JP2009517390A5 - - Google Patents
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- Publication number
- JP2009517390A5 JP2009517390A5 JP2008542451A JP2008542451A JP2009517390A5 JP 2009517390 A5 JP2009517390 A5 JP 2009517390A5 JP 2008542451 A JP2008542451 A JP 2008542451A JP 2008542451 A JP2008542451 A JP 2008542451A JP 2009517390 A5 JP2009517390 A5 JP 2009517390A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- mapk
- inhibition
- compound
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 COc(cc1)ccc1N(C=C(*)C=C1)C1=O Chemical compound COc(cc1)ccc1N(C=C(*)C=C1)C1=O 0.000 description 2
- CVSLRGSGSRWNHX-UHFFFAOYSA-N O=C(C=Cc1c2)N(c3ccccc3)c1ccc2Br Chemical compound O=C(C=Cc1c2)N(c3ccccc3)c1ccc2Br CVSLRGSGSRWNHX-UHFFFAOYSA-N 0.000 description 1
- YWURBGXZPRESCI-UHFFFAOYSA-N Oc(cc1)ccc1N(C=C(C=C1)Br)C1=O Chemical compound Oc(cc1)ccc1N(C=C(C=C1)Br)C1=O YWURBGXZPRESCI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73931505P | 2005-11-23 | 2005-11-23 | |
| US77582306P | 2006-02-21 | 2006-02-21 | |
| US79352606P | 2006-04-20 | 2006-04-20 | |
| PCT/US2006/045287 WO2007062167A2 (en) | 2005-11-23 | 2006-11-22 | Method of modulating stress-activated protein kinase system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009517390A JP2009517390A (ja) | 2009-04-30 |
| JP2009517390A5 true JP2009517390A5 (https=) | 2009-11-26 |
Family
ID=38067929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542451A Withdrawn JP2009517390A (ja) | 2005-11-23 | 2006-11-22 | ストレス活性化プロテインキナーゼ系を調節する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110034495A1 (https=) |
| EP (2) | EP1960405A2 (https=) |
| JP (1) | JP2009517390A (https=) |
| KR (1) | KR20080076968A (https=) |
| AU (1) | AU2006318428A1 (https=) |
| BR (1) | BRPI0618939A2 (https=) |
| CA (1) | CA2630752A1 (https=) |
| WO (1) | WO2007062167A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2600460T3 (es) | 2005-05-10 | 2017-02-09 | Intermune, Inc. | Derivados de piridona-2-ona como moduladores del sistema de proteína cinasa activada por estrés |
| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| CN102099036B (zh) | 2008-06-03 | 2015-05-27 | 英特芒尼公司 | 用于治疗炎性疾患和纤维化疾患的化合物和方法 |
| US7635707B1 (en) | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
| SG176053A1 (en) * | 2009-05-15 | 2011-12-29 | Intermune Inc | Methods of treating hiv patients with anti-fibrotics |
| KR101478133B1 (ko) | 2009-05-25 | 2014-12-31 | 센트럴 사우스 유니버시티 | 1-（치환된 벤질기）-5-트리플루오로메틸-2-（1ｈ）피리돈 화합물 및 그 염의 제조방법 및 용도 |
| WO2010135972A1 (zh) | 2009-05-25 | 2010-12-02 | 中南大学 | 1-(取代芳基)-5-三氟甲基-2-（1h）吡啶酮化合物及其盐的制备方法及其用途 |
| GB0921730D0 (en) * | 2009-12-11 | 2010-01-27 | Respivert Ltd | Method of treatment |
| WO2012106382A1 (en) | 2011-01-31 | 2012-08-09 | Genoa Pharmaceuticals, Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| WO2014145485A2 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of Columbia University In The City Of New York | Map kinase modulators and uses thereof |
| AU2015204558B2 (en) | 2014-01-10 | 2020-04-30 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| MX382781B (es) | 2014-04-02 | 2025-03-13 | Intermune Inc | Piridinonas anti-fibroticas. |
| JP7040774B2 (ja) * | 2016-03-01 | 2022-03-23 | マックォーリー・ユニバーシティ | 神経学的症状の治療のためのリン酸化ｔａｕ及びｐ３８ガンマの使用 |
| ES2935615T3 (es) | 2017-12-15 | 2023-03-08 | Union Therapeutics As | Azetidina dihidrotienopiridinas sustituidas y su uso como inhibidores de la fosfodiesterasa |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2239357T3 (es) * | 1996-06-10 | 2005-09-16 | MERCK & CO., INC. | Imidazoles sustituidos que tienen actividad inhibidora de citoquinas. |
| GB0124848D0 (en) * | 2001-10-16 | 2001-12-05 | Celltech R&D Ltd | Chemical compounds |
| GB0214268D0 (en) * | 2002-06-20 | 2002-07-31 | Celltech R&D Ltd | Chemical compounds |
| CA2528602A1 (en) * | 2003-06-20 | 2004-12-29 | Celltech R & D Limited | Thienopyridone derivatives as kinase inhibitors |
-
2006
- 2006-11-22 KR KR1020087015085A patent/KR20080076968A/ko not_active Ceased
- 2006-11-22 EP EP06844534A patent/EP1960405A2/en not_active Withdrawn
- 2006-11-22 WO PCT/US2006/045287 patent/WO2007062167A2/en not_active Ceased
- 2006-11-22 JP JP2008542451A patent/JP2009517390A/ja not_active Withdrawn
- 2006-11-22 US US12/094,230 patent/US20110034495A1/en not_active Abandoned
- 2006-11-22 CA CA002630752A patent/CA2630752A1/en not_active Abandoned
- 2006-11-22 EP EP11006568A patent/EP2426134A3/en not_active Withdrawn
- 2006-11-22 AU AU2006318428A patent/AU2006318428A1/en not_active Abandoned
- 2006-11-22 BR BRPI0618939-3A patent/BRPI0618939A2/pt not_active IP Right Cessation
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