JP2009514889A - 癌を治療するためにsaha及びボルテゾミブを用いる方法 - Google Patents
癌を治療するためにsaha及びボルテゾミブを用いる方法 Download PDFInfo
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- JP2009514889A JP2009514889A JP2008539097A JP2008539097A JP2009514889A JP 2009514889 A JP2009514889 A JP 2009514889A JP 2008539097 A JP2008539097 A JP 2008539097A JP 2008539097 A JP2008539097 A JP 2008539097A JP 2009514889 A JP2009514889 A JP 2009514889A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Otolaryngology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73395105P | 2005-11-04 | 2005-11-04 | |
| PCT/US2006/043112 WO2007056232A2 (en) | 2005-11-04 | 2006-11-03 | Methods of using saha and bortezomib for treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2009514889A true JP2009514889A (ja) | 2009-04-09 |
Family
ID=38023582
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008539097A Pending JP2009514889A (ja) | 2005-11-04 | 2006-11-03 | 癌を治療するためにsaha及びボルテゾミブを用いる方法 |
| JP2008539056A Pending JP2009514874A (ja) | 2005-11-04 | 2006-11-03 | Saha及びペメトレキセドを用いて癌を治療する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008539056A Pending JP2009514874A (ja) | 2005-11-04 | 2006-11-03 | Saha及びペメトレキセドを用いて癌を治療する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US20070197473A1 (OSRAM) |
| EP (2) | EP1954284A4 (OSRAM) |
| JP (2) | JP2009514889A (OSRAM) |
| CN (3) | CN101365440A (OSRAM) |
| AU (2) | AU2006311808A1 (OSRAM) |
| CA (2) | CA2636596A1 (OSRAM) |
| WO (2) | WO2007056232A2 (OSRAM) |
Families Citing this family (45)
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| EP2266552A3 (en) * | 2002-03-04 | 2011-03-02 | Merck HDAC Research, LLC | Methods of inducing terminal differentiation |
| WO2005070020A2 (en) * | 2004-01-23 | 2005-08-04 | The Regents Of The University Of Colorado | Gefitinib sensitivity-related gene expression and products and methods related thereto |
| US20080113874A1 (en) * | 2004-01-23 | 2008-05-15 | The Regents Of The University Of Colorado | Gefitinib sensitivity-related gene expression and products and methods related thereto |
| WO2005117553A2 (en) * | 2004-05-27 | 2005-12-15 | The Regents Of The University Of Colorado | Methods for prediction of clinical outcome to epidermal growth factor receptor inhibitors by cancer patients |
| ES2534302T3 (es) | 2004-11-12 | 2015-04-21 | Asuragen, Inc. | Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN |
| KR20150008926A (ko) * | 2005-03-11 | 2015-01-23 | 더 리전츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코퍼레이트 | 암 세포를 표피 성장 인자 억제제에 대해 감작화시키는 히스톤 데아세틸라제 억제제 |
| TWI365068B (en) | 2005-05-20 | 2012-06-01 | Merck Sharp & Dohme | Formulations of suberoylanilide hydroxamic acid and methods for producing same |
| US20070197473A1 (en) * | 2005-11-04 | 2007-08-23 | Frankel Stanley R | Methods of using SAHA and Bortezomib for treating cancer |
| CN101300015A (zh) * | 2005-11-04 | 2008-11-05 | 默克公司 | 使用n-辛二酰苯胺异羟肟酸和厄洛替尼治疗癌症的方法 |
| US8828392B2 (en) | 2005-11-10 | 2014-09-09 | Topotarget Uk Limited | Histone deacetylase (HDAC) inhibitors (PXD101) for the treatment of cancer alone or in combination with chemotherapeutic agent |
| US20080085874A1 (en) * | 2006-08-28 | 2008-04-10 | The Regents Of The University Of California | Small molecule potentiator of hormonal therapy for breast cancer |
| CN101528037A (zh) * | 2006-11-03 | 2009-09-09 | 默克公司 | 使用saha和硼替佐米治疗多发性骨髓瘤的方法 |
| EP2099443A4 (en) * | 2006-11-10 | 2010-05-05 | Syndax Pharmaceuticals Inc | ASSOCIATION OF ERA + LIGANDS AND HISTONE DEACETYLASE INHIBITORS IN THE TREATMENT OF CANCER |
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| WO2009015203A1 (en) * | 2007-07-23 | 2009-01-29 | Syndax Pharmaceuticals, Inc. | Novel compounds and methods of using them |
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| EP2622076A1 (en) * | 2010-09-30 | 2013-08-07 | University of Zürich | Treatment of b-cell lymphoma with microrna |
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| KR102040034B1 (ko) | 2017-12-13 | 2019-11-05 | 주식회사 아이큐어비앤피 | 페메트렉시드를 포함하는 경구용 약학 조성물 및 이의 제조방법 |
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| CN116585216A (zh) * | 2022-05-16 | 2023-08-15 | 上海中翊日化有限公司 | 一种含有羟基频哪酮视黄酸酯(hpr)并降低光损伤及炎症的抗衰组合物 |
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| WO2005018578A2 (en) * | 2003-08-26 | 2005-03-03 | Aton Pharma, Inc. | Method of treating cancer with hdac inhibitors |
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- 2006-11-03 WO PCT/US2006/043112 patent/WO2007056232A2/en not_active Ceased
- 2006-11-03 CN CNA2006800462589A patent/CN101325955A/zh active Pending
- 2006-11-03 WO PCT/US2006/042950 patent/WO2007056135A1/en not_active Ceased
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2008
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| WO2005018578A2 (en) * | 2003-08-26 | 2005-03-03 | Aton Pharma, Inc. | Method of treating cancer with hdac inhibitors |
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| US20080269182A1 (en) | 2008-10-30 |
| AU2006311808A1 (en) | 2007-05-18 |
| CA2627129A1 (en) | 2007-05-18 |
| CN101299921A (zh) | 2008-11-05 |
| US20090247549A1 (en) | 2009-10-01 |
| WO2007056232A2 (en) | 2007-05-18 |
| WO2007056232B1 (en) | 2007-11-08 |
| WO2007056135A1 (en) | 2007-05-18 |
| CA2636596A1 (en) | 2007-05-18 |
| WO2007056232A3 (en) | 2007-09-27 |
| CN101365440A (zh) | 2009-02-11 |
| EP1954284A4 (en) | 2010-01-06 |
| CN101325955A (zh) | 2008-12-17 |
| JP2009514874A (ja) | 2009-04-09 |
| US20070117815A1 (en) | 2007-05-24 |
| EP1954284A1 (en) | 2008-08-13 |
| AU2006311894A1 (en) | 2007-05-18 |
| US20070197473A1 (en) | 2007-08-23 |
| EP1947936A2 (en) | 2008-07-30 |
| EP1947936A4 (en) | 2010-02-10 |
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