JP2009528344A - インドール誘導体の新規な塩及び医薬におけるその使用 - Google Patents

インドール誘導体の新規な塩及び医薬におけるその使用 Download PDF

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Publication number
JP2009528344A
JP2009528344A JP2008557232A JP2008557232A JP2009528344A JP 2009528344 A JP2009528344 A JP 2009528344A JP 2008557232 A JP2008557232 A JP 2008557232A JP 2008557232 A JP2008557232 A JP 2008557232A JP 2009528344 A JP2009528344 A JP 2009528344A
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Prior art keywords
disease
treatment
indole
ylmethyl
pyridin
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JP2008557232A
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Japanese (ja)
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JP2009528344A5 (OSRAM
Inventor
アンナ−レナ・ベルイ
ラーターン・バート
テスファイ・セブハートゥ
エリカ・ストーレ
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AstraZeneca AB
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AstraZeneca AB
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Publication of JP2009528344A publication Critical patent/JP2009528344A/ja
Publication of JP2009528344A5 publication Critical patent/JP2009528344A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2008557232A 2006-02-28 2007-01-31 インドール誘導体の新規な塩及び医薬におけるその使用 Pending JP2009528344A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77734806P 2006-02-28 2006-02-28
PCT/SE2007/000089 WO2007100282A1 (en) 2006-02-28 2007-01-31 New salts of an indole derivative and their use in medicine

Publications (2)

Publication Number Publication Date
JP2009528344A true JP2009528344A (ja) 2009-08-06
JP2009528344A5 JP2009528344A5 (OSRAM) 2011-02-10

Family

ID=38459317

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008557232A Pending JP2009528344A (ja) 2006-02-28 2007-01-31 インドール誘導体の新規な塩及び医薬におけるその使用

Country Status (5)

Country Link
US (1) US20120115865A1 (OSRAM)
EP (1) EP1991539A4 (OSRAM)
JP (1) JP2009528344A (OSRAM)
CN (1) CN101389623A (OSRAM)
WO (1) WO2007100282A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101851234A (zh) * 2009-04-03 2010-10-06 上海日馨生物科技有限公司 吡咯喹啉醌锂盐衍生物及其制备方法
CN101758337B (zh) 2009-12-03 2012-02-15 湖南阿斯达生化科技有限公司 一种助焊剂用非卤素活性剂
EP3920885A1 (en) 2019-02-08 2021-12-15 Frequency Therapeutics, Inc. Valproic acid compounds and wnt agonists for treating ear disorders

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005027823A2 (en) * 2003-09-24 2005-03-31 Astrazeneca Ab 3-heterocyclyl-indole derivatives as inhibitors of glycogen synthase kinase-3 (gsk-3)
JP2005510457A (ja) * 2001-05-18 2005-04-21 アストラゼネカ・アクチエボラーグ 4−(フェニル−ピペリジン−4−イリデン−メチル)−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
JP2005511532A (ja) * 2001-10-17 2005-04-28 グラクソ グループ リミテッド 5’−カルバモイル−1,1−ビフェニル−4−カルボキサミド誘導体及びそのp38キナーゼ阻害薬としての使用
JP2005519932A (ja) * 2002-02-12 2005-07-07 スミスクライン ビーチャム コーポレーション p38阻害薬として有用なニコチンアミド誘導体
JP2005526814A (ja) * 2002-03-28 2005-09-08 アストラゼネカ・アクチエボラーグ 新規な化合物
JP2005529136A (ja) * 2002-04-24 2005-09-29 メルク エンド カムパニー インコーポレーテッド エストロゲン受容体調節剤
JP2005532348A (ja) * 2002-05-29 2005-10-27 イーライ・リリー・アンド・カンパニー フェニル−チオフェン型ビタミンd受容体調節物資
JP2005535716A (ja) * 2002-08-16 2005-11-24 ファイザー・インク 医薬用の置換グリシン誘導体

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005510457A (ja) * 2001-05-18 2005-04-21 アストラゼネカ・アクチエボラーグ 4−(フェニル−ピペリジン−4−イリデン−メチル)−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
JP2005511532A (ja) * 2001-10-17 2005-04-28 グラクソ グループ リミテッド 5’−カルバモイル−1,1−ビフェニル−4−カルボキサミド誘導体及びそのp38キナーゼ阻害薬としての使用
JP2005519932A (ja) * 2002-02-12 2005-07-07 スミスクライン ビーチャム コーポレーション p38阻害薬として有用なニコチンアミド誘導体
JP2005526814A (ja) * 2002-03-28 2005-09-08 アストラゼネカ・アクチエボラーグ 新規な化合物
JP2005529136A (ja) * 2002-04-24 2005-09-29 メルク エンド カムパニー インコーポレーテッド エストロゲン受容体調節剤
JP2005532348A (ja) * 2002-05-29 2005-10-27 イーライ・リリー・アンド・カンパニー フェニル−チオフェン型ビタミンd受容体調節物資
JP2005535716A (ja) * 2002-08-16 2005-11-24 ファイザー・インク 医薬用の置換グリシン誘導体
WO2005027823A2 (en) * 2003-09-24 2005-03-31 Astrazeneca Ab 3-heterocyclyl-indole derivatives as inhibitors of glycogen synthase kinase-3 (gsk-3)

Also Published As

Publication number Publication date
US20120115865A1 (en) 2012-05-10
CN101389623A (zh) 2009-03-18
EP1991539A4 (en) 2010-08-25
EP1991539A1 (en) 2008-11-19
WO2007100282A1 (en) 2007-09-07
WO2007100282A8 (en) 2008-01-31

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