JP2009526784A5 - - Google Patents

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Publication number
JP2009526784A5
JP2009526784A5 JP2008554549A JP2008554549A JP2009526784A5 JP 2009526784 A5 JP2009526784 A5 JP 2009526784A5 JP 2008554549 A JP2008554549 A JP 2008554549A JP 2008554549 A JP2008554549 A JP 2008554549A JP 2009526784 A5 JP2009526784 A5 JP 2009526784A5
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Japan
Prior art keywords
graft
hematopoietic stem
bone marrow
patient
use according
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JP2008554549A
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English (en)
Japanese (ja)
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JP5341525B2 (ja
JP2009526784A (ja
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Priority claimed from PCT/US2007/062163 external-priority patent/WO2007095594A2/en
Publication of JP2009526784A publication Critical patent/JP2009526784A/ja
Publication of JP2009526784A5 publication Critical patent/JP2009526784A5/ja
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Publication of JP5341525B2 publication Critical patent/JP5341525B2/ja
Expired - Fee Related legal-status Critical Current
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JP2008554549A 2006-02-14 2007-02-14 造血幹細胞の生着を増強するための方法および組成物 Expired - Fee Related JP5341525B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77340506P 2006-02-14 2006-02-14
US60/773,405 2006-02-14
PCT/US2007/062163 WO2007095594A2 (en) 2006-02-14 2007-02-14 Methods and compositions for enhancing engraftment of hematopoietic stem cells

Publications (3)

Publication Number Publication Date
JP2009526784A JP2009526784A (ja) 2009-07-23
JP2009526784A5 true JP2009526784A5 (enExample) 2010-04-02
JP5341525B2 JP5341525B2 (ja) 2013-11-13

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JP2008554549A Expired - Fee Related JP5341525B2 (ja) 2006-02-14 2007-02-14 造血幹細胞の生着を増強するための方法および組成物

Country Status (8)

Country Link
US (1) US8383095B2 (enExample)
EP (1) EP1984491B1 (enExample)
JP (1) JP5341525B2 (enExample)
CN (1) CN101421393B (enExample)
AU (1) AU2007214468B2 (enExample)
CA (1) CA2642020C (enExample)
IL (1) IL193345A (enExample)
WO (1) WO2007095594A2 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200704252B (en) * 2004-10-25 2009-09-30 Cellerant Therapeutics Inc Methods of expanding myeloid cell populations and uses thereof
JP5924863B2 (ja) 2007-05-06 2016-05-25 スローン ケタリング インスティテュート フォア キャンサー リサーチ Ｇｉ症候群及び移植片対宿主病を治療及び予防する方法
CN102802686A (zh) * 2009-06-18 2012-11-28 Mc2细胞有限责任公司 骨髓胞外基质提取物及其治疗用途
US20130287750A1 (en) * 2009-10-14 2013-10-31 Cellect Biotechnology Ltd. Method of selecting stem cells and uses thereof
JP2013523842A (ja) 2010-04-09 2013-06-17 フレッド ハッチンソン キャンサー リサーチ センター 造血機能を提供するための組成物および方法
CA2795627C (en) 2010-04-09 2023-03-14 Fred Hutchinson Cancer Research Center Compositions and methods for providing hematopoietic function without hla matching
WO2013006806A1 (en) * 2011-07-06 2013-01-10 Cellerant Therapeutics, Inc. Megakaryocyte progenitor cells for production of platelets
EP2788476B1 (en) 2011-12-08 2019-05-22 Fred Hutchinson Cancer Research Center Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells
US9233127B2 (en) * 2012-02-29 2016-01-12 University Of Virginia Patent Foundation Compositions and methods for CXCR4 signaling and umbilical cord blood stem cell engraftment
WO2013155347A1 (en) 2012-04-11 2013-10-17 Izumi Raquel Bruton's tyrosine kinase inhibitors for hematopoietic mobilization
AU2013266069B2 (en) * 2012-05-25 2018-03-15 Sloan Kettering Institute For Cancer Research Methods for treating GI syndrome and graft versus host disease
EP2943566A1 (en) 2013-01-08 2015-11-18 Fred Hutchinson Cancer Research Center Compositions and methods for expansion of embryonic hematopoietic stem cells
EP3054961B1 (en) * 2013-10-09 2020-08-26 Cellect Biotherapeutics Ltd. Activation of hematopoietic progenitors by pretransplant exposure to death ligands
WO2015057992A1 (en) 2013-10-16 2015-04-23 Izumi Raquel Btk inhibitors for hematopoietic mobilization
CN105873952A (zh) 2013-10-31 2016-08-17 弗莱德哈钦森癌症研究中心 经修饰的造血干细胞/祖细胞和非t效应细胞及其用途
WO2016118780A1 (en) 2015-01-21 2016-07-28 Fred Hutchinson Cancer Research Center Point-of-care and/or portable platform for gene therapy
EP3288569A4 (en) 2015-04-29 2018-12-19 Fred Hutchinson Cancer Research Center Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
EP3288570A4 (en) 2015-04-29 2018-11-21 Fred Hutchinson Cancer Research Center Modified stem cells and uses thereof
RU2747728C2 (ru) 2015-12-04 2021-05-13 Фред Хатчинсон Кэнсер Рисерч Сентер Применение размноженных популяций гематопоэтических стволовых клеток/клеток-предшественников
EP3463402B1 (en) * 2016-05-22 2021-06-23 Yeda Research and Development Co. Ltd. Methods of using pulmonary cells for transplantation and induction of tolerance
EP4417210A1 (en) * 2017-03-15 2024-08-21 Orca Biosystems, Inc. Compositions and methods for hematopoietic stem cell transplants
TW201841916A (zh) 2017-04-12 2018-12-01 美商麥珍塔治療學股份有限公司 芳香烴受體拮抗劑及其用途
EP3703715A1 (en) * 2017-10-31 2020-09-09 Magenta Therapeutics, Inc. Compositions and methods for hematopoietic stem and progenitor cell transplant therapy
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
WO2020056170A1 (en) 2018-09-12 2020-03-19 Fred Hutchinson Cancer Research Center Reducing cd33 expression to selectively protect therapeutic cells
US20250135039A1 (en) 2022-02-07 2025-05-01 Ensoma, Inc. Inhibitor-resistant mgmt modifications and modification of mgmt-encoding nucleic acids
EP4338745A1 (en) * 2022-09-14 2024-03-20 Technische Universität Dresden Allogeneic human macrophages for cell therapy

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE81724T1 (de) * 1987-11-09 1992-11-15 Becton Dickinson Co Verfahren zur analyse haematopoietischer zellen in einer probe.
US6852313B1 (en) 1989-10-16 2005-02-08 Amgen Inc. Method of stimulating growth of melanocyte cells by administering stem cell factor
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5840580A (en) * 1990-05-01 1998-11-24 Becton Dickinson And Company Phenotypic characterization of the hematopoietic stem cell
US6326198B1 (en) 1990-06-14 2001-12-04 Regents Of The University Of Michigan Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
SG55145A1 (en) 1992-07-10 1998-12-21 Univ Pittsburgh Hematopoietic facilitatory cells and their uses
US6103522A (en) * 1994-07-20 2000-08-15 Fred Hutchinson Cancer Research Center Human marrow stromal cell lines which sustain hematopoiesis
US5925567A (en) 1995-05-19 1999-07-20 T. Breeders, Inc. Selective expansion of target cell populations
US5877299A (en) * 1995-06-16 1999-03-02 Stemcell Technologies Inc. Methods for preparing enriched human hematopoietic cell preparations
EP0891419A4 (en) * 1996-03-12 2000-03-01 Life Technologies Inc NUTRIENT ADDITIVE FOR HEMATOPOETIC CELL CULTURES
US6335195B1 (en) 1997-01-28 2002-01-01 Maret Corporation Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
WO1999010748A1 (en) 1997-08-21 1999-03-04 Ibiden Co., Ltd. Checker head
US6908763B1 (en) 1997-08-22 2005-06-21 The Board Of Trustees Of The Leland Stanford Junior University Mammalian common lymphoid progenitor cell
AU1585799A (en) * 1997-11-14 1999-06-07 General Hospital Corporation, The Treatment of hematologic disorders
CA2318819A1 (en) 1998-02-05 1999-08-12 Novartis Ag Expanded and genetically modified populations of human hematopoietic stem cells
US6464850B1 (en) 1998-07-31 2002-10-15 Biowhittaker Molecular Applications, Inc. Method for producing hydrophilic monomers and uses thereof
US20030060425A1 (en) * 1998-11-24 2003-03-27 Ahlem Clarence N. Immune modulation method using steroid compounds
WO2000070022A2 (en) 1999-05-14 2000-11-23 City Of Hope Ex vivo expansion of mammalian hematopoietic stem cells
US6761883B2 (en) * 1999-06-29 2004-07-13 The Board Of Trustees Of The Leland Stanford Junior University Mammalian myeloid progenitor cell subsets
CA2375974C (en) 1999-06-29 2010-11-02 The Board Of Trustees Of The Leland Stanford Junior University Mammalian myeloid progenitor cell subsets
EP1248519A4 (en) * 2000-01-18 2004-03-31 Univ Leland Stanford Junior EXPANSION OF STEM AND PROCUREMENT CELLS BY BETA-CATENIN
EP1536688B1 (en) 2002-09-13 2011-12-28 The Board Of Trustees Of The Leland Stanford Junior University Mammalian megakaryocyte progenitor cell
WO2004046312A2 (en) 2002-11-15 2004-06-03 The Board Of Trustees Of The University Of Illinois Methods for in vitro expansion of hematopoietic stem cells
US20040241856A1 (en) * 2003-02-12 2004-12-02 Irm Llc, A Delaware Limited Liability Company Methods and compositions for modulating stem cells
US20050215473A1 (en) * 2003-05-09 2005-09-29 Enrique Alvarez Prophylactic and therapeutic uses of FGF-20 in radiation protection
US20050118147A1 (en) * 2003-11-17 2005-06-02 Il-Hoan Oh Method of using mesenchymal stromal cells to increase engraftment
CN1635113A (zh) * 2003-12-31 2005-07-06 中山大学 从人间质干细胞制备造血干细胞的方法
ZA200704252B (en) * 2004-10-25 2009-09-30 Cellerant Therapeutics Inc Methods of expanding myeloid cell populations and uses thereof
US7811815B2 (en) * 2004-11-15 2010-10-12 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic uses of allogeneic myeloid progenitor cells

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