JP2009532326A - ジンクフィンガータンパク質により末梢動脈疾患を処置するための方法 - Google Patents

ジンクフィンガータンパク質により末梢動脈疾患を処置するための方法 Download PDF

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JP2009532326A
JP2009532326A JP2008554385A JP2008554385A JP2009532326A JP 2009532326 A JP2009532326 A JP 2009532326A JP 2008554385 A JP2008554385 A JP 2008554385A JP 2008554385 A JP2008554385 A JP 2008554385A JP 2009532326 A JP2009532326 A JP 2009532326A
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Prior art keywords
zinc finger
finger protein
nucleic acid
patient
vegf
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JP2008554385A
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Japanese (ja)
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JP2009532326A5 (https=
Inventor
パトリス トレンブル
ジョー ロコビッチ
ブライアン アネックス
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Sangamo Therapeutics Inc
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Sangamo Therapeutics Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2008554385A 2006-02-09 2007-02-09 ジンクフィンガータンパク質により末梢動脈疾患を処置するための方法 Pending JP2009532326A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77241706P 2006-02-09 2006-02-09
US80323406P 2006-05-25 2006-05-25
PCT/US2007/003538 WO2007092609A2 (en) 2006-02-09 2007-02-09 Method for treating peripheral arterial disease with zinc finger proteins

Publications (2)

Publication Number Publication Date
JP2009532326A true JP2009532326A (ja) 2009-09-10
JP2009532326A5 JP2009532326A5 (https=) 2010-03-25

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JP2008554385A Pending JP2009532326A (ja) 2006-02-09 2007-02-09 ジンクフィンガータンパク質により末梢動脈疾患を処置するための方法

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US (1) US20090305977A1 (https=)
EP (1) EP1993586A4 (https=)
JP (1) JP2009532326A (https=)
AU (1) AU2007212260A1 (https=)
CA (1) CA2641198A1 (https=)
WO (1) WO2007092609A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024515250A (ja) * 2021-04-07 2024-04-08 リジェン イノファーム インコーポレイテッド 細胞透過性ペプチド変異体およびその用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4426832A1 (en) 2021-11-03 2024-09-11 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Precise genome editing using retrons
WO2023141602A2 (en) 2022-01-21 2023-07-27 Renagade Therapeutics Management Inc. Engineered retrons and methods of use
WO2024044723A1 (en) 2022-08-25 2024-02-29 Renagade Therapeutics Management Inc. Engineered retrons and methods of use
AU2024335327A1 (en) 2023-09-01 2026-03-26 Renagade Therapeutics Management Inc. Gene editing systems, compositions, and methods for treatment of vexas syndrome
WO2025174765A1 (en) 2024-02-12 2025-08-21 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534104A (ja) * 1999-01-12 2002-10-15 サンガモ バイオサイエンシーズ, インコーポレイテッド ジンクフィンガータンパク質を用いた、細胞における、内因性遺伝子発現の調節
JP2003527093A (ja) * 1999-09-14 2003-09-16 サンガモ バイオサイエンシーズ, インコーポレイテッド ジンクフィンガータンパク質を使用する機能遺伝学
WO2004108883A2 (en) * 2003-06-10 2004-12-16 Toolgen, Inc. Transducible dna-binding proteins
JP2004537260A (ja) * 2000-12-07 2004-12-16 サンガモ バイオサイエンシーズ, インコーポレイテッド ジンクフィンガータンパク質による血管新生の調節
WO2004108167A1 (en) * 2003-06-05 2004-12-16 Gencell Sas Plasmid encoding fibroblast growth factor for the treatment of hypercholesterolemia or diabetes associated angiogenic defects
WO2005099771A2 (en) * 2004-04-08 2005-10-27 Sangamo Biosciences, Inc. Methods and compositions for treating neuropathic and neurodegenerative conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693622A (en) * 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US6140466A (en) * 1994-01-18 2000-10-31 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
JP2002502608A (ja) * 1998-02-06 2002-01-29 コラテラル・セラピューティックス・インコーポレイテッド 血管新生促進因子である血管内皮細胞成長因子:vegfの変異体
US7067317B2 (en) * 2000-12-07 2006-06-27 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
US7223740B2 (en) * 2001-05-23 2007-05-29 Fornix Biosciences N.V. Vectors for enhanced expression of VEGF for atrial disease treatment

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534104A (ja) * 1999-01-12 2002-10-15 サンガモ バイオサイエンシーズ, インコーポレイテッド ジンクフィンガータンパク質を用いた、細胞における、内因性遺伝子発現の調節
JP2003527093A (ja) * 1999-09-14 2003-09-16 サンガモ バイオサイエンシーズ, インコーポレイテッド ジンクフィンガータンパク質を使用する機能遺伝学
JP2004537260A (ja) * 2000-12-07 2004-12-16 サンガモ バイオサイエンシーズ, インコーポレイテッド ジンクフィンガータンパク質による血管新生の調節
WO2004108167A1 (en) * 2003-06-05 2004-12-16 Gencell Sas Plasmid encoding fibroblast growth factor for the treatment of hypercholesterolemia or diabetes associated angiogenic defects
WO2004108883A2 (en) * 2003-06-10 2004-12-16 Toolgen, Inc. Transducible dna-binding proteins
WO2005099771A2 (en) * 2004-04-08 2005-10-27 Sangamo Biosciences, Inc. Methods and compositions for treating neuropathic and neurodegenerative conditions

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
AMERICAN JOURNAL OF PHYSIOLOGY, vol. 266, JPN6009051991, 1994, pages 1588 - 1595, ISSN: 0002224862 *
BIOLOGICAL AND PHARMACEUTICAL BULLETIN, vol. 19, no. 4, JPN6012024669, 1996, pages 530 - 535, ISSN: 0002224861 *
CANCER RESEARCH, vol. 63, no. 24, JPN6012024663, 2003, pages 8968 - 8976, ISSN: 0002224858 *
CIRCULATION JOURNAL, vol. 69, no. 1, JPN6012024670, 2005, pages 452, ISSN: 0002224863 *
CIRCULATION, vol. 110, no. 16, JPN6012024661, 2004, pages 2467 - 2475, ISSN: 0002224856 *
CIRCULATION, vol. 97, no. 12, JPN6012024665, 1998, pages 1114 - 1123, ISSN: 0002224859 *
FASEB JOURNAL, vol. [online], JPN6012024672, 19 January 2006 (2006-01-19), pages 10 - 1096, ISSN: 0002224857 *
JOURNAL OF VASCULAR SURGERY, vol. 28, no. 6, JPN6012024667, 1998, pages 964 - 975, ISSN: 0002224860 *
NATURE MEDICINE, vol. 8, no. 12, JPN6012024659, 2002, pages 1427 - 1432, ISSN: 0002224855 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024515250A (ja) * 2021-04-07 2024-04-08 リジェン イノファーム インコーポレイテッド 細胞透過性ペプチド変異体およびその用途
JP7791593B2 (ja) 2021-04-07 2025-12-24 リジェン イノファーム インコーポレイテッド 細胞透過性ペプチド変異体およびその用途

Also Published As

Publication number Publication date
WO2007092609A3 (en) 2008-02-21
US20090305977A1 (en) 2009-12-10
CA2641198A1 (en) 2007-08-16
EP1993586A4 (en) 2009-10-21
EP1993586A2 (en) 2008-11-26
WO2007092609A2 (en) 2007-08-16
AU2007212260A1 (en) 2007-08-16

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