JP2009524692A5 - - Google Patents
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- Publication number
- JP2009524692A5 JP2009524692A5 JP2008552581A JP2008552581A JP2009524692A5 JP 2009524692 A5 JP2009524692 A5 JP 2009524692A5 JP 2008552581 A JP2008552581 A JP 2008552581A JP 2008552581 A JP2008552581 A JP 2008552581A JP 2009524692 A5 JP2009524692 A5 JP 2009524692A5
- Authority
- JP
- Japan
- Prior art keywords
- registered trademark
- ophthalmic formulation
- subject
- tears
- formulation according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 20
- 238000009472 formulation Methods 0.000 claims 12
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 6
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 6
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 3
- 206010013774 Dry eye Diseases 0.000 claims 3
- 229960004384 ketorolac tromethamine Drugs 0.000 claims 3
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 claims 3
- 241001529936 Murinae Species 0.000 claims 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims 2
- 229920005862 polyol Polymers 0.000 claims 2
- 150000003077 polyols Chemical class 0.000 claims 2
- MDKGKXOCJGEUJW-VIFPVBQESA-N (2s)-2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid Chemical compound C1=CC([C@@H](C(O)=O)C)=CC=C1C(=O)C1=CC=CS1 MDKGKXOCJGEUJW-VIFPVBQESA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 206010015946 Eye irritation Diseases 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 229940060237 akwa tears Drugs 0.000 claims 1
- 239000000607 artificial tear Substances 0.000 claims 1
- 229940035183 bion tears Drugs 0.000 claims 1
- 229960003655 bromfenac Drugs 0.000 claims 1
- ZBPLOVFIXSTCRZ-UHFFFAOYSA-N bromfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1 ZBPLOVFIXSTCRZ-UHFFFAOYSA-N 0.000 claims 1
- 229960001631 carbomer Drugs 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 229960001259 diclofenac Drugs 0.000 claims 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 231100000013 eye irritation Toxicity 0.000 claims 1
- 229960003898 flurbiprofen sodium Drugs 0.000 claims 1
- 229920000591 gum Polymers 0.000 claims 1
- 229940030216 hypotears Drugs 0.000 claims 1
- 229960000905 indomethacin Drugs 0.000 claims 1
- 229960004752 ketorolac Drugs 0.000 claims 1
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 229940099374 moisture eyes pm Drugs 0.000 claims 1
- 229940112689 moisture-eyes Drugs 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 229960001002 nepafenac Drugs 0.000 claims 1
- QEFAQIPZVLVERP-UHFFFAOYSA-N nepafenac Chemical compound NC(=O)CC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1N QEFAQIPZVLVERP-UHFFFAOYSA-N 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000012188 paraffin wax Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229940116161 refresh pm Drugs 0.000 claims 1
- GNMBMOULKUXEQF-UHFFFAOYSA-M sodium;2-(3-fluoro-4-phenylphenyl)propanoate;dihydrate Chemical compound O.O.[Na+].FC1=CC(C(C([O-])=O)C)=CC=C1C1=CC=CC=C1 GNMBMOULKUXEQF-UHFFFAOYSA-M 0.000 claims 1
- 229960004492 suprofen Drugs 0.000 claims 1
- 229940080150 systane Drugs 0.000 claims 1
- 229940036266 tears naturale Drugs 0.000 claims 1
- BJORNXNYWNIWEY-UHFFFAOYSA-N tetrahydrozoline hydrochloride Chemical compound Cl.N1CCN=C1C1C2=CC=CC=C2CCC1 BJORNXNYWNIWEY-UHFFFAOYSA-N 0.000 claims 1
- 229960003503 thera tears Drugs 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 229940028445 visine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76194506P | 2006-01-25 | 2006-01-25 | |
| PCT/US2007/061065 WO2007087609A2 (en) | 2006-01-25 | 2007-01-25 | Formulations and methods for treating dry eye |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009524692A JP2009524692A (ja) | 2009-07-02 |
| JP2009524692A5 true JP2009524692A5 (cg-RX-API-DMAC7.html) | 2011-03-17 |
Family
ID=38309951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008552581A Pending JP2009524692A (ja) | 2006-01-25 | 2007-01-25 | ドライアイのための処方物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070254841A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1981491A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009524692A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007208054A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2636646A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007087609A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8512717B2 (en) * | 2003-08-07 | 2013-08-20 | Allergan, Inc. | Compositions for delivery of therapeutics into the eyes and methods for making and using same |
| US8372814B2 (en) * | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
| US8748402B2 (en) | 2004-06-07 | 2014-06-10 | Bausch & Lomb Pharma Holdings Corp. | Ophthalmic formulations and uses thereof |
| US8137111B2 (en) * | 2007-06-28 | 2012-03-20 | Eye Care And Cure Pte. Ltd | Model human eye |
| AU2009202969B1 (en) * | 2009-07-23 | 2009-11-19 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| US9192571B2 (en) * | 2008-03-03 | 2015-11-24 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| US7842714B2 (en) * | 2008-03-03 | 2010-11-30 | Allergan, Inc. | Ketorolac tromethamine compositions for treating ocular pain |
| US8778999B2 (en) * | 2009-03-05 | 2014-07-15 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic compositions |
| PL2586426T3 (pl) | 2009-12-03 | 2016-01-29 | Alcon Res Ltd | Zawiesiny zawierające nanocząsteczkowe polimery karboksywinylowe |
| SI2555770T1 (en) * | 2010-04-09 | 2018-04-30 | Allergan, Inc. | Ketorolac compositions for corneal wound healing |
| US8684743B2 (en) | 2010-07-23 | 2014-04-01 | Eye Care And Cure Pte. Ltd | Model human eye and face manikin for use therewith |
| CN102557976B (zh) * | 2010-12-15 | 2015-06-10 | 辽宁盛京制药有限公司 | 溴芬酸有机盐及其制备方法、其组合物及用途 |
| CN107982211A (zh) * | 2011-04-05 | 2018-05-04 | 奥普托索夫研究与发展有限公司 | 眼科治疗 |
| US20130023575A1 (en) * | 2011-07-22 | 2013-01-24 | Kamran Hosseini | Compositions and methods for the treatment of ocular surface allergies |
| WO2014207769A1 (en) | 2013-06-27 | 2014-12-31 | Mylan Laboratories Ltd | Process for the preparation of nepafenac |
| PT3019177T (pt) | 2013-07-10 | 2020-12-30 | Matrix Biology Inst | Composições de hialuronano de elevada elasticidade e suas utilizações |
| CN109908125A (zh) * | 2013-12-25 | 2019-06-21 | 日本株式会社Ltt生物医药 | 干眼症治疗用滴眼剂 |
| US9775796B1 (en) * | 2014-09-26 | 2017-10-03 | Paul S. Jensen | Dry skin composition and method for preparing the composition |
| ES2871199T3 (es) | 2015-09-24 | 2021-10-28 | Matrix Biology Inst | Composiciones de hialuronano de alta elasticidad y métodos de uso de las mismas |
| KR20240035827A (ko) * | 2021-07-09 | 2024-03-18 | 광저우 오쿠순 옵탈믹 바이오테크놀로지 캄파니 리미티드 | 안구건조증 치료를 위한 약물의 제조에 있어서의 록소프로펜나트륨의 용도 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230724A (en) * | 1979-07-16 | 1980-10-28 | Allergan Pharmaceuticals, Inc. | Method of treating vascularization of the eye with Flurbiprofen |
| US4407791A (en) * | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| US4454151A (en) * | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| DE3612537C1 (de) * | 1986-04-14 | 1987-07-16 | Dispersa Ag | Arzneimittel zur Behandlung von Entzuendungen im Auge |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| CA1325382C (en) * | 1988-01-27 | 1993-12-21 | Takahiro Ogawa | Locally administrable therapeutic composition for inflammatory disease |
| US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
| JPH08503561A (ja) * | 1992-11-27 | 1996-04-16 | シーメンス アクチエンゲゼルシヤフト | モジュールフレームに接続可能な光導体のための差込接続部材 |
| US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
| US5811446A (en) * | 1997-04-18 | 1998-09-22 | Cytos Pharmaceuticals Llc | Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor |
| DK0999825T3 (da) * | 1997-07-29 | 2004-02-09 | Alcon Lab Inc | Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater |
| US6552020B1 (en) * | 1999-07-30 | 2003-04-22 | Allergan, Inc. | Compositions including antibiotics and methods for using same |
| US7128928B2 (en) * | 2002-02-22 | 2006-10-31 | Pharmacia Corporation | Ophthalmic formulation with novel gum composition |
| US6828356B2 (en) * | 2002-07-29 | 2004-12-07 | Ast Products, Inc. | Preparation of ophthalmic compositions |
| US6806364B2 (en) * | 2002-07-29 | 2004-10-19 | Ast Products, Inc. | Ophthalmic compositions |
| PT1586316E (pt) * | 2003-01-21 | 2008-05-28 | Senju Pharma Co | Preparação líquida aquosa contendo ácido 2-amino-3-(4- bromobenzoil)fenilacético |
| US20050239745A1 (en) * | 2004-03-03 | 2005-10-27 | Ophthalmic Research Associates, Inc. | Novel topical ophthalmic formulations |
| WO2005101982A2 (en) * | 2004-03-24 | 2005-11-03 | Sun Pharmaceutical Industries Limited | A stable ophthalmic composition |
| PL1885336T3 (pl) * | 2005-05-10 | 2009-08-31 | Alcon Inc | Kompozycja w postaci zawiesiny zawierająca substancję aktywną, poloksamerowy lub meroksapolowy surfaktant i glikol oraz zastosowanie kompozycji do wytwarzania leku do leczenia chorób oczu |
-
2007
- 2007-01-25 JP JP2008552581A patent/JP2009524692A/ja active Pending
- 2007-01-25 US US11/698,778 patent/US20070254841A1/en not_active Abandoned
- 2007-01-25 AU AU2007208054A patent/AU2007208054A1/en not_active Abandoned
- 2007-01-25 WO PCT/US2007/061065 patent/WO2007087609A2/en not_active Ceased
- 2007-01-25 EP EP07717416A patent/EP1981491A4/en not_active Withdrawn
- 2007-01-25 CA CA002636646A patent/CA2636646A1/en not_active Abandoned
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