BRPI0620225A2 - métodos e sistemas para a distribuição de corticosteróides tendo um perfil farmacocinético aumentado - Google Patents

métodos e sistemas para a distribuição de corticosteróides tendo um perfil farmacocinético aumentado Download PDF

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Publication number
BRPI0620225A2
BRPI0620225A2 BRPI0620225-0A BRPI0620225A BRPI0620225A2 BR PI0620225 A2 BRPI0620225 A2 BR PI0620225A2 BR PI0620225 A BRPI0620225 A BR PI0620225A BR PI0620225 A2 BRPI0620225 A2 BR PI0620225A2
Authority
BR
Brazil
Prior art keywords
cyclodextrin
corticosteroid
dose
nebulizer
inhalation mixture
Prior art date
Application number
BRPI0620225-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Malcolm
Hill R.
Original Assignee
Tika Läkemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tika Läkemedel Ab filed Critical Tika Läkemedel Ab
Publication of BRPI0620225A2 publication Critical patent/BRPI0620225A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0620225-0A 2005-12-20 2006-12-19 métodos e sistemas para a distribuição de corticosteróides tendo um perfil farmacocinético aumentado BRPI0620225A2 (pt)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US75276505P 2005-12-20 2005-12-20
US75233205P 2005-12-20 2005-12-20
US75273505P 2005-12-20 2005-12-20
US60/752.765 2005-12-20
US60/752.332 2005-12-20
US60/752.735 2005-12-20
US77399806P 2006-02-15 2006-02-15
US77399906P 2006-02-15 2006-02-15
US60/773.998 2006-02-15
US60/773.999 2006-02-15
US82009206P 2006-07-21 2006-07-21
US82009606P 2006-07-21 2006-07-21
US82009406P 2006-07-21 2006-07-21
US60/820.094 2006-07-21
US60/820.092 2006-07-21
US60/820.096 2006-07-21
PCT/US2006/048629 WO2007075799A2 (fr) 2005-12-20 2006-12-19 Méthodes et systèmes d'administration de corticostéroïdes présentant un meilleur profil pharmacocinétique

Publications (1)

Publication Number Publication Date
BRPI0620225A2 true BRPI0620225A2 (pt) 2011-11-01

Family

ID=38218568

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0620225-0A BRPI0620225A2 (pt) 2005-12-20 2006-12-19 métodos e sistemas para a distribuição de corticosteróides tendo um perfil farmacocinético aumentado

Country Status (5)

Country Link
EP (6) EP1971345A2 (fr)
JP (6) JP2009524590A (fr)
BR (1) BRPI0620225A2 (fr)
CA (2) CA2634398A1 (fr)
WO (6) WO2007075859A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CN101911139B (zh) * 2007-11-16 2013-03-20 粒子监测系统有限公司 用于光学粒子计数器的校准验证的系统和方法
EP2349206A2 (fr) * 2008-10-10 2011-08-03 Schering Corporation Compositions à base de corticoïdes et procédés de traitement associés
JP2017503029A (ja) * 2014-01-17 2017-01-26 ネフロン ファーマシューティカルズ コーポレーションＮｅｐｈｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｏｒｐｏｒａｔｉｏｎ ブデソニドシクロデキストリン処方物
DK3151836T3 (da) * 2014-03-28 2023-04-03 Univ Liege Sammensætning omfattende cyclodextrin og budesonidderivater til anvendelse til behandling og profylakse af lungeinflammationer
EP2923702A1 (fr) * 2014-03-28 2015-09-30 Universite De Liege Composition de cyclodextrine avec des dérivés de budésonide pour le traitement et la prévention d'une maladie inflammatoire pulmonaire
US11672781B2 (en) 2018-05-07 2023-06-13 Prana Biosciences Inc Metaxalone formulations
CN113490691A (zh) 2019-01-03 2021-10-08 劣势者药物有限公司 环糊精二聚体、其组合物及其用途
CN113491677B (zh) * 2020-03-18 2023-09-26 南京知和医药科技有限公司 一类药用抗病毒药物吸入剂新型制剂及制备方法
US20240189244A1 (en) * 2021-04-09 2024-06-13 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for delivering pharmaceutical agents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
US20020183292A1 (en) * 2000-10-31 2002-12-05 Michel Pairet Pharmaceutical compositions based on anticholinergics and corticosteroids
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
IL156460A0 (en) * 2001-01-31 2004-01-04 Pfizer Prod Inc Ether derivatives useful as inhibitors of pde4 isozymes
EP1383445A4 (fr) * 2001-03-20 2005-04-13 Cydex Inc Preparation contenant du propofol et de la cyclodextrine d'ether sulfoalkylique
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US7244742B2 (en) * 2002-08-17 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co Kg Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic
AU2003299590B8 (en) * 2002-12-09 2010-04-08 Abraxis Bioscience, Llc Compositions and methods of delivery of pharmacological agents
US20050065141A1 (en) * 2003-07-31 2005-03-24 Odink Debra A. Carbapenems useful in treating and preventing pulmonary infections, pharmaceutical compositions thereof and modes of administration thereof
EP1689390B1 (fr) * 2003-11-21 2011-02-09 Zalicus Inc. Procedes et reactifs destines au traitement de troubles inflammatoires
NZ548225A (en) * 2003-12-31 2012-12-21 Cydex Pharmaceuticals Inc Inhalant formulation containing sulfoakyl ether cyclodextrin and corticosteroid

Also Published As

Publication number Publication date
JP2009524590A (ja) 2009-07-02
WO2007075799A3 (fr) 2009-01-15
WO2007075799A2 (fr) 2007-07-05
EP1971345A2 (fr) 2008-09-24
EP1971349A2 (fr) 2008-09-24
WO2007075859A3 (fr) 2008-12-11
WO2007075800A2 (fr) 2007-07-05
JP2009520821A (ja) 2009-05-28
JP2009520823A (ja) 2009-05-28
WO2007075859A2 (fr) 2007-07-05
WO2007075798A9 (fr) 2007-08-23
EP1973550A2 (fr) 2008-10-01
CA2634398A1 (fr) 2007-07-05
EP1971348A2 (fr) 2008-09-24
JP2009520822A (ja) 2009-05-28
WO2007075800A3 (fr) 2008-11-20
EP1971346A2 (fr) 2008-09-24
JP2009520827A (ja) 2009-05-28
WO2007075798A3 (fr) 2008-11-20
JP2009520828A (ja) 2009-05-28
CA2634413A1 (fr) 2007-07-05
WO2007075963A2 (fr) 2007-07-05
WO2007075798A2 (fr) 2007-07-05
WO2007075963A3 (fr) 2008-11-27
WO2007075801A3 (fr) 2008-12-31
EP1971347A2 (fr) 2008-09-24
WO2007075801A2 (fr) 2007-07-05

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired