JP2009533472A5 - - Google Patents
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- Publication number
- JP2009533472A5 JP2009533472A5 JP2009505614A JP2009505614A JP2009533472A5 JP 2009533472 A5 JP2009533472 A5 JP 2009533472A5 JP 2009505614 A JP2009505614 A JP 2009505614A JP 2009505614 A JP2009505614 A JP 2009505614A JP 2009533472 A5 JP2009533472 A5 JP 2009533472A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- halo
- alkoxy
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCC=*C=C1C(N[U])=NC(O)=NC1=* Chemical compound CCC=*C=C1C(N[U])=NC(O)=NC1=* 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79184106P | 2006-04-13 | 2006-04-13 | |
| PCT/US2007/066478 WO2007121279A2 (en) | 2006-04-13 | 2007-04-12 | Cancer treatment method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009533472A JP2009533472A (ja) | 2009-09-17 |
| JP2009533472A5 true JP2009533472A5 (https=) | 2010-05-20 |
Family
ID=38610376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009505614A Pending JP2009533472A (ja) | 2006-04-13 | 2007-04-12 | 癌治療法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090203718A1 (https=) |
| EP (1) | EP2012587A2 (https=) |
| JP (1) | JP2009533472A (https=) |
| WO (1) | WO2007121279A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010236818B2 (en) * | 2009-04-16 | 2014-03-13 | Merck Sharp & Dohme Corp. | Combination therapy using an anti-EGFR agent(s) and IGF-1R specific inhibitors |
| US8623604B2 (en) * | 2009-09-09 | 2014-01-07 | Quintiles Transnational Corp. | Methods for predicting responsiveness of a cancer cell to an anti-IGFR1 antibody by analysis of mutations in PIK3CA |
| ES2576871T3 (es) * | 2010-03-23 | 2016-07-11 | Scinopharm Taiwan Ltd. | Proceso e intermedios para preparar lapatinib |
| WO2012026511A1 (ja) * | 2010-08-27 | 2012-03-01 | 協和発酵キリン株式会社 | 医薬組成物 |
| ITMI20110894A1 (it) | 2011-05-20 | 2012-11-21 | Italiana Sint Spa | Impurezza del lapatinib e suoi sali |
| WO2014170910A1 (en) | 2013-04-04 | 2014-10-23 | Natco Pharma Limited | Process for the preparation of lapatinib |
| US20220143049A1 (en) | 2019-03-21 | 2022-05-12 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS49779B (sr) * | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze |
| PL204958B1 (pl) * | 2000-06-30 | 2010-02-26 | Glaxo Group Ltd | Ditosylany związków chinazolinowych, środek farmaceutyczny i zastosowanie tych związków |
| AR035885A1 (es) * | 2001-05-14 | 2004-07-21 | Novartis Ag | Derivados de 4-amino-5-fenil-7-ciclobutilpirrolo (2,3-d)pirimidina, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos derivados para la preparacion de una composicion farmaceutica |
| ATE514434T1 (de) * | 2004-02-25 | 2011-07-15 | Dana Farber Cancer Inst Inc | Hemmer des insulinartigen wachstumsfaktor- rezeptors-1 zur hemmung von tumorzellwachstum |
| US20050272637A1 (en) * | 2004-04-22 | 2005-12-08 | Oregon Health & Science University | Compositions and methods for modulating signaling mediated by IGF-1 receptor and erbB receptors |
-
2006
- 2006-04-13 US US12/296,972 patent/US20090203718A1/en not_active Abandoned
-
2007
- 2007-04-12 JP JP2009505614A patent/JP2009533472A/ja active Pending
- 2007-04-12 EP EP07781778A patent/EP2012587A2/en not_active Withdrawn
- 2007-04-12 WO PCT/US2007/066478 patent/WO2007121279A2/en not_active Ceased