JP2016517394A5 - - Google Patents
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- JP2016517394A5 JP2016517394A5 JP2015560191A JP2015560191A JP2016517394A5 JP 2016517394 A5 JP2016517394 A5 JP 2016517394A5 JP 2015560191 A JP2015560191 A JP 2015560191A JP 2015560191 A JP2015560191 A JP 2015560191A JP 2016517394 A5 JP2016517394 A5 JP 2016517394A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell composition
- hematopoietic cell
- body weight
- recipient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361769596P | 2013-02-26 | 2013-02-26 | |
| US61/769,596 | 2013-02-26 | ||
| PCT/US2014/015394 WO2014133729A1 (en) | 2013-02-26 | 2014-02-07 | Combined organ and hematopoietic cells for transplantation tolerance of grafts |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016517394A JP2016517394A (ja) | 2016-06-16 |
| JP2016517394A5 true JP2016517394A5 (enExample) | 2017-03-09 |
| JP6305443B2 JP6305443B2 (ja) | 2018-04-04 |
Family
ID=51388802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015560191A Active JP6305443B2 (ja) | 2013-02-26 | 2014-02-07 | 移植片の移植寛容のための組み合わされた臓器及び造血細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (21) | US9504717B2 (enExample) |
| EP (3) | EP3804735A1 (enExample) |
| JP (1) | JP6305443B2 (enExample) |
| KR (2) | KR102491343B1 (enExample) |
| CN (2) | CN113476478A (enExample) |
| AU (2) | AU2014221330B2 (enExample) |
| CA (1) | CA2902098A1 (enExample) |
| GB (2) | GB2526228B (enExample) |
| WO (1) | WO2014133729A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2526228B (en) | 2013-02-26 | 2017-05-03 | Univ Leland Stanford Junior | Combined organ and hematopoietic cells for transplantation tolerance of grafts |
| KR102164405B1 (ko) * | 2013-03-14 | 2020-10-12 | 더 존스 홉킨스 유니버시티 | 나노스케일 인공 항원 제시 세포 |
| US20190000885A1 (en) * | 2015-11-30 | 2019-01-03 | The General Hospital Corporation | Treatment with angiogenin to enhance hematopoietic reconstitution |
| US11273179B2 (en) | 2018-03-12 | 2022-03-15 | Medeor Therapeutics, Inc. | Methods for treating non-cancerous disorders using hematopoietic cells |
| US10842821B2 (en) | 2018-04-05 | 2020-11-24 | Medeor Therapeutics, Inc. | Cellular compositions derived from prior organ donors and methods of manufacture and use thereof |
| US10881692B2 (en) * | 2018-04-05 | 2021-01-05 | Medeor Therapeutics, Inc. | Compositions for establishing mixed chimerism and methods of manufacture thereof |
| WO2020047236A1 (en) * | 2018-08-30 | 2020-03-05 | The Regents Of The University Of California | Mobilization and collection of peripheral blood hematopoietic stem cells from deceased donors |
| US11813376B2 (en) | 2018-09-18 | 2023-11-14 | Medeor Therapeutics, Inc. | Cellular compositions derived from deceased donors to promote graft tolerance and manufacture and uses thereof |
| CN113164517A (zh) * | 2018-09-18 | 2021-07-23 | 梅迪奥治疗学股份有限公司 | 源自死亡供体的用于促进移植物耐受性的细胞组合物及其制造和用途 |
| US11435350B2 (en) | 2018-09-18 | 2022-09-06 | Medeor Therapeutics, Inc. | Methods of analysis of blood from deceased donors |
| US20200086004A1 (en) * | 2018-09-18 | 2020-03-19 | Medeor Therapeutics, Inc. | Methods of making cellular compositions derived from deceased donors to promote graft tolerance |
| WO2020121988A1 (ja) * | 2018-12-09 | 2020-06-18 | 国立大学法人北海道大学 | 免疫抑制作用又は免疫寛容誘導作用を評価する方法、及び免疫寛容誘導剤 |
| JP7395174B2 (ja) * | 2018-12-09 | 2023-12-11 | 国立大学法人北海道大学 | 免疫抑制作用又は免疫寛容誘導作用を評価する方法、及び免疫寛容誘導剤 |
| US11697799B2 (en) | 2019-04-15 | 2023-07-11 | Ossium Health, Inc. | System and method for extraction and cryopreservation of bone marrow |
| US20220305057A1 (en) * | 2019-06-06 | 2022-09-29 | Medeor Therapeutics, Inc. | Methods of making cellular products by post- mortem mobilization and harvesting of hematopoietic cells |
| IL292722A (en) * | 2019-11-05 | 2022-07-01 | Yeda res & development co ltd | Use of veto cells in treatment of t cell mediated autoimmune diseases |
| US20230201256A1 (en) * | 2020-05-21 | 2023-06-29 | Medeor Therapeutics, Inc. | Calcineurin inhibitor to improve cd3+cell survival to thereby facilitate engraftment of donor cd34+ cells in a recipient |
| WO2022020210A1 (en) | 2020-07-18 | 2022-01-27 | Ossium Health, Inc. | Permeation of whole vertebral bodies with a cryoprotectant using vacuum assisted diffusion |
| BR112023005587A2 (pt) * | 2020-09-30 | 2023-05-09 | Univ Leland Stanford Junior | Quimerismo de células hematopoiéticas do doador e transplante de órgãos e tecidos e tolerância autoimune |
| WO2022081909A1 (en) | 2020-10-14 | 2022-04-21 | Ossium Health, Inc. | Systems and methods for extraction and cryopreservation of bone marrow |
| EP4262831A4 (en) * | 2020-12-18 | 2025-01-01 | Ossium Health, Inc. | CELLULAR THERAPY PROCESSES |
| CN112669992B (zh) * | 2020-12-30 | 2024-06-11 | 中国人民解放军总医院 | 单倍体造血干细胞移植atg个体化用药量的计算方法 |
| WO2022159824A1 (en) * | 2021-01-25 | 2022-07-28 | Ossium Health, Inc. | Methods of cell therapies |
| US12245355B2 (en) | 2021-02-19 | 2025-03-04 | Mevion Medical Systems, Inc. | Gantry for a particle therapy system |
| CN113813454B (zh) * | 2021-08-30 | 2022-09-09 | 四川大学华西医院 | 一种采集器官捐献供体血液的方法 |
| WO2023036745A1 (en) * | 2021-09-07 | 2023-03-16 | Zelarion Malta Limited | Method and composition for inducing tolerance |
| US12584107B2 (en) | 2022-01-20 | 2026-03-24 | 3T Biosciences, Inc. | T cell receptor (TCR) compositions and methods for optimizing antigen reactive T-cells |
| EP4633647A1 (en) * | 2022-12-16 | 2025-10-22 | The Regents of the University of California | Retro-active (delayed) immunological tolerance induction in patients with pre-existing solid organ transplants |
| WO2025231133A1 (en) * | 2024-04-30 | 2025-11-06 | University Of Kentucky Research Foundation | GENERATION OF TOLEROGENIC ORGANS USING NORMOTHERMIC or HYPOTHERMIC PERFUSION PUMP WITH TREG CELL BASED IMMUNOTHERAPY WITH OR WITHOUT STEM CELLS |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69723888T2 (de) | 1996-05-09 | 2004-05-27 | The General Hospital Corp., Boston | Gemischter Chimerismus und Toleranz |
| ATE439137T1 (de) | 1997-11-14 | 2009-08-15 | Gen Hospital Corp | Behandlung von hämatologischen störungen |
| CA2319448A1 (en) * | 1998-02-04 | 1999-08-12 | The General Hospital Corporation | Costimulatory blockade and mixed chimerism in allotransplantation |
| AU2980900A (en) | 1999-02-04 | 2000-08-25 | General Hospital Corporation, The | Methods for human allografting |
| WO2001078653A2 (en) * | 2000-04-14 | 2001-10-25 | Millennium Pharmaceuticals, Inc. | Graft rejection inhibition with ccr2 inhibitors |
| JP2002092615A (ja) | 2000-09-20 | 2002-03-29 | Fujitsu Ltd | 画像処理装置及び画像形成装置 |
| AU2002220031A1 (en) * | 2000-11-14 | 2002-05-27 | The University Of Louisville Research Foundation, Inc. | Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc) |
| US20030031652A1 (en) * | 2001-04-16 | 2003-02-13 | Bernhard Hering | Systems and methods for inducing mixed chimerism |
| WO2003012060A2 (en) | 2001-08-01 | 2003-02-13 | Jewish Hospital Healthcare Services, Inc. | Cellular compositions which facilitate engraftment of hematopoietic stem cells while minimizing the risk of gvhd |
| US20060127399A1 (en) * | 2004-09-13 | 2006-06-15 | Defu Zeng | Compositions and methods for inducing chimerism in a subject |
| US7811815B2 (en) | 2004-11-15 | 2010-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic uses of allogeneic myeloid progenitor cells |
| WO2006133450A2 (en) * | 2005-06-08 | 2006-12-14 | Duke University | Anti-cd19 antibody therapy for the transplantation |
| EP2514315A3 (en) * | 2005-08-24 | 2012-11-07 | Yeda Research and Development Co. Ltd. | Universal donor-derived tolerogenic cells for inducing non-syngeneic transplantation tolerance |
| WO2007033221A2 (en) * | 2005-09-13 | 2007-03-22 | The General Hospital Corporation | Methods and compositions for inhibition of immune responses |
| US8632768B2 (en) * | 2008-05-30 | 2014-01-21 | University Of Louisville Research Foundation, Inc. | Human facilitating cells |
| EP3185013B1 (en) * | 2009-12-02 | 2019-10-09 | The Board of Trustees of the Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| US20110137375A1 (en) | 2009-12-03 | 2011-06-09 | Mcbride Keith | System and method for detection of inversion and eversion of the foot using a multi-chamber insole |
| CN103402541A (zh) * | 2011-01-10 | 2013-11-20 | 小利兰·斯坦福大学托管委员会 | 异源造血干细胞移植的增强 |
| WO2013126590A2 (en) * | 2012-02-21 | 2013-08-29 | Baxter International Inc. | Pharmaceutical composition comprising cd34+ cells |
| GB2526228B (en) | 2013-02-26 | 2017-05-03 | Univ Leland Stanford Junior | Combined organ and hematopoietic cells for transplantation tolerance of grafts |
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2014
- 2014-02-07 GB GB1516407.2A patent/GB2526228B/en active Active
- 2014-02-07 KR KR1020217007196A patent/KR102491343B1/ko active Active
- 2014-02-07 US US14/175,832 patent/US9504717B2/en active Active
- 2014-02-07 EP EP20208694.8A patent/EP3804735A1/en not_active Withdrawn
- 2014-02-07 KR KR1020157026288A patent/KR20150132196A/ko not_active Ceased
- 2014-02-07 CN CN202110629293.XA patent/CN113476478A/zh active Pending
- 2014-02-07 US US14/438,159 patent/US9561253B2/en active Active
- 2014-02-07 EP EP26160800.4A patent/EP4729128A2/en active Pending
- 2014-02-07 JP JP2015560191A patent/JP6305443B2/ja active Active
- 2014-02-07 WO PCT/US2014/015394 patent/WO2014133729A1/en not_active Ceased
- 2014-02-07 AU AU2014221330A patent/AU2014221330B2/en active Active
- 2014-02-07 CN CN201480023239.9A patent/CN105188755A/zh active Pending
- 2014-02-07 EP EP14756899.2A patent/EP2961431A4/en not_active Withdrawn
- 2014-02-07 GB GB1704460.3A patent/GB2558680B/en active Active
- 2014-02-07 CA CA2902098A patent/CA2902098A1/en active Pending
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2016
- 2016-10-27 US US15/336,116 patent/US10080769B2/en active Active
- 2016-12-21 US US15/387,292 patent/US9974807B2/en active Active
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2018
- 2018-03-07 US US15/914,736 patent/US10159694B2/en active Active
- 2018-03-07 US US15/914,754 patent/US10183043B2/en active Active
- 2018-03-07 US US15/914,746 patent/US10076542B2/en active Active
- 2018-04-06 US US15/947,285 patent/US10603340B2/en active Active
- 2018-05-01 US US15/968,396 patent/US11040067B2/en active Active
- 2018-08-10 US US16/100,828 patent/US10258648B2/en active Active
- 2018-08-22 US US16/109,373 patent/US10555971B2/en active Active
- 2018-10-16 AU AU2018250369A patent/AU2018250369B2/en active Active
- 2018-11-20 US US16/196,806 patent/US11020428B2/en active Active
- 2018-11-26 US US16/199,599 patent/US11007220B2/en active Active
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2019
- 2019-03-04 US US16/291,492 patent/US11116794B2/en active Active
- 2019-03-04 US US16/291,477 patent/US11129849B2/en active Active
- 2019-06-20 US US16/447,691 patent/US11426429B2/en active Active
- 2019-07-18 US US16/515,955 patent/US11458165B2/en active Active
- 2019-07-18 US US16/515,897 patent/US11439662B2/en active Active
- 2019-12-20 US US16/723,840 patent/US11648264B2/en active Active
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2021
- 2021-03-11 US US17/198,751 patent/US11123367B2/en active Active
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2022
- 2022-07-25 US US17/872,741 patent/US12303532B2/en active Active
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