JP2009521532A5 - - Google Patents
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- Publication number
- JP2009521532A5 JP2009521532A5 JP2008548581A JP2008548581A JP2009521532A5 JP 2009521532 A5 JP2009521532 A5 JP 2009521532A5 JP 2008548581 A JP2008548581 A JP 2008548581A JP 2008548581 A JP2008548581 A JP 2008548581A JP 2009521532 A5 JP2009521532 A5 JP 2009521532A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- neutral
- composition
- component
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920000642 polymer Polymers 0.000 claims 40
- 230000007935 neutral effect Effects 0.000 claims 29
- 239000000203 mixture Substances 0.000 claims 25
- 239000013543 active substance Substances 0.000 claims 12
- 230000002378 acidificating effect Effects 0.000 claims 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 4
- 229920000954 Polyglycolide Polymers 0.000 claims 4
- 229920000747 poly(lactic acid) Polymers 0.000 claims 4
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 3
- 229940072056 alginate Drugs 0.000 claims 3
- 235000010443 alginic acid Nutrition 0.000 claims 3
- 229920000615 alginic acid Polymers 0.000 claims 3
- 239000012736 aqueous medium Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical class [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 239000004952 Polyamide Substances 0.000 claims 2
- 229920002732 Polyanhydride Polymers 0.000 claims 2
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000003125 aqueous solvent Substances 0.000 claims 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000001814 pectin Substances 0.000 claims 2
- 235000010987 pectin Nutrition 0.000 claims 2
- 229920001277 pectin Polymers 0.000 claims 2
- 229960000292 pectin Drugs 0.000 claims 2
- 229920001308 poly(aminoacid) Polymers 0.000 claims 2
- 229920002647 polyamide Polymers 0.000 claims 2
- 229920000515 polycarbonate Polymers 0.000 claims 2
- 239000004417 polycarbonate Substances 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims 1
- 244000215068 Acacia senegal Species 0.000 claims 1
- 241000416162 Astragalus gummifer Species 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 239000004375 Dextrin Substances 0.000 claims 1
- 229920001353 Dextrin Polymers 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 229920000084 Gum arabic Polymers 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- 229920000161 Locust bean gum Polymers 0.000 claims 1
- 229920001100 Polydextrose Polymers 0.000 claims 1
- 239000004373 Pullulan Substances 0.000 claims 1
- 229920001218 Pullulan Polymers 0.000 claims 1
- 241000288961 Saguinus imperator Species 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 235000015125 Sterculia urens Nutrition 0.000 claims 1
- 240000001058 Sterculia urens Species 0.000 claims 1
- 229920001615 Tragacanth Polymers 0.000 claims 1
- 235000010489 acacia gum Nutrition 0.000 claims 1
- 239000000205 acacia gum Substances 0.000 claims 1
- 239000011149 active material Substances 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 235000019425 dextrin Nutrition 0.000 claims 1
- -1 far celerane Polymers 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- RCRODHONKLSMIF-UHFFFAOYSA-N isosuberenol Natural products O1C(=O)C=CC2=C1C=C(OC)C(CC(O)C(C)=C)=C2 RCRODHONKLSMIF-UHFFFAOYSA-N 0.000 claims 1
- 235000010420 locust bean gum Nutrition 0.000 claims 1
- 239000000711 locust bean gum Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000013856 polydextrose Nutrition 0.000 claims 1
- 239000001259 polydextrose Substances 0.000 claims 1
- 229940035035 polydextrose Drugs 0.000 claims 1
- 235000019423 pullulan Nutrition 0.000 claims 1
- 150000003839 salts Chemical group 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 235000010487 tragacanth Nutrition 0.000 claims 1
- 239000000196 tragacanth Substances 0.000 claims 1
- 229940116362 tragacanth Drugs 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75409205P | 2005-12-27 | 2005-12-27 | |
| PCT/US2006/047927 WO2007075422A2 (en) | 2005-12-27 | 2006-12-14 | Ph modulated films for delivery of actives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009521532A JP2009521532A (ja) | 2009-06-04 |
| JP2009521532A5 true JP2009521532A5 (https=) | 2010-02-12 |
Family
ID=38218457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548581A Pending JP2009521532A (ja) | 2005-12-27 | 2006-12-14 | 活性物質を放出するための、ｐＨ調節されたフィルム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110166240A1 (https=) |
| EP (1) | EP1968558B1 (https=) |
| JP (1) | JP2009521532A (https=) |
| CN (1) | CN101346135A (https=) |
| AU (1) | AU2006329819A1 (https=) |
| CA (1) | CA2631431A1 (https=) |
| ES (1) | ES2624003T3 (https=) |
| WO (1) | WO2007075422A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2952191T (pt) * | 2009-06-12 | 2018-11-30 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
| DK3254676T3 (en) | 2009-10-30 | 2019-03-11 | Ix Biopharma Ltd | QUICK-SOLVING SOLID DOSAGE FORM |
| US12186426B2 (en) | 2009-10-30 | 2025-01-07 | Ix Biopharma Ltd. | Solid dosage form |
| NZ612686A (en) | 2010-12-16 | 2015-11-27 | Cynapsus Therapeutics Inc | Sublingual films |
| AU2014261331B2 (en) * | 2013-05-02 | 2018-02-22 | Cardionovum Gmbh | Balloon surface coating |
| JP7211706B2 (ja) | 2015-04-21 | 2023-01-24 | サノヴィオン ファーマシュティカルズ インコーポレーテッド | 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法 |
| US20170042551A1 (en) | 2015-08-13 | 2017-02-16 | The Brain Protection Company PTY LTD | Implantable damping devices for treating dementia and associated systems and methods of use |
| CN108676085B (zh) * | 2018-07-03 | 2019-09-24 | 北京六盛合医药科技有限公司 | 一种胸腺法新的制备方法及其药物组合物 |
| SG11202100241UA (en) * | 2018-07-11 | 2021-02-25 | Cure Pharmaceutical Holding Corp | Rapidly disintegrating oral film matrix |
| US12208027B2 (en) | 2018-12-04 | 2025-01-28 | The Brain Protection Company PTY LTD | Combinatorial therapies including implantable damping devices and therapeutic agents for treating a condition and associated systems and methods of use |
| US20210130752A1 (en) * | 2019-11-05 | 2021-05-06 | The Procter & Gamble Company | Substrates having water-soluble polymer zones comprising a freshening active and consumer products comprising the same |
| US12490988B2 (en) | 2019-12-16 | 2025-12-09 | The Brain Protection Company PTY LTD | Device and method for altering blood flow characteristics in a vessel |
| CN115534188A (zh) * | 2022-09-21 | 2022-12-30 | 安徽皖维先进功能膜材料研究院有限公司 | 一种聚乙烯醇薄膜的干燥方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3755558A (en) * | 1971-02-23 | 1973-08-28 | Du Pont | Polylactide drug mixtures for topical application atelet aggregation |
| US4950689A (en) * | 1987-03-31 | 1990-08-21 | Yang Robert K | Pectin delivery system |
| JPH09187233A (ja) * | 1996-01-12 | 1997-07-22 | Ota Seiyaku Kk | ゼリー組成物 |
| DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| US6552024B1 (en) * | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
| IL155959A0 (en) * | 2000-11-28 | 2003-12-23 | Fmc Corp | Edible pga (propylene glycol alginate) coating composition |
| US6932861B2 (en) * | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| JP2004099558A (ja) * | 2002-09-11 | 2004-04-02 | Medorekkusu:Kk | 医薬用ゼリー組成物 |
| KR100548925B1 (ko) * | 2002-10-23 | 2006-02-02 | 한미약품 주식회사 | 약물의 경구투여용 서방성 조성물 |
| EP1628643B9 (en) * | 2003-04-14 | 2013-06-12 | Fmc Corporation | Homogeneous, thermoreversible gel film containing kappa-2 carrageenan and soft capsules made therefrom |
| JPWO2005011637A1 (ja) * | 2003-08-04 | 2006-09-14 | エーザイ株式会社 | 用時分散型製剤 |
| US7470397B2 (en) * | 2003-10-24 | 2008-12-30 | Adhesives Research, Inc. | Disintegratable films for diagnostic devices |
| JP4413665B2 (ja) * | 2004-03-19 | 2010-02-10 | 救急薬品工業株式会社 | 口腔内粘膜フィルム剤 |
| KR100598326B1 (ko) * | 2004-04-10 | 2006-07-10 | 한미약품 주식회사 | ＨＭＧ-ＣｏＡ 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법 |
-
2006
- 2006-12-14 JP JP2008548581A patent/JP2009521532A/ja active Pending
- 2006-12-14 CN CNA2006800490292A patent/CN101346135A/zh active Pending
- 2006-12-14 ES ES06845545.0T patent/ES2624003T3/es active Active
- 2006-12-14 AU AU2006329819A patent/AU2006329819A1/en not_active Abandoned
- 2006-12-14 CA CA002631431A patent/CA2631431A1/en not_active Abandoned
- 2006-12-14 WO PCT/US2006/047927 patent/WO2007075422A2/en not_active Ceased
- 2006-12-14 EP EP06845545.0A patent/EP1968558B1/en active Active
-
2011
- 2011-03-21 US US13/052,615 patent/US20110166240A1/en not_active Abandoned
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