JP2009526087A - 悪液質の予防および処置のための組成物および方法 - Google Patents
悪液質の予防および処置のための組成物および方法 Download PDFInfo
- Publication number
- JP2009526087A JP2009526087A JP2008555886A JP2008555886A JP2009526087A JP 2009526087 A JP2009526087 A JP 2009526087A JP 2008555886 A JP2008555886 A JP 2008555886A JP 2008555886 A JP2008555886 A JP 2008555886A JP 2009526087 A JP2009526087 A JP 2009526087A
- Authority
- JP
- Japan
- Prior art keywords
- day
- roxithromycin
- agonist
- macrolide
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75311805P | 2005-12-22 | 2005-12-22 | |
| US77275206P | 2006-02-13 | 2006-02-13 | |
| PCT/IB2006/004315 WO2008093148A2 (en) | 2005-12-22 | 2006-12-20 | Compositions and methods for prevention and treatment of cachexia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009526087A true JP2009526087A (ja) | 2009-07-16 |
| JP2009526087A5 JP2009526087A5 (enExample) | 2010-01-07 |
Family
ID=38194678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008555886A Withdrawn JP2009526087A (ja) | 2005-12-22 | 2006-12-20 | 悪液質の予防および処置のための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8080528B2 (enExample) |
| EP (1) | EP1991270A4 (enExample) |
| JP (1) | JP2009526087A (enExample) |
| MX (1) | MX2008007790A (enExample) |
| NO (1) | NO20083240L (enExample) |
| WO (1) | WO2008093148A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000021509A2 (en) * | 1998-10-15 | 2000-04-20 | Imperial College Innovations Limited | Methods of treatment |
| GB0624282D0 (en) | 2006-12-05 | 2007-01-10 | Cavalla David | Treatment of cachexia |
| EP2155180B1 (en) * | 2007-04-24 | 2016-07-13 | Acacia Pharma Limited | Drug combination and its use in the treatment of muscle loss |
| US8252286B2 (en) | 2007-05-21 | 2012-08-28 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
| US9701747B2 (en) | 2007-05-21 | 2017-07-11 | Alderbio Holdings Llc | Method of improving patient survivability and quality of life by anti-IL-6 antibody administration |
| ES2721753T3 (es) | 2007-05-21 | 2019-08-05 | Alderbio Holdings Llc | Anticuerpos contra IL-6 y usos de los mismos |
| US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
| US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
| US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
| US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
| US20090221518A1 (en) * | 2007-11-18 | 2009-09-03 | Anaborex, Inc. | Compositions and Methods for Treatment of Exudative Serous Effusion |
| US8257684B2 (en) * | 2008-03-26 | 2012-09-04 | Neurosigma, Inc. | Methods for identifying and targeting autonomic brain regions |
| JP5620918B2 (ja) * | 2008-11-25 | 2014-11-05 | ブリストル・マイヤーズ スクイブ カンパニー | アルブミンを上昇および/またはcrpを低下させるためのil−6アンタゴニスト |
| US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
| US8992920B2 (en) | 2008-11-25 | 2015-03-31 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of arthritis |
| US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
| US9452227B2 (en) | 2008-11-25 | 2016-09-27 | Alderbio Holdings Llc | Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments |
| US8420089B2 (en) | 2008-11-25 | 2013-04-16 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
| US9212223B2 (en) | 2008-11-25 | 2015-12-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
| WO2011066371A2 (en) | 2009-11-24 | 2011-06-03 | Alder Biopharmaceuticals, Inc. | Antibodies to il-6 and use thereof |
| US9775921B2 (en) | 2009-11-24 | 2017-10-03 | Alderbio Holdings Llc | Subcutaneously administrable composition containing anti-IL-6 antibody |
| WO2012009542A2 (en) * | 2010-07-14 | 2012-01-19 | Kansas State University Research Foundation | Methods for alleviating chronic pain and improving performance of cattle undergoing dehorning or castration |
| WO2012071561A2 (en) | 2010-11-23 | 2012-05-31 | Alder Biopharmaceuticals, Inc. | Anti-il-6 antibodies for the treatment of anemia |
| JP2015512902A (ja) * | 2012-03-28 | 2015-04-30 | アフィボディ・アーベー | 経口投与 |
| WO2020018554A1 (en) * | 2018-07-17 | 2020-01-23 | The Regents Of The University Of California | Methods of treating renal disease |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4859782A (en) * | 1986-06-26 | 1989-08-22 | Harbor Branch Oceanographic Institution, Inc. | Misakinolide compositions and their derivatives |
| EP0662324A1 (en) | 1987-09-15 | 1995-07-12 | The Rowett Research Institute | Use of beta-adrenergic agonists for treating loss of function of striated muscles |
| HUT50044A (en) | 1988-04-12 | 1989-12-28 | Bristol Myers Co | Process for producing pharmaceutical composition comprising megestrol acetate as active ingredient |
| US5252564A (en) * | 1991-03-29 | 1993-10-12 | The United States Of America As Represented By The Secretary Of Agriculture | Method to decrease cortisol secretion by feeding melengesterol acetate |
| CA2194049A1 (en) * | 1994-06-28 | 1996-01-11 | Georgi Stankov | Novel clinical uses of polyene macrolides |
| US5750493A (en) * | 1995-08-30 | 1998-05-12 | Raymond F. Schinazi | Method to improve the biological and antiviral activity of protease inhibitors |
| US6706892B1 (en) * | 1999-09-07 | 2004-03-16 | Conjuchem, Inc. | Pulmonary delivery for bioconjugation |
| US7101576B2 (en) * | 2002-04-12 | 2006-09-05 | Elan Pharma International Limited | Nanoparticulate megestrol formulations |
| US7211568B2 (en) | 2003-12-18 | 2007-05-01 | Kosan Biosciences Incorporated | 9-Desoxoerythromycin compounds as prokinetic agents |
| WO2008004224A2 (en) | 2006-07-03 | 2008-01-10 | Arie Levine | Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders |
-
2006
- 2006-12-20 EP EP06852000A patent/EP1991270A4/en not_active Withdrawn
- 2006-12-20 MX MX2008007790A patent/MX2008007790A/es not_active Application Discontinuation
- 2006-12-20 US US11/614,056 patent/US8080528B2/en not_active Expired - Fee Related
- 2006-12-20 JP JP2008555886A patent/JP2009526087A/ja not_active Withdrawn
- 2006-12-20 WO PCT/IB2006/004315 patent/WO2008093148A2/en not_active Ceased
-
2008
- 2008-07-22 NO NO20083240A patent/NO20083240L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20070149465A1 (en) | 2007-06-28 |
| EP1991270A4 (en) | 2009-12-02 |
| WO2008093148A3 (en) | 2009-04-16 |
| EP1991270A2 (en) | 2008-11-19 |
| NO20083240L (no) | 2008-09-22 |
| MX2008007790A (es) | 2009-03-04 |
| WO2008093148A2 (en) | 2008-08-07 |
| US8080528B2 (en) | 2011-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20090605 |
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| A521 | Request for written amendment filed |
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| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20091110 |
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| A072 | Dismissal of procedure [no reply to invitation to correct request for examination] |
Free format text: JAPANESE INTERMEDIATE CODE: A073 Effective date: 20110315 |
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| A300 | Application deemed to be withdrawn because no request for examination was validly filed |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20110405 |