JP2010508029A - 抗うつ薬による治療時に有害事象を発現する危険性のある患者の識別方法 - Google Patents

抗うつ薬による治療時に有害事象を発現する危険性のある患者の識別方法 Download PDF

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JP2010508029A
JP2010508029A JP2009534893A JP2009534893A JP2010508029A JP 2010508029 A JP2010508029 A JP 2010508029A JP 2009534893 A JP2009534893 A JP 2009534893A JP 2009534893 A JP2009534893 A JP 2009534893A JP 2010508029 A JP2010508029 A JP 2010508029A
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intron
polymorphism
seq
gene
comprises seq
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JP2010508029A5 (https=
Inventor
ジェイ． マクマホン、フランシス
イー． ラジェ、ゴンザロ
パドック、シルヴィア
ケー． マンジ、フセイニ
ジョン ラッシュ、エー．
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University of Texas System
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University of Texas System
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2009534893A 2006-10-27 2007-10-26 抗うつ薬による治療時に有害事象を発現する危険性のある患者の識別方法 Withdrawn JP2010508029A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85497806P 2006-10-27 2006-10-27
PCT/US2007/082683 WO2008052167A2 (en) 2006-10-27 2007-10-26 Methods to identify patients at risk of developing adverse events during treatment with antidepressant medication

Publications (2)

Publication Number Publication Date
JP2010508029A true JP2010508029A (ja) 2010-03-18
JP2010508029A5 JP2010508029A5 (https=) 2010-12-16

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ID=39276298

Family Applications (1)

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JP2009534893A Withdrawn JP2010508029A (ja) 2006-10-27 2007-10-26 抗うつ薬による治療時に有害事象を発現する危険性のある患者の識別方法

Country Status (5)

Country Link
US (2) US7906283B2 (https=)
EP (1) EP2087136A2 (https=)
JP (1) JP2010508029A (https=)
CA (1) CA2667812A1 (https=)
WO (1) WO2008052167A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2166112B1 (en) 2008-09-18 2013-06-05 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Means and methods for diagnosing predisposition for treatment emergent suicidal ideation
CA2736936A1 (en) 2008-09-18 2010-03-25 Andreas Menke Means and methods for diagnosing predisposition for treatment emergent suicidal ideation (tesi)
CA2918054C (en) * 2013-07-11 2022-12-13 The Johns Hopkins University A dna methylation and genotype specific biomarker of suicide attempt and/or suicide ideation
US11122997B2 (en) 2015-04-17 2021-09-21 Mayo Foundation For Medical Education And Research Modulating the aryl hydrocarbon receptor system to treat major depressive disorder
CA2891830A1 (en) 2015-05-15 2016-11-15 Centre For Addiction And Mental Health Genetic markers for suicide risk and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1410036A2 (en) 2001-01-19 2004-04-21 Mindsense Biosystems Ltd. Methods and compositions for diagnosing and treating a subject having depression
US7083921B2 (en) 2001-08-29 2006-08-01 The Board Of Trustees Of The Leland Stanford Junior University Method to determine the risk for side effects of an SSRI treatment in a person
JP5348840B2 (ja) 2003-02-20 2013-11-20 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 薬物を選択する方法
WO2004103394A2 (en) * 2003-05-15 2004-12-02 University Of Chicago Method and compositions for nerve regeneration
US20050069936A1 (en) 2003-09-26 2005-03-31 Cornelius Diamond Diagnostic markers of depression treatment and methods of use thereof
US20060160119A1 (en) 2005-01-14 2006-07-20 Barbara Turner Genetic screening for improving treatment of patients diagnosed with depression
US20080299125A1 (en) 2006-06-05 2008-12-04 Perlegen Sciences, Inc. Genetic basis of treatment response in depression patients

Also Published As

Publication number Publication date
WO2008052167A2 (en) 2008-05-02
EP2087136A2 (en) 2009-08-12
US20080102467A1 (en) 2008-05-01
US7906283B2 (en) 2011-03-15
CA2667812A1 (en) 2008-05-02
WO2008052167A3 (en) 2008-11-13
US20110118133A1 (en) 2011-05-19

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