JP2009521532A5 - - Google Patents
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- Publication number
- JP2009521532A5 JP2009521532A5 JP2008548581A JP2008548581A JP2009521532A5 JP 2009521532 A5 JP2009521532 A5 JP 2009521532A5 JP 2008548581 A JP2008548581 A JP 2008548581A JP 2008548581 A JP2008548581 A JP 2008548581A JP 2009521532 A5 JP2009521532 A5 JP 2009521532A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- neutral
- composition
- component
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920000642 polymer Polymers 0.000 claims 40
- 230000007935 neutral effect Effects 0.000 claims 29
- 239000000203 mixture Substances 0.000 claims 25
- 239000013543 active substance Substances 0.000 claims 12
- 230000002378 acidificating effect Effects 0.000 claims 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 4
- 229920000954 Polyglycolide Polymers 0.000 claims 4
- 229920000747 poly(lactic acid) Polymers 0.000 claims 4
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 3
- 229940072056 alginate Drugs 0.000 claims 3
- 235000010443 alginic acid Nutrition 0.000 claims 3
- 229920000615 alginic acid Polymers 0.000 claims 3
- 239000012736 aqueous medium Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical class [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 239000004952 Polyamide Substances 0.000 claims 2
- 229920002732 Polyanhydride Polymers 0.000 claims 2
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000003125 aqueous solvent Substances 0.000 claims 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000001814 pectin Substances 0.000 claims 2
- 235000010987 pectin Nutrition 0.000 claims 2
- 229920001277 pectin Polymers 0.000 claims 2
- 229960000292 pectin Drugs 0.000 claims 2
- 229920001308 poly(aminoacid) Polymers 0.000 claims 2
- 229920002647 polyamide Polymers 0.000 claims 2
- 229920000515 polycarbonate Polymers 0.000 claims 2
- 239000004417 polycarbonate Substances 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims 1
- 244000215068 Acacia senegal Species 0.000 claims 1
- 241000416162 Astragalus gummifer Species 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 239000004375 Dextrin Substances 0.000 claims 1
- 229920001353 Dextrin Polymers 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 229920000084 Gum arabic Polymers 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- 229920000161 Locust bean gum Polymers 0.000 claims 1
- 229920001100 Polydextrose Polymers 0.000 claims 1
- 239000004373 Pullulan Substances 0.000 claims 1
- 229920001218 Pullulan Polymers 0.000 claims 1
- 241000288961 Saguinus imperator Species 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 235000015125 Sterculia urens Nutrition 0.000 claims 1
- 240000001058 Sterculia urens Species 0.000 claims 1
- 229920001615 Tragacanth Polymers 0.000 claims 1
- 235000010489 acacia gum Nutrition 0.000 claims 1
- 239000000205 acacia gum Substances 0.000 claims 1
- 239000011149 active material Substances 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 235000019425 dextrin Nutrition 0.000 claims 1
- -1 far celerane Polymers 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- RCRODHONKLSMIF-UHFFFAOYSA-N isosuberenol Natural products O1C(=O)C=CC2=C1C=C(OC)C(CC(O)C(C)=C)=C2 RCRODHONKLSMIF-UHFFFAOYSA-N 0.000 claims 1
- 235000010420 locust bean gum Nutrition 0.000 claims 1
- 239000000711 locust bean gum Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000013856 polydextrose Nutrition 0.000 claims 1
- 239000001259 polydextrose Substances 0.000 claims 1
- 229940035035 polydextrose Drugs 0.000 claims 1
- 235000019423 pullulan Nutrition 0.000 claims 1
- 150000003839 salts Chemical group 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 235000010487 tragacanth Nutrition 0.000 claims 1
- 239000000196 tragacanth Substances 0.000 claims 1
- 229940116362 tragacanth Drugs 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75409205P | 2005-12-27 | 2005-12-27 | |
| PCT/US2006/047927 WO2007075422A2 (en) | 2005-12-27 | 2006-12-14 | Ph modulated films for delivery of actives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009521532A JP2009521532A (ja) | 2009-06-04 |
| JP2009521532A5 true JP2009521532A5 (https=) | 2010-02-12 |
Family
ID=38218457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548581A Pending JP2009521532A (ja) | 2005-12-27 | 2006-12-14 | 活性物質を放出するための、ｐＨ調節されたフィルム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110166240A1 (https=) |
| EP (1) | EP1968558B1 (https=) |
| JP (1) | JP2009521532A (https=) |
| CN (1) | CN101346135A (https=) |
| AU (1) | AU2006329819A1 (https=) |
| CA (1) | CA2631431A1 (https=) |
| ES (1) | ES2624003T3 (https=) |
| WO (1) | WO2007075422A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2699077T3 (es) * | 2009-06-12 | 2019-02-07 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
| US12186426B2 (en) | 2009-10-30 | 2025-01-07 | Ix Biopharma Ltd. | Solid dosage form |
| DK2493457T3 (en) | 2009-10-30 | 2017-10-02 | Ix Biopharma Ltd | QUICK-SOLVING SOLID DOSAGE FORM |
| PT2651357T (pt) | 2010-12-16 | 2020-06-17 | Sunovion Pharmaceuticals Inc | Películas sublinguais |
| CN104394898B (zh) * | 2013-05-02 | 2017-10-13 | 卡迪奥诺沃姆有限公司 | 球囊表面涂层 |
| EP4578461A3 (en) | 2015-04-21 | 2025-09-03 | Sumitomo Pharma America, Inc. | Methods of treating parkinsons disease by administration of apomorphine to an oral mucosa |
| US20170042551A1 (en) | 2015-08-13 | 2017-02-16 | The Brain Protection Company PTY LTD | Implantable damping devices for treating dementia and associated systems and methods of use |
| CN108676085B (zh) * | 2018-07-03 | 2019-09-24 | 北京六盛合医药科技有限公司 | 一种胸腺法新的制备方法及其药物组合物 |
| KR20230165867A (ko) * | 2018-07-11 | 2023-12-05 | 큐어 파마슈티컬 인코포레이티드 | 신속 붕해 경구 필름 매트릭스 |
| CN113727658A (zh) | 2018-12-04 | 2021-11-30 | 脑部保护私人有限公司 | 包括用于治疗病症的可植入阻尼装置和治疗剂的组合疗法及相关系统和使用方法 |
| US20210130752A1 (en) * | 2019-11-05 | 2021-05-06 | The Procter & Gamble Company | Substrates having water-soluble polymer zones comprising a freshening active and consumer products comprising the same |
| WO2021119737A1 (en) | 2019-12-16 | 2021-06-24 | The Brain Protection Company PTY LTD | A device and method for altering blood flow characteristics in a vessel |
| CN115534188A (zh) * | 2022-09-21 | 2022-12-30 | 安徽皖维先进功能膜材料研究院有限公司 | 一种聚乙烯醇薄膜的干燥方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3755558A (en) * | 1971-02-23 | 1973-08-28 | Du Pont | Polylactide drug mixtures for topical application atelet aggregation |
| US4950689A (en) * | 1987-03-31 | 1990-08-21 | Yang Robert K | Pectin delivery system |
| JPH09187233A (ja) * | 1996-01-12 | 1997-07-22 | Ota Seiyaku Kk | ゼリー組成物 |
| DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| US6552024B1 (en) * | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
| US6932861B2 (en) * | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| BR0115585A (pt) * | 2000-11-28 | 2005-12-13 | Fmc Corp | Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento |
| JP2004099558A (ja) * | 2002-09-11 | 2004-04-02 | Medorekkusu:Kk | 医薬用ゼリー組成物 |
| KR100548925B1 (ko) * | 2002-10-23 | 2006-02-02 | 한미약품 주식회사 | 약물의 경구투여용 서방성 조성물 |
| JP2007525451A (ja) * | 2003-04-14 | 2007-09-06 | エフ エム シー コーポレーション | 均一かつ熱可逆性アルギネートフィルムの伝達システム |
| JPWO2005011637A1 (ja) * | 2003-08-04 | 2006-09-14 | エーザイ株式会社 | 用時分散型製剤 |
| WO2005039499A2 (en) * | 2003-10-24 | 2005-05-06 | Adhesives Research, Inc. | Rapidly disintegrating film |
| JP4413665B2 (ja) * | 2004-03-19 | 2010-02-10 | 救急薬品工業株式会社 | 口腔内粘膜フィルム剤 |
| KR100598326B1 (ko) * | 2004-04-10 | 2006-07-10 | 한미약품 주식회사 | ＨＭＧ-ＣｏＡ 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법 |
-
2006
- 2006-12-14 CN CNA2006800490292A patent/CN101346135A/zh active Pending
- 2006-12-14 ES ES06845545.0T patent/ES2624003T3/es active Active
- 2006-12-14 JP JP2008548581A patent/JP2009521532A/ja active Pending
- 2006-12-14 WO PCT/US2006/047927 patent/WO2007075422A2/en not_active Ceased
- 2006-12-14 EP EP06845545.0A patent/EP1968558B1/en active Active
- 2006-12-14 AU AU2006329819A patent/AU2006329819A1/en not_active Abandoned
- 2006-12-14 CA CA002631431A patent/CA2631431A1/en not_active Abandoned
-
2011
- 2011-03-21 US US13/052,615 patent/US20110166240A1/en not_active Abandoned
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