JP2010504769A - マイボーム腺閉塞の溶解 - Google Patents
マイボーム腺閉塞の溶解 Download PDFInfo
- Publication number
- JP2010504769A JP2010504769A JP2009525537A JP2009525537A JP2010504769A JP 2010504769 A JP2010504769 A JP 2010504769A JP 2009525537 A JP2009525537 A JP 2009525537A JP 2009525537 A JP2009525537 A JP 2009525537A JP 2010504769 A JP2010504769 A JP 2010504769A
- Authority
- JP
- Japan
- Prior art keywords
- eyelid
- heating element
- heating
- heat
- heating unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010065062 Meibomian gland dysfunction Diseases 0.000 title claims description 26
- 230000008018 melting Effects 0.000 title 1
- 238000002844 melting Methods 0.000 title 1
- 238000010438 heat treatment Methods 0.000 claims abstract description 392
- 210000000744 eyelid Anatomy 0.000 claims abstract description 308
- 230000001105 regulatory effect Effects 0.000 claims abstract description 10
- 238000011282 treatment Methods 0.000 claims description 84
- 210000004175 meibomian gland Anatomy 0.000 claims description 66
- 238000000034 method Methods 0.000 claims description 61
- 230000001681 protective effect Effects 0.000 claims description 38
- 230000007246 mechanism Effects 0.000 claims description 37
- 230000028327 secretion Effects 0.000 claims description 33
- 210000001508 eye Anatomy 0.000 claims description 30
- 238000009413 insulation Methods 0.000 claims description 26
- 239000012530 fluid Substances 0.000 claims description 24
- 239000007787 solid Substances 0.000 claims description 17
- 239000000853 adhesive Substances 0.000 claims description 15
- 230000001070 adhesive effect Effects 0.000 claims description 15
- 238000012546 transfer Methods 0.000 claims description 15
- 239000011521 glass Substances 0.000 claims description 12
- 238000003860 storage Methods 0.000 claims description 11
- 229920001971 elastomer Polymers 0.000 claims description 10
- 239000012212 insulator Substances 0.000 claims description 10
- 239000005060 rubber Substances 0.000 claims description 10
- 239000002390 adhesive tape Substances 0.000 claims description 9
- 239000011810 insulating material Substances 0.000 claims description 8
- 210000003128 head Anatomy 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 5
- 239000000499 gel Substances 0.000 claims description 5
- 229910052710 silicon Inorganic materials 0.000 claims description 5
- 239000010703 silicon Substances 0.000 claims description 5
- 239000006071 cream Substances 0.000 claims description 4
- 230000002459 sustained effect Effects 0.000 claims description 4
- 239000006260 foam Substances 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 230000000670 limiting effect Effects 0.000 abstract description 7
- 210000004907 gland Anatomy 0.000 description 35
- 150000002632 lipids Chemical class 0.000 description 22
- 239000000463 material Substances 0.000 description 21
- 239000010408 film Substances 0.000 description 20
- 239000011888 foil Substances 0.000 description 19
- 208000003556 Dry Eye Syndromes Diseases 0.000 description 15
- 206010013774 Dry eye Diseases 0.000 description 15
- 230000006870 function Effects 0.000 description 13
- 230000003750 conditioning effect Effects 0.000 description 11
- 235000021251 pulses Nutrition 0.000 description 11
- 230000001225 therapeutic effect Effects 0.000 description 11
- 230000009286 beneficial effect Effects 0.000 description 10
- 238000013461 design Methods 0.000 description 10
- 238000010586 diagram Methods 0.000 description 10
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 9
- 244000046052 Phaseolus vulgaris Species 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 9
- 239000006196 drop Substances 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 230000007423 decrease Effects 0.000 description 7
- 229920002379 silicone rubber Polymers 0.000 description 7
- 208000035475 disorder Diseases 0.000 description 5
- 230000004064 dysfunction Effects 0.000 description 5
- 230000000762 glandular Effects 0.000 description 5
- 230000033001 locomotion Effects 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 230000010349 pulsation Effects 0.000 description 5
- 210000002374 sebum Anatomy 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 5
- 238000002560 therapeutic procedure Methods 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 230000033228 biological regulation Effects 0.000 description 4
- 208000010217 blepharitis Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 210000005252 bulbus oculi Anatomy 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000001704 evaporation Methods 0.000 description 4
- 230000008020 evaporation Effects 0.000 description 4
- 230000004054 inflammatory process Effects 0.000 description 4
- 230000000414 obstructive effect Effects 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 239000004945 silicone rubber Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 239000003098 androgen Substances 0.000 description 3
- 230000004397 blinking Effects 0.000 description 3
- 238000009530 blood pressure measurement Methods 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000004590 computer program Methods 0.000 description 3
- 239000004020 conductor Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000029142 excretion Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 201000003265 lymphadenitis Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 230000009182 swimming Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000010409 thin film Substances 0.000 description 3
- 241000282412 Homo Species 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 208000012868 Overgrowth Diseases 0.000 description 2
- 239000004098 Tetracycline Substances 0.000 description 2
- 229940030486 androgens Drugs 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000000981 epithelium Anatomy 0.000 description 2
- 239000000262 estrogen Substances 0.000 description 2
- 229940011871 estrogen Drugs 0.000 description 2
- 239000003889 eye drop Substances 0.000 description 2
- 229940012356 eye drops Drugs 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000003054 hormonal effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000012774 insulation material Substances 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 210000004561 lacrimal apparatus Anatomy 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 210000001732 sebaceous gland Anatomy 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- 235000019364 tetracycline Nutrition 0.000 description 2
- 150000003522 tetracyclines Chemical class 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- MJYQFWSXKFLTAY-OVEQLNGDSA-N (2r,3r)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol;(2r,3r,4s,5s,6r)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O.C1=C(O)C(OC)=CC(C[C@@H](CO)[C@H](CO)CC=2C=C(OC)C(O)=CC=2)=C1 MJYQFWSXKFLTAY-OVEQLNGDSA-N 0.000 description 1
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010057385 Eyelid irritation Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 102000015728 Mucins Human genes 0.000 description 1
- 108010063954 Mucins Proteins 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000295644 Staphylococcaceae Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 description 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000005081 epithelial layer Anatomy 0.000 description 1
- 230000003090 exacerbative effect Effects 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 235000004426 flaxseed Nutrition 0.000 description 1
- 239000006261 foam material Substances 0.000 description 1
- 229920001821 foam rubber Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000008570 general process Effects 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 201000010666 keratoconjunctivitis Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 230000009245 menopause Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940051875 mucins Drugs 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920001084 poly(chloroprene) Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000011253 protective coating Substances 0.000 description 1
- 230000001185 psoriatic effect Effects 0.000 description 1
- 230000008844 regulatory mechanism Effects 0.000 description 1
- 238000003303 reheating Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 229940040944 tetracyclines Drugs 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- 239000002470 thermal conductor Substances 0.000 description 1
- 239000002937 thermal insulation foam Substances 0.000 description 1
- 238000000015 thermotherapy Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 229940125379 topical corticosteroid Drugs 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000011277 treatment modality Methods 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
Images
Landscapes
- Percussion Or Vibration Massage (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/541,308 US20070060988A1 (en) | 2005-07-18 | 2006-09-29 | Melting meibomian gland obstructions |
| PCT/US2007/000508 WO2008039221A1 (en) | 2006-08-21 | 2007-01-09 | Providing gas and vapor to a patient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010504769A true JP2010504769A (ja) | 2010-02-18 |
| JP2010504769A5 JP2010504769A5 (enExample) | 2010-04-02 |
Family
ID=42026069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009525537A Pending JP2010504769A (ja) | 2006-09-29 | 2007-01-09 | マイボーム腺閉塞の溶解 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2010504769A (enExample) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011188958A (ja) * | 2010-03-12 | 2011-09-29 | Kanazawa Univ | シェーグレン症候群及びドライマウスの治療器並びにドライアイの治療器 |
| JP2011244923A (ja) * | 2010-05-25 | 2011-12-08 | Panasonic Electric Works Co Ltd | 目元用美容器具 |
| JP2011244921A (ja) * | 2010-05-25 | 2011-12-08 | Panasonic Electric Works Co Ltd | 目元用美容器具 |
| JP2014514038A (ja) * | 2011-03-15 | 2014-06-19 | ポリフォトニクス リミテッド | カートリッジ、医療用装置及びその使用方法 |
| JP2015503417A (ja) * | 2012-01-04 | 2015-02-02 | サイト サイエンシーズ, インコーポレイテッド | ドライアイ治療システム |
| US10772758B2 (en) | 2012-01-04 | 2020-09-15 | Sight Sciences, Inc. | Dry eye treatment apparatus and methods |
| US10973680B2 (en) | 2012-01-04 | 2021-04-13 | Sight Sciences, Inc. | Controller for dry eye treatment systems |
| US11285040B2 (en) | 2012-01-04 | 2022-03-29 | Sight Sciences, Inc. | Combination treatment systems |
| JP2022537115A (ja) * | 2019-06-06 | 2022-08-24 | ノヴォクセル リミテッド | 組織応力を使用して眼瞼炎を治療するためのシステム及び方法 |
| US12263115B2 (en) | 2018-09-11 | 2025-04-01 | Sight Sciences, Inc. | Forceps treatment systems |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001276113A (ja) * | 2000-03-29 | 2001-10-09 | Toshihiro Kuribayashi | 眼性疲労及び視力低下防止器具 |
| JP2006198249A (ja) * | 2005-01-21 | 2006-08-03 | Rohto Pharmaceut Co Ltd | ドライアイ治療用具 |
-
2007
- 2007-01-09 JP JP2009525537A patent/JP2010504769A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001276113A (ja) * | 2000-03-29 | 2001-10-09 | Toshihiro Kuribayashi | 眼性疲労及び視力低下防止器具 |
| JP2006198249A (ja) * | 2005-01-21 | 2006-08-03 | Rohto Pharmaceut Co Ltd | ドライアイ治療用具 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6013003409; E Goto, et al.: 'Treatment of non-inflamed obstructive meibomian gland dysfunction by an infrared warm compression de' British Journal of Ophthalmology Vol. 86, 2002, p. 1403-1407 * |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011188958A (ja) * | 2010-03-12 | 2011-09-29 | Kanazawa Univ | シェーグレン症候群及びドライマウスの治療器並びにドライアイの治療器 |
| JP2011244923A (ja) * | 2010-05-25 | 2011-12-08 | Panasonic Electric Works Co Ltd | 目元用美容器具 |
| JP2011244921A (ja) * | 2010-05-25 | 2011-12-08 | Panasonic Electric Works Co Ltd | 目元用美容器具 |
| JP2014514038A (ja) * | 2011-03-15 | 2014-06-19 | ポリフォトニクス リミテッド | カートリッジ、医療用装置及びその使用方法 |
| US11285040B2 (en) | 2012-01-04 | 2022-03-29 | Sight Sciences, Inc. | Combination treatment systems |
| US12263116B2 (en) | 2012-01-04 | 2025-04-01 | Sight Sciences, Inc. | Dry eye treatment systems |
| JP2019034176A (ja) * | 2012-01-04 | 2019-03-07 | サイト サイエンシーズ, インコーポレイテッド | ドライアイ治療システム |
| US10772758B2 (en) | 2012-01-04 | 2020-09-15 | Sight Sciences, Inc. | Dry eye treatment apparatus and methods |
| US10925765B2 (en) | 2012-01-04 | 2021-02-23 | Sight Sciences, Inc. | Dry eye treatment systems |
| US10973680B2 (en) | 2012-01-04 | 2021-04-13 | Sight Sciences, Inc. | Controller for dry eye treatment systems |
| JP2015503417A (ja) * | 2012-01-04 | 2015-02-02 | サイト サイエンシーズ, インコーポレイテッド | ドライアイ治療システム |
| US12336930B2 (en) | 2012-01-04 | 2025-06-24 | Sight Sciences, Inc. | Dry eye treatment apparatus and methods |
| JP2022140786A (ja) * | 2012-01-04 | 2022-09-27 | サイト サイエンシーズ, インコーポレイテッド | ドライアイ治療システム |
| US10052226B2 (en) | 2012-01-04 | 2018-08-21 | Sight Sciences, Inc. | Dry eye treatment systems |
| JP7625558B2 (ja) | 2012-01-04 | 2025-02-03 | サイト サイエンシーズ, インコーポレイテッド | ドライアイ治療システム |
| US12257181B2 (en) | 2012-01-04 | 2025-03-25 | Sight Sciences, Inc. | Controller for dry eye treatment systems |
| US12263115B2 (en) | 2018-09-11 | 2025-04-01 | Sight Sciences, Inc. | Forceps treatment systems |
| JP7496557B2 (ja) | 2019-06-06 | 2024-06-07 | ノヴォクセル リミテッド | 組織応力を使用して眼瞼炎を治療するためのシステム及び方法 |
| US12285362B2 (en) | 2019-06-06 | 2025-04-29 | Novoxel Ltd | System and method for treating blepharitis using tissue stressing |
| JP2022537115A (ja) * | 2019-06-06 | 2022-08-24 | ノヴォクセル リミテッド | 組織応力を使用して眼瞼炎を治療するためのシステム及び方法 |
| KR102886697B1 (ko) | 2019-06-06 | 2025-11-17 | 노보셀 리미티드 | 조직 응력화를 이용하여 안건염을 치료하기 위한 시스템 및 방법 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10940074B2 (en) | Melting meibomian gland obstructions | |
| EP2053997A1 (en) | Melting meibomian gland obstructions | |
| JP2010504769A (ja) | マイボーム腺閉塞の溶解 | |
| US20210205131A1 (en) | Methods and apparatuses for treatment of meibomian gland dysfunction | |
| US20230301825A1 (en) | Eye thermal compress | |
| US8128674B2 (en) | System for outer eyelid heat and pressure treatment for treating meibomian gland dysfunction | |
| US7976573B2 (en) | Inner eyelid heat and pressure treatment for treating meibomian gland dysfunction | |
| US7981147B2 (en) | Outer eyelid heat and pressure treatment for treating meibomian gland dysfunction | |
| US9913678B2 (en) | Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma | |
| US7981146B2 (en) | Inner eyelid treatment for treating meibomian gland dysfunction | |
| US9314369B2 (en) | System for inner eyelid treatment of meibomian gland dysfunction | |
| US8137390B2 (en) | System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction | |
| US8128673B2 (en) | System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction | |
| JP5406728B2 (ja) | マイボーム腺機能不全を治療するための熱治療のための方法、システム、および装置 | |
| US8007524B2 (en) | Heat treatment and heat loss reduction for treating meibomian gland dysfunction | |
| US20170299567A1 (en) | Methods and systems for treating meibomian gland dysfunction using radio-frequency energy | |
| WO2008039221A1 (en) | Providing gas and vapor to a patient |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100108 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20100108 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20111228 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120110 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20120404 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20120411 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120710 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130129 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20130315 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130425 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20130507 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20140107 |