JP2009519949A - 肥満症および関連する代謝性疾患の治療のための組成物および方法 - Google Patents
肥満症および関連する代謝性疾患の治療のための組成物および方法 Download PDFInfo
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- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
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- LLDXOPKUNJTIRF-QFIPXVFZSA-N solabegron Chemical compound C([C@H](O)C=1C=C(Cl)C=CC=1)NCCNC(C=1)=CC=CC=1C1=CC=CC(C(O)=O)=C1 LLDXOPKUNJTIRF-QFIPXVFZSA-N 0.000 description 1
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- YSMODUONRAFBET-WHFBIAKZSA-N threo-5-hydroxy-L-lysine Chemical compound NC[C@@H](O)CC[C@H](N)C(O)=O YSMODUONRAFBET-WHFBIAKZSA-N 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
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- BJBUEDPLEOHJGE-IMJSIDKUSA-N trans-3-hydroxy-L-proline Chemical compound O[C@H]1CC[NH2+][C@@H]1C([O-])=O BJBUEDPLEOHJGE-IMJSIDKUSA-N 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
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- XPFJYKARVSSRHE-UHFFFAOYSA-K trisodium;2-hydroxypropane-1,2,3-tricarboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].[Na+].[Na+].OC(=O)CC(O)(C(O)=O)CC(O)=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O XPFJYKARVSSRHE-UHFFFAOYSA-K 0.000 description 1
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75141205P | 2005-12-16 | 2005-12-16 | |
| PCT/US2006/047953 WO2007075439A2 (en) | 2005-12-16 | 2006-12-15 | Compositions and methods for treating obesity and related metabolic disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009519949A true JP2009519949A (ja) | 2009-05-21 |
| JP2009519949A5 JP2009519949A5 (https=) | 2010-01-21 |
Family
ID=38218466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545850A Pending JP2009519949A (ja) | 2005-12-16 | 2006-12-15 | 肥満症および関連する代謝性疾患の治療のための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090209460A1 (https=) |
| EP (1) | EP1973953A2 (https=) |
| JP (1) | JP2009519949A (https=) |
| AU (1) | AU2006329836A1 (https=) |
| CA (1) | CA2634016A1 (https=) |
| WO (1) | WO2007075439A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
| EP2049081B1 (en) | 2006-08-09 | 2012-11-14 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| EP2120985B1 (en) | 2007-02-05 | 2012-06-27 | Amylin Pharmaceuticals, Inc. | FN-38 peptides for use in the treatment of psychotic and anxiety disorders |
| HRP20130259T1 (hr) | 2007-04-23 | 2013-04-30 | Intarcia Therapeutics, Inc. | Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe |
| WO2009046848A1 (en) * | 2007-09-11 | 2009-04-16 | Mondobiotech Laboratories Ag | Use of the peptide thymosin beta 4 alone or in combination with cecropin a as a therapeutic agent |
| KR20100057642A (ko) * | 2007-09-11 | 2010-05-31 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 ｃｎｐ-２２ 단독 또는 피살라에민과 배합된 이의 용도 |
| DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
| WO2010116752A1 (ja) * | 2009-04-08 | 2010-10-14 | 武田薬品工業株式会社 | ニューロメジンｕ誘導体 |
| EP2427475B1 (en) * | 2009-05-08 | 2020-11-04 | Techfields Biochem Co., Ltd. | High penetration prodrug compositions of peptides and peptide-related compounds |
| SMT201700583T1 (it) | 2009-09-28 | 2018-01-11 | Intarcia Therapeutics Inc | Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario |
| JP2013209295A (ja) | 2010-10-13 | 2013-10-10 | Takeda Chem Ind Ltd | ペプチド誘導体 |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| US10925639B2 (en) | 2015-06-03 | 2021-02-23 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| RU2760007C2 (ru) | 2016-05-16 | 2021-11-22 | Интарсия Терапьютикс, Инк. | Полипептиды, селективные к рецепторам глюкагона, и способы их применения |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
| US12161694B2 (en) | 2017-03-24 | 2024-12-10 | The Broad Institute, Inc. | Methods and compositions for regulating innate lymphoid cell inflammatory responses |
| EP4648849A1 (en) | 2023-01-12 | 2025-11-19 | Boehringer Ingelheim International GmbH | Nmu receptor 2 agonists |
| WO2026013210A1 (en) | 2024-07-11 | 2026-01-15 | Boehringer Ingelheim International Gmbh | Novel nmu receptor 2 agonists |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001081418A1 (en) * | 2000-04-27 | 2001-11-01 | Merck & Co., Inc. | New neuromedin u receptor nmur2 and nucleotides encoding it |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002265497A (ja) * | 2001-03-12 | 2002-09-18 | Tadashi Hashimoto | 生理活性ペプチドニューロメジンｕの高活性誘導体 |
| US8076288B2 (en) * | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| JP5317318B2 (ja) * | 2004-12-24 | 2013-10-16 | 武田薬品工業株式会社 | 新規ポリペプチドおよびその用途 |
| EP2330124B1 (en) * | 2005-08-11 | 2015-02-25 | Amylin Pharmaceuticals, LLC | Hybrid polypeptides with selectable properties |
| EP2120985B1 (en) * | 2007-02-05 | 2012-06-27 | Amylin Pharmaceuticals, Inc. | FN-38 peptides for use in the treatment of psychotic and anxiety disorders |
-
2006
- 2006-12-15 CA CA002634016A patent/CA2634016A1/en not_active Abandoned
- 2006-12-15 AU AU2006329836A patent/AU2006329836A1/en not_active Abandoned
- 2006-12-15 US US12/097,737 patent/US20090209460A1/en not_active Abandoned
- 2006-12-15 JP JP2008545850A patent/JP2009519949A/ja active Pending
- 2006-12-15 EP EP06845564A patent/EP1973953A2/en not_active Withdrawn
- 2006-12-15 WO PCT/US2006/047953 patent/WO2007075439A2/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001081418A1 (en) * | 2000-04-27 | 2001-11-01 | Merck & Co., Inc. | New neuromedin u receptor nmur2 and nucleotides encoding it |
Non-Patent Citations (1)
| Title |
|---|
| JPN6012019959; Ａｍｉｎｏ Ａｃｉｄｓ． ２００３， Ｖｏｌ．２５， Ｎｏ．１， ｐ．１０７-１１０ * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1973953A2 (en) | 2008-10-01 |
| US20090209460A1 (en) | 2009-08-20 |
| WO2007075439A2 (en) | 2007-07-05 |
| AU2006329836A1 (en) | 2007-07-05 |
| CA2634016A1 (en) | 2007-07-05 |
| WO2007075439A3 (en) | 2007-12-06 |
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