JP2010502192A5 - - Google Patents
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- Publication number
- JP2010502192A5 JP2010502192A5 JP2009526917A JP2009526917A JP2010502192A5 JP 2010502192 A5 JP2010502192 A5 JP 2010502192A5 JP 2009526917 A JP2009526917 A JP 2009526917A JP 2009526917 A JP2009526917 A JP 2009526917A JP 2010502192 A5 JP2010502192 A5 JP 2010502192A5
- Authority
- JP
- Japan
- Prior art keywords
- boris
- expression
- seq
- isoform
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101000894428 Homo sapiens Transcriptional repressor CTCFL Proteins 0.000 claims description 74
- 102100021393 Transcriptional repressor CTCFL Human genes 0.000 claims description 73
- 108010029485 Protein Isoforms Proteins 0.000 claims description 45
- 102000001708 Protein Isoforms Human genes 0.000 claims description 45
- 229920001184 polypeptide Polymers 0.000 claims description 25
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 25
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 25
- 201000010099 disease Diseases 0.000 claims description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 19
- 108020004999 messenger RNA Proteins 0.000 claims description 19
- 241000124008 Mammalia Species 0.000 claims description 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 17
- 206010028980 Neoplasm Diseases 0.000 claims description 10
- 201000011510 cancer Diseases 0.000 claims description 10
- 239000002773 nucleotide Substances 0.000 claims description 9
- 125000003729 nucleotide group Chemical group 0.000 claims description 9
- 150000007523 nucleic acids Chemical class 0.000 claims description 8
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 3
- 238000000034 method Methods 0.000 claims 16
- 239000000523 sample Substances 0.000 claims 11
- 230000002159 abnormal effect Effects 0.000 claims 8
- 108020004459 Small interfering RNA Proteins 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 239000004055 small Interfering RNA Substances 0.000 claims 6
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 2
- 230000001594 aberrant effect Effects 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 238000003757 reverse transcription PCR Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84134206P | 2006-08-31 | 2006-08-31 | |
| PCT/US2007/077281 WO2008028066A2 (en) | 2006-08-31 | 2007-08-30 | Boris isoforms and methods of detecting and treating disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010502192A JP2010502192A (ja) | 2010-01-28 |
| JP2010502192A5 true JP2010502192A5 (cg-RX-API-DMAC7.html) | 2010-10-14 |
Family
ID=38846916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526917A Pending JP2010502192A (ja) | 2006-08-31 | 2007-08-30 | Ｂｏｒｉｓアイソフォーム並びに疾患を検出及び治療する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8206933B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2057469A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010502192A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007289149B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2662012C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008028066A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7998486B2 (en) * | 2006-10-25 | 2011-08-16 | Newlink Genetics Corporation | Enhanced immunogenicity of tumor associated antigens by addition of alphaGal epitopes |
| CN101821410B (zh) * | 2007-08-10 | 2016-01-27 | 温德维亚集团公司 | 印迹位点调节物兄弟(boris)的基因沉默 |
| EP3199627B1 (en) * | 2014-09-24 | 2021-04-07 | Sapporo Medical University | Tumor antigen peptides |
| US10415094B2 (en) | 2016-10-06 | 2019-09-17 | HelicalHelp LLC | Risk stratification method for a patient having a polymorphism |
| BR112021013197A2 (pt) | 2019-01-24 | 2021-09-28 | Lumus Ltd. | Sistema óptico |
| TWI897971B (zh) | 2020-06-01 | 2025-09-21 | 以色列商魯姆斯有限公司 | 用於近眼顯示器的虛擬影像遞送系統 |
| CN114514460A (zh) | 2020-08-23 | 2022-05-17 | 鲁姆斯有限公司 | 减少波导的闪烁和重影的用于图像的二维扩展的光学系统 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003072799A2 (en) | 2002-02-22 | 2003-09-04 | The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Brother of the regulator of imprinted sites (boris) |
| WO2006034335A2 (en) * | 2004-09-21 | 2006-03-30 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Method of detecting cancer based on immune reaction to boris |
-
2007
- 2007-08-30 CA CA2662012A patent/CA2662012C/en active Active
- 2007-08-30 US US12/439,063 patent/US8206933B2/en active Active
- 2007-08-30 JP JP2009526917A patent/JP2010502192A/ja active Pending
- 2007-08-30 WO PCT/US2007/077281 patent/WO2008028066A2/en not_active Ceased
- 2007-08-30 AU AU2007289149A patent/AU2007289149B2/en active Active
- 2007-08-30 EP EP07841646A patent/EP2057469A2/en not_active Withdrawn
-
2012
- 2012-05-23 US US13/478,779 patent/US8440415B2/en active Active
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