JP2010112955A5 - - Google Patents
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- Publication number
- JP2010112955A5 JP2010112955A5 JP2009267007A JP2009267007A JP2010112955A5 JP 2010112955 A5 JP2010112955 A5 JP 2010112955A5 JP 2009267007 A JP2009267007 A JP 2009267007A JP 2009267007 A JP2009267007 A JP 2009267007A JP 2010112955 A5 JP2010112955 A5 JP 2010112955A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- cell
- protein
- cells
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37170402P | 2002-04-12 | 2002-04-12 | |
| US60/371,704 | 2002-04-12 | ||
| US37941902P | 2002-05-13 | 2002-05-13 | |
| US60/379,419 | 2002-05-13 | ||
| US38757002P | 2002-06-12 | 2002-06-12 | |
| US60/387,570 | 2002-06-12 | ||
| US42289102P | 2002-11-01 | 2002-11-01 | |
| US60/422,891 | 2002-11-01 | ||
| US44255603P | 2003-01-27 | 2003-01-27 | |
| US60/442,556 | 2003-01-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584728A Division JP4542342B2 (ja) | 2002-04-12 | 2003-04-11 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012273726A Division JP5870016B2 (ja) | 2002-04-12 | 2012-12-14 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010112955A JP2010112955A (ja) | 2010-05-20 |
| JP2010112955A5 true JP2010112955A5 (cg-RX-API-DMAC7.html) | 2011-08-18 |
| JP5187910B2 JP5187910B2 (ja) | 2013-04-24 |
Family
ID=29255685
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584728A Expired - Lifetime JP4542342B2 (ja) | 2002-04-12 | 2003-04-11 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
| JP2009267007A Expired - Lifetime JP5187910B2 (ja) | 2002-04-12 | 2009-11-25 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
| JP2012273726A Expired - Lifetime JP5870016B2 (ja) | 2002-04-12 | 2012-12-14 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
| JP2015190891A Expired - Lifetime JP6168669B2 (ja) | 2002-04-12 | 2015-09-29 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584728A Expired - Lifetime JP4542342B2 (ja) | 2002-04-12 | 2003-04-11 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012273726A Expired - Lifetime JP5870016B2 (ja) | 2002-04-12 | 2012-12-14 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
| JP2015190891A Expired - Lifetime JP6168669B2 (ja) | 2002-04-12 | 2015-09-29 | 膜貫通型タンパク質と相互作用する化合物の同定法 |
Country Status (16)
| Country | Link |
|---|---|
| US (8) | US7309576B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2073013B1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP4542342B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN100399028C (cg-RX-API-DMAC7.html) |
| AT (1) | ATE421697T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2003218586B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2521946C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1108997T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60325953D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1495330T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2566487T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04011134A (cg-RX-API-DMAC7.html) |
| NZ (2) | NZ567458A (cg-RX-API-DMAC7.html) |
| PT (1) | PT1495330E (cg-RX-API-DMAC7.html) |
| SI (1) | SI1495330T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003087836A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2521946C (en) * | 2002-04-12 | 2013-10-15 | Brian F. O'dowd | Method of identifying transmembrane protein-interacting compounds |
| EP2138195A3 (en) * | 2004-06-16 | 2010-07-21 | Affinergy Inc. | IFBM's to promote attachment of target analytes |
| CN1944647B (zh) * | 2006-08-23 | 2010-05-12 | 华东师范大学 | 多巴胺受体新亚型d5b基因及编码的蛋白与应用 |
| JP4929462B2 (ja) | 2007-01-29 | 2012-05-09 | 国立大学法人高知大学 | 細胞膜上分子と相互作用する化合物の検出方法 |
| JP5213075B2 (ja) | 2007-06-15 | 2013-06-19 | ジェネラックス・コーポレイション | 腫瘍の画像化および／または処置のための微生物 |
| JP5230397B2 (ja) * | 2008-12-18 | 2013-07-10 | 独立行政法人科学技術振興機構 | 抗膜貫通型タンパク質抗体の抗原結合部位を決定する方法 |
| CN102580091B (zh) * | 2011-01-12 | 2014-12-10 | 中国科学院上海生命科学研究院 | 增强阿片镇痛剂的镇痛作用的方法及试剂 |
| US8643360B1 (en) * | 2012-09-02 | 2014-02-04 | George S. Cargill, III | In-water voltage gradient detector |
| TWI472617B (zh) * | 2012-09-17 | 2015-02-11 | Nat Univ Chung Hsing | 調控大分子進入細胞內之蛋白質及其調控大分子進入細胞內之方法 |
| US10513711B2 (en) | 2014-08-13 | 2019-12-24 | Dupont Us Holding, Llc | Genetic targeting in non-conventional yeast using an RNA-guided endonuclease |
| CA2966731C (en) | 2014-11-06 | 2023-01-31 | E. I. Du Pont De Nemours And Company | Peptide-mediated delivery of rna-guided endonuclease into cells |
| CA2985506A1 (en) | 2015-05-15 | 2016-11-24 | Pioneer Hi-Bred International, Inc. | Guide rna/cas endonuclease systems |
| WO2017066175A1 (en) | 2015-10-12 | 2017-04-20 | E. I. Du Pont De Nemours And Company | Protected dna templates for gene modification and increased homologous recombination in cells and methods of use |
| EP3365439A1 (en) | 2015-10-20 | 2018-08-29 | Pioneer Hi-Bred International, Inc. | Methods and compositions for marker-free genome modification |
| WO2017079026A1 (en) | 2015-11-06 | 2017-05-11 | E. I. Du Pont De Nemours And Company | Generation of complex trait loci in soybean and methods of use |
| WO2017100158A1 (en) | 2015-12-11 | 2017-06-15 | Danisco Us Inc. | Methods and compositions for enhanced nuclease-mediated genome modification and reduced off-target site effects |
| WO2017105991A1 (en) | 2015-12-18 | 2017-06-22 | Danisco Us Inc. | Methods and compositions for t-rna based guide rna expression |
| BR112018015348A2 (pt) | 2016-01-26 | 2018-12-18 | Pioneer Hi Bred Int | método para obter uma planta de milho ceroso, planta, semente, polinucleotídeo-guia e método para produzir uma planta híbrida de milho ceroso |
| WO2017155715A1 (en) | 2016-03-11 | 2017-09-14 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
| US20190161742A1 (en) | 2016-03-11 | 2019-05-30 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
| EP3426778A1 (en) | 2016-03-11 | 2019-01-16 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
| CA3022854A1 (en) | 2016-06-14 | 2017-12-21 | Pioneer Hi-Bred International, Inc. | Use of cpf1 endonuclease for plant genome modifications |
| CA3018430A1 (en) | 2016-06-20 | 2017-12-28 | Pioneer Hi-Bred International, Inc. | Novel cas systems and methods of use |
| EP4242330A3 (en) | 2016-10-13 | 2023-11-22 | Pioneer Hi-Bred International, Inc. | Generating northern leaf blight resistant maize |
| EP3551745A4 (en) * | 2016-12-12 | 2020-07-15 | Xcella Biosciences, Inc. | SCREENING METHODS AND SYSTEMS USING MICROCAPILLARY NETWORKS |
| US11156626B2 (en) | 2016-12-30 | 2021-10-26 | xCella Biosciences, Inc. | Multi-stage sample recovery system |
| US11519009B2 (en) | 2017-01-09 | 2022-12-06 | University Of Massachusetts | Complexes for gene deletion and editing |
| EP3707253A1 (en) | 2017-12-15 | 2020-09-16 | Danisco US Inc. | Cas9 variants and methods of use |
| CN108178790B (zh) * | 2018-01-18 | 2021-09-07 | 上海药明康德新药开发有限公司 | 一种将细胞膜分离以便对跨膜蛋白进行dna编码化合物库筛选的方法 |
| WO2019165168A1 (en) | 2018-02-23 | 2019-08-29 | Pioneer Hi-Bred International, Inc. | Novel cas9 orthologs |
| WO2020081173A1 (en) | 2018-10-16 | 2020-04-23 | Pioneer Hi-Bred International, Inc. | Genome edited fine mapping and causal gene identification |
| US12318775B2 (en) | 2018-12-06 | 2025-06-03 | xCella Biosciences, Inc. | Lateral loading of microcapillary arrays |
| CN113166744B (zh) | 2018-12-14 | 2025-02-07 | 先锋国际良种公司 | 用于基因组编辑的新颖crispr-cas系统 |
| AU2020205753B2 (en) | 2019-01-11 | 2025-05-29 | Omeros Corporation | Methods and compositions for treating cancer |
| EP3947656A1 (en) | 2019-04-05 | 2022-02-09 | Danisco US Inc. | Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof |
| CA3136114A1 (en) | 2019-04-05 | 2020-10-08 | Danisco Us Inc. | Methods for integrating a donor dna sequence into the genome of bacillus using linear recombinant dna constructs and compositions thereof |
| KR102329302B1 (ko) * | 2019-09-30 | 2021-11-22 | 한국과학기술연구원 | 도파민 d1형 수용체의 활성 측정용 적색 형광 단백질 기반 바이오센서 |
| WO2023105244A1 (en) | 2021-12-10 | 2023-06-15 | Pig Improvement Company Uk Limited | Editing tmprss2/4 for disease resistance in livestock |
| KR102833970B1 (ko) * | 2022-02-23 | 2025-07-17 | 충남대학교산학협력단 | 핵수송 신호 펩타이드가 접합된 핵산 전달용 2세대 폴리아미도아민 덴드리머 고분자 유도체 |
| WO2024013514A2 (en) | 2022-07-15 | 2024-01-18 | Pig Improvement Company Uk Limited | Gene edited livestock animals having coronavirus resistance |
| WO2024118881A1 (en) | 2022-12-01 | 2024-06-06 | Genencor International Bv | Iterative muliplex genome engineering in microbial cells using a bidirectional selection marker system |
| WO2024118882A1 (en) | 2022-12-01 | 2024-06-06 | Genencor International Bv | Iterative multiplex genome engineering in microbial cells using a selection marker swapping system |
| WO2024118876A1 (en) | 2022-12-01 | 2024-06-06 | Genencor International Bv | Iterative multiplex genome engineering in microbial cells using a recombinant self-excisable selection marker system |
| KR20250160500A (ko) | 2023-03-20 | 2025-11-13 | 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 | 변경된 pam 인식을 갖는 cas 폴리펩티드 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030022277A1 (en) * | 1995-05-05 | 2003-01-30 | Daniel R. Soppet | Human neuropeptide receptor |
| US6004808A (en) * | 1996-06-21 | 1999-12-21 | Aurora Biosciences Corporation | Promiscuous G-protein compositions and their use |
| US5891646A (en) | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
| US6383761B2 (en) * | 1997-07-28 | 2002-05-07 | The Regents Of The University Of California | Methods and compositions for identifying modulators of G-protein-coupled receptors |
| AU2001241463A1 (en) * | 2000-02-09 | 2001-08-20 | Human Genome Sciences, Inc. | Human g-protein chemokine receptor (CCR5) HDGNR10 |
| WO2002014475A2 (en) | 2000-08-16 | 2002-02-21 | The Trustees Of Columbia University In The City Of New York | QUANTITATIVE ASSESSMENT OF erbB/HER RECEPTORS IN BIOLOGICAL FLUIDS |
| CA2521946C (en) | 2002-04-12 | 2013-10-15 | Brian F. O'dowd | Method of identifying transmembrane protein-interacting compounds |
-
2003
- 2003-04-11 CA CA2521946A patent/CA2521946C/en not_active Expired - Lifetime
- 2003-04-11 PT PT03711772T patent/PT1495330E/pt unknown
- 2003-04-11 JP JP2003584728A patent/JP4542342B2/ja not_active Expired - Lifetime
- 2003-04-11 EP EP09150972.9A patent/EP2073013B1/en not_active Expired - Lifetime
- 2003-04-11 ES ES09150972.9T patent/ES2566487T3/es not_active Expired - Lifetime
- 2003-04-11 SI SI200331562T patent/SI1495330T1/sl unknown
- 2003-04-11 AU AU2003218586A patent/AU2003218586B2/en not_active Expired
- 2003-04-11 EP EP03711772A patent/EP1495330B1/en not_active Expired - Lifetime
- 2003-04-11 AT AT03711772T patent/ATE421697T1/de active
- 2003-04-11 CN CNB038082977A patent/CN100399028C/zh not_active Expired - Lifetime
- 2003-04-11 WO PCT/CA2003/000542 patent/WO2003087836A1/en not_active Ceased
- 2003-04-11 US US10/509,787 patent/US7309576B2/en not_active Expired - Lifetime
- 2003-04-11 DK DK03711772T patent/DK1495330T3/da active
- 2003-04-11 ES ES03711772T patent/ES2321704T3/es not_active Expired - Lifetime
- 2003-04-11 NZ NZ567458A patent/NZ567458A/en not_active IP Right Cessation
- 2003-04-11 DE DE60325953T patent/DE60325953D1/de not_active Expired - Lifetime
- 2003-04-11 MX MXPA04011134A patent/MXPA04011134A/es active IP Right Grant
- 2003-04-11 NZ NZ536063A patent/NZ536063A/en not_active IP Right Cessation
- 2003-04-11 EP EP10181657A patent/EP2339347A1/en not_active Withdrawn
-
2007
- 2007-11-08 US US11/937,275 patent/US7794955B2/en not_active Expired - Lifetime
-
2009
- 2009-03-26 AU AU2009201195A patent/AU2009201195B2/en not_active Expired
- 2009-04-16 CY CY20091100453T patent/CY1108997T1/el unknown
- 2009-11-25 JP JP2009267007A patent/JP5187910B2/ja not_active Expired - Lifetime
-
2010
- 2010-07-12 US US12/834,351 patent/US8298777B2/en not_active Expired - Fee Related
-
2012
- 2012-09-25 US US13/626,294 patent/US9005905B2/en not_active Expired - Fee Related
- 2012-12-14 JP JP2012273726A patent/JP5870016B2/ja not_active Expired - Lifetime
-
2015
- 2015-03-13 US US14/657,754 patent/US20150377896A1/en not_active Abandoned
- 2015-09-29 JP JP2015190891A patent/JP6168669B2/ja not_active Expired - Lifetime
-
2017
- 2017-03-07 US US15/452,502 patent/US20170336418A1/en not_active Abandoned
-
2018
- 2018-03-14 US US15/921,371 patent/US20180267051A1/en not_active Abandoned
- 2018-12-18 US US16/224,656 patent/US20190317105A1/en not_active Abandoned
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