JP2010183921A5 - - Google Patents
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- Publication number
- JP2010183921A5 JP2010183921A5 JP2010127963A JP2010127963A JP2010183921A5 JP 2010183921 A5 JP2010183921 A5 JP 2010183921A5 JP 2010127963 A JP2010127963 A JP 2010127963A JP 2010127963 A JP2010127963 A JP 2010127963A JP 2010183921 A5 JP2010183921 A5 JP 2010183921A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- acid sequence
- host cell
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 11
- 229920000023 polynucleotide Polymers 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 229920001850 Nucleic acid sequence Polymers 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 102000014909 interleukin-1 receptor activity proteins Human genes 0.000 claims 2
- 108040006732 interleukin-1 receptor activity proteins Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
Claims (7)
- 配列番号：２の核酸配列を含む、単離されたポリヌクレオチド。
- 配列番号：４のアミノ酸配列を含むポリペプチド、あるいは、配列番号：４のポリペプチドに少なくとも９５％同一のポリペプチドであって、ＩＬ−１Ｒファミリーメンバーに結合する前記ポリペプチド、をコードする核酸配列を含む、単離されたポリヌクレオチド。
- 配列番号：４のアミノ酸配列を含むポリペプチド、あるいは、配列番号：４のポリペプチドに少なくとも９５％同一のポリペプチドであって、ＩＬ−１Ｒファミリーメンバーに結合する前記ポリペプチド、含むポリペプチド。
- 請求項１又は２に記載のポリヌクレオチドを含む、発現ベクター。
- 請求項４に記載の発現ベクターで形質転換又はトランスフェクションした宿主細胞。
- 請求項５に記載の宿主細胞を、ポリペプチドの発現を促進する条件下で培養することを含む、ポリペプチドの製造方法。
- 請求項３に記載のポリペプチドを含むオリゴマーポリペプチド。
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11216398P | 1998-12-14 | 1998-12-14 | |
| US60/112,163 | 1998-12-14 | ||
| US16467599P | 1999-11-10 | 1999-11-10 | |
| US60/164,675 | 1999-11-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000588357A Division JP4562287B2 (ja) | 1998-12-14 | 1999-12-14 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010183921A JP2010183921A (ja) | 2010-08-26 |
| JP2010183921A5 true JP2010183921A5 (ja) | 2010-10-07 |
| JP5081277B2 JP5081277B2 (ja) | 2012-11-28 |
Family
ID=26809644
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000588357A Expired - Fee Related JP4562287B2 (ja) | 1998-12-14 | 1999-12-14 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
| JP2010127963A Expired - Fee Related JP5081277B2 (ja) | 1998-12-14 | 2010-06-03 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000588357A Expired - Fee Related JP4562287B2 (ja) | 1998-12-14 | 1999-12-14 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1141298B1 (ja) |
| JP (2) | JP4562287B2 (ja) |
| AT (2) | ATE428726T1 (ja) |
| AU (2) | AU775128B2 (ja) |
| CA (2) | CA2642146C (ja) |
| CY (1) | CY1105405T1 (ja) |
| DE (2) | DE69932259T2 (ja) |
| DK (1) | DK1141298T3 (ja) |
| ES (2) | ES2325165T3 (ja) |
| IL (2) | IL143361A0 (ja) |
| NZ (1) | NZ512749A (ja) |
| PT (1) | PT1141298E (ja) |
| WO (1) | WO2000036108A2 (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091181B2 (en) | 1994-12-12 | 2006-08-15 | Omeros Corporation | Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors |
| EP2319929A1 (en) | 1998-12-23 | 2011-05-11 | Genentech, Inc. | IL-1 related polypeptides |
| EP1092773A3 (en) * | 1999-10-15 | 2001-08-08 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Polypeptide and uses thereof |
| WO2016201503A1 (en) * | 2015-06-15 | 2016-12-22 | Monash University | Il-37 variants |
| CN106540242B (zh) * | 2016-11-24 | 2019-09-17 | 中国医学科学院医学实验动物研究所 | IL-1F7a的作用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1012160A4 (en) * | 1997-08-04 | 2002-10-29 | Millennium Pharm Inc | TANGO-72 AND TANGO-77 NUCLEIC ACID AND POLYPEPTID MOLECULES |
| WO1999006426A1 (en) * | 1997-08-04 | 1999-02-11 | Millennium Biotherapeutics, Inc. | Novel molecules of the tango-77 related protein family and uses thereof |
-
1999
- 1999-12-14 ES ES05025531T patent/ES2325165T3/es not_active Expired - Lifetime
- 1999-12-14 AT AT05025531T patent/ATE428726T1/de not_active IP Right Cessation
- 1999-12-14 DE DE69932259T patent/DE69932259T2/de not_active Expired - Lifetime
- 1999-12-14 DE DE69940750T patent/DE69940750D1/de not_active Expired - Lifetime
- 1999-12-14 CA CA2642146A patent/CA2642146C/en not_active Expired - Fee Related
- 1999-12-14 WO PCT/US1999/029549 patent/WO2000036108A2/en active IP Right Grant
- 1999-12-14 NZ NZ512749A patent/NZ512749A/en unknown
- 1999-12-14 JP JP2000588357A patent/JP4562287B2/ja not_active Expired - Fee Related
- 1999-12-14 DK DK99966182T patent/DK1141298T3/da active
- 1999-12-14 CA CA002353483A patent/CA2353483C/en not_active Expired - Fee Related
- 1999-12-14 PT PT99966182T patent/PT1141298E/pt unknown
- 1999-12-14 ES ES99966182T patent/ES2267311T3/es not_active Expired - Lifetime
- 1999-12-14 EP EP99966182A patent/EP1141298B1/en not_active Expired - Lifetime
- 1999-12-14 AU AU21788/00A patent/AU775128B2/en not_active Ceased
- 1999-12-14 IL IL14336199A patent/IL143361A0/xx active IP Right Grant
- 1999-12-14 AT AT99966182T patent/ATE332374T1/de not_active IP Right Cessation
-
2001
- 2001-05-24 IL IL143361A patent/IL143361A/en not_active IP Right Cessation
-
2004
- 2004-10-07 AU AU2004218668A patent/AU2004218668B2/en not_active Ceased
-
2006
- 2006-09-26 CY CY20061101377T patent/CY1105405T1/el unknown
-
2010
- 2010-06-03 JP JP2010127963A patent/JP5081277B2/ja not_active Expired - Fee Related
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