JP2009514963A5 - - Google Patents
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- Publication number
- JP2009514963A5 JP2009514963A5 JP2008540128A JP2008540128A JP2009514963A5 JP 2009514963 A5 JP2009514963 A5 JP 2009514963A5 JP 2008540128 A JP2008540128 A JP 2008540128A JP 2008540128 A JP2008540128 A JP 2008540128A JP 2009514963 A5 JP2009514963 A5 JP 2009514963A5
- Authority
- JP
- Japan
- Prior art keywords
- rosacea
- pharmaceutical composition
- granulomatous
- azithromycin
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000004700 rosacea Diseases 0.000 claims description 13
- 241001303601 Rosacea Species 0.000 claims description 11
- MQTOSJVFKKJCRP-BICOPXKESA-N Azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims description 5
- 229960004099 azithromycin Drugs 0.000 claims description 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 229920000742 Cotton Polymers 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 description 2
- 230000001225 therapeutic Effects 0.000 description 2
- 206010000496 Acne Diseases 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 206010025135 Lupus erythematosus Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 229940079593 drugs Drugs 0.000 description 1
- 230000000699 topical Effects 0.000 description 1
Description
肉芽腫性酒さは、治療するのが困難な疾患であることが判明している。酒さの他の様々なサブタイプに効果的であるほとんどの治療は、肉芽腫性酒さの治療には効果がない。肉芽腫性酒さに有効な治療がかなり必要とされている。
この出願の発明に関連する先行技術文献情報としては、以下のものがある（国際出願日以降国際段階で引用された文献及び他国に国内移行した際に引用された文献を含む）。
米国特許出願公開第２００２／０１８３３９９号明細書
ＦＥＲＮＡＮＤＥＺ−ＯＢＲＥＧＯＮ，Ａ．，Ｏｒａｌ ｕｓｅ ｏｆ ａｚｉｔｈｒｏｍｙｃｉｎ ｆｏｒ ｔｈｅ ｔｒｅａｔｍｅｎｔ ｏｆ ａｃｎｅ ｒｏｓａｃｅａ， Ａｒｃｈ Ｄｅｒｍａｔｏｌ，１４０：４８９−４９０（２００４）
ＢＡＫＡＲ，Ｏ．ｅｔ ａｌ，Ｐｈａｒｍａｃｏｌｏｇｙ ａｎｄ ｔｈｅｒａｐｅｕｔｉｃｓ：Ｔｈｅｒａｐｅｕｔｉｃ ｐｏｔｅｎｔｉａｌ ｏｆ ａｚｉｔｈｒｏｍｙｃｉｎ ｉｎ ｒｏｓａｃｅａ，Ｉｎｔ．Ｊ．Ｄｅｒｍａｔｏｌｏｇｙ，４３（２）：１５１（２００４）（Ａｂｓｔｒａｃｔ ｏｎｌｙ）
ＭｃＨＵＧＨ，ＲＣ ｅｔ ａｌ，Ａ ｔｏｐｉｃａｌ ａｚｉｔｈｒｏｍｙｃｉｎ ｐｒｅｐａｒａｔｉｏｎ ｆｏｒ ｔｈｅ ｔｒｅａｔｍｅｎｔ ｏｆ ａｃｎｅ ｖｕｌｇａｒｉｓ ａｎｄ ｒｏｓａｃｅａ，Ｊ．Ｄｅｒｍａｔｏｌｏｇｉｃ Ｔｒｅａｔｍｅｎｔ，１５（５）：２９５（２００４）
ＷＩＬＫＩＮ，Ｊ ｅｔ ａｌ，Ｓｔａｎｄａｒｄ ｃｌａｓｓｉｆｉｃａｔｉｏｎ ｏｆ ｒｏｓａｃｅａ：Ｒｅｐｏｒｔ ｏｆ ｔｈｅ Ｎａｔｉｏｎａｌ Ｒｏｓａｃｅａ Ｓｏｃｉｅｔｙ Ｅｘｐｅｒｔ Ｃｏｍｍｉｔｔｅｅ ｏｎ ｔｈｅ．．．，Ｊ．Ａｍ．Ａｃａｄ．Ｄｅｒｍａｔｏｌ．，４６：５８４−５８７（２００２）
ＫＨＯＫＨＡＲ，Ｏ ａｎｄ ＫＨＡＣＨＥＭＯＵＮＥ，Ａ，Ａ ｃａｓｅ ｏｆ ｇｒａｎｕｌｏｍａｔｏｕｓ ｒｏｓａｃｅａ：Ｓｏｒｔｉｎｇ ｇｒａｎｕｌｏｍａｔｏｕｓ ｒｏｓａｃｅａ ｆｒｏｍ ｏｔｈｅｒ ｇｒａｎｕｌｏｍａｔｏｕｓ．．．，Ｄｅｒｍａｔｏｌｏｇｙ Ｏｎｌｉｎｅ Ｊｏｕｒｎａｌ，１０（１）：６（２００４）
ＫＡＵＲ，Ｓ ｅｔ ａｌ，Ｇｒａｎｕｌｏｍａｔｏｕｓ ｒｏｓａｃｅａ：ｉｓ ｉｔ ａ ｖａｒｉａｎｔ ｏｆ ｌｕｐｕｓ ｍｉｌｉａｒｉｓ ｄｉｓｓｅｍｉｎａｔｕｓ ｆａｃｉｅｉ？，Ｉｎｄｉａｎ Ｊｏｕｒｎａｌ ｏｆ Ｄｅｒｍａｔｏｌｏｇｙ，Ｖｅｎｅｒｅｏｌｏｇｙ ａｎｄ Ｌｅｐｒｏｌｏｇｙ，６９（７）：５８−６０（２００３）
ＰＯＷＥＬＬ，ＦＣ，Ｒｏｓａｃｅａ，Ｎｅｗ Ｅｎｇｌａｎｄ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎｅ，３５２：７９３−８０３（Ｆｅｂｒｕａｒｙ ２００５）
ＫＵＰＩＥＣ−ＢＡＮＡＳＩＫＯＷＳＫＡ，Ａ，Ｒｏｓａｃｅａ，ｅＭｅｄｉｃｉｎｅ，ｕｐｄａｔｅｄ Ａｕｇｕｓｔ ２５，２００５
この出願の発明に関連する先行技術文献情報としては、以下のものがある（国際出願日以降国際段階で引用された文献及び他国に国内移行した際に引用された文献を含む）。
Claims (4)
- 肉芽腫性酒さの全身性治療に有効な量のアジスロマイシンを含む薬学的組成物。
- 請求項１記載の薬学的組成物において、この薬学的組成物は、少なくとも２週間にわたり、毎日又は一日おきに投与されるものである。
- 請求項１または２記載の薬学的組成物において、前記アジスロマイシンの用量は、１００〜１０００ｍｇ／回である。
- 請求項１〜３のいずれか１つに記載の薬学的組成物において、この薬学的組成物は、経口投与のための錠剤またはカプセルの形態である。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73484305P | 2005-11-09 | 2005-11-09 | |
| PCT/US2006/043339 WO2007086978A2 (en) | 2005-11-09 | 2006-11-08 | Azithromycin for treatment of granulomatous rosacea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009514963A JP2009514963A (ja) | 2009-04-09 |
| JP2009514963A5 true JP2009514963A5 (ja) | 2009-11-19 |
Family
ID=38309684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008540128A Pending JP2009514963A (ja) | 2005-11-09 | 2006-11-08 | 肉芽腫性酒さの治療ためのアジスロマイシン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070105788A1 (ja) |
| EP (1) | EP1945227A4 (ja) |
| JP (1) | JP2009514963A (ja) |
| CN (1) | CN101304750A (ja) |
| AU (1) | AU2006336612A1 (ja) |
| BR (1) | BRPI0617693A2 (ja) |
| CA (1) | CA2626551A1 (ja) |
| RU (1) | RU2008122964A (ja) |
| WO (1) | WO2007086978A2 (ja) |
| ZA (1) | ZA200804896B (ja) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8124123B2 (en) * | 2007-09-05 | 2012-02-28 | Dow Pharmaceutical Sciences, Inc. | Controlled release azithromycin solid dosages forms |
| US8143227B2 (en) * | 2007-09-05 | 2012-03-27 | Dow Pharmaceutical Sciences, Inc. | Azithromycin for treatment of skin disorders |
| JP5547096B2 (ja) * | 2008-02-28 | 2014-07-09 | アール．ピー． シェーラー テクノロジーズ エルエルシー | 多型を最小化する方法 |
| MX2011000247A (es) * | 2008-07-10 | 2011-03-30 | Inspire Pharmaceuticals Inc | Composicion farmaceutica para el tratamiento de blefaritis. |
| US20100190734A1 (en) * | 2009-01-23 | 2010-07-29 | Romulus Kimbro Brazzell | Method of treating dry eye disease with azithromycin |
| WO2012092378A1 (en) * | 2010-12-29 | 2012-07-05 | Inspire Pharmaceuticals, Inc. | Method for treating blepharitis |
| CN107823123A (zh) | 2011-06-28 | 2018-03-23 | 化学研究有限公司 | 高剂量粘膜粘附甲硝唑水基凝胶制剂及其治疗细菌性阴道病的用途 |
| US20140206735A1 (en) * | 2012-12-20 | 2014-07-24 | Medicis Pharmaceutical Corporation | High dosage topical metronidazole aqueous-based gel formulations and their use to treat rosacea |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002089743A2 (en) * | 2001-05-09 | 2002-11-14 | The Regents Of The University Of Michigan | Use of compositions for treating rosacea |
-
2006
- 2006-11-08 CA CA002626551A patent/CA2626551A1/en not_active Abandoned
- 2006-11-08 US US11/594,451 patent/US20070105788A1/en not_active Abandoned
- 2006-11-08 AU AU2006336612A patent/AU2006336612A1/en not_active Abandoned
- 2006-11-08 CN CNA2006800418105A patent/CN101304750A/zh active Pending
- 2006-11-08 BR BRPI0617693-3A patent/BRPI0617693A2/pt not_active IP Right Cessation
- 2006-11-08 WO PCT/US2006/043339 patent/WO2007086978A2/en active Application Filing
- 2006-11-08 EP EP06849873A patent/EP1945227A4/en not_active Withdrawn
- 2006-11-08 JP JP2008540128A patent/JP2009514963A/ja active Pending
- 2006-11-08 RU RU2008122964/14A patent/RU2008122964A/ru not_active Application Discontinuation
-
2008
- 2008-06-05 ZA ZA200804896A patent/ZA200804896B/xx unknown
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