JP2009520822A - コルチコステロイドを送達するための方法およびシステム - Google Patents

コルチコステロイドを送達するための方法およびシステム Download PDF

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Publication number
JP2009520822A
JP2009520822A JP2008547497A JP2008547497A JP2009520822A JP 2009520822 A JP2009520822 A JP 2009520822A JP 2008547497 A JP2008547497 A JP 2008547497A JP 2008547497 A JP2008547497 A JP 2008547497A JP 2009520822 A JP2009520822 A JP 2009520822A
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JP
Japan
Prior art keywords
cyclodextrin
composition
nebulizer
administration
corticosteroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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JP2008547497A
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English (en)
Japanese (ja)
Inventor
マルコム アール． ヒル，
Original Assignee
ティカ レーケメデル アーベー
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Publication date
Application filed by ティカ レーケメデル アーベー filed Critical ティカ レーケメデル アーベー
Publication of JP2009520822A publication Critical patent/JP2009520822A/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2008547497A 2005-12-20 2006-12-19 コルチコステロイドを送達するための方法およびシステム Withdrawn JP2009520822A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US75233205P 2005-12-20 2005-12-20
US75276505P 2005-12-20 2005-12-20
US75273505P 2005-12-20 2005-12-20
US77399906P 2006-02-15 2006-02-15
US77399806P 2006-02-15 2006-02-15
US82009406P 2006-07-21 2006-07-21
US82009206P 2006-07-21 2006-07-21
US82009606P 2006-07-21 2006-07-21
PCT/US2006/048630 WO2007075800A2 (fr) 2005-12-20 2006-12-19 Méthodes et systèmes d'administration de corticostéroïdes

Publications (1)

Publication Number Publication Date
JP2009520822A true JP2009520822A (ja) 2009-05-28

Family

ID=38218568

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2008547580A Withdrawn JP2009520828A (ja) 2005-12-20 2006-12-19 コルチコステロイドを送達するためのシステムおよび方法
JP2008547497A Withdrawn JP2009520822A (ja) 2005-12-20 2006-12-19 コルチコステロイドを送達するための方法およびシステム
JP2008547498A Withdrawn JP2009520823A (ja) 2005-12-20 2006-12-19 薬物動態学的プロフィールの向上を有するコルチコステロイドを送達するための方法およびシステム
JP2008547534A Withdrawn JP2009520827A (ja) 2005-12-20 2006-12-19 肺内沈着の増大を有するコルチコステロイドを送達するためのシステムおよび方法
JP2008547495A Withdrawn JP2009520821A (ja) 2005-12-20 2006-12-19 肺内沈着の増大を有するコルチコステロイドを送達するための方法およびシステム
JP2008547496A Withdrawn JP2009524590A (ja) 2005-12-20 2006-12-19 薬物動態学的プロフィールの向上を有するコルチコステロイドを送達するための方法およびシステム

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2008547580A Withdrawn JP2009520828A (ja) 2005-12-20 2006-12-19 コルチコステロイドを送達するためのシステムおよび方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2008547498A Withdrawn JP2009520823A (ja) 2005-12-20 2006-12-19 薬物動態学的プロフィールの向上を有するコルチコステロイドを送達するための方法およびシステム
JP2008547534A Withdrawn JP2009520827A (ja) 2005-12-20 2006-12-19 肺内沈着の増大を有するコルチコステロイドを送達するためのシステムおよび方法
JP2008547495A Withdrawn JP2009520821A (ja) 2005-12-20 2006-12-19 肺内沈着の増大を有するコルチコステロイドを送達するための方法およびシステム
JP2008547496A Withdrawn JP2009524590A (ja) 2005-12-20 2006-12-19 薬物動態学的プロフィールの向上を有するコルチコステロイドを送達するための方法およびシステム

Country Status (5)

Country Link
EP (6) EP1971349A2 (fr)
JP (6) JP2009520828A (fr)
BR (1) BRPI0620225A2 (fr)
CA (2) CA2634398A1 (fr)
WO (6) WO2007075801A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
JP5473931B2 (ja) * 2007-11-16 2014-04-16 パーティクル・メージャーリング・システムズ・インコーポレーテッド 光学粒子計数器を較正検証するためのシステム及び方法
AR073796A1 (es) * 2008-10-10 2010-12-01 Schering Corp Formulaciones de corticosteroides y sus metodos de tratamiento
WO2015109201A1 (fr) * 2014-01-17 2015-07-23 Nephron Pharmaceuticals Corporation Formulation de cyclodextrine-budésonide
BR112016022405A2 (pt) * 2014-03-28 2017-08-15 Univ Liege Composições de ciclodextrina e derivado de budesonida e métodos
EP2923702A1 (fr) * 2014-03-28 2015-09-30 Universite De Liege Composition de cyclodextrine avec des dérivés de budésonide pour le traitement et la prévention d'une maladie inflammatoire pulmonaire
WO2019217286A1 (fr) 2018-05-07 2019-11-14 Prana Biosciences Inc Formulations de métaxalone
CN113490691A (zh) 2019-01-03 2021-10-08 劣势者药物有限公司 环糊精二聚体、其组合物及其用途
CN113491677B (zh) * 2020-03-18 2023-09-26 南京知和医药科技有限公司 一类药用抗病毒药物吸入剂新型制剂及制备方法
WO2022217029A1 (fr) * 2021-04-09 2022-10-13 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions et procédés d'administration d'agents pharmaceutiques

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
US20020183292A1 (en) * 2000-10-31 2002-12-05 Michel Pairet Pharmaceutical compositions based on anticholinergics and corticosteroids
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
EP1373258B1 (fr) * 2001-01-31 2005-09-28 Pfizer Products Inc. Ether derivatives useful as inhibitors of pde4 isozymes
CA2441744C (fr) * 2001-03-20 2011-07-12 Cydex, Inc. Preparation contenant du propofol et de la cyclodextrine d'ether sulfoalkylique
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US7244742B2 (en) * 2002-08-17 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co Kg Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic
DK1585548T3 (en) * 2002-12-09 2018-09-03 Abraxis Bioscience Llc COMPOSITIONS AND PROCEDURES FOR THE DELIVERY OF PHARMACOLOGICAL AGENTS
US20050065141A1 (en) * 2003-07-31 2005-03-24 Odink Debra A. Carbapenems useful in treating and preventing pulmonary infections, pharmaceutical compositions thereof and modes of administration thereof
AU2004292445B2 (en) * 2003-11-21 2010-02-04 Zalicus Inc. Methods and reagents for the treatment of inflammatory disorders
AU2004312096A1 (en) * 2003-12-31 2005-07-21 Cydex Pharmaceuticals, Inc. Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid

Also Published As

Publication number Publication date
EP1971348A2 (fr) 2008-09-24
JP2009520821A (ja) 2009-05-28
WO2007075799A3 (fr) 2009-01-15
WO2007075798A3 (fr) 2008-11-20
WO2007075963A2 (fr) 2007-07-05
WO2007075799A2 (fr) 2007-07-05
WO2007075798A2 (fr) 2007-07-05
EP1973550A2 (fr) 2008-10-01
WO2007075800A3 (fr) 2008-11-20
EP1971346A2 (fr) 2008-09-24
WO2007075859A3 (fr) 2008-12-11
WO2007075798A9 (fr) 2007-08-23
WO2007075800A2 (fr) 2007-07-05
WO2007075801A3 (fr) 2008-12-31
WO2007075859A2 (fr) 2007-07-05
CA2634413A1 (fr) 2007-07-05
JP2009524590A (ja) 2009-07-02
JP2009520828A (ja) 2009-05-28
EP1971345A2 (fr) 2008-09-24
BRPI0620225A2 (pt) 2011-11-01
EP1971347A2 (fr) 2008-09-24
CA2634398A1 (fr) 2007-07-05
JP2009520827A (ja) 2009-05-28
WO2007075801A2 (fr) 2007-07-05
WO2007075963A3 (fr) 2008-11-27
JP2009520823A (ja) 2009-05-28
EP1971349A2 (fr) 2008-09-24

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