CA2634016A1 - Compositions and methods for treating obesity and related metabolic disorders - Google Patents

Compositions and methods for treating obesity and related metabolic disorders Download PDF

Info

Publication number
CA2634016A1
CA2634016A1 CA002634016A CA2634016A CA2634016A1 CA 2634016 A1 CA2634016 A1 CA 2634016A1 CA 002634016 A CA002634016 A CA 002634016A CA 2634016 A CA2634016 A CA 2634016A CA 2634016 A1 CA2634016 A1 CA 2634016A1
Authority
CA
Canada
Prior art keywords
peptide
polypeptide
des
fnx
nmx
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002634016A
Other languages
English (en)
French (fr)
Inventor
Andrew A. Young
Sarah L. Mcquaid
Richard Pittner
Ved Srivastava
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amylin Pharmaceuticals LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2634016A1 publication Critical patent/CA2634016A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
CA002634016A 2005-12-16 2006-12-15 Compositions and methods for treating obesity and related metabolic disorders Abandoned CA2634016A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75141205P 2005-12-16 2005-12-16
US60/751,412 2005-12-16
PCT/US2006/047953 WO2007075439A2 (en) 2005-12-16 2006-12-15 Compositions and methods for treating obesity and related metabolic disorders

Publications (1)

Publication Number Publication Date
CA2634016A1 true CA2634016A1 (en) 2007-07-05

Family

ID=38218466

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002634016A Abandoned CA2634016A1 (en) 2005-12-16 2006-12-15 Compositions and methods for treating obesity and related metabolic disorders

Country Status (6)

Country Link
US (1) US20090209460A1 (https=)
EP (1) EP1973953A2 (https=)
JP (1) JP2009519949A (https=)
AU (1) AU2006329836A1 (https=)
CA (1) CA2634016A1 (https=)
WO (1) WO2007075439A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
MX2008014870A (es) 2006-05-30 2009-02-12 Intarcia Therapeutics Inc Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas.
EP2049081B1 (en) 2006-08-09 2012-11-14 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
EP2120985B1 (en) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 peptides for use in the treatment of psychotic and anxiety disorders
HRP20130259T1 (hr) 2007-04-23 2013-04-30 Intarcia Therapeutics, Inc. Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe
WO2009046848A1 (en) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Use of the peptide thymosin beta 4 alone or in combination with cecropin a as a therapeutic agent
KR20100057642A (ko) * 2007-09-11 2010-05-31 몬도바이오테크 래보래토리즈 아게 치료제로서의 cnp-22 단독 또는 피살라에민과 배합된 이의 용도
DK2240155T3 (da) 2008-02-13 2012-09-17 Intarcia Therapeutics Inc Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
WO2010116752A1 (ja) * 2009-04-08 2010-10-14 武田薬品工業株式会社 ニューロメジンu誘導体
EP2427475B1 (en) * 2009-05-08 2020-11-04 Techfields Biochem Co., Ltd. High penetration prodrug compositions of peptides and peptide-related compounds
SMT201700583T1 (it) 2009-09-28 2018-01-11 Intarcia Therapeutics Inc Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario
JP2013209295A (ja) 2010-10-13 2013-10-10 Takeda Chem Ind Ltd ペプチド誘導体
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
RU2760007C2 (ru) 2016-05-16 2021-11-22 Интарсия Терапьютикс, Инк. Полипептиды, селективные к рецепторам глюкагона, и способы их применения
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
US12161694B2 (en) 2017-03-24 2024-12-10 The Broad Institute, Inc. Methods and compositions for regulating innate lymphoid cell inflammatory responses
EP4648849A1 (en) 2023-01-12 2025-11-19 Boehringer Ingelheim International GmbH Nmu receptor 2 agonists
WO2026013210A1 (en) 2024-07-11 2026-01-15 Boehringer Ingelheim International Gmbh Novel nmu receptor 2 agonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2407458A1 (en) * 2000-04-27 2001-11-01 Merck & Co., Inc. New neuromedin u receptor nmur2 and nucleotides encoding it
JP2002265497A (ja) * 2001-03-12 2002-09-18 Tadashi Hashimoto 生理活性ペプチドニューロメジンuの高活性誘導体
US8076288B2 (en) * 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
JP5317318B2 (ja) * 2004-12-24 2013-10-16 武田薬品工業株式会社 新規ポリペプチドおよびその用途
EP2330124B1 (en) * 2005-08-11 2015-02-25 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
EP2120985B1 (en) * 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 peptides for use in the treatment of psychotic and anxiety disorders

Also Published As

Publication number Publication date
EP1973953A2 (en) 2008-10-01
US20090209460A1 (en) 2009-08-20
JP2009519949A (ja) 2009-05-21
WO2007075439A2 (en) 2007-07-05
AU2006329836A1 (en) 2007-07-05
WO2007075439A3 (en) 2007-12-06

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20121217