JP2009528131A5 - - Google Patents
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- JP2009528131A5 JP2009528131A5 JP2008557341A JP2008557341A JP2009528131A5 JP 2009528131 A5 JP2009528131 A5 JP 2009528131A5 JP 2008557341 A JP2008557341 A JP 2008557341A JP 2008557341 A JP2008557341 A JP 2008557341A JP 2009528131 A5 JP2009528131 A5 JP 2009528131A5
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- Prior art keywords
- tissue
- tumor
- agent
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- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003795 chemical substances by application Substances 0.000 claims 14
- 206010028980 Neoplasm Diseases 0.000 claims 13
- 238000004520 electroporation Methods 0.000 claims 9
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 108091030071 RNAI Proteins 0.000 claims 6
- 230000000692 anti-sense effect Effects 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 6
- 230000009368 gene silencing by RNA Effects 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 229920001184 polypeptide Polymers 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108010006654 Bleomycin Proteins 0.000 claims 3
- 102000019034 Chemokines Human genes 0.000 claims 3
- 108010012236 Chemokines Proteins 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 3
- 108090000695 Cytokines Proteins 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 3
- -1 antibody Proteins 0.000 claims 3
- 229960001561 bleomycin Drugs 0.000 claims 3
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 claims 3
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims 3
- 229960004316 cisplatin Drugs 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 229920002643 polyglutamic acid Polymers 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- 230000004565 tumor cell growth Effects 0.000 claims 3
- 230000004614 tumor growth Effects 0.000 claims 3
- 208000007660 Residual Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 230000005540 biological transmission Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 238000002271 resection Methods 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77874006P | 2006-03-03 | 2006-03-03 | |
| PCT/US2007/005133 WO2007103070A2 (en) | 2006-03-03 | 2007-03-02 | Method and device for treating microscopic residual tumors remaining in tissues following surgical resection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013043715A Division JP2013127000A (ja) | 2006-03-03 | 2013-03-06 | 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009528131A JP2009528131A (ja) | 2009-08-06 |
| JP2009528131A5 true JP2009528131A5 (cg-RX-API-DMAC7.html) | 2010-07-15 |
Family
ID=38475369
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008557341A Withdrawn JP2009528131A (ja) | 2006-03-03 | 2007-03-02 | 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置 |
| JP2013043715A Withdrawn JP2013127000A (ja) | 2006-03-03 | 2013-03-06 | 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置 |
| JP2015135937A Active JP6174632B2 (ja) | 2006-03-03 | 2015-07-07 | 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013043715A Withdrawn JP2013127000A (ja) | 2006-03-03 | 2013-03-06 | 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置 |
| JP2015135937A Active JP6174632B2 (ja) | 2006-03-03 | 2015-07-07 | 外科的切除後の組織に残る微視的残余腫瘍の処置方法及び装置 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9037230B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3845269A1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2009528131A (cg-RX-API-DMAC7.html) |
| KR (2) | KR101529448B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN101426550B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007224275B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2644163C (cg-RX-API-DMAC7.html) |
| DK (1) | DK1991303T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2874482T3 (cg-RX-API-DMAC7.html) |
| NO (2) | NO344476B1 (cg-RX-API-DMAC7.html) |
| PL (1) | PL1991303T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007103070A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007103070A2 (en) | 2006-03-03 | 2007-09-13 | Genetronics, Inc. | Method and device for treating microscopic residual tumors remaining in tissues following surgical resection |
| SG183726A1 (en) | 2007-08-14 | 2012-09-27 | Hutchinson Fred Cancer Res | Needle array assembly and method for delivering therapeutic agents |
| US9198733B2 (en) | 2008-04-29 | 2015-12-01 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for electroporation-based therapies |
| US10117707B2 (en) | 2008-04-29 | 2018-11-06 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
| CA2722296A1 (en) | 2008-04-29 | 2009-11-05 | Virginia Tech Intellectual Properties, Inc. | Irreversible electroporation to create tissue scaffolds |
| US10272178B2 (en) | 2008-04-29 | 2019-04-30 | Virginia Tech Intellectual Properties Inc. | Methods for blood-brain barrier disruption using electrical energy |
| US9867652B2 (en) | 2008-04-29 | 2018-01-16 | Virginia Tech Intellectual Properties, Inc. | Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds |
| US11254926B2 (en) | 2008-04-29 | 2022-02-22 | Virginia Tech Intellectual Properties, Inc. | Devices and methods for high frequency electroporation |
| US9283051B2 (en) | 2008-04-29 | 2016-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating a treatment volume for administering electrical-energy based therapies |
| US10448989B2 (en) | 2009-04-09 | 2019-10-22 | Virginia Tech Intellectual Properties, Inc. | High-frequency electroporation for cancer therapy |
| US10702326B2 (en) | 2011-07-15 | 2020-07-07 | Virginia Tech Intellectual Properties, Inc. | Device and method for electroporation based treatment of stenosis of a tubular body part |
| US10238447B2 (en) | 2008-04-29 | 2019-03-26 | Virginia Tech Intellectual Properties, Inc. | System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress |
| US11272979B2 (en) | 2008-04-29 | 2022-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
| US10245098B2 (en) | 2008-04-29 | 2019-04-02 | Virginia Tech Intellectual Properties, Inc. | Acute blood-brain barrier disruption using electrical energy based therapy |
| US8992517B2 (en) | 2008-04-29 | 2015-03-31 | Virginia Tech Intellectual Properties Inc. | Irreversible electroporation to treat aberrant cell masses |
| US9173704B2 (en) * | 2008-06-20 | 2015-11-03 | Angiodynamics, Inc. | Device and method for the ablation of fibrin sheath formation on a venous catheter |
| US8632534B2 (en) | 2009-04-03 | 2014-01-21 | Angiodynamics, Inc. | Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD) |
| US11638603B2 (en) | 2009-04-09 | 2023-05-02 | Virginia Tech Intellectual Properties, Inc. | Selective modulation of intracellular effects of cells using pulsed electric fields |
| US11382681B2 (en) | 2009-04-09 | 2022-07-12 | Virginia Tech Intellectual Properties, Inc. | Device and methods for delivery of high frequency electrical pulses for non-thermal ablation |
| US8903488B2 (en) | 2009-05-28 | 2014-12-02 | Angiodynamics, Inc. | System and method for synchronizing energy delivery to the cardiac rhythm |
| US9895189B2 (en) | 2009-06-19 | 2018-02-20 | Angiodynamics, Inc. | Methods of sterilization and treating infection using irreversible electroporation |
| CA2689400C (en) * | 2009-12-30 | 2023-01-10 | Kenneth W. Adams | Therapeutic agent delivery apparatus and process |
| KR101952155B1 (ko) | 2010-04-28 | 2019-02-26 | 이노비오 파마수티컬즈, 인크. | 구강 점막 전기천공 장치 및 그 용도 |
| EP2627274B1 (en) | 2010-10-13 | 2022-12-14 | AngioDynamics, Inc. | System for electrically ablating tissue of a patient |
| US9457183B2 (en) | 2011-06-15 | 2016-10-04 | Tripep Ab | Injection needle and device |
| US9078665B2 (en) | 2011-09-28 | 2015-07-14 | Angiodynamics, Inc. | Multiple treatment zone ablation probe |
| AU2012328457A1 (en) | 2011-10-28 | 2014-04-24 | Presage Biosciences, Inc. | Methods for drug delivery |
| US9414881B2 (en) | 2012-02-08 | 2016-08-16 | Angiodynamics, Inc. | System and method for increasing a target zone for electrical ablation |
| US10166321B2 (en) | 2014-01-09 | 2019-01-01 | Angiodynamics, Inc. | High-flow port and infusion needle systems |
| CN106715682A (zh) | 2014-05-12 | 2017-05-24 | 弗吉尼亚暨州立大学知识产权公司 | 使用脉冲电场选择性调节细胞的胞内影响 |
| US12114911B2 (en) | 2014-08-28 | 2024-10-15 | Angiodynamics, Inc. | System and method for ablating a tissue site by electroporation with real-time pulse monitoring |
| WO2016100325A1 (en) | 2014-12-15 | 2016-06-23 | Virginia Tech Intellectual Properties, Inc. | Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment |
| US10287543B2 (en) * | 2015-11-19 | 2019-05-14 | Miltenyi Biotec, Gmbh | Process and device for isolating cells from biological tissue |
| US20170232253A1 (en) * | 2016-02-16 | 2017-08-17 | Marcy C. Purnell | Bioelectrodynamics Modulation Method |
| CN114098949B (zh) | 2016-06-27 | 2023-12-19 | 盖能适治疗股份有限公司 | 发生器和具有电极的导管 |
| US12403305B2 (en) | 2016-06-27 | 2025-09-02 | Galvanize Therapeutics, Inc. | Immunostimulation in the treatment of viral infection |
| US10233419B2 (en) | 2016-06-30 | 2019-03-19 | Zymergen Inc. | Apparatuses and methods for electroporation |
| US10905492B2 (en) | 2016-11-17 | 2021-02-02 | Angiodynamics, Inc. | Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode |
| CA3082568A1 (en) | 2017-11-15 | 2019-05-23 | Alcyone Lifesciences, Inc. | Therapy specific, pre-programmed auto injection device |
| EP3710102A4 (en) * | 2017-11-17 | 2021-08-04 | AbbVie Inc. | METHOD OF TREATMENT OF GLIOBLASTOMA |
| US11607537B2 (en) | 2017-12-05 | 2023-03-21 | Virginia Tech Intellectual Properties, Inc. | Method for treating neurological disorders, including tumors, with electroporation |
| CN111683613B (zh) | 2017-12-26 | 2024-05-28 | 盖能适治疗股份有限公司 | 用于各种应用的能量输送的优化 |
| US11311329B2 (en) | 2018-03-13 | 2022-04-26 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for immunotherapy based treatments using non-thermal ablation techniques |
| US11925405B2 (en) | 2018-03-13 | 2024-03-12 | Virginia Tech Intellectual Properties, Inc. | Treatment planning system for immunotherapy enhancement via non-thermal ablation |
| US12390262B2 (en) | 2018-03-13 | 2025-08-19 | Virginia Tech Intellectual Properties, Inc. | Treatment planning system for immunotherapy enhancement via non-thermal ablation |
| TWI850282B (zh) | 2018-11-27 | 2024-08-01 | 香港商弘年發展有限公司 | 用於治療癌症之質體建構體和使用方法 |
| US11950835B2 (en) | 2019-06-28 | 2024-04-09 | Virginia Tech Intellectual Properties, Inc. | Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy |
| JP7586890B2 (ja) | 2019-07-16 | 2024-11-19 | ガルヴァナイズ セラピューティクス，インコーポレイテッド | パルス電界による生殖器の治療 |
| US12214189B2 (en) | 2019-07-24 | 2025-02-04 | Virginia Tech Intellectual Properties, Inc. | Fourier analysis spectroscopy for monitoring tissue impedance changes and treatment outcome during electroporation-based-therapies |
| US12485279B2 (en) | 2020-11-25 | 2025-12-02 | Virginia Tech Intellectual Properties, Inc. | Methods for modulating temporal infrastructure of pulsed electric fields |
| CN116509535B (zh) * | 2023-03-14 | 2024-01-23 | 武汉金柏威光电技术有限公司 | 一种医用高频电刀 |
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| US5747469A (en) * | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
| US5993434A (en) * | 1993-04-01 | 1999-11-30 | Genetronics, Inc. | Method of treatment using electroporation mediated delivery of drugs and genes |
| US5702359A (en) | 1995-06-06 | 1997-12-30 | Genetronics, Inc. | Needle electrodes for mediated delivery of drugs and genes |
| US20030060434A1 (en) | 1997-02-18 | 2003-03-27 | Loretta Nielsen | Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms |
| ATE290403T1 (de) | 1997-06-30 | 2005-03-15 | Roussy Inst Gustave | Verbesserung der verabreichung der nukleinsäure in zellen der plurizellulären eukaryotischen organismen und kombination zur durchführung des verfahrens |
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| WO1999037538A2 (en) | 1998-01-26 | 1999-07-29 | Simula Inc. | Parachute landing velocity attenuator |
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-
2007
- 2007-03-02 WO PCT/US2007/005133 patent/WO2007103070A2/en not_active Ceased
- 2007-03-02 AU AU2007224275A patent/AU2007224275B2/en not_active Ceased
- 2007-03-02 KR KR1020147014055A patent/KR101529448B1/ko active Active
- 2007-03-02 JP JP2008557341A patent/JP2009528131A/ja not_active Withdrawn
- 2007-03-02 EP EP21156169.1A patent/EP3845269A1/en active Pending
- 2007-03-02 KR KR1020087023591A patent/KR101444471B1/ko not_active Expired - Fee Related
- 2007-03-02 PL PL07751865T patent/PL1991303T3/pl unknown
- 2007-03-02 ES ES07751865T patent/ES2874482T3/es active Active
- 2007-03-02 CN CN2007800143130A patent/CN101426550B/zh active Active
- 2007-03-02 US US11/713,181 patent/US9037230B2/en active Active
- 2007-03-02 CA CA2644163A patent/CA2644163C/en active Active
- 2007-03-02 CN CN201210397694.8A patent/CN102921102B/zh active Active
- 2007-03-02 EP EP07751865.2A patent/EP1991303B1/en active Active
- 2007-03-02 DK DK07751865.2T patent/DK1991303T3/da active
-
2008
- 2008-10-01 NO NO20084148A patent/NO344476B1/no unknown
-
2011
- 2011-10-21 US US13/278,721 patent/US20120143120A1/en not_active Abandoned
-
2013
- 2013-03-06 JP JP2013043715A patent/JP2013127000A/ja not_active Withdrawn
-
2015
- 2015-07-07 JP JP2015135937A patent/JP6174632B2/ja active Active
-
2017
- 2017-04-14 US US15/488,288 patent/US11007365B2/en active Active
-
2019
- 2019-09-13 NO NO20191102A patent/NO20191102A1/no not_active Application Discontinuation
-
2021
- 2021-04-20 US US17/235,649 patent/US12324913B2/en active Active
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