JP2009517403A5 - - Google Patents

Download PDF

Info

Publication number
JP2009517403A5
JP2009517403A5 JP2008542534A JP2008542534A JP2009517403A5 JP 2009517403 A5 JP2009517403 A5 JP 2009517403A5 JP 2008542534 A JP2008542534 A JP 2008542534A JP 2008542534 A JP2008542534 A JP 2008542534A JP 2009517403 A5 JP2009517403 A5 JP 2009517403A5
Authority
JP
Japan
Prior art keywords
parp
analog
inhibitor
composition
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008542534A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009517403A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/061254 external-priority patent/WO2007062413A2/en
Publication of JP2009517403A publication Critical patent/JP2009517403A/ja
Publication of JP2009517403A5 publication Critical patent/JP2009517403A5/ja
Pending legal-status Critical Current

Links

JP2008542534A 2005-11-25 2006-11-27 Parp−1阻害剤の使用 Pending JP2009517403A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73953605P 2005-11-25 2005-11-25
PCT/US2006/061254 WO2007062413A2 (en) 2005-11-25 2006-11-27 Use of parp-1 inhibitors

Publications (2)

Publication Number Publication Date
JP2009517403A JP2009517403A (ja) 2009-04-30
JP2009517403A5 true JP2009517403A5 (https=) 2010-01-14

Family

ID=38068066

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008542534A Pending JP2009517403A (ja) 2005-11-25 2006-11-27 Parp−1阻害剤の使用

Country Status (9)

Country Link
US (1) US20090170860A1 (https=)
EP (1) EP1962843B1 (https=)
JP (1) JP2009517403A (https=)
AT (1) ATE499098T1 (https=)
AU (1) AU2006318226A1 (https=)
CA (1) CA2630900A1 (https=)
DE (1) DE602006020335D1 (https=)
ES (1) ES2361566T3 (https=)
WO (1) WO2007062413A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164077A (en) * 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
EP1365808B1 (en) * 2000-11-06 2011-01-19 Pharma Mar, S.A. Compositions for antitumour treatment containing ecteinascidin 743
GB0117402D0 (en) * 2001-07-17 2001-09-05 Pharma Mar Sa New antitumoral derivatives of et-743
CA2545054A1 (en) * 2003-11-14 2005-06-02 Pharma Mar, S.A. Combination therapy comprising the use of et-743 and paclitaxel for treating cancer
DK1827500T3 (da) * 2004-10-26 2009-08-31 Pharma Mar Sa Pegyleret liposomal doxorubicin i kombination med ecteinescidin 743
RS50510B (sr) 2004-10-29 2010-03-02 Pharma Mar S.A., Sociedad Unipersonal Formulacije koje sadrže ekteinascidin i disaharid
GB0522082D0 (en) * 2005-10-31 2005-12-07 Pharma Mar Sa Formulations
WO2009047752A1 (en) * 2007-10-09 2009-04-16 Ramot At Tel-Aviv University Ltd. Breast cancer therapy
US9486449B2 (en) 2007-10-09 2016-11-08 Malka COHEN-ARMON Cancer therapy
JP2011500046A (ja) * 2007-10-19 2011-01-06 ファルマ・マール・ソシエダード・アノニマ Et−743治療のための予後分子マーカー
US8871765B2 (en) 2010-07-27 2014-10-28 Cadila Healthcare Limited Substituted 4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one derivatives as poly (ADP-ribose) polymerase-1 inhibitors
ES2595240T3 (es) 2012-07-09 2016-12-28 Lupin Limited Derivados de tetrahidroquinazolinona como inhibidores de PARP
PL2938598T3 (pl) 2012-12-31 2017-05-31 Cadila Healthcare Limited Podstawione pochodne ftalazyn-1 (2H)-onu jako selektywne inhibitory polimerazy-1 poli(ADP-rybozy)
CN106853252B (zh) * 2015-12-09 2020-03-13 江苏恒瑞医药股份有限公司 曲贝替定药物组合物及其制备方法
CN108368059B (zh) * 2016-04-18 2022-02-01 深圳市塔吉瑞生物医药有限公司 一种取代的酞嗪酮化合物及其药物组合物
KR20180097876A (ko) * 2017-02-24 2018-09-03 주식회사 온코크로스 1,5-이소퀴놀린디올을 포함하는 피부 노화 방지 및 주름 개선용 조성물
HRP20231233T1 (hr) 2017-04-27 2024-01-19 Pharma Mar, S.A. Antitumorski spojevi
EP3960177A1 (en) * 2020-08-26 2022-03-02 Anturec Pharmaceuticals GmbH Composition comprising ttf-ngr for use in treating soft-tissue sarcoma

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635677B2 (en) * 1999-08-13 2003-10-21 Case Western Reserve University Methoxyamine combinations in the treatment of cancer
EP1365808B1 (en) * 2000-11-06 2011-01-19 Pharma Mar, S.A. Compositions for antitumour treatment containing ecteinascidin 743
WO2004105700A2 (en) * 2003-05-28 2004-12-09 Guildford Pharmaceuticals, Inc. Compounds, methods and pharmaceutical compositions for inhibiting parp
GB0317466D0 (en) * 2003-07-25 2003-08-27 Univ Sheffield Use
US20050187172A1 (en) * 2003-12-23 2005-08-25 Masferrer Jaime L. Combination of a Cox-2 inhibitor and a DNA topoisomerase I inhibitor for treatment of neoplasia
PE20060285A1 (es) * 2004-03-30 2006-05-08 Aventis Pharma Inc Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp)

Similar Documents

Publication Publication Date Title
JP2009517403A5 (https=)
US20160067241A1 (en) Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted naphthalimides such as amonafide for the treatment of immunological, metabolic, infectious, and benign or neoplastic hyperproliferative disease conditions
JP2009510171A5 (https=)
KR20160061911A (ko) 최적하 투여된 화학 화합물의 치료 효과
KR101292508B1 (ko) 백혈병의 치료를 위한, 피리미딜아미노벤즈아미드 화합물과 조합된 c-src 억제제의 용도
ES2361566T3 (es) Uso de inhibidores de parp-1.
JP2009511450A (ja) ニロチニブとファルネシルトランスフェラーゼ阻害剤の組合せ
TW201605450A (zh) Mdm2抑制劑與BRAF抑制劑之組合及其用途
US20130197017A1 (en) Combinations comprising a protein kinase inhibitor being a pyrimidylaminobenzamide compound and a hsp90 inhibitor such as 17-11g
US8653093B2 (en) Combination of pyrimidylaminobenzamide compounds and imatinib for treating or preventing proliferative diseases
JP2024528725A (ja) Parp阻害剤及びアシルフルベンの併用によるがんの治療
JP2008543771A (ja) アミノピリミジンキナーゼモジュレーターを用いたflt3キナーゼの相乗的モジュレーション
BRPI0612076A2 (pt) modulação sinergìstica de flt3 cinase empregando-se moduladores de aminopirimidinas cinase
EP2007391B1 (en) Combination comprising a) a pyrimidylaminobenzamide compound, and b) a thr315lle kinase inhibitor
JP2008501007A (ja) 異常な細胞増殖を治療するための方法
AU2011202833B2 (en) Combination comprising a) a pyrimidylaminobenzamide compound, and b) a Thr315lle kinase inhibitor