JP2009513710A5 - - Google Patents
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- Publication number
- JP2009513710A5 JP2009513710A5 JP2008538978A JP2008538978A JP2009513710A5 JP 2009513710 A5 JP2009513710 A5 JP 2009513710A5 JP 2008538978 A JP2008538978 A JP 2008538978A JP 2008538978 A JP2008538978 A JP 2008538978A JP 2009513710 A5 JP2009513710 A5 JP 2009513710A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- hydroxy
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims 7
- NGEWQZIDQIYUNV-BYPYZUCNSA-N (S)-2-hydroxy-3-methylbutyric acid Chemical compound CC(C)[C@H](O)C(O)=O NGEWQZIDQIYUNV-BYPYZUCNSA-N 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000006239 protecting group Chemical group 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000002062 proliferating effect Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- NMHMNPHRMNGLLB-UHFFFAOYSA-N phloretic acid Chemical compound OC(=O)CCC1=CC=C(O)C=C1 NMHMNPHRMNGLLB-UHFFFAOYSA-N 0.000 claims 1
- 230000002194 synthesizing effect Effects 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 0 CC(C)[C@](*)C(N[C@@](Cc1ccc(*C(C23C(OC(C(C(*)N)N4)=CC5)=C5C(*5)=NC=C5c5c[n]6)Sc7c2cccc7-c2c5c6ccc2)c3c1)C4=O)=* Chemical compound CC(C)[C@](*)C(N[C@@](Cc1ccc(*C(C23C(OC(C(C(*)N)N4)=CC5)=C5C(*5)=NC=C5c5c[n]6)Sc7c2cccc7-c2c5c6ccc2)c3c1)C4=O)=* 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/264,502 US7517895B2 (en) | 2001-08-24 | 2005-10-31 | Synthetic diazonamides |
| US81465106P | 2006-06-16 | 2006-06-16 | |
| PCT/US2006/042565 WO2007053650A2 (en) | 2005-10-31 | 2006-10-31 | Diazonamide a analog |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009513710A JP2009513710A (ja) | 2009-04-02 |
| JP2009513710A5 true JP2009513710A5 (enExample) | 2009-11-26 |
Family
ID=38006479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008538978A Withdrawn JP2009513710A (ja) | 2005-10-31 | 2006-10-31 | ジアゾンアミドａ類似体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7538129B2 (enExample) |
| EP (1) | EP1948169A4 (enExample) |
| JP (1) | JP2009513710A (enExample) |
| AU (1) | AU2006308849A1 (enExample) |
| BR (1) | BRPI0618136A2 (enExample) |
| CR (1) | CR10038A (enExample) |
| EA (1) | EA013692B1 (enExample) |
| WO (1) | WO2007053650A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7851620B2 (en) * | 2007-06-07 | 2010-12-14 | Board Of Regents, The University Of Texas System | Methods for preparing diazonamides |
| US7960420B2 (en) * | 2007-12-21 | 2011-06-14 | Joyant Pharmaceuticals, Inc | Diazonamide analogs with improved solubility |
| EP2268146B1 (en) * | 2008-04-29 | 2015-08-26 | Joyant Pharmaceuticals, Inc. | Indoline anti-cancer agents |
| US8153619B2 (en) * | 2008-05-22 | 2012-04-10 | Joyant Pharmaceuticals, Inc. | Diazonamide analogs |
| HUE037730T2 (hu) * | 2011-04-22 | 2018-09-28 | Joyant Pharmaceuticals Inc | Diazonamid analógok |
| US10353032B2 (en) * | 2015-10-27 | 2019-07-16 | Halliburton Energy Services, Inc. | Viscosity determination apparatus, systems, and methods |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022720B2 (en) | 2001-08-24 | 2006-04-04 | Board Of Regents, The University Of Texas System | Synthetic diazonamides as novel anti-mitotic agents |
| US7517895B2 (en) * | 2001-08-24 | 2009-04-14 | Board Of Regents, The University Of Texas System | Synthetic diazonamides |
-
2006
- 2006-10-31 JP JP2008538978A patent/JP2009513710A/ja not_active Withdrawn
- 2006-10-31 WO PCT/US2006/042565 patent/WO2007053650A2/en not_active Ceased
- 2006-10-31 BR BRPI0618136-8A patent/BRPI0618136A2/pt not_active IP Right Cessation
- 2006-10-31 EA EA200801238A patent/EA013692B1/ru not_active IP Right Cessation
- 2006-10-31 EP EP06827230A patent/EP1948169A4/en not_active Withdrawn
- 2006-10-31 AU AU2006308849A patent/AU2006308849A1/en not_active Withdrawn
- 2006-10-31 US US11/591,016 patent/US7538129B2/en not_active Expired - Fee Related
-
2008
- 2008-05-30 CR CR10038A patent/CR10038A/es not_active Application Discontinuation
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