JP2009519949A - 肥満症および関連する代謝性疾患の治療のための組成物および方法 - Google Patents

肥満症および関連する代謝性疾患の治療のための組成物および方法 Download PDF

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JP2009519949A
JP2009519949A JP2008545850A JP2008545850A JP2009519949A JP 2009519949 A JP2009519949 A JP 2009519949A JP 2008545850 A JP2008545850 A JP 2008545850A JP 2008545850 A JP2008545850 A JP 2008545850A JP 2009519949 A JP2009519949 A JP 2009519949A
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peptide
fnx
nmx
polypeptide
subject
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JP2008545850A
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Japanese (ja)
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JP2009519949A5 (https=
Inventor
アンドリュー・エイ・ヤング
サラ・エル・マックエイド
リチャード・ピットナー
ベド・スリバスタバ
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Richard Pittner
Sarah L Mcquaid
Amylin Pharmaceuticals LLC
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Richard Pittner
Sarah L Mcquaid
Amylin Pharmaceuticals LLC
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Application filed by Richard Pittner, Sarah L Mcquaid, Amylin Pharmaceuticals LLC filed Critical Richard Pittner
Publication of JP2009519949A publication Critical patent/JP2009519949A/ja
Publication of JP2009519949A5 publication Critical patent/JP2009519949A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
JP2008545850A 2005-12-16 2006-12-15 肥満症および関連する代謝性疾患の治療のための組成物および方法 Pending JP2009519949A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75141205P 2005-12-16 2005-12-16
PCT/US2006/047953 WO2007075439A2 (en) 2005-12-16 2006-12-15 Compositions and methods for treating obesity and related metabolic disorders

Publications (2)

Publication Number Publication Date
JP2009519949A true JP2009519949A (ja) 2009-05-21
JP2009519949A5 JP2009519949A5 (https=) 2010-01-21

Family

ID=38218466

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008545850A Pending JP2009519949A (ja) 2005-12-16 2006-12-15 肥満症および関連する代謝性疾患の治療のための組成物および方法

Country Status (6)

Country Link
US (1) US20090209460A1 (https=)
EP (1) EP1973953A2 (https=)
JP (1) JP2009519949A (https=)
AU (1) AU2006329836A1 (https=)
CA (1) CA2634016A1 (https=)
WO (1) WO2007075439A2 (https=)

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US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
EP2359808B1 (en) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
US8309522B2 (en) 2007-02-05 2012-11-13 Amylin Pharmaceuticals, Llc Neuromedin and FN-38 peptides for treating psychiatric diseases
WO2008133908A2 (en) 2007-04-23 2008-11-06 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
JP2010539002A (ja) * 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト ウロジラチンの治療剤としての使用
WO2009033690A1 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Bfgf (119-126) for therapeutic applications
CA2726861C (en) * 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
CA2758264A1 (en) * 2009-04-08 2010-10-14 Takeda Pharmaceutical Company Limited Neuromedin u derivative
PL2427475T3 (pl) * 2009-05-08 2021-07-19 Techfields Biochem Co., Ltd. Kompozycje proleku o wysokim przenikaniu peptydów i związków powiązanych z peptydami
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
JP2013209295A (ja) 2010-10-13 2013-10-10 Takeda Chem Ind Ltd ペプチド誘導体
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
RU2730996C2 (ru) 2015-06-03 2020-08-26 Интарсия Терапьютикс, Инк. Системы установки и извлечения имплантата
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
JP7286542B2 (ja) 2017-01-03 2023-06-05 インターシア セラピューティクス，インコーポレイティド Ｇｌｐ－１受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
WO2018175924A1 (en) 2017-03-24 2018-09-27 The Broad Institute, Inc. Methods and compositions for regulating innate lymphoid cell inflammatory responses
WO2024149820A1 (en) 2023-01-12 2024-07-18 Boehringer Ingelheim International Gmbh Nmu receptor 2 agonists
WO2026013210A1 (en) 2024-07-11 2026-01-15 Boehringer Ingelheim International Gmbh Novel nmu receptor 2 agonists

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081418A1 (en) * 2000-04-27 2001-11-01 Merck & Co., Inc. New neuromedin u receptor nmur2 and nucleotides encoding it

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002265497A (ja) * 2001-03-12 2002-09-18 Tadashi Hashimoto 生理活性ペプチドニューロメジンｕの高活性誘導体
US8076288B2 (en) * 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
EP1829969B1 (en) * 2004-12-24 2012-11-28 National Cerebral and Cardiovascular Center Novel polypeptide and the use thereof
WO2007022123A2 (en) * 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
US8309522B2 (en) * 2007-02-05 2012-11-13 Amylin Pharmaceuticals, Llc Neuromedin and FN-38 peptides for treating psychiatric diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081418A1 (en) * 2000-04-27 2001-11-01 Merck & Co., Inc. New neuromedin u receptor nmur2 and nucleotides encoding it

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6012019959; Ａｍｉｎｏ　Ａｃｉｄｓ．　２００３，　Ｖｏｌ．２５，　Ｎｏ．１，　ｐ．１０７-１１０ *

Also Published As

Publication number Publication date
AU2006329836A1 (en) 2007-07-05
WO2007075439A2 (en) 2007-07-05
CA2634016A1 (en) 2007-07-05
EP1973953A2 (en) 2008-10-01
WO2007075439A3 (en) 2007-12-06
US20090209460A1 (en) 2009-08-20

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