CN101541976A - 利用血液白细胞中的基因表达标记物的急性感染的鉴别诊断 - Google Patents

利用血液白细胞中的基因表达标记物的急性感染的鉴别诊断 Download PDF

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CN101541976A
CN101541976A CNA2007800381035A CN200780038103A CN101541976A CN 101541976 A CN101541976 A CN 101541976A CN A2007800381035 A CNA2007800381035 A CN A2007800381035A CN 200780038103 A CN200780038103 A CN 200780038103A CN 101541976 A CN101541976 A CN 101541976A
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genes
expression
patients
determining
gene
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Chinese (zh)
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J·F·班彻罗
A·K·帕吕卡
O·拉米罗
D·乔萨贝尔
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Baylor Research Institute
University of Texas System
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University of Texas System
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA2007800381035A 2006-08-11 2007-08-10 利用血液白细胞中的基因表达标记物的急性感染的鉴别诊断 Pending CN101541976A (zh)

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US83714806P 2006-08-11 2006-08-11
US60/837,148 2006-08-11

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CN101541976A true CN101541976A (zh) 2009-09-23

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US (1) US20080171323A1 (enExample)
EP (1) EP2057286A4 (enExample)
JP (2) JP2010500038A (enExample)
CN (1) CN101541976A (enExample)
AU (1) AU2007286915B2 (enExample)
CA (1) CA2695935A1 (enExample)
SG (1) SG177956A1 (enExample)
WO (1) WO2008024642A2 (enExample)

Cited By (17)

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CN103119444A (zh) * 2010-04-21 2013-05-22 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
CN104769430A (zh) * 2012-07-10 2015-07-08 尼平蓝山地方医疗区 流感中的风险分层
US9726668B2 (en) 2012-02-09 2017-08-08 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
CN108699583A (zh) * 2016-03-03 2018-10-23 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
CN108846258A (zh) * 2018-06-08 2018-11-20 中国人民解放军军事科学院军事医学研究院 一种自动检测分节段rna病毒重配的方法
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US10303846B2 (en) 2014-08-14 2019-05-28 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
CN111656191A (zh) * 2017-11-22 2020-09-11 D·雅克希斯 用于鉴别病毒性感染与细菌性感染的方法和设备
US10859574B2 (en) 2014-10-14 2020-12-08 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
CN112080559A (zh) * 2019-06-14 2020-12-15 复旦大学附属华山医院 Ppp1cb基因snp位点在制备检测寻常型银屑病易感性产品中的应用
US11131671B2 (en) 2016-07-10 2021-09-28 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
CN114236140A (zh) * 2021-12-27 2022-03-25 江苏贝索生物工程有限公司 基于试管法的血型智能判读方法
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
US12338497B2 (en) 2016-03-03 2025-06-24 Memed Diagnostics Ltd. Analyzing RNA for diagnosing infection type
US12392775B2 (en) 2014-12-11 2025-08-19 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof

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US9201068B2 (en) * 2008-09-03 2015-12-01 Clarkson University Bioelectronic tongue for food allergy detection
US10552710B2 (en) * 2009-09-28 2020-02-04 Oracle International Corporation Hierarchical sequential clustering
US10013641B2 (en) * 2009-09-28 2018-07-03 Oracle International Corporation Interactive dendrogram controls
US20110078194A1 (en) * 2009-09-28 2011-03-31 Oracle International Corporation Sequential information retrieval
KR101459186B1 (ko) 2012-04-26 2014-11-07 울산대학교 산학협력단 지속적 황색포도알균 균혈증의 조기 진단용 조성물 및 조기 진단방법
WO2015048098A1 (en) 2013-09-24 2015-04-02 Washington University Diagnostic methods for infectious disease using endogenous gene expression
WO2015103664A1 (en) * 2014-01-09 2015-07-16 Nepean Blue Montains Local Health District Risk stratification in influenza
CN107427552B (zh) * 2014-08-22 2022-12-20 广州英恩迈生物医药科技有限公司 防治与ifp35蛋白家族的异常水平和/或活性相关的疾病或不适的方法和组合物
CN105316404B (zh) * 2015-02-27 2017-02-22 中南大学湘雅二医院 系统性红斑狼疮生物标志物及其诊断试剂盒
JP7002037B2 (ja) * 2015-07-01 2022-02-04 デューク・ユニヴァーシティ 急性呼吸器感染症を診断および処置するための方法
WO2017004448A1 (en) * 2015-07-02 2017-01-05 Indevr, Inc. Methods of processing and classifying microarray data for the detection and characterization of pathogens
KR20170027258A (ko) * 2015-09-01 2017-03-09 제이더블유바이오사이언스 주식회사 트립토파닐 티알엔에이 합성효소를 이용한 패혈증의 진단용 조성물과 진단 마커 검출 방법
CN110656177A (zh) * 2019-10-15 2020-01-07 合肥艾迪康医学检验实验室有限公司 用于检测af1q基因相对表达量的引物、探针及方法和试剂盒
EP4058606A4 (en) * 2019-11-13 2024-02-28 The Regents Of The University Of Colorado, A Body Corporate Identification of host rna biomarkers of infection
JP2023536385A (ja) * 2020-05-29 2023-08-25 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア コロナウイルスを含む呼吸器ウイルスを検出する構成物および方法
JP2023145811A (ja) * 2020-08-17 2023-10-12 孝章 赤池 学習モデルの生成方法、プログラム、演算装置
US20220399116A1 (en) * 2021-05-04 2022-12-15 Inflammatix, Inc. Systems and methods for assessing a bacterial or viral status of a sample
US20240218468A1 (en) * 2021-05-11 2024-07-04 Inflammatix, Inc. Methods of diagnosis of respiratory viral infections
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US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US20040246906A1 (en) * 2003-06-06 2004-12-09 Hardy William Christopher Methods and systems for accelerating inference engines used in expert systems
US20050227222A1 (en) * 2004-04-09 2005-10-13 Massachusetts Institute Of Technology Pathogen identification method
US7608395B2 (en) * 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
US20100266610A1 (en) * 2007-05-03 2010-10-21 Medimmune, Llc Auto-antibody markers of autoimmune disease

Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103119444B (zh) * 2010-04-21 2016-10-26 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
CN106442984A (zh) * 2010-04-21 2017-02-22 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
US9709565B2 (en) 2010-04-21 2017-07-18 Memed Diagnostics Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
US9791446B2 (en) 2010-04-21 2017-10-17 Memed Diagnostics Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
CN103119444A (zh) * 2010-04-21 2013-05-22 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
CN106442984B (zh) * 2010-04-21 2020-03-13 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
US10502739B2 (en) 2012-02-09 2019-12-10 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US9726668B2 (en) 2012-02-09 2017-08-08 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US12188934B2 (en) 2012-02-09 2025-01-07 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US11175291B2 (en) 2012-02-09 2021-11-16 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
CN104769430A (zh) * 2012-07-10 2015-07-08 尼平蓝山地方医疗区 流感中的风险分层
CN104769430B (zh) * 2012-07-10 2018-12-14 尼平蓝山地方医疗区 流感中的风险分层
US11776658B2 (en) 2014-08-14 2023-10-03 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
US11450406B2 (en) 2014-08-14 2022-09-20 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
US11081206B2 (en) 2014-08-14 2021-08-03 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
US12131807B2 (en) 2014-08-14 2024-10-29 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
US10303846B2 (en) 2014-08-14 2019-05-28 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
US10859574B2 (en) 2014-10-14 2020-12-08 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
US12392775B2 (en) 2014-12-11 2025-08-19 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
US12338497B2 (en) 2016-03-03 2025-06-24 Memed Diagnostics Ltd. Analyzing RNA for diagnosing infection type
CN108699583A (zh) * 2016-03-03 2018-10-23 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
US11466331B2 (en) 2016-03-03 2022-10-11 Memed Diagnostics Ltd. RNA determinants for distinguishing between bacterial and viral infections
US12055545B2 (en) 2016-07-10 2024-08-06 Memed Diagnostics Ltd. Early diagnosis of infections
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
US12044681B2 (en) 2016-07-10 2024-07-23 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11131671B2 (en) 2016-07-10 2021-09-28 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US12228579B2 (en) 2016-09-29 2025-02-18 Memed Diagnostics Ltd. Methods of prognosis and treatment
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
CN111656191B (zh) * 2017-11-22 2023-11-14 德瓦克特实验室有限责任公司 用于鉴别病毒性感染与细菌性感染的方法和设备
CN111656191A (zh) * 2017-11-22 2020-09-11 D·雅克希斯 用于鉴别病毒性感染与细菌性感染的方法和设备
US12332242B2 (en) 2017-11-22 2025-06-17 Dewact Labs GmbH Method and device for discriminating between viral and bacterial infections
CN108846258A (zh) * 2018-06-08 2018-11-20 中国人民解放军军事科学院军事医学研究院 一种自动检测分节段rna病毒重配的方法
CN112080559B (zh) * 2019-06-14 2023-09-01 复旦大学附属华山医院 Ppp1cb基因snp位点在制备检测寻常型银屑病易感性产品中的应用
CN112080559A (zh) * 2019-06-14 2020-12-15 复旦大学附属华山医院 Ppp1cb基因snp位点在制备检测寻常型银屑病易感性产品中的应用
CN114236140A (zh) * 2021-12-27 2022-03-25 江苏贝索生物工程有限公司 基于试管法的血型智能判读方法
CN114236140B (zh) * 2021-12-27 2024-06-11 江苏贝索生物工程有限公司 基于试管法的血型智能判读方法

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CA2695935A1 (en) 2008-02-28
EP2057286A4 (en) 2010-06-16
AU2007286915A2 (en) 2009-07-09
JP2010500038A (ja) 2010-01-07
US20080171323A1 (en) 2008-07-17
SG177956A1 (en) 2012-02-28
AU2007286915A1 (en) 2008-02-28
EP2057286A2 (en) 2009-05-13
WO2008024642A8 (en) 2011-02-17
JP2013066474A (ja) 2013-04-18
AU2007286915B2 (en) 2014-05-15
WO2008024642A2 (en) 2008-02-28
WO2008024642A3 (en) 2008-12-04

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