JP2010500038A - 血液白血球中の遺伝子発現サインが、急性感染の差次的診断を可能にする - Google Patents

血液白血球中の遺伝子発現サインが、急性感染の差次的診断を可能にする Download PDF

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Publication number
JP2010500038A
JP2010500038A JP2009524013A JP2009524013A JP2010500038A JP 2010500038 A JP2010500038 A JP 2010500038A JP 2009524013 A JP2009524013 A JP 2009524013A JP 2009524013 A JP2009524013 A JP 2009524013A JP 2010500038 A JP2010500038 A JP 2010500038A
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genes
infection
expression
patients
expression level
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Japanese (ja)
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ジャック エフ． バンチェレイア
アンナ カロリーナ パルッカ
オクタビオ ラミロ
ダミアン ショサベル
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Baylor Research Institute
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Baylor Research Institute
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2009524013A 2006-08-11 2007-08-10 血液白血球中の遺伝子発現サインが、急性感染の差次的診断を可能にする Ceased JP2010500038A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83714806P 2006-08-11 2006-08-11
PCT/US2007/075713 WO2008024642A2 (en) 2006-08-11 2007-08-10 Gene expression signatures in blood leukocytes permit differential diagnosis of acute infections

Related Child Applications (1)

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JP2012255823A Division JP2013066474A (ja) 2006-08-11 2012-11-22 血液白血球中の遺伝子発現サインが、急性感染の差次的診断を可能にする

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JP2010500038A true JP2010500038A (ja) 2010-01-07

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JP2009524013A Ceased JP2010500038A (ja) 2006-08-11 2007-08-10 血液白血球中の遺伝子発現サインが、急性感染の差次的診断を可能にする
JP2012255823A Pending JP2013066474A (ja) 2006-08-11 2012-11-22 血液白血球中の遺伝子発現サインが、急性感染の差次的診断を可能にする

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Country Status (8)

Country Link
US (1) US20080171323A1 (enExample)
EP (1) EP2057286A4 (enExample)
JP (2) JP2010500038A (enExample)
CN (1) CN101541976A (enExample)
AU (1) AU2007286915B2 (enExample)
CA (1) CA2695935A1 (enExample)
SG (1) SG177956A1 (enExample)
WO (1) WO2008024642A2 (enExample)

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JP2015530868A (ja) * 2012-07-10 2015-10-29 ネピアン ブルー マウンテンズ ローカル ヘルス ディストリクト インフルエンザにおけるリスクの階層化
JP2017528129A (ja) * 2014-08-22 2017-09-28 インスティチュート・オブ・バイオフィジックス，チャイニーズ・アカデミー・オブ・サイエンシズ 異常なレベル及び／又は活性のｉｆｐ３５ファミリーのタンパク質に関連する疾患又は障害を治療及び／又は予防するための方法及び組成物

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US10013641B2 (en) * 2009-09-28 2018-07-03 Oracle International Corporation Interactive dendrogram controls
EP2561363B1 (en) 2010-04-21 2021-07-14 Memed Diagnostics, Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
EP3882633A1 (en) 2012-02-09 2021-09-22 MeMed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
KR101459186B1 (ko) 2012-04-26 2014-11-07 울산대학교 산학협력단 지속적 황색포도알균 균혈증의 조기 진단용 조성물 및 조기 진단방법
WO2015048098A1 (en) 2013-09-24 2015-04-02 Washington University Diagnostic methods for infectious disease using endogenous gene expression
WO2015103664A1 (en) * 2014-01-09 2015-07-16 Nepean Blue Montains Local Health District Risk stratification in influenza
CN111624346A (zh) 2014-08-14 2020-09-04 米密德诊断学有限公司 用于预测及/或决定预后的套组
US20170234873A1 (en) 2014-10-14 2017-08-17 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
CA2968650A1 (en) 2014-12-11 2016-06-16 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
CN105316404B (zh) * 2015-02-27 2017-02-22 中南大学湘雅二医院 系统性红斑狼疮生物标志物及其诊断试剂盒
CN120966978A (zh) * 2015-07-01 2025-11-18 杜克大学 诊断和治疗急性呼吸系统感染的方法
WO2017004448A1 (en) * 2015-07-02 2017-01-05 Indevr, Inc. Methods of processing and classifying microarray data for the detection and characterization of pathogens
KR20170027258A (ko) * 2015-09-01 2017-03-09 제이더블유바이오사이언스 주식회사 트립토파닐 티알엔에이 합성효소를 이용한 패혈증의 진단용 조성물과 진단 마커 검출 방법
CN108699583B (zh) * 2016-03-03 2022-11-01 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
US12338497B2 (en) 2016-03-03 2025-06-24 Memed Diagnostics Ltd. Analyzing RNA for diagnosing infection type
EP3482201B1 (en) 2016-07-10 2022-12-14 Memed Diagnostics Ltd. Early diagnosis of infections
WO2018011795A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
PT3489686T (pt) * 2017-11-22 2021-02-12 Dewact Labs GmbH Método e dispositivo para discriminar entre infecções virais e bacterianas
CN108846258B (zh) * 2018-06-08 2021-05-18 中国人民解放军军事科学院军事医学研究院 一种自动检测分节段rna病毒重配的方法
CN112080559B (zh) * 2019-06-14 2023-09-01 复旦大学附属华山医院 Ppp1cb基因snp位点在制备检测寻常型银屑病易感性产品中的应用
CN110656177A (zh) * 2019-10-15 2020-01-07 合肥艾迪康医学检验实验室有限公司 用于检测af1q基因相对表达量的引物、探针及方法和试剂盒
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Cited By (3)

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Publication number Priority date Publication date Assignee Title
JP2015530868A (ja) * 2012-07-10 2015-10-29 ネピアン ブルー マウンテンズ ローカル ヘルス ディストリクト インフルエンザにおけるリスクの階層化
JP2017528129A (ja) * 2014-08-22 2017-09-28 インスティチュート・オブ・バイオフィジックス，チャイニーズ・アカデミー・オブ・サイエンシズ 異常なレベル及び／又は活性のｉｆｐ３５ファミリーのタンパク質に関連する疾患又は障害を治療及び／又は予防するための方法及び組成物
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Also Published As

Publication number Publication date
EP2057286A4 (en) 2010-06-16
AU2007286915A2 (en) 2009-07-09
WO2008024642A8 (en) 2011-02-17
CA2695935A1 (en) 2008-02-28
AU2007286915A1 (en) 2008-02-28
JP2013066474A (ja) 2013-04-18
EP2057286A2 (en) 2009-05-13
WO2008024642A2 (en) 2008-02-28
CN101541976A (zh) 2009-09-23
SG177956A1 (en) 2012-02-28
WO2008024642A3 (en) 2008-12-04
AU2007286915B2 (en) 2014-05-15
US20080171323A1 (en) 2008-07-17

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