JP2010505836A5 - - Google Patents
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- Publication number
- JP2010505836A5 JP2010505836A5 JP2009531440A JP2009531440A JP2010505836A5 JP 2010505836 A5 JP2010505836 A5 JP 2010505836A5 JP 2009531440 A JP2009531440 A JP 2009531440A JP 2009531440 A JP2009531440 A JP 2009531440A JP 2010505836 A5 JP2010505836 A5 JP 2010505836A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- disease
- radiation
- cancer
- renal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CC(C(*)C[C@](CC1)C[C@@](*)(C[C@](*)([C@]2[C@@](C)O3)C3=O)[C@]1([C@](C)C1)[C@@]21C=C[C@]1C(*)=CC(c2cccc(F)c2)=CC1)C(OCC(*)O)=O Chemical compound CC(C(*)C[C@](CC1)C[C@@](*)(C[C@](*)([C@]2[C@@](C)O3)C3=O)[C@]1([C@](C)C1)[C@@]21C=C[C@]1C(*)=CC(c2cccc(F)c2)=CC1)C(OCC(*)O)=O 0.000 description 3
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84928406P | 2006-10-04 | 2006-10-04 | |
| PCT/US2007/021259 WO2008060372A2 (en) | 2006-10-04 | 2007-10-02 | Thrombin receptor antagonists based on the modified tricyclic unit of himbacine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010505836A JP2010505836A (ja) | 2010-02-25 |
| JP2010505836A5 true JP2010505836A5 (https=) | 2010-04-22 |
Family
ID=39284222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009531440A Withdrawn JP2010505836A (ja) | 2006-10-04 | 2007-10-02 | ヒンバシンの修飾された三環単位に基づいたトロンビン受容体アンタゴニスト |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080085923A1 (https=) |
| EP (1) | EP2078012A2 (https=) |
| JP (1) | JP2010505836A (https=) |
| KR (1) | KR20090058583A (https=) |
| CN (1) | CN101553484A (https=) |
| AR (1) | AR063095A1 (https=) |
| AU (1) | AU2007320029A1 (https=) |
| CA (1) | CA2666903A1 (https=) |
| IL (1) | IL198011A0 (https=) |
| MX (1) | MX2009003758A (https=) |
| TW (1) | TW200823206A (https=) |
| WO (1) | WO2008060372A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8227412B2 (en) * | 2007-03-29 | 2012-07-24 | Tsopanoglou Nikos E | Bioactive parstatin peptides and methods of use |
| EP2438060B1 (en) * | 2009-06-04 | 2013-10-02 | Merck Sharp & Dohme Corp. | Active metabolite of a thrombin receptor antagonist |
| EP2488026A4 (en) * | 2009-10-02 | 2013-04-10 | Merck Sharp & Dohme | USE OF A PAR-1 ANTAGONIST IN COMBINATION WITH A P2Y12ADP RECEPTOR ANTAGONIST FOR INHIBITING THROMBOSE |
| CN105777681B (zh) * | 2014-12-17 | 2019-03-01 | 博瑞生物医药（苏州）股份有限公司 | 喜巴辛类似物及其中间体的制备方法 |
| WO2016114386A1 (ja) * | 2015-01-15 | 2016-07-21 | 国立研究開発法人国立精神・神経医療研究センター | 進行型免疫性脱髄疾患治療剤 |
| CN105985303B (zh) * | 2015-02-13 | 2020-08-14 | 上海彩迩文生化科技有限公司 | 抗凝血剂的制备方法、中间体及其制备方法 |
| CN106866450B (zh) * | 2017-01-13 | 2019-01-11 | 阜阳欣奕华材料科技有限公司 | 硫酸沃拉帕沙中间体的制备方法 |
| CN110483455A (zh) * | 2019-09-29 | 2019-11-22 | 天津力生制药股份有限公司 | 一种硫酸沃拉帕沙中间体醛基物的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063847A (en) * | 1997-11-25 | 2000-05-16 | Schering Corporation | Thrombin receptor antagonists |
| AU6690001A (en) * | 2000-06-15 | 2001-12-24 | Schering Corp | Thrombin receptor antagonists |
| KR100960170B1 (ko) * | 2001-10-18 | 2010-05-26 | 쉐링 코포레이션 | 트롬빈 수용체 길항제로서의 힘바신 동족체 |
| BRPI0309309B8 (pt) * | 2002-04-16 | 2021-05-25 | Merck Sharp & Dohme | antagonistas de receptor de trombina tricíclicos |
-
2007
- 2007-10-02 CA CA002666903A patent/CA2666903A1/en not_active Abandoned
- 2007-10-02 US US11/866,012 patent/US20080085923A1/en not_active Abandoned
- 2007-10-02 AR ARP070104357A patent/AR063095A1/es not_active Application Discontinuation
- 2007-10-02 MX MX2009003758A patent/MX2009003758A/es not_active Application Discontinuation
- 2007-10-02 KR KR1020097008460A patent/KR20090058583A/ko not_active Withdrawn
- 2007-10-02 WO PCT/US2007/021259 patent/WO2008060372A2/en not_active Ceased
- 2007-10-02 AU AU2007320029A patent/AU2007320029A1/en not_active Abandoned
- 2007-10-02 CN CNA2007800433580A patent/CN101553484A/zh active Pending
- 2007-10-02 JP JP2009531440A patent/JP2010505836A/ja not_active Withdrawn
- 2007-10-02 EP EP07867200A patent/EP2078012A2/en not_active Withdrawn
- 2007-10-03 TW TW096137099A patent/TW200823206A/zh unknown
-
2009
- 2009-04-05 IL IL198011A patent/IL198011A0/en unknown
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