JP2009535644A - バイオマーカーを使用して疾患状況を同定するための方法および装置 - Google Patents

バイオマーカーを使用して疾患状況を同定するための方法および装置 Download PDF

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JP2009535644A
JP2009535644A JP2009509959A JP2009509959A JP2009535644A JP 2009535644 A JP2009535644 A JP 2009535644A JP 2009509959 A JP2009509959 A JP 2009509959A JP 2009509959 A JP2009509959 A JP 2009509959A JP 2009535644 A JP2009535644 A JP 2009535644A
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グライムス エフ. ランドール,
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プロビスタ ダイアグノスティクス, エルエルシー
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JP2009509959A 2006-05-01 2007-04-25 バイオマーカーを使用して疾患状況を同定するための方法および装置 Withdrawn JP2009535644A (ja)

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US11/381,104 US20070255113A1 (en) 2006-05-01 2006-05-01 Methods and apparatus for identifying disease status using biomarkers
PCT/US2007/067418 WO2007130831A2 (en) 2006-05-01 2007-04-25 Methods and apparatus for identifying disease status using biomarkers

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US (5) US20070255113A1 (https=)
EP (2) EP2016405B1 (https=)
JP (1) JP2009535644A (https=)
KR (1) KR20090024686A (https=)
CN (1) CN101479599A (https=)
AU (1) AU2007248299A1 (https=)
BR (1) BRPI0711148A2 (https=)
CA (1) CA2650872C (https=)
IL (1) IL195054A0 (https=)
MX (1) MX2008013978A (https=)
RU (1) RU2008147223A (https=)
WO (1) WO2007130831A2 (https=)
ZA (1) ZA200809968B (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
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JP2014121323A (ja) * 2012-12-21 2014-07-03 Stembios Technologies Inc 幹細胞による行為効果を評価する方法
JP2017516085A (ja) * 2014-04-08 2017-06-15 メタボルン インコーポレーティッド 疾患診断および健康評価のための個々の対象の低分子生化学プロファイリングの方法
US10143710B2 (en) 2010-08-04 2018-12-04 StemBios Technologies, Inc. Somatic stem cells
US11492592B2 (en) 2012-12-06 2022-11-08 StemBios Technologies, Inc. Lgr5+ somatic stem cells
JP2023086821A (ja) * 2016-01-22 2023-06-22 オートレイシーズ,インク. 疾患診断を改善するシステム及び方法
JP2023156388A (ja) * 2013-03-14 2023-10-24 オートレイシーズ・インコーポレイテッド 測定分析物を使用する、疾患診断を改善するための方法

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158374B1 (en) 2006-09-05 2012-04-17 Ridge Diagnostics, Inc. Quantitative diagnostic methods using multiple parameters
US20090047694A1 (en) * 2007-08-17 2009-02-19 Shuber Anthony P Clinical Intervention Directed Diagnostic Methods
US8431367B2 (en) 2007-09-14 2013-04-30 Predictive Biosciences Corporation Detection of nucleic acids and proteins
US20090075266A1 (en) * 2007-09-14 2009-03-19 Predictive Biosciences Corporation Multiple analyte diagnostic readout
US20100267041A1 (en) * 2007-09-14 2010-10-21 Predictive Biosciences, Inc. Serial analysis of biomarkers for disease diagnosis
US7955822B2 (en) * 2007-09-14 2011-06-07 Predictive Biosciences Corp. Detection of nucleic acids and proteins
US8440418B2 (en) 2008-11-18 2013-05-14 Ridge Diagnostics, Inc. Metabolic syndrome and HPA axis biomarkers for major depressive disorder
US20110245092A1 (en) * 2008-03-04 2011-10-06 John Bilello Diagnosing and monitoring depression disorders based on multiple serum biomarker panels
WO2009114627A2 (en) * 2008-03-12 2009-09-17 Ridge Diagnostics, Inc. Inflammatory biomarkers for monitoring depression disorders
ES2665245T3 (es) 2008-08-11 2018-04-25 Banyan Biomarkers, Inc. Proceso de detección de biomarcador y ensayo de estado neurológico
US12601749B2 (en) 2008-08-11 2026-04-14 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
US20140342381A1 (en) * 2008-08-11 2014-11-20 Banyan Biomarkers, Inc. Devices and methods for biomarker detection process and assay of neurological condition
EP2471016A1 (en) * 2009-08-28 2012-07-04 Lexicor Medical Technology, LLC Systems and methods to identify a subgroup of adhd at higher risk for complicating conditions
US20150127378A1 (en) * 2012-02-11 2015-05-07 Yougene Corp. Systems for storing, processing and utilizing proprietary genetic information
JP6075973B2 (ja) * 2012-06-04 2017-02-08 富士通株式会社 健康状態判定装置およびその作動方法
EP2684513A1 (en) 2012-07-13 2014-01-15 Universite D'angers Method for providing reliable non-invasive diagnostic tests
US20140275294A1 (en) * 2013-03-15 2014-09-18 Banyan Biomarkers, Inc. Devices and methods for biomarker detection process and assay of liver injury
CN103279655A (zh) * 2013-05-20 2013-09-04 浙江大学 一种恶性肿瘤放化疗规范符合度的评估方法
CN105431853B (zh) 2013-05-23 2018-12-28 艾弗诺泰普有限责任公司 表型整合的社会研究数据库和方法
US10190169B2 (en) 2013-06-20 2019-01-29 Immunexpress Pty Ltd Biomarker identification
PL3084664T3 (pl) * 2013-12-16 2020-10-05 Philip Morris Products S.A. Układy i sposoby do przewidywania statusu palenia u osobnika
US11047010B2 (en) 2014-02-06 2021-06-29 Immunexpress Pty Ltd Biomarker signature method, and apparatus and kits thereof
US9176113B1 (en) 2014-04-11 2015-11-03 Synapdx Corporation Methods and systems for determining autism spectrum disorder risk
US20150294081A1 (en) 2014-04-11 2015-10-15 Synapdx Corporation Methods and systems for determining autism spectrum disorder risk
US10525020B2 (en) 2015-02-11 2020-01-07 Laboratory Corporation Of America Holdings Metabolic markers of attention deficit hyperactivity disorder
AU2016267392B2 (en) * 2015-05-28 2021-12-09 Immunexpress Pty Ltd Validating biomarker measurement
US11594311B1 (en) 2016-03-31 2023-02-28 OM1, Inc. Health care information system providing standardized outcome scores across patients
US11957897B2 (en) 2016-04-22 2024-04-16 Newton Howard Biological co-processor (BCP)
WO2018081649A1 (en) 2016-10-28 2018-05-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin c-terminal hydrolase l1 (uch-l1) and glial fibrillary acidic protein (gfap) and related methods
WO2019183052A1 (en) * 2018-03-19 2019-09-26 Sri International Methods and systems for biomarker analysis
US20190302119A1 (en) * 2018-03-27 2019-10-03 Lawrence Abraham Cancer Diagnostic Metastasis Panel
US11967428B1 (en) * 2018-04-17 2024-04-23 OM1, Inc. Applying predictive models to data representing a history of events
CA3003032A1 (en) * 2018-04-27 2019-10-27 Nanostics Inc. Methods of diagnosing disease using microflow cytometry
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US11862346B1 (en) 2018-12-22 2024-01-02 OM1, Inc. Identification of patient sub-cohorts and corresponding quantitative definitions of subtypes as a classification system for medical conditions
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US20200395097A1 (en) * 2019-05-30 2020-12-17 Tempus Labs, Inc. Pan-cancer model to predict the pd-l1 status of a cancer cell sample using rna expression data and other patient data
TWI740647B (zh) * 2020-09-15 2021-09-21 宏碁股份有限公司 疾病分類方法及疾病分類裝置
US20220223231A1 (en) * 2021-01-14 2022-07-14 The Board Of Trustees Of The Leland Stanford Junior University Systems and Methods for Improved Prognostics in Medical Imaging
KR102671925B1 (ko) * 2022-03-03 2024-06-03 인제대학교 산학협력단 파킨슨병 진단 방법 및 그 시스템

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197532B1 (en) * 1998-01-22 2001-03-06 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Diagnosis and detection of breast cancer and other cancers
CA2300639A1 (en) * 1999-03-15 2000-09-15 Whitehead Institute For Biomedical Research Methods and apparatus for analyzing gene expression data
US6647341B1 (en) * 1999-04-09 2003-11-11 Whitehead Institute For Biomedical Research Methods for classifying samples and ascertaining previously unknown classes
US6714925B1 (en) * 1999-05-01 2004-03-30 Barnhill Technologies, Llc System for identifying patterns in biological data using a distributed network
US6750013B2 (en) * 1999-12-02 2004-06-15 Protein Design Labs, Inc. Methods for detection and diagnosing of breast cancer
US20030087865A1 (en) * 2001-07-13 2003-05-08 Whitehead Institute For Biomedical Research Leukemogenic transcription factors
US20030225526A1 (en) * 2001-11-14 2003-12-04 Golub Todd R. Molecular cancer diagnosis using tumor gene expression signature
US6949342B2 (en) * 2001-12-21 2005-09-27 Whitehead Institute For Biomedical Research Prostate cancer diagnosis and outcome prediction by expression analysis
US20040076974A1 (en) * 2002-04-01 2004-04-22 Kier Larry D. Liver necrosis predictive genes
US20050176057A1 (en) * 2003-09-26 2005-08-11 Troy Bremer Diagnostic markers of mood disorders and methods of use thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10143710B2 (en) 2010-08-04 2018-12-04 StemBios Technologies, Inc. Somatic stem cells
US11492592B2 (en) 2012-12-06 2022-11-08 StemBios Technologies, Inc. Lgr5+ somatic stem cells
JP2014121323A (ja) * 2012-12-21 2014-07-03 Stembios Technologies Inc 幹細胞による行為効果を評価する方法
JP2023156388A (ja) * 2013-03-14 2023-10-24 オートレイシーズ・インコーポレイテッド 測定分析物を使用する、疾患診断を改善するための方法
JP7603115B2 (ja) 2013-03-14 2024-12-19 オートレイシーズ・インコーポレイテッド 測定分析物を使用する、疾患診断を改善するための方法
JP2017516085A (ja) * 2014-04-08 2017-06-15 メタボルン インコーポレーティッド 疾患診断および健康評価のための個々の対象の低分子生化学プロファイリングの方法
JP2023086821A (ja) * 2016-01-22 2023-06-22 オートレイシーズ,インク. 疾患診断を改善するシステム及び方法

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EP2016405A2 (en) 2009-01-21
US20110077931A1 (en) 2011-03-31
CA2650872C (en) 2018-04-24
BRPI0711148A2 (pt) 2011-08-23
EP2016405A4 (en) 2012-10-03
US20070254369A1 (en) 2007-11-01
MX2008013978A (es) 2009-02-19
EP2016405B1 (en) 2017-09-27
KR20090024686A (ko) 2009-03-09
CN101479599A (zh) 2009-07-08
AU2007248299A1 (en) 2007-11-15
EP3318995A1 (en) 2018-05-09
US20070255113A1 (en) 2007-11-01
CA2650872A1 (en) 2007-11-15
ZA200809968B (en) 2009-08-26
US20210041440A1 (en) 2021-02-11
IL195054A0 (en) 2009-08-03
WO2007130831A2 (en) 2007-11-15
US20130060549A1 (en) 2013-03-07
WO2007130831A3 (en) 2008-10-30
RU2008147223A (ru) 2010-06-10

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