JP2009526770A - 転移性乳癌の治療 - Google Patents

転移性乳癌の治療 Download PDF

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Publication number
JP2009526770A
JP2009526770A JP2008553685A JP2008553685A JP2009526770A JP 2009526770 A JP2009526770 A JP 2009526770A JP 2008553685 A JP2008553685 A JP 2008553685A JP 2008553685 A JP2008553685 A JP 2008553685A JP 2009526770 A JP2009526770 A JP 2009526770A
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epcam
treatment
dose
patients
low
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JP2008553685A
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English (en)
Japanese (ja)
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カーステン ラインハート
ロバート サラー
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マイクロメット アクツィエン ゲゼルシャフト
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2008553685A 2006-02-09 2007-02-09 転移性乳癌の治療 Pending JP2009526770A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77242106P 2006-02-09 2006-02-09
EP06002680 2006-02-09
PCT/EP2007/001127 WO2007090670A1 (en) 2006-02-09 2007-02-09 Treatment of metastatic breast cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012272352A Division JP2013067645A (ja) 2006-02-09 2012-12-13 転移性乳癌の治療

Publications (1)

Publication Number Publication Date
JP2009526770A true JP2009526770A (ja) 2009-07-23

Family

ID=38110762

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008553685A Pending JP2009526770A (ja) 2006-02-09 2007-02-09 転移性乳癌の治療
JP2012272352A Pending JP2013067645A (ja) 2006-02-09 2012-12-13 転移性乳癌の治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012272352A Pending JP2013067645A (ja) 2006-02-09 2012-12-13 転移性乳癌の治療

Country Status (9)

Country Link
US (3) US7976842B2 (enExample)
EP (1) EP1981539B1 (enExample)
JP (2) JP2009526770A (enExample)
KR (1) KR101296264B1 (enExample)
AU (1) AU2007213920B2 (enExample)
CA (1) CA2638040A1 (enExample)
IL (1) IL192944A0 (enExample)
RU (1) RU2434640C2 (enExample)
WO (1) WO2007090670A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013067645A (ja) * 2006-02-09 2013-04-18 Amgen Research (Munich) Gmbh 転移性乳癌の治療
JP2024073594A (ja) * 2011-05-16 2024-05-29 アイタブメッド (エイチケイ) リミテッド 多重特異性Fab融合タンパク質および使用法
US12460000B2 (en) 2018-09-07 2025-11-04 Itabmed (Hk) Limited Anti-CD19 and anti-CD3 bispecific antigen binding proteins and uses thereof

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
EP2589668A1 (en) 2006-06-14 2013-05-08 Verinata Health, Inc Rare cell analysis using sample splitting and DNA tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
WO2007147074A2 (en) 2006-06-14 2007-12-21 Living Microsystems, Inc. Use of highly parallel snp genotyping for fetal diagnosis
DE102006035617A1 (de) * 2006-07-31 2008-02-21 Siemens Ag Automatische Bestimmung von Tumorlast
US9078888B2 (en) * 2007-01-22 2015-07-14 Gtx, Inc. Nuclear receptor binding agents
US9623021B2 (en) * 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
US9604931B2 (en) 2007-01-22 2017-03-28 Gtx, Inc. Nuclear receptor binding agents
JP5130999B2 (ja) * 2008-03-31 2013-01-30 住友ベークライト株式会社 抗癌剤の有効性予測方法
ES2620294T3 (es) 2008-09-20 2017-06-28 The Board Of Trustees Of The Leland Stanford Junior University Diagnóstico no invasivo de la aneuploidia fetal por secuenciación
WO2011091154A2 (en) * 2010-01-21 2011-07-28 The Regents Of The University Of California Use of human erythrocytes for prevention and treatment of cancer dissemination and growth
BR112013014076A2 (pt) * 2010-12-06 2016-11-22 Cure Cancer Worldwide Corp métodos de direcionamento metabólico de células de câncer usando quimio- e imunotherapia para tratamento de câncer
FR2977674B1 (fr) * 2011-07-06 2015-08-14 Cisbio Bioassays Methode amelioree de detection et/ou de quantification d'un analyte present a la surface d'une cellule
EP2748197A2 (en) 2011-08-26 2014-07-02 Merrimack Pharmaceuticals, Inc. Tandem fc bispecific antibodies
US20130179184A1 (en) * 2012-01-06 2013-07-11 Katherine L. Hurst Individualized Dosing Technique With Multiple Variables
WO2013142390A1 (en) * 2012-03-21 2013-09-26 Gtx, Inc. Aldo-keto reductase subfamily 1c3 (akr1c3) inhibitors
KR102643443B1 (ko) 2012-11-13 2024-03-06 비온테크 에스이 클라우딘 발현 암 질환의 치료제
US9458245B2 (en) 2013-03-06 2016-10-04 Merrimack Pharmaceuticals, Inc. ANTI-C-MET tandem Fc bispecific antibodies
WO2014146672A1 (en) 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2015065505A1 (en) * 2013-10-29 2015-05-07 Duke University Use of cyp27a1 inhibitors, statin, or lxr antagonists alone or in combination with conventional therapy for the treatment of breast cancer
US10975164B2 (en) 2018-02-26 2021-04-13 Emory University Antibodies useful for detection of human carcinoma antigen

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050009097A1 (en) * 2003-03-31 2005-01-13 Better Marc D. Human engineered antibodies to Ep-CAM
WO2005080428A2 (en) * 2004-02-13 2005-09-01 Micromet Ag Anti-epcam immunoglobulins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2194528C2 (ru) * 1996-05-31 2002-12-20 Дзе Скриппс Рисерч Инститьют Способы и композиции, используемые для ингибирования ангиогенеза
RU2188025C2 (ru) * 2000-07-19 2002-08-27 Ростовский научно-исследовательский онкологический институт Способ лечения рака молочной железы
WO2007090670A1 (en) * 2006-02-09 2007-08-16 Micromet Ag Treatment of metastatic breast cancer
PT2520590T (pt) * 2007-04-03 2018-11-14 Amgen Res Munich Gmbh Domínio de ligação específico de espécies cruzadas

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050009097A1 (en) * 2003-03-31 2005-01-13 Better Marc D. Human engineered antibodies to Ep-CAM
WO2005080428A2 (en) * 2004-02-13 2005-09-01 Micromet Ag Anti-epcam immunoglobulins

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN5008024647; PRANG, N., et al.: 'Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against' BRITISH JOURNAL OF CANCER Vol.92, No.2, 20050131, p.342-349 *
JPN5008024648; RAUM, T., et al.: 'Anti-self antibodies selected from a human IgD heavy chain repertoire: a novel approach to generate' CANCER IMMUNOLOGY AND IMMUNOTHERAPY Vol.50, No.3, 200105, p.141-150 *
JPN5008024649; NAUNDORF, S., et al.: 'IN VITRO AND IN VIVO ACTIVITY OF MT201, A FULLY HUMAN MONOCLONAL ANTIBODY FOR PANCARCINOMA TREATMENT' INTERNATIONAL JOURNAL OF CANCER Vol.100, No.1, 2002, p.101-110 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013067645A (ja) * 2006-02-09 2013-04-18 Amgen Research (Munich) Gmbh 転移性乳癌の治療
JP2024073594A (ja) * 2011-05-16 2024-05-29 アイタブメッド (エイチケイ) リミテッド 多重特異性Fab融合タンパク質および使用法
US12460000B2 (en) 2018-09-07 2025-11-04 Itabmed (Hk) Limited Anti-CD19 and anti-CD3 bispecific antigen binding proteins and uses thereof

Also Published As

Publication number Publication date
IL192944A0 (en) 2009-02-11
US20090304716A1 (en) 2009-12-10
EP1981539A1 (en) 2008-10-22
RU2434640C2 (ru) 2011-11-27
US20130177578A1 (en) 2013-07-11
EP1981539B1 (en) 2014-07-23
KR101296264B1 (ko) 2013-08-14
JP2013067645A (ja) 2013-04-18
RU2008130963A (ru) 2010-03-20
AU2007213920A1 (en) 2007-08-16
AU2007213920B2 (en) 2013-08-29
US20120009204A1 (en) 2012-01-12
WO2007090670A1 (en) 2007-08-16
US7976842B2 (en) 2011-07-12
US8337843B2 (en) 2012-12-25
KR20080091817A (ko) 2008-10-14
CA2638040A1 (en) 2007-08-16
US8658172B2 (en) 2014-02-25

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