|
US4826689A
(en)
|
1984-05-21 |
1989-05-02 |
University Of Rochester |
Method for making uniformly sized particles from water-insoluble organic compounds
|
|
US4783484A
(en)
|
1984-10-05 |
1988-11-08 |
University Of Rochester |
Particulate composition and use thereof as antimicrobial agent
|
|
IT1227626B
(it)
*
|
1988-11-28 |
1991-04-23 |
Vectorpharma Int |
Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
|
|
US5552160A
(en)
|
1991-01-25 |
1996-09-03 |
Nanosystems L.L.C. |
Surface modified NSAID nanoparticles
|
|
AU642066B2
(en)
|
1991-01-25 |
1993-10-07 |
Nanosystems L.L.C. |
X-ray contrast compositions useful in medical imaging
|
|
US5145684A
(en)
*
|
1991-01-25 |
1992-09-08 |
Sterling Drug Inc. |
Surface modified drug nanoparticles
|
|
US5399363A
(en)
*
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5338732A
(en)
*
|
1991-06-18 |
1994-08-16 |
Bristol-Myers Squibb Company |
Megestrol acetate formulation
|
|
JPH06511481A
(ja)
|
1991-07-05 |
1994-12-22 |
ユニバーシティ オブ ロチェスター |
気泡を取り込む超微小非凝集多孔質粒子
|
|
NZ248813A
(en)
|
1992-11-25 |
1995-06-27 |
Eastman Kodak Co |
Polymeric grinding media used in grinding pharmaceutical substances
|
|
US5349957A
(en)
|
1992-12-02 |
1994-09-27 |
Sterling Winthrop Inc. |
Preparation and magnetic properties of very small magnetite-dextran particles
|
|
US5298262A
(en)
|
1992-12-04 |
1994-03-29 |
Sterling Winthrop Inc. |
Use of ionic cloud point modifiers to prevent particle aggregation during sterilization
|
|
US5346702A
(en)
|
1992-12-04 |
1994-09-13 |
Sterling Winthrop Inc. |
Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
|
|
US5302401A
(en)
|
1992-12-09 |
1994-04-12 |
Sterling Winthrop Inc. |
Method to reduce particle size growth during lyophilization
|
|
US5340564A
(en)
|
1992-12-10 |
1994-08-23 |
Sterling Winthrop Inc. |
Formulations comprising olin 10-G to prevent particle aggregation and increase stability
|
|
US5336507A
(en)
|
1992-12-11 |
1994-08-09 |
Sterling Winthrop Inc. |
Use of charged phospholipids to reduce nanoparticle aggregation
|
|
US5429824A
(en)
|
1992-12-15 |
1995-07-04 |
Eastman Kodak Company |
Use of tyloxapole as a nanoparticle stabilizer and dispersant
|
|
US5352459A
(en)
|
1992-12-16 |
1994-10-04 |
Sterling Winthrop Inc. |
Use of purified surface modifiers to prevent particle aggregation during sterilization
|
|
US5326552A
(en)
|
1992-12-17 |
1994-07-05 |
Sterling Winthrop Inc. |
Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants
|
|
US5401492A
(en)
|
1992-12-17 |
1995-03-28 |
Sterling Winthrop, Inc. |
Water insoluble non-magnetic manganese particles as magnetic resonance contract enhancement agents
|
|
US5264610A
(en)
|
1993-03-29 |
1993-11-23 |
Sterling Winthrop Inc. |
Iodinated aromatic propanedioates
|
|
TW384224B
(en)
|
1994-05-25 |
2000-03-11 |
Nano Sys Llc |
Method of preparing submicron particles of a therapeutic or diagnostic agent
|
|
US5718388A
(en)
|
1994-05-25 |
1998-02-17 |
Eastman Kodak |
Continuous method of grinding pharmaceutical substances
|
|
US5525328A
(en)
|
1994-06-24 |
1996-06-11 |
Nanosystems L.L.C. |
Nanoparticulate diagnostic diatrizoxy ester X-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5587143A
(en)
|
1994-06-28 |
1996-12-24 |
Nanosystems L.L.C. |
Butylene oxide-ethylene oxide block copolymer surfactants as stabilizer coatings for nanoparticle compositions
|
|
US5628981A
(en)
|
1994-12-30 |
1997-05-13 |
Nano Systems L.L.C. |
Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents
|
|
US5585108A
(en)
|
1994-12-30 |
1996-12-17 |
Nanosystems L.L.C. |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
|
|
US5466440A
(en)
|
1994-12-30 |
1995-11-14 |
Eastman Kodak Company |
Formulations of oral gastrointestinal diagnostic X-ray contrast agents in combination with pharmaceutically acceptable clays
|
|
US5665331A
(en)
|
1995-01-10 |
1997-09-09 |
Nanosystems L.L.C. |
Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers
|
|
US5560932A
(en)
|
1995-01-10 |
1996-10-01 |
Nano Systems L.L.C. |
Microprecipitation of nanoparticulate pharmaceutical agents
|
|
US5662883A
(en)
|
1995-01-10 |
1997-09-02 |
Nanosystems L.L.C. |
Microprecipitation of micro-nanoparticulate pharmaceutical agents
|
|
US5569448A
(en)
|
1995-01-24 |
1996-10-29 |
Nano Systems L.L.C. |
Sulfated nonionic block copolymer surfactants as stabilizer coatings for nanoparticle compositions
|
|
US5560931A
(en)
|
1995-02-14 |
1996-10-01 |
Nawosystems L.L.C. |
Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
|
|
US5571536A
(en)
|
1995-02-06 |
1996-11-05 |
Nano Systems L.L.C. |
Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
|
|
US5593657A
(en)
|
1995-02-09 |
1997-01-14 |
Nanosystems L.L.C. |
Barium salt formulations stabilized by non-ionic and anionic stabilizers
|
|
US5534270A
(en)
|
1995-02-09 |
1996-07-09 |
Nanosystems Llc |
Method of preparing stable drug nanoparticles
|
|
US5622938A
(en)
|
1995-02-09 |
1997-04-22 |
Nano Systems L.L.C. |
Sugar base surfactant for nanocrystals
|
|
US5518738A
(en)
|
1995-02-09 |
1996-05-21 |
Nanosystem L.L.C. |
Nanoparticulate nsaid compositions
|
|
US5500204A
(en)
|
1995-02-10 |
1996-03-19 |
Eastman Kodak Company |
Nanoparticulate diagnostic dimers as x-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5591456A
(en)
|
1995-02-10 |
1997-01-07 |
Nanosystems L.L.C. |
Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer
|
|
US5573783A
(en)
|
1995-02-13 |
1996-11-12 |
Nano Systems L.L.C. |
Redispersible nanoparticulate film matrices with protective overcoats
|
|
US5510118A
(en)
|
1995-02-14 |
1996-04-23 |
Nanosystems Llc |
Process for preparing therapeutic compositions containing nanoparticles
|
|
US5543133A
(en)
|
1995-02-14 |
1996-08-06 |
Nanosystems L.L.C. |
Process of preparing x-ray contrast compositions containing nanoparticles
|
|
US5580579A
(en)
|
1995-02-15 |
1996-12-03 |
Nano Systems L.L.C. |
Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
|
|
US5565188A
(en)
|
1995-02-24 |
1996-10-15 |
Nanosystems L.L.C. |
Polyalkylene block copolymers as surface modifiers for nanoparticles
|
|
EP0810853B1
(en)
|
1995-02-24 |
2004-08-25 |
Elan Pharma International Limited |
Aerosols containing nanoparticle dispersions
|
|
US5718919A
(en)
|
1995-02-24 |
1998-02-17 |
Nanosystems L.L.C. |
Nanoparticles containing the R(-)enantiomer of ibuprofen
|
|
US5747001A
(en)
|
1995-02-24 |
1998-05-05 |
Nanosystems, L.L.C. |
Aerosols containing beclomethazone nanoparticle dispersions
|
|
US5472683A
(en)
|
1995-03-09 |
1995-12-05 |
Eastman Kodak Company |
Nanoparticulate diagnostic mixed carbamic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5643552A
(en)
|
1995-03-09 |
1997-07-01 |
Nanosystems L.L.C. |
Nanoparticulate diagnostic mixed carbonic anhydrides as x-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5573749A
(en)
|
1995-03-09 |
1996-11-12 |
Nano Systems L.L.C. |
Nanoparticulate diagnostic mixed carboxylic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5521218A
(en)
|
1995-05-15 |
1996-05-28 |
Nanosystems L.L.C. |
Nanoparticulate iodipamide derivatives for use as x-ray contrast agents
|
|
US5573750A
(en)
|
1995-05-22 |
1996-11-12 |
Nanosystems L.L.C. |
Diagnostic imaging x-ray contrast agents
|
|
US5834025A
(en)
|
1995-09-29 |
1998-11-10 |
Nanosystems L.L.C. |
Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions
|
|
US6045829A
(en)
|
1997-02-13 |
2000-04-04 |
Elan Pharma International Limited |
Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
|
|
WO1998035666A1
(en)
|
1997-02-13 |
1998-08-20 |
Nanosystems Llc |
Formulations of nanoparticle naproxen tablets
|
|
FR2775435B1
(fr)
*
|
1998-02-27 |
2000-05-26 |
Bioalliance Pharma |
Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs
|
|
US6268356B1
(en)
|
1998-04-20 |
2001-07-31 |
Pharmaceutical Resources, Inc. |
Flocculated suspension of megestrol acetate
|
|
US6028065A
(en)
*
|
1998-04-20 |
2000-02-22 |
Pharmaceutical Resources, Inc. |
Flocculated suspension of megestrol acetate
|
|
US6153225A
(en)
|
1998-08-13 |
2000-11-28 |
Elan Pharma International Limited |
Injectable formulations of nanoparticulate naproxen
|
|
US6165506A
(en)
|
1998-09-04 |
2000-12-26 |
Elan Pharma International Ltd. |
Solid dose form of nanoparticulate naproxen
|
|
US8293277B2
(en)
|
1998-10-01 |
2012-10-23 |
Alkermes Pharma Ireland Limited |
Controlled-release nanoparticulate compositions
|
|
US6428814B1
(en)
|
1999-10-08 |
2002-08-06 |
Elan Pharma International Ltd. |
Bioadhesive nanoparticulate compositions having cationic surface stabilizers
|
|
US6375986B1
(en)
|
2000-09-21 |
2002-04-23 |
Elan Pharma International Ltd. |
Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
|
|
US6270806B1
(en)
|
1999-03-03 |
2001-08-07 |
Elan Pharma International Limited |
Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions
|
|
US6267989B1
(en)
|
1999-03-08 |
2001-07-31 |
Klan Pharma International Ltd. |
Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions
|
|
JP4156807B2
(ja)
|
1999-06-01 |
2008-09-24 |
エラン ファーマ インターナショナル，リミティド |
小型ミル及びその方法
|
|
US6316029B1
(en)
|
2000-05-18 |
2001-11-13 |
Flak Pharma International, Ltd. |
Rapidly disintegrating solid oral dosage form
|
|
US20020028794A1
(en)
*
|
2000-07-21 |
2002-03-07 |
Brubaker Greg Allen |
Megestrol acetate suspension
|
|
NZ530826A
(en)
*
|
2001-06-29 |
2004-09-24 |
Eurand Pharmaceuticals Ltd |
Water-insoluble drugs co-ground with a cross-linked polymeric carrier in dry conditions so they are more soluble and bioavailable
|
|
US7101576B2
(en)
*
|
2002-04-12 |
2006-09-05 |
Elan Pharma International Limited |
Nanoparticulate megestrol formulations
|
|
UY28057A1
(es)
*
|
2002-10-31 |
2003-12-31 |
Alza Corp |
Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobos
|