JP2009525125A5 - - Google Patents
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- Publication number
- JP2009525125A5 JP2009525125A5 JP2008553251A JP2008553251A JP2009525125A5 JP 2009525125 A5 JP2009525125 A5 JP 2009525125A5 JP 2008553251 A JP2008553251 A JP 2008553251A JP 2008553251 A JP2008553251 A JP 2008553251A JP 2009525125 A5 JP2009525125 A5 JP 2009525125A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- segment
- uniform
- copolymer molecules
- polyetheramide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001577 copolymer Polymers 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 5
- 239000004721 Polyphenylene oxide Substances 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 4
- 229920000570 polyether Polymers 0.000 claims 4
- 239000004952 Polyamide Substances 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 229920002647 polyamide Polymers 0.000 claims 3
- 239000011528 polyamide (building material) Substances 0.000 claims 3
- 239000000412 dendrimer Substances 0.000 claims 2
- 229920000736 dendritic polymer Polymers 0.000 claims 2
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims 2
- -1 polytrimethylene Polymers 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 229920001451 Polypropylene glycol Polymers 0.000 claims 1
- 238000006065 biodegradation reaction Methods 0.000 claims 1
- 230000001225 therapeutic Effects 0.000 claims 1
Claims (15)
- 基板、前記基板上に配置のポリマー領域、及び前記ポリマー領域内又は下に配置の治療薬を含む埋め込み可能又は挿入可能な医療器具で、前記ポリマー領域が前記治療薬の前記治療器具からの放除を制御し、ソフトセグメントと均一なハードセグメントをそれぞれ含有する共重合体分子を含む医療器具。
- 前記共重合体分子の少なくとも２５重量％が、均一長さのハードセグメントを有する請求項１に記載の医療器具。
- 前記ポリマー領域がポリエーテルアミド共重合体分子を含み、それぞれがポリエーテルソフトセグメントと均一なポリアミドハードセグメントを含む請求項１に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが複数のポリエーテルセグメントを含む請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、ポリアルキレンオキシド、ポリアルキレンオキシド誘導体、及び上述の物の組み合わせから選ぶポリエーテルセグメントを含む請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、ポリエチレンオキシド、ポリトリメチレンオキシド、ポリプロピレンオキシド、ポリテトラメチレンオキシド、上述の物の誘導体及び上述の物の組み合わせから選ぶポリエーテルセグメントを含む請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、複数の均一なポリアミドセグメントを含む請求項３に記載の医療器具。
- 前記ポリマー領域内のポリエーテルアミド共重合体分子の少なくとも２５重量％がそろいのポリアミドセグメントを有する請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、均一な芳香族ポリエステルアミドセグメントを含む請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、均一なポリアミノ酸セグメントを含む請求項３に記載の医療器具。
- 均一な前記ポリアミノ酸セグメントが芳香族基を含む請求項３に記載の医療器具。
- 均一な前記ポリアミノ酸セグメントが複数の芳香族基を含む請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、均一なポリアミノ酸デンドリマーセグメントを含む請求項３に記載の医療器具。
- 前記ポリエーテルアミド共重合体分子のそれぞれが、デンドリマーセグメントを含む請求項１に記載の医療器具。
- 前記ポリマー領域が、前記共重合体分子に生分解性結合により共有結合した前記治療薬を含む、請求項１に記載の医療器具。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/344,053 | 2006-01-31 | ||
| US11/344,053 US8440214B2 (en) | 2006-01-31 | 2006-01-31 | Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments |
| PCT/US2007/001296 WO2007089435A2 (en) | 2006-01-31 | 2007-01-18 | Medical devices for therapeutic agent delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009525125A JP2009525125A (ja) | 2009-07-09 |
| JP2009525125A5 true JP2009525125A5 (ja) | 2010-03-04 |
| JP5202334B2 JP5202334B2 (ja) | 2013-06-05 |
Family
ID=38229939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008553251A Expired - Fee Related JP5202334B2 (ja) | 2006-01-31 | 2007-01-18 | ソフトセグメントと均一長さのハードセグメントの両者を有する共重合体含有ポリマー領域を持つ治療薬送達用医療器具 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8440214B2 (ja) |
| EP (1) | EP1979014B1 (ja) |
| JP (1) | JP5202334B2 (ja) |
| CA (1) | CA2641457A1 (ja) |
| WO (1) | WO2007089435A2 (ja) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9028859B2 (en) * | 2006-07-07 | 2015-05-12 | Advanced Cardiovascular Systems, Inc. | Phase-separated block copolymer coatings for implantable medical devices |
| CA2673528A1 (en) | 2006-12-20 | 2008-07-24 | Boston Scientific Limited | Stent with a coating for delivering a therapeutic agent |
| MX2009007663A (es) | 2007-01-21 | 2009-10-13 | Hemoteq Ag | Dispositivo medico para el tratamiento de estenosis de pasajes corporales y para la prevencion de reestenosis inminente. |
| US20080306582A1 (en) * | 2007-06-05 | 2008-12-11 | Yunbing Wang | Implantable medical devices with elastomeric copolymer coatings |
| US8202528B2 (en) * | 2007-06-05 | 2012-06-19 | Abbott Cardiovascular Systems Inc. | Implantable medical devices with elastomeric block copolymer coatings |
| US8293260B2 (en) * | 2007-06-05 | 2012-10-23 | Abbott Cardiovascular Systems Inc. | Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices |
| US20090004243A1 (en) | 2007-06-29 | 2009-01-01 | Pacetti Stephen D | Biodegradable triblock copolymers for implantable devices |
| US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
| CA2704032C (en) * | 2007-10-29 | 2016-10-18 | Zimmer, Inc. | Medical implants and methods for delivering biologically active agents |
| AU2008354530B2 (en) * | 2008-04-07 | 2014-02-27 | Indian Institute Of Science | Compositions useful for the treatment of diabetes and other chronic disorder |
| US20090306769A1 (en) * | 2008-06-06 | 2009-12-10 | Boston Scientific Scimed, Inc. | Medical balloon made with hybrid polymer-ceramic material and method of making and using the same |
| US8389083B2 (en) * | 2008-10-17 | 2013-03-05 | Boston Scientific Scimed, Inc. | Polymer coatings with catalyst for medical devices |
| US20100131001A1 (en) * | 2008-11-24 | 2010-05-27 | Medtronic Vascular, Inc. | Targeted Drug Delivery for Aneurysm Treatment |
| IT1394522B1 (it) * | 2009-01-09 | 2012-07-05 | Invatec Technology Ct Gmbh | Dispositivo medicale con rilascio di farmaco |
| EP2421571A2 (en) * | 2009-04-24 | 2012-02-29 | Boston Scientific Scimed, Inc. | Use of drug polymorphs to achieve controlled drug delivery from a coated medical device |
| JP2012532670A (ja) | 2009-07-10 | 2012-12-20 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 薬剤搬送バルーンのためのナノ結晶の使用 |
| WO2011008393A2 (en) * | 2009-07-17 | 2011-01-20 | Boston Scientific Scimed, Inc. | Nucleation of drug delivery balloons to provide improved crystal size and density |
| US8889211B2 (en) | 2010-09-02 | 2014-11-18 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
| US8669360B2 (en) | 2011-08-05 | 2014-03-11 | Boston Scientific Scimed, Inc. | Methods of converting amorphous drug substance into crystalline form |
| US9056152B2 (en) | 2011-08-25 | 2015-06-16 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
| JP6307492B2 (ja) * | 2013-04-01 | 2018-04-04 | テルモ株式会社 | 薬剤投与バルーンカテーテル及びその製造方法 |
| KR101658285B1 (ko) | 2013-08-30 | 2016-09-20 | 주식회사 엘지화학 | 블록 공중합체 |
| WO2015030550A1 (ko) * | 2013-08-30 | 2015-03-05 | 주식회사 엘지화학 | 블록 공중합체 |
| CN116813803B (zh) * | 2023-08-25 | 2023-11-28 | 北京科技大学 | 用于高效装载雷帕霉素的多肽纳米材料及制备方法和应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614549A (en) | 1992-08-21 | 1997-03-25 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
| US6406457B1 (en) | 1994-03-02 | 2002-06-18 | Scimed Life Systems, Inc. | Block copolymer elastomer catheter balloons |
| US6441025B2 (en) | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| AUPO251096A0 (en) * | 1996-09-23 | 1996-10-17 | Cardiac Crc Nominees Pty Limited | Polysiloxane-containing polyurethane elastomeric compositions |
| EP1011744A2 (en) * | 1997-09-17 | 2000-06-28 | Advanced Cardiovascular Systems, Inc. | Polyether block amide catheter balloons |
| HU222543B1 (hu) * | 1998-02-23 | 2003-08-28 | Massachusetts Institute Of Technology | Biológiai úton lebomlani képes emlékező polimerek |
| US6299980B1 (en) * | 1998-09-29 | 2001-10-09 | Medtronic Ave, Inc. | One step lubricious coating |
| US6315790B1 (en) * | 1999-06-07 | 2001-11-13 | Scimed Life Systems, Inc. | Radiopaque marker bands |
| US6620127B2 (en) * | 1999-12-01 | 2003-09-16 | Advanced Cardiovascular Systems, Inc. | Medical device balloon |
| US6716444B1 (en) * | 2000-09-28 | 2004-04-06 | Advanced Cardiovascular Systems, Inc. | Barriers for polymer-coated implantable medical devices and methods for making the same |
| EP1370249A4 (en) | 2001-02-26 | 2006-05-03 | Univ Duke | NEW DENDRITIC POLYMERS AND ITS BIOMEDICAL APPLICATIONS |
| US20020188314A1 (en) * | 2001-06-07 | 2002-12-12 | Microvena Corporation | Radiopaque distal embolic protection device |
| US6585755B2 (en) * | 2001-06-29 | 2003-07-01 | Advanced Cardiovascular | Polymeric stent suitable for imaging by MRI and fluoroscopy |
| US6765069B2 (en) * | 2001-09-28 | 2004-07-20 | Biosurface Engineering Technologies, Inc. | Plasma cross-linked hydrophilic coating |
| US8133501B2 (en) | 2002-02-08 | 2012-03-13 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled drug delivery |
| AU2003206446A1 (en) * | 2002-02-21 | 2003-09-09 | Universiteit Twente | Segmented copolymer containing amide segments |
| US6835387B2 (en) * | 2002-06-11 | 2004-12-28 | Scimed Life Systems, Inc. | Sustained release of superoxide dismutase mimics from implantable or insertable medical devices |
| US8211455B2 (en) | 2002-06-19 | 2012-07-03 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled delivery of a therapeutic agent |
| US8337893B2 (en) * | 2002-07-10 | 2012-12-25 | Florida Research Foundation, Inc, University Of | Sol-gel derived bioactive glass polymer composite |
| CA2494187A1 (en) | 2002-08-13 | 2004-02-19 | Medtronic, Inc. | Active agent delivery system including a polyurethane, medical device, and method |
| US7491234B2 (en) * | 2002-12-03 | 2009-02-17 | Boston Scientific Scimed, Inc. | Medical devices for delivery of therapeutic agents |
| DE10355318A1 (de) * | 2003-11-27 | 2005-06-23 | Wacker-Chemie Gmbh | Verfahren zur Herstellung von organyloxysilylterminierten Polymeren |
| DE102004008202A1 (de) * | 2004-02-18 | 2005-09-01 | Basf Ag | Komposites aus Thermoplasten mit monodispers verteilten Füllstoffen |
| JP4768736B2 (ja) * | 2004-08-13 | 2011-09-07 | レヴァ メディカル、 インコーポレイテッド | 多重使用のための本質的に放射線不透過性の生体吸収性ポリマー |
| US7862835B2 (en) | 2004-10-27 | 2011-01-04 | Boston Scientific Scimed, Inc. | Method of manufacturing a medical device having a porous coating thereon |
| US9125968B2 (en) | 2005-03-30 | 2015-09-08 | Boston Scientific Scimed, Inc. | Polymeric/ceramic composite materials for use in medical devices |
| US7291166B2 (en) * | 2005-05-18 | 2007-11-06 | Advanced Cardiovascular Systems, Inc. | Polymeric stent patterns |
-
2006
- 2006-01-31 US US11/344,053 patent/US8440214B2/en not_active Expired - Fee Related
-
2007
- 2007-01-18 EP EP07762702.4A patent/EP1979014B1/en not_active Not-in-force
- 2007-01-18 JP JP2008553251A patent/JP5202334B2/ja not_active Expired - Fee Related
- 2007-01-18 CA CA002641457A patent/CA2641457A1/en not_active Abandoned
- 2007-01-18 WO PCT/US2007/001296 patent/WO2007089435A2/en active Application Filing
-
2013
- 2013-05-13 US US13/892,720 patent/US20130251778A1/en not_active Abandoned
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