JP2009536967A5 - - Google Patents
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- Publication number
- JP2009536967A5 JP2009536967A5 JP2009511159A JP2009511159A JP2009536967A5 JP 2009536967 A5 JP2009536967 A5 JP 2009536967A5 JP 2009511159 A JP2009511159 A JP 2009511159A JP 2009511159 A JP2009511159 A JP 2009511159A JP 2009536967 A5 JP2009536967 A5 JP 2009536967A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- carbon atoms
- alkyl
- substituted
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims description 10
- 229910052760 oxygen Inorganic materials 0.000 claims description 7
- 229910052717 sulfur Inorganic materials 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 239000000651 prodrug Substances 0.000 claims description 4
- 229940002612 prodrug Drugs 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 125000001072 heteroaryl group Chemical group 0.000 claims description 3
- 125000003107 substituted aryl group Chemical group 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims 15
- 208000010412 Glaucoma Diseases 0.000 claims 3
- 206010030043 Ocular hypertension Diseases 0.000 claims 3
- -1 6-hexyl Chemical group 0.000 claims 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical group CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 150000001408 amides Chemical class 0.000 claims 1
- 235000010290 biphenyl Nutrition 0.000 claims 1
- 239000004305 biphenyl Substances 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 claims 1
- 125000005549 heteroarylene group Chemical group 0.000 claims 1
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
- 150000007524 organic acids Chemical group 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 125000003831 tetrazolyl group Chemical group 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74711506P | 2006-05-12 | 2006-05-12 | |
| US11/745,317 US7557095B2 (en) | 2006-05-12 | 2007-05-07 | Therapeutic compounds |
| PCT/US2007/068518 WO2007134085A2 (en) | 2006-05-12 | 2007-05-09 | Isothiazolidines useful in the treatment of ocular hypertensive conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009536967A JP2009536967A (ja) | 2009-10-22 |
| JP2009536967A5 true JP2009536967A5 (OSRAM) | 2010-06-24 |
Family
ID=38606676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511159A Pending JP2009536967A (ja) | 2006-05-12 | 2007-05-09 | 高眼圧症状治療に有用なイソチアゾリジン類 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7557095B2 (OSRAM) |
| EP (1) | EP2044041A2 (OSRAM) |
| JP (1) | JP2009536967A (OSRAM) |
| AU (1) | AU2007249443B2 (OSRAM) |
| BR (1) | BRPI0711461A2 (OSRAM) |
| CA (1) | CA2652866A1 (OSRAM) |
| WO (1) | WO2007134085A2 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7557095B2 (en) * | 2006-05-12 | 2009-07-07 | Allergan, Inc. | Therapeutic compounds |
| US7960379B2 (en) * | 2008-03-14 | 2011-06-14 | Allergan, Inc. | Therapeutic compounds |
| US8314250B2 (en) * | 2009-11-24 | 2012-11-20 | Hoffmann-La Roche Inc. | Sultam derivatives |
| US8999889B2 (en) | 2010-02-01 | 2015-04-07 | Basf Se | Substituted ketonic isoxazoline compounds and derivatives for combating animal pests |
| AR083646A1 (es) | 2010-10-01 | 2013-03-13 | Basf Se | Compuestos de imina, composiciones veterinarias y agricolas que los contienen y su uso en el control de plagas de invertebrados |
| WO2012042006A1 (en) | 2010-10-01 | 2012-04-05 | Basf Se | Imine compounds |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5462968A (en) * | 1994-01-19 | 1995-10-31 | Allergan, Inc. | EP2 -receptor agonists as agents for lowering intraocular pressure |
| US5519040A (en) | 1994-04-29 | 1996-05-21 | Allergan | Substituted thiazole sulfonamides as antiglaucoma agents |
| US5902726A (en) | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
| TW401408B (en) | 1995-07-21 | 2000-08-11 | Fujisawa Pharmaceutical Co | Heterocyclic compounds having prostaglandin I2 agonism |
| US5877211A (en) * | 1997-11-21 | 1999-03-02 | Allergan | EP2 receptor agonists as neuroprotective agents for the eye |
| US6465501B2 (en) | 2000-07-17 | 2002-10-15 | Wyeth | Azolidines as β3 adrenergic receptor agonists |
| US6927216B2 (en) * | 2000-10-03 | 2005-08-09 | Bristol-Myers Squibb Pharma Company | Cyclic sulfonyl compounds as inhibitors of metalloproteases |
| US6476064B1 (en) | 2001-06-13 | 2002-11-05 | Allergan, Inc. | Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents |
| CA2463102C (en) * | 2001-10-23 | 2011-05-10 | Applied Research Systems Ars Holding N.V. | Pyrazolidinone compounds as ligands of the prostaglandin ep2 and/or ep4 receptors |
| DE60235198D1 (de) * | 2001-12-20 | 2010-03-11 | Merck Serono Sa Coinsins | Pyrrolidin-derivatie als prostaglandin-modulatoren |
| WO2003074483A1 (en) * | 2002-03-05 | 2003-09-12 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
| JP2005104836A (ja) * | 2003-08-08 | 2005-04-21 | Ono Pharmaceut Co Ltd | プロスタグランジン誘導体 |
| US7557095B2 (en) * | 2006-05-12 | 2009-07-07 | Allergan, Inc. | Therapeutic compounds |
| US7960379B2 (en) * | 2008-03-14 | 2011-06-14 | Allergan, Inc. | Therapeutic compounds |
-
2007
- 2007-05-07 US US11/745,317 patent/US7557095B2/en active Active
- 2007-05-09 JP JP2009511159A patent/JP2009536967A/ja active Pending
- 2007-05-09 WO PCT/US2007/068518 patent/WO2007134085A2/en not_active Ceased
- 2007-05-09 CA CA002652866A patent/CA2652866A1/en not_active Abandoned
- 2007-05-09 BR BRPI0711461-3A patent/BRPI0711461A2/pt not_active IP Right Cessation
- 2007-05-09 AU AU2007249443A patent/AU2007249443B2/en not_active Ceased
- 2007-05-09 EP EP07762032A patent/EP2044041A2/en not_active Withdrawn
-
2009
- 2009-06-02 US US12/476,467 patent/US7897629B2/en active Active
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