JP2010501074A - グリカンのデータマイニングシステム - Google Patents

グリカンのデータマイニングシステム Download PDF

Info

Publication number
JP2010501074A
JP2010501074A JP2009524675A JP2009524675A JP2010501074A JP 2010501074 A JP2010501074 A JP 2010501074A JP 2009524675 A JP2009524675 A JP 2009524675A JP 2009524675 A JP2009524675 A JP 2009524675A JP 2010501074 A JP2010501074 A JP 2010501074A
Authority
JP
Japan
Prior art keywords
binding
glycan
glycans
type
sialic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009524675A
Other languages
English (en)
Japanese (ja)
Inventor
ラム サシセカラン，
エス． ラグラム，
マーデバン ベンカタラマン，
サブラマニアン カウンディンヤ，
ラウル ラマン，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of JP2010501074A publication Critical patent/JP2010501074A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
JP2009524675A 2006-08-14 2007-08-14 グリカンのデータマイニングシステム Pending JP2010501074A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83786806P 2006-08-14 2006-08-14
US83786906P 2006-08-14 2006-08-14
PCT/US2007/018103 WO2008021415A2 (en) 2006-08-14 2007-08-14 Glycan data mining system

Publications (1)

Publication Number Publication Date
JP2010501074A true JP2010501074A (ja) 2010-01-14

Family

ID=39082721

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009524675A Pending JP2010501074A (ja) 2006-08-14 2007-08-14 グリカンのデータマイニングシステム
JP2009524682A Pending JP2010500880A (ja) 2006-08-14 2007-08-14 ヘマグルチニンポリペプチド、ならびにヘマグルチニンポリペプチドに関連する試薬および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009524682A Pending JP2010500880A (ja) 2006-08-14 2007-08-14 ヘマグルチニンポリペプチド、ならびにヘマグルチニンポリペプチドに関連する試薬および方法

Country Status (8)

Country Link
US (3) US20080241918A1 (https=)
EP (2) EP2049569A4 (https=)
JP (2) JP2010501074A (https=)
KR (1) KR20090050056A (https=)
AU (2) AU2007332987B2 (https=)
CA (2) CA2660128A1 (https=)
IL (1) IL196738A0 (https=)
WO (2) WO2008073161A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541528A (ja) * 2010-09-21 2013-11-14 マサチューセッツ インスティテュート オブ テクノロジー ヒト適応ｈａポリペプチド、ワクチン、およびインフルエンザの処置

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2027146B1 (en) * 2006-05-30 2012-10-03 Bogoch, Samuel, Dr. Replikin peptides and uses thereof
EP2092059A4 (en) * 2006-10-24 2012-03-28 Bogoch Samuel METHOD FOR FORECASTING INFLUENZA EXCESSIONS BY CORRELATION OF AN INCREASED REPLICINE MIRROR IN WHITE SPOT AND / OR TAURA VIRUSES IN CRABES
EP2126140A4 (en) * 2007-01-18 2012-03-28 Samuel Bogoch METHOD FOR DETERMINING THE MORTALITY OF PATHOGENS AND MALIGNOMAS WITH REPLICINE TIPS
CA2689181A1 (en) * 2007-05-30 2008-12-24 Samuel Bogoch Synthetic replikin peptides against pathogenic infection of invertebrates in aquaculture
CA2711334A1 (en) * 2008-01-03 2009-07-16 Massachusetts Institute Of Technology Hemagglutinin polypeptides, and reagents and methods relating thereto
CA2711330A1 (en) 2008-01-03 2009-07-16 Massachusetts Institute Of Technology Decoy influenza therapies
US20090269367A1 (en) * 2008-04-23 2009-10-29 Samuel Bogoch Methods and compounds for mitigating pathogenic outbreaks using replikin count cycles
US20100144589A1 (en) * 2008-08-08 2010-06-10 Samuel Bogoch Methods of predicting cancer lethality using replikin counts
US9233148B2 (en) * 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
JP5396111B2 (ja) * 2009-03-12 2014-01-22 学校法人慶應義塾 インフルエンザ治療／予防薬
CA2756206C (en) 2009-03-27 2025-05-13 Academia Sinica METHODS AND COMPOSITIONS FOR IMMUNIZATION AGAINST A VIRUS
NZ595812A (en) * 2009-04-23 2013-09-27 Samuel Bogoch Replikin-sequences for preventing/treating influenza and determining infectivity/lethality
US9278998B2 (en) 2009-07-02 2016-03-08 Massachusetts Institute Of Technology Compositions and methods for diagnosing and/or treating influenza infection
KR101346197B1 (ko) * 2009-07-17 2014-02-06 한림대학교 산학협력단 리포좀에 포집된 올리고뉴클레오타이드 및 에피토프를 포함하는 면역증강용 조성물
US20110091493A1 (en) * 2009-10-16 2011-04-21 Northwestern University Vaccine compositions and uses thereof
WO2011094445A1 (en) 2010-01-27 2011-08-04 Massachusetts Institute Of Technology Engineered polypeptide agents for targeted broad spectrum influenza neutralization
BR112013007946B1 (pt) * 2010-10-04 2022-07-12 Massachusetts Institute Of Technology Composições farmacêuticas e imunogênicas compreendendo polipeptídeos de hemaglutinina
TWI537385B (zh) 2010-11-04 2016-06-11 中央研究院 產生具簡單醣基化之表面蛋白質之病毒顆粒的方法
EP2652496B1 (en) 2010-12-13 2018-01-17 The University of Utah Research Foundation Vaccine antigens that direct immunity to conserved epitopes
CA2842345A1 (en) 2011-07-20 2013-01-24 Samuel Bogoch Peptides shared among lethal cancers and therapeutic compositions comprising said peptides
EP2814837B1 (en) 2012-02-13 2017-11-29 University of Pittsburgh - Of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for human and avian h5n1 influenza
WO2013130017A1 (en) * 2012-02-29 2013-09-06 Agency For Science, Technology And Research Modulating the interaction between zo-2/tjp2 and a snail zinc finger transcription factor family member
HK1207970A1 (en) 2012-05-10 2016-02-19 Massachusetts Institute Of Technology Agents for influenza neutralization
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
PL2876447T3 (pl) 2012-07-19 2020-05-18 Toray Industries, Inc. Sposób wykrywania nowotworu
US20140286981A1 (en) 2013-03-14 2014-09-25 Wisconsin Alumni Research Foundation Broadly reactive mosaic peptide for influenza vaccine
US10526375B2 (en) 2013-06-05 2020-01-07 Massachusetts Institute Of Technology Human Adaptation of H7 HA
US10732180B2 (en) 2014-06-04 2020-08-04 Indevr, Inc. Universal capture array for multiplexed subtype-specific quantification and stability determination of influenza proteins
JP6964581B2 (ja) * 2015-08-20 2021-11-10 シーラス ロジック インターナショナル セミコンダクター リミテッド 固定応答フィルタによって部分的に提供されるフィードバック応答を有するフィードバック適応雑音消去（ａｎｃ）コントローラおよび方法
WO2017083627A1 (en) 2015-11-13 2017-05-18 Visterra, Inc. Compositions and methods for treating and preventing influenza
CN109195629A (zh) 2016-02-24 2019-01-11 威特拉公司 流行性感冒抗体分子制剂
MX2020004151A (es) 2017-10-30 2020-08-13 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos.
CN113924147A (zh) 2019-03-25 2022-01-11 威特拉公司 用于治疗和预防流感的组合物和方法
CN115551885A (zh) 2019-12-11 2022-12-30 威特拉公司 用于治疗和预防流感的组合物和方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005088310A2 (en) * 2004-03-05 2005-09-22 The Scripps Research Institute High throughput glycan microarrays

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) * 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4270537A (en) * 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4596556A (en) * 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4886499A (en) * 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) * 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4790824A (en) * 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) * 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4940460A (en) * 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US5339163A (en) * 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) * 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) * 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5190521A (en) * 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
JPH06247995A (ja) * 1991-06-24 1994-09-06 Asahi Chem Ind Co Ltd 新規なシアリル（α２−６）ラクトテトラオシルセラミド
GB9118204D0 (en) * 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) * 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) * 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) * 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) * 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) * 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
WO1995024176A1 (en) * 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) * 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5893397A (en) * 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US5993412A (en) * 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
CA2365575A1 (en) * 1999-03-31 2000-10-12 Otsuka Pharmaceutical Co., Ltd. Influenza virus hemagglutinin-binding peptides
WO2003074570A1 (fr) * 2002-03-04 2003-09-12 Japan Science And Technology Agency Nouvelles molecules de sialo-sucre ramifiees et agents antiviraux les utilisant
AU2003265523A1 (en) * 2002-08-20 2004-03-11 Genitrix, Llc Lectin compositions and methods for modulating an immune response to an antigen
US20050221337A1 (en) * 2003-10-02 2005-10-06 Massachusetts Institute Of Technology Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
AU2005303817B8 (en) * 2004-11-11 2010-09-30 Abbott Biologicals B.V. Defective influenza virus particles
US7959929B2 (en) * 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US7871626B2 (en) * 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
US20090099036A1 (en) * 2006-04-18 2009-04-16 The Regents Of The University Of Michigan Methods and compositions for screening glycan structures
US20080220988A1 (en) * 2007-03-07 2008-09-11 Ada Technologies, Inc. Preparing carbohydrate microarrays and conjugated nanoparticles
US20110257032A1 (en) * 2010-04-16 2011-10-20 Massachusetts Institute Of Technology Modular glycan arrays

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005088310A2 (en) * 2004-03-05 2005-09-22 The Scripps Research Institute High throughput glycan microarrays

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541528A (ja) * 2010-09-21 2013-11-14 マサチューセッツ インスティテュート オブ テクノロジー ヒト適応ｈａポリペプチド、ワクチン、およびインフルエンザの処置
US9745352B2 (en) 2010-09-21 2017-08-29 Massachusetts Institute Of Technology Influenza treatment and/or characterization, human-adapted HA polypeptides; vaccines

Also Published As

Publication number Publication date
WO2008021415A3 (en) 2008-11-20
EP2049569A4 (en) 2010-11-24
EP2052340A4 (en) 2010-11-17
CA2660128A1 (en) 2008-02-21
WO2008021415A9 (en) 2008-07-10
IL196738A0 (en) 2011-08-01
AU2007332987B2 (en) 2013-01-10
US20100125043A1 (en) 2010-05-20
WO2008021415A2 (en) 2008-02-21
AU2007332987A1 (en) 2008-06-19
WO2008073161A3 (en) 2009-05-22
WO2008073161A9 (en) 2008-07-31
AU2007284496A1 (en) 2008-02-21
CA2660038A1 (en) 2008-06-19
US20100061990A1 (en) 2010-03-11
KR20090050056A (ko) 2009-05-19
EP2052340A2 (en) 2009-04-29
JP2010500880A (ja) 2010-01-14
US20080241918A1 (en) 2008-10-02
WO2008073161A2 (en) 2008-06-19
EP2049569A2 (en) 2009-04-22

Similar Documents

Publication Publication Date Title
JP2010501074A (ja) グリカンのデータマイニングシステム
Zupancic et al. Glycan microarray analysis of Candida glabrata adhesin ligand specificity
US20090081193A1 (en) Hemagglutinin polypeptides, and reagents and methods relating thereto
Kim et al. GlycoGrip: cell surface-inspired universal sensor for betacoronaviruses
JP2010500880A5 (https=)
EP2448596B1 (en) Compositions and methods for diagnosing and/or treating influenza infection
JP4696100B2 (ja) 炭水化物ポリマーの比較分析のための方法
US20090269342A1 (en) Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto
JP2010181411A (ja) 多糖類の構造および配列決定
Gulati et al. Glycan array analysis of influenza H1N1 binding and release
Jayaraman et al. Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors
JP2016094484A (ja) ヒト適応ｈａポリペプチド、ワクチン、およびインフルエンザの処置
Yang et al. LectoScape: a highly multiplexed imaging platform for glycome analysis and biomedical diagnosis
CN101501696A (zh) 聚糖数据挖掘系统
CA2711334A1 (en) Hemagglutinin polypeptides, and reagents and methods relating thereto
WO2019147891A1 (en) Compositions and methods for determining avian influenza virus susceptabilty
US20110257032A1 (en) Modular glycan arrays
Singh et al. Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre
Spruit et al. N-glycolylneuraminic acid binding of avian H7 influenza A viruses

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100810

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110728

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20111215

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111222

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120607