JP2016517394A5 - - Google Patents
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- JP2016517394A5 JP2016517394A5 JP2015560191A JP2015560191A JP2016517394A5 JP 2016517394 A5 JP2016517394 A5 JP 2016517394A5 JP 2015560191 A JP2015560191 A JP 2015560191A JP 2015560191 A JP2015560191 A JP 2015560191A JP 2016517394 A5 JP2016517394 A5 JP 2016517394A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell composition
- hematopoietic cell
- body weight
- recipient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361769596P | 2013-02-26 | 2013-02-26 | |
| US61/769,596 | 2013-02-26 | ||
| PCT/US2014/015394 WO2014133729A1 (en) | 2013-02-26 | 2014-02-07 | Combined organ and hematopoietic cells for transplantation tolerance of grafts |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016517394A JP2016517394A (ja) | 2016-06-16 |
| JP2016517394A5 true JP2016517394A5 (enExample) | 2017-03-09 |
| JP6305443B2 JP6305443B2 (ja) | 2018-04-04 |
Family
ID=51388802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015560191A Active JP6305443B2 (ja) | 2013-02-26 | 2014-02-07 | 移植片の移植寛容のための組み合わされた臓器及び造血細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (21) | US9504717B2 (enExample) |
| EP (3) | EP3804735A1 (enExample) |
| JP (1) | JP6305443B2 (enExample) |
| KR (2) | KR20150132196A (enExample) |
| CN (2) | CN105188755A (enExample) |
| AU (2) | AU2014221330B2 (enExample) |
| CA (1) | CA2902098A1 (enExample) |
| GB (2) | GB2558680B (enExample) |
| WO (1) | WO2014133729A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6305443B2 (ja) | 2013-02-26 | 2018-04-04 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 移植片の移植寛容のための組み合わされた臓器及び造血細胞 |
| KR102164405B1 (ko) * | 2013-03-14 | 2020-10-12 | 더 존스 홉킨스 유니버시티 | 나노스케일 인공 항원 제시 세포 |
| US20190000885A1 (en) * | 2015-11-30 | 2019-01-03 | The General Hospital Corporation | Treatment with angiogenin to enhance hematopoietic reconstitution |
| WO2019178106A1 (en) * | 2018-03-12 | 2019-09-19 | Medeor Therapeutics, Inc. | Methods for treating non-cancerous disorders using hematopoietic cells |
| US10842821B2 (en) * | 2018-04-05 | 2020-11-24 | Medeor Therapeutics, Inc. | Cellular compositions derived from prior organ donors and methods of manufacture and use thereof |
| US10881692B2 (en) * | 2018-04-05 | 2021-01-05 | Medeor Therapeutics, Inc. | Compositions for establishing mixed chimerism and methods of manufacture thereof |
| WO2020047236A1 (en) * | 2018-08-30 | 2020-03-05 | The Regents Of The University Of California | Mobilization and collection of peripheral blood hematopoietic stem cells from deceased donors |
| US11435350B2 (en) | 2018-09-18 | 2022-09-06 | Medeor Therapeutics, Inc. | Methods of analysis of blood from deceased donors |
| CA3112320A1 (en) * | 2018-09-18 | 2020-03-26 | Medeor Therapeutics, Inc. | Cellular compositions derived from deceased donors to promote graft tolerance and manufacture and uses thereof |
| US11813376B2 (en) | 2018-09-18 | 2023-11-14 | Medeor Therapeutics, Inc. | Cellular compositions derived from deceased donors to promote graft tolerance and manufacture and uses thereof |
| US20200086004A1 (en) * | 2018-09-18 | 2020-03-19 | Medeor Therapeutics, Inc. | Methods of making cellular compositions derived from deceased donors to promote graft tolerance |
| WO2020121988A1 (ja) * | 2018-12-09 | 2020-06-18 | 国立大学法人北海道大学 | 免疫抑制作用又は免疫寛容誘導作用を評価する方法、及び免疫寛容誘導剤 |
| JP7395174B2 (ja) * | 2018-12-09 | 2023-12-11 | 国立大学法人北海道大学 | 免疫抑制作用又は免疫寛容誘導作用を評価する方法、及び免疫寛容誘導剤 |
| US11697799B2 (en) | 2019-04-15 | 2023-07-11 | Ossium Health, Inc. | System and method for extraction and cryopreservation of bone marrow |
| US20220305057A1 (en) * | 2019-06-06 | 2022-09-29 | Medeor Therapeutics, Inc. | Methods of making cellular products by post- mortem mobilization and harvesting of hematopoietic cells |
| JP2023500277A (ja) * | 2019-11-05 | 2023-01-05 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | Ｔ細胞媒介性自己免疫疾患の治療におけるベト細胞の使用 |
| US20230201256A1 (en) * | 2020-05-21 | 2023-06-29 | Medeor Therapeutics, Inc. | Calcineurin inhibitor to improve cd3+cell survival to thereby facilitate engraftment of donor cd34+ cells in a recipient |
| EP4181675A4 (en) | 2020-07-18 | 2024-04-24 | Ossium Health, Inc. | PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION |
| JP2023543863A (ja) * | 2020-09-30 | 2023-10-18 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ドナー造血細胞キメリズム並びに臓器及び組織移植並びに自己免疫寛容 |
| CA3195653A1 (en) * | 2020-10-14 | 2022-04-21 | Ossium Health, Inc. | Systems and methods for extraction and cryopreservation of bone marrow |
| WO2022133282A1 (en) * | 2020-12-18 | 2022-06-23 | Ossium Health, Inc. | Methods of cell therapies |
| CN112669992B (zh) * | 2020-12-30 | 2024-06-11 | 中国人民解放军总医院 | 单倍体造血干细胞移植atg个体化用药量的计算方法 |
| WO2022159824A1 (en) * | 2021-01-25 | 2022-07-28 | Ossium Health, Inc. | Methods of cell therapies |
| JP2024511277A (ja) | 2021-02-19 | 2024-03-13 | メビオン・メディカル・システムズ・インコーポレーテッド | 粒子線治療システムのためのガントリー |
| CN113813454B (zh) * | 2021-08-30 | 2022-09-09 | 四川大学华西医院 | 一种采集器官捐献供体血液的方法 |
| JP2024534926A (ja) * | 2021-09-07 | 2024-09-26 | ゼラリオン マルタ リミテッド | 寛容性を誘導するための方法及び組成物 |
| US12584107B2 (en) | 2022-01-20 | 2026-03-24 | 3T Biosciences, Inc. | T cell receptor (TCR) compositions and methods for optimizing antigen reactive T-cells |
| EP4633647A1 (en) * | 2022-12-16 | 2025-10-22 | The Regents of the University of California | Retro-active (delayed) immunological tolerance induction in patients with pre-existing solid organ transplants |
| WO2025231133A1 (en) * | 2024-04-30 | 2025-11-06 | University Of Kentucky Research Foundation | GENERATION OF TOLEROGENIC ORGANS USING NORMOTHERMIC or HYPOTHERMIC PERFUSION PUMP WITH TREG CELL BASED IMMUNOTHERAPY WITH OR WITHOUT STEM CELLS |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69723888T2 (de) | 1996-05-09 | 2004-05-27 | The General Hospital Corp., Boston | Gemischter Chimerismus und Toleranz |
| AU1585799A (en) | 1997-11-14 | 1999-06-07 | General Hospital Corporation, The | Treatment of hematologic disorders |
| AU748443B2 (en) * | 1998-02-04 | 2002-06-06 | General Hospital Corporation, The | Costimulatory blockade and mixed chimerism in transplantation |
| WO2000045842A2 (en) | 1999-02-04 | 2000-08-10 | The General Hospital Corporation | Methods for human allografting |
| WO2001078653A2 (en) * | 2000-04-14 | 2001-10-25 | Millennium Pharmaceuticals, Inc. | Graft rejection inhibition with ccr2 inhibitors |
| JP2002092615A (ja) | 2000-09-20 | 2002-03-29 | Fujitsu Ltd | 画像処理装置及び画像形成装置 |
| WO2002040640A2 (en) * | 2000-11-14 | 2002-05-23 | The University Of Louisville Research Foundation, Inc. | Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc) |
| US20030031652A1 (en) * | 2001-04-16 | 2003-02-13 | Bernhard Hering | Systems and methods for inducing mixed chimerism |
| WO2003012060A2 (en) * | 2001-08-01 | 2003-02-13 | Jewish Hospital Healthcare Services, Inc. | Cellular compositions which facilitate engraftment of hematopoietic stem cells while minimizing the risk of gvhd |
| US20060127399A1 (en) * | 2004-09-13 | 2006-06-15 | Defu Zeng | Compositions and methods for inducing chimerism in a subject |
| US7811815B2 (en) | 2004-11-15 | 2010-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic uses of allogeneic myeloid progenitor cells |
| JP2008546647A (ja) * | 2005-06-08 | 2008-12-25 | デューク ユニバーシティ | 移植のための抗−ｃｄ１９抗体治療 |
| US8916147B2 (en) | 2005-08-24 | 2014-12-23 | Yeda Research and Devolpment Co. Ltd. | Universal donor-derived tolerogenic cells for inducing non-syngeneic transplantation tolerance |
| WO2007033221A2 (en) * | 2005-09-13 | 2007-03-22 | The General Hospital Corporation | Methods and compositions for inhibition of immune responses |
| US8632768B2 (en) | 2008-05-30 | 2014-01-21 | University Of Louisville Research Foundation, Inc. | Human facilitating cells |
| EP2507630B1 (en) * | 2009-12-02 | 2017-01-25 | The Board of Trustees of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| US20110137375A1 (en) | 2009-12-03 | 2011-06-09 | Mcbride Keith | System and method for detection of inversion and eversion of the foot using a multi-chamber insole |
| CA2823782C (en) * | 2011-01-10 | 2019-05-07 | Samuel Strober | Enhancement of allogeneic hematopoietic stem cell transplantation |
| JP2015508101A (ja) * | 2012-02-21 | 2015-03-16 | バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ | Ｃｄ３４＋細胞を含む薬学的組成物 |
| JP6305443B2 (ja) | 2013-02-26 | 2018-04-04 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 移植片の移植寛容のための組み合わされた臓器及び造血細胞 |
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2014
- 2014-02-07 JP JP2015560191A patent/JP6305443B2/ja active Active
- 2014-02-07 US US14/175,832 patent/US9504717B2/en active Active
- 2014-02-07 EP EP20208694.8A patent/EP3804735A1/en not_active Withdrawn
- 2014-02-07 CN CN201480023239.9A patent/CN105188755A/zh active Pending
- 2014-02-07 KR KR1020157026288A patent/KR20150132196A/ko not_active Ceased
- 2014-02-07 EP EP26160800.4A patent/EP4729128A2/en active Pending
- 2014-02-07 WO PCT/US2014/015394 patent/WO2014133729A1/en not_active Ceased
- 2014-02-07 EP EP14756899.2A patent/EP2961431A4/en not_active Withdrawn
- 2014-02-07 GB GB1704460.3A patent/GB2558680B/en active Active
- 2014-02-07 AU AU2014221330A patent/AU2014221330B2/en active Active
- 2014-02-07 GB GB1516407.2A patent/GB2526228B/en active Active
- 2014-02-07 CA CA2902098A patent/CA2902098A1/en active Pending
- 2014-02-07 KR KR1020217007196A patent/KR102491343B1/ko active Active
- 2014-02-07 CN CN202110629293.XA patent/CN113476478A/zh active Pending
- 2014-02-07 US US14/438,159 patent/US9561253B2/en active Active
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2016
- 2016-10-27 US US15/336,116 patent/US10080769B2/en active Active
- 2016-12-21 US US15/387,292 patent/US9974807B2/en active Active
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2018
- 2018-03-07 US US15/914,736 patent/US10159694B2/en active Active
- 2018-03-07 US US15/914,754 patent/US10183043B2/en active Active
- 2018-03-07 US US15/914,746 patent/US10076542B2/en active Active
- 2018-04-06 US US15/947,285 patent/US10603340B2/en active Active
- 2018-05-01 US US15/968,396 patent/US11040067B2/en active Active
- 2018-08-10 US US16/100,828 patent/US10258648B2/en active Active
- 2018-08-22 US US16/109,373 patent/US10555971B2/en active Active
- 2018-10-16 AU AU2018250369A patent/AU2018250369B2/en active Active
- 2018-11-20 US US16/196,806 patent/US11020428B2/en active Active
- 2018-11-26 US US16/199,599 patent/US11007220B2/en active Active
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2019
- 2019-03-04 US US16/291,477 patent/US11129849B2/en active Active
- 2019-03-04 US US16/291,492 patent/US11116794B2/en active Active
- 2019-06-20 US US16/447,691 patent/US11426429B2/en active Active
- 2019-07-18 US US16/515,897 patent/US11439662B2/en active Active
- 2019-07-18 US US16/515,955 patent/US11458165B2/en active Active
- 2019-12-20 US US16/723,840 patent/US11648264B2/en active Active
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2021
- 2021-03-11 US US17/198,751 patent/US11123367B2/en active Active
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2022
- 2022-07-25 US US17/872,741 patent/US12303532B2/en active Active
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