2438501C (en) * | 2001-02-14 | 2014-09-16 | Leo T. Furcht | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
| EP1718735A1 (en) * | 2004-02-11 | 2006-11-08 | Aldagen, Inc. | Stem cell populations and methods of use |
-
2007
- 2007-11-08 JP JP2009536475A patent/JP2010508854A/ja active Pending
- 2007-11-08 WO PCT/US2007/084037 patent/WO2008060932A2/en not_active Ceased
- 2007-11-08 EP EP07868696A patent/EP2089042A2/en not_active Withdrawn
- 2007-11-08 CA CA002668673A patent/CA2668673A1/en not_active Abandoned
- 2007-11-08 US US12/513,882 patent/US20100111905A1/en not_active Abandoned
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