JP2009541205A - P2x7調節因子としてのビシクロへテロアリール化合物およびその使用 - Google Patents

P2x7調節因子としてのビシクロへテロアリール化合物およびその使用 Download PDF

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JP2009541205A
JP2009541205A JP2009500513A JP2009500513A JP2009541205A JP 2009541205 A JP2009541205 A JP 2009541205A JP 2009500513 A JP2009500513 A JP 2009500513A JP 2009500513 A JP2009500513 A JP 2009500513A JP 2009541205 A JP2009541205 A JP 2009541205A
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disease
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JP2009541205A5 (enExample
Inventor
マイケル ジー. ケリー,
ジョン キンケード,
ユンフェン ファン,
イェユー カオ,
カール カウブ,
スミスラ ゴウルガリ,
チャン ワン,
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レノビス, インコーポレイテッド
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Priority claimed from PCT/US2007/006676 external-priority patent/WO2007109154A2/en
Publication of JP2009541205A publication Critical patent/JP2009541205A/ja
Publication of JP2009541205A5 publication Critical patent/JP2009541205A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
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    • C—CHEMISTRY; METALLURGY
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    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
JP2009500513A 2006-03-16 2007-03-16 P2x7調節因子としてのビシクロへテロアリール化合物およびその使用 Withdrawn JP2009541205A (ja)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US78330406P 2006-03-16 2006-03-16
US78292306P 2006-03-16 2006-03-16
US78292206P 2006-03-16 2006-03-16
US78359006P 2006-03-16 2006-03-16
US78312106P 2006-03-16 2006-03-16
US78374806P 2006-03-16 2006-03-16
US78297306P 2006-03-16 2006-03-16
US78277506P 2006-03-16 2006-03-16
US78277606P 2006-03-16 2006-03-16
US78278206P 2006-03-16 2006-03-16
US83141606P 2006-07-17 2006-07-17
US84699306P 2006-09-25 2006-09-25
US91812307P 2007-03-15 2007-03-15
PCT/US2007/006676 WO2007109154A2 (en) 2006-03-16 2007-03-16 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

Publications (2)

Publication Number Publication Date
JP2009541205A true JP2009541205A (ja) 2009-11-26
JP2009541205A5 JP2009541205A5 (enExample) 2011-03-31

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ID=39878008

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JP2009500513A Withdrawn JP2009541205A (ja) 2006-03-16 2007-03-16 P2x7調節因子としてのビシクロへテロアリール化合物およびその使用

Country Status (3)

Country Link
US (1) US20090298825A1 (enExample)
EP (1) EP1996585A4 (enExample)
JP (1) JP2009541205A (enExample)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0200920D0 (sv) * 2002-03-25 2002-03-25 Astrazeneca Ab Novel compounds
AU2003301443A1 (en) * 2002-10-18 2004-05-04 E.I. Du Pont De Nemours And Company Azolecarboxamide herbicides
GB0312609D0 (en) * 2003-06-02 2003-07-09 Astrazeneca Ab Novel compounds

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Publication number Publication date
EP1996585A2 (en) 2008-12-03
US20090298825A1 (en) 2009-12-03
EP1996585A4 (en) 2010-03-10

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