JP2009510046A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009510046A5 JP2009510046A5 JP2008532878A JP2008532878A JP2009510046A5 JP 2009510046 A5 JP2009510046 A5 JP 2009510046A5 JP 2008532878 A JP2008532878 A JP 2008532878A JP 2008532878 A JP2008532878 A JP 2008532878A JP 2009510046 A5 JP2009510046 A5 JP 2009510046A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- seen
- bands
- run
- gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000499 gel Substances 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 3
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 3
- 238000003556 assay Methods 0.000 description 2
- OWMVSZAMULFTJU-UHFFFAOYSA-N bis-tris Chemical compound OCCN(CCO)C(CO)(CO)CO OWMVSZAMULFTJU-UHFFFAOYSA-N 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 239000012146 running buffer Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72197405P | 2005-09-30 | 2005-09-30 | |
| GBGB0519923.7A GB0519923D0 (en) | 2005-09-30 | 2005-09-30 | Interleukin-13 antibody composition |
| PCT/GB2006/003650 WO2007036745A2 (en) | 2005-09-30 | 2006-09-29 | Interleukin-13 antibody composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013212846A Division JP5820450B2 (ja) | 2005-09-30 | 2013-10-10 | インターロイキン−13抗体組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009510046A JP2009510046A (ja) | 2009-03-12 |
| JP2009510046A5 true JP2009510046A5 (enExample) | 2009-07-09 |
Family
ID=37434894
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008532878A Pending JP2009510046A (ja) | 2005-09-30 | 2006-09-29 | インターロイキン−13抗体組成物 |
| JP2013212846A Active JP5820450B2 (ja) | 2005-09-30 | 2013-10-10 | インターロイキン−13抗体組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013212846A Active JP5820450B2 (ja) | 2005-09-30 | 2013-10-10 | インターロイキン−13抗体組成物 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US20080248048A1 (enExample) |
| EP (1) | EP1942939B2 (enExample) |
| JP (2) | JP2009510046A (enExample) |
| KR (1) | KR101363777B1 (enExample) |
| AU (1) | AU2006296399B2 (enExample) |
| BE (1) | BE2021C552I2 (enExample) |
| BR (1) | BRPI0616359B8 (enExample) |
| CA (1) | CA2623429C (enExample) |
| CY (2) | CY1120874T1 (enExample) |
| FI (1) | FIC20210042I1 (enExample) |
| FR (1) | FR21C1055I2 (enExample) |
| GB (1) | GB2430883B (enExample) |
| HU (1) | HUS2100053I1 (enExample) |
| IL (3) | IL189983A (enExample) |
| LT (1) | LTC1942939I2 (enExample) |
| LU (1) | LUC00239I2 (enExample) |
| NL (1) | NL301143I2 (enExample) |
| NO (2) | NO344859B1 (enExample) |
| PL (1) | PL1942939T5 (enExample) |
| SI (1) | SI1942939T2 (enExample) |
| WO (1) | WO2007036745A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8420086B2 (en) * | 2002-12-13 | 2013-04-16 | Immunomedics, Inc. | Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases |
| DK2805728T3 (da) | 2003-12-23 | 2020-04-20 | Genentech Inc | Hidtil ukendte anti-IL13-antistoffer og anvendelser deraf |
| MY144906A (en) | 2005-10-21 | 2011-11-30 | Novartis Ag | Human antibodies against il13 and therapeutic uses |
| MX2008012896A (es) | 2006-04-05 | 2008-10-14 | Abbott Biotech Ltd | Purificacion de anticuerpos. |
| EP2114451A2 (en) * | 2007-01-09 | 2009-11-11 | Wyeth a Corporation of the State of Delaware | Anti-il-13 antibody formulations and uses thereof |
| WO2009002521A2 (en) * | 2007-06-25 | 2008-12-31 | Amgen Inc. | Compositions of specific binding agents to hepatocyte growth factor |
| UA107557C2 (xx) * | 2007-07-06 | 2015-01-26 | Композиція антитіла офатумумабу | |
| WO2009009406A1 (en) * | 2007-07-06 | 2009-01-15 | Smithkline Beecham Corporation | Antibody formulations |
| EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| RU2607569C2 (ru) | 2008-03-31 | 2017-01-10 | Дженентек, Инк. | Композиции и способы для лечения и диагностики астмы |
| GB0904214D0 (en) | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| EP3037104B1 (en) | 2009-10-20 | 2020-05-27 | AbbVie Inc. | Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography |
| JP6005657B2 (ja) | 2010-12-16 | 2016-10-12 | ジェネンテック, インコーポレイテッド | Th2阻害に関連する診断及び治療 |
| TWI719112B (zh) | 2011-03-16 | 2021-02-21 | 賽諾菲公司 | 雙重v區類抗體蛋白質之用途 |
| BR112013025845A2 (pt) * | 2011-04-07 | 2018-09-04 | Glaxosmithkline Llc | formulações com viscosidade reduzida |
| AU2012283039A1 (en) * | 2011-07-13 | 2014-01-30 | Abbvie Inc. | Methods and compositions for treating asthma using anti-IL-13 antibodies |
| LT3091029T (lt) | 2011-10-31 | 2023-02-27 | F. Hoffmann-La Roche Ag | Anti-il13 antikūno kompozicijos |
| CN104334744A (zh) | 2012-03-27 | 2015-02-04 | 弗·哈夫曼-拉罗切有限公司 | 预测、诊断和治疗特发性肺纤维化的方法 |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| US10023608B1 (en) | 2013-03-13 | 2018-07-17 | Amgen Inc. | Protein purification methods to remove impurities |
| SG10201802525QA (en) | 2013-09-13 | 2018-04-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| KR102332302B1 (ko) | 2013-09-13 | 2021-12-01 | 제넨테크, 인크. | 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법 |
| BR112016008694A2 (pt) | 2013-10-23 | 2017-10-03 | Genentech Inc | Métodos de previsão da reação de pacientes com asma, de previsão da capacidade de reação de pacientes com asma, de identificação de pacientes com asma, de tratamento de pacientes portadores de asma e de tratamento de asma, uso de um kit e kit |
| JP2014062100A (ja) * | 2013-11-05 | 2014-04-10 | Glaxosmithkline Llc | 抗体処方 |
| CN106029693A (zh) | 2014-02-21 | 2016-10-12 | 豪夫迈·罗氏有限公司 | 抗il-13/il-17双特异性抗体及其用途 |
| CN106030304B (zh) * | 2014-02-27 | 2018-02-06 | 得克萨斯大学体系董事会 | 用于分离外来体的方法和组合物 |
| WO2015155710A1 (en) | 2014-04-11 | 2015-10-15 | Novartis Ag | Methods of selectively treating asthma using il-13 antagonists |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| JP6247241B2 (ja) * | 2015-02-27 | 2017-12-13 | ノバルティス アーゲー | 抗体処方 |
| CA2977285A1 (en) | 2015-03-16 | 2016-09-22 | F. Hoffmann-La Roche Ag | Methods of detecting and quantifying il-13 and uses in diagnosing and treating th2-associated diseases |
| WO2017139290A1 (en) * | 2016-02-10 | 2017-08-17 | Medimmune, Llc | Tralokinumab delivery device |
| EA037960B1 (ru) | 2016-04-27 | 2021-06-15 | Эббви Инк. | Способ лечения эозинофильного эзофагита с применением антитела против il-13 |
| CA3031589C (en) | 2016-09-23 | 2025-05-06 | Genentech, Inc. | USES OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS |
| AU2018263868A1 (en) | 2017-05-02 | 2019-12-12 | Merck Sharp & Dohme Llc | Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| EP3749362A1 (en) | 2018-02-09 | 2020-12-16 | F. Hoffmann-La Roche AG | Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases |
| JP7467438B2 (ja) | 2018-10-18 | 2024-04-15 | メルク・シャープ・アンド・ドーム・エルエルシー | 抗rsv抗体の製剤及びその使用方法 |
| CN113015748B (zh) | 2018-10-31 | 2025-12-12 | 默沙东有限责任公司 | 抗人pd-1抗体晶体及其使用方法 |
| WO2020092015A1 (en) | 2018-11-02 | 2020-05-07 | University Of Rochester | Therapeutic mitigation of epithelial infection |
| CN113316458B (zh) | 2018-11-07 | 2024-08-02 | 默沙东有限责任公司 | 抗lag3抗体和抗pd-1抗体的共制剂 |
| WO2021191220A1 (en) | 2020-03-23 | 2021-09-30 | Medimmune Limited | Methods for treating atopic dermatitis and related disorders |
| US12187788B2 (en) | 2020-03-23 | 2025-01-07 | Medimmune Limited | Methods for treating atopic dermatitis and related disorders |
| GB202108379D0 (en) | 2021-06-11 | 2021-07-28 | Medlmmune Ltd | Methods for treating a topic dermatitis and related disorders |
| WO2023023497A1 (en) | 2021-08-16 | 2023-02-23 | Medimmune Llc | Anti-il-13 antibody formulation |
| IL311027A (en) | 2021-09-15 | 2024-04-01 | Dermira Inc | Il-13 inhibitors for the treatment of prurigo nodularis |
| WO2023052408A1 (en) | 2021-09-28 | 2023-04-06 | Medimmune Limited | Methods for treating atopic dermatitis and related disorders |
| WO2025128984A1 (en) | 2023-12-14 | 2025-06-19 | Dermira, Inc. | Il-13 antibodies for the treatment of chronic rhinosinusitis with nasal polyps |
| TW202544035A (zh) | 2023-12-14 | 2025-11-16 | 美商德米拉股份有限公司 | 用於治療全年性過敏性鼻炎之il-13抗體 |
| WO2025184453A1 (en) | 2024-03-01 | 2025-09-04 | Dermira, Inc. | Il-13 antibodies for the treatment of post-inflammatory hyperpigmentation or hypopigmentation of skin |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217099B (hu) * | 1991-03-29 | 1999-11-29 | Elf Sanofi Sa. | Eljárás citokin típusú aktivitással rendelkező fehérje, azt kódoló rekombináns DNS-szekvencia és a megfelelő transzformált sejtek és mikroorganizmusok előállítására |
| FR2685919B1 (fr) * | 1992-01-08 | 1994-04-08 | Elf Sanofi | Proteine a activite de type cytokine, adn recombinant codant pour cette proteine, cellules animales transformees. |
| US5596072A (en) * | 1992-08-21 | 1997-01-21 | Schering Corporation | Method of refolding human IL-13 |
| JPH07267994A (ja) * | 1994-03-31 | 1995-10-17 | Snow Brand Milk Prod Co Ltd | 新規蛋白質及びその製造法 |
| JP3414856B2 (ja) * | 1994-08-09 | 2003-06-09 | 株式会社ヤトロン | ジフェニルエーテル化合物の免疫学的測定方法 |
| US5866154A (en) † | 1994-10-07 | 1999-02-02 | The Dupont Merck Pharmaceutical Company | Stabilized naloxone formulations |
| US6428788B1 (en) * | 1995-03-15 | 2002-08-06 | Penn State University | Compositions and methods for specifically targeting tumors |
| SK150298A3 (en) † | 1996-05-04 | 1999-04-13 | Zeneca Ltd | Monoclonal antibody to cea, conjugates comprising said antibody, and their therapeutic use in an adept system |
| GB9610992D0 (en) | 1996-05-24 | 1996-07-31 | Glaxo Group Ltd | Concentrated antibody preparation |
| US6991790B1 (en) * | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
| DK0999853T3 (da) | 1997-06-13 | 2003-04-22 | Genentech Inc | Stabiliseret antostofformulering |
| ES2229784T3 (es) † | 1998-06-09 | 2005-04-16 | Statens Serum Institut | Proceso de produccion de inmunoglobulinas para administracion intravenosa y otros productos de inmunoglobulina. |
| JP3537331B2 (ja) * | 1998-11-17 | 2004-06-14 | 積水化学工業株式会社 | Iv型コラーゲンの免疫測定法及び試薬 |
| BRPI0108923B8 (pt) † | 2000-03-03 | 2021-05-25 | Cambridge Antibody Tech Limited | elemento de ligação específico, ácido nucleico isolado, célula hospedeira, métodos para produzir um elemento de ligação específico ou domínio vh ou vl de anticorpo, e, para obter um elemento de ligação específico que liga eotaxina |
| EP1175931A1 (en) † | 2000-07-25 | 2002-01-30 | Computer Cell Culture Center S.A. | Integration of high cell density bioreactor operation with ultra fast on-line downstream processing |
| AU2002355285A1 (en) † | 2001-07-23 | 2003-02-17 | Accurate Polymers, Inc. | High-speed, solid-liquid separation |
| EP1578912A4 (en) * | 2001-10-26 | 2007-12-26 | Centocor Inc | IL-13 MUTEIN PROTEINS, ANTIBODIES, COMPOSITIONS, METHODS AND USES |
| US20040248260A1 (en) | 2001-10-26 | 2004-12-09 | Heavner George A. | IL-13 mutein proteins, antibodies, compositions, methods and uses |
| US20040234499A1 (en) * | 2001-10-26 | 2004-11-25 | David Shealy | Asthma-related anti-IL-13 immunoglobulin derived proteins, compositions, methods and uses |
| AU2003223497A1 (en) | 2002-04-05 | 2003-10-27 | Centocor, Inc. | Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses |
| CA2490423A1 (en) * | 2002-06-21 | 2003-12-31 | Biogen Idec Inc. | Buffered formulations for concentrating antibodies and methods of use thereof |
| EP1601697B1 (en) † | 2003-02-28 | 2007-05-30 | Lonza Biologics plc | Antibody purification by Protein A and ion exchange chromatography |
| EP1614693A4 (en) † | 2003-03-31 | 2006-07-19 | Kirin Brewery | Purification of a human monoclonal antibody and human polyclonal antibody |
| HRP20050934B1 (hr) * | 2003-04-04 | 2014-09-26 | Genentech, Inc. | Formulacije s visokom koncentracijom antitijela i proteina |
| GB0407315D0 (en) * | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| TW200530269A (en) * | 2003-12-12 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Anti-Mpl antibodies |
| DK2805728T3 (da) † | 2003-12-23 | 2020-04-20 | Genentech Inc | Hidtil ukendte anti-IL13-antistoffer og anvendelser deraf |
| CN1234725C (zh) † | 2004-04-07 | 2006-01-04 | 陈志南 | 一种高效快速纯化制备片段抗体的方法 |
| AR049390A1 (es) † | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
| EP1793856A2 (en) * | 2004-08-20 | 2007-06-13 | Amgen Inc. | Methods and compositions for treating allergic inflammation |
| WO2006055638A2 (en) * | 2004-11-17 | 2006-05-26 | Abgenix, Inc. | Fully human monoclonal antibodies to il-13 |
| US20060171943A1 (en) * | 2005-02-01 | 2006-08-03 | Amgen Inc. | Compositions and methods of treating fibrotic disorders |
| BR112013009173A2 (pt) † | 2010-10-14 | 2016-07-26 | Ticona Gmbh | polioximetileno plastificante |
-
2006
- 2006-09-29 WO PCT/GB2006/003650 patent/WO2007036745A2/en not_active Ceased
- 2006-09-29 KR KR1020087010374A patent/KR101363777B1/ko active Active
- 2006-09-29 GB GB0619204A patent/GB2430883B/en active Active
- 2006-09-29 BR BRPI0616359A patent/BRPI0616359B8/pt active IP Right Grant
- 2006-09-29 US US12/067,120 patent/US20080248048A1/en not_active Abandoned
- 2006-09-29 PL PL06794604T patent/PL1942939T5/pl unknown
- 2006-09-29 AU AU2006296399A patent/AU2006296399B2/en active Active
- 2006-09-29 CA CA2623429A patent/CA2623429C/en not_active Expired - Fee Related
- 2006-09-29 SI SI200632277T patent/SI1942939T2/sl unknown
- 2006-09-29 JP JP2008532878A patent/JP2009510046A/ja active Pending
- 2006-09-29 EP EP06794604.6A patent/EP1942939B2/en active Active
-
2008
- 2008-03-06 IL IL189983A patent/IL189983A/en active IP Right Grant
- 2008-04-23 NO NO20081946A patent/NO344859B1/no active Protection Beyond IP Right Term
-
2010
- 2010-12-13 US US12/966,377 patent/US9107945B2/en active Active
-
2013
- 2013-10-10 JP JP2013212846A patent/JP5820450B2/ja active Active
- 2013-12-17 IL IL230005A patent/IL230005A/en active IP Right Grant
-
2015
- 2015-07-14 US US14/798,685 patent/US10358488B2/en active Active
-
2016
- 2016-07-10 IL IL246674A patent/IL246674B/en active IP Right Grant
-
2018
- 2018-07-20 CY CY181100758T patent/CY1120874T1/el unknown
-
2021
- 2021-11-03 NL NL301143C patent/NL301143I2/nl unknown
- 2021-11-05 CY CY2021033C patent/CY2021033I1/el unknown
- 2021-11-09 LU LU00239C patent/LUC00239I2/fr unknown
- 2021-11-12 NO NO2021050C patent/NO2021050I1/no unknown
- 2021-11-16 FR FR21C1055C patent/FR21C1055I2/fr active Active
- 2021-11-17 LT LTPA2021528C patent/LTC1942939I2/lt unknown
- 2021-11-22 BE BE2021C552C patent/BE2021C552I2/nl unknown
- 2021-11-23 FI FIC20210042C patent/FIC20210042I1/fi unknown
- 2021-12-02 HU HUS2100053C patent/HUS2100053I1/hu unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009510046A5 (enExample) | ||
| EA201491599A1 (ru) | Антитела к матриксной металлопротеиназе 9 | |
| BR112021020023A2 (pt) | Ligantes de conjugação melhorados | |
| WO2017085172A3 (en) | Improved serum albumin binders | |
| CL2013000951A1 (es) | Anticuerpo que presenta alta afinidad con proteinas tau solubles e insoluble y modula los niveles tau solubles e insolubles; peptido de union; composicion farmaceutica que comprende el peptido o proteina de union, un anticuerpo o polinucleotido; uso para tratar enfermedad neurodegenerativa. | |
| WO2017197014A3 (en) | Compositions comprising a polymeric dye and a cyclodextrin and uses thereof | |
| EA201390146A1 (ru) | Антитела к матриксной металлопротеиназе 9 | |
| WO2015073884A3 (en) | Glycoengineered antibody compositions | |
| EA200801918A1 (ru) | Агрохимические препараты | |
| CU20180024A7 (es) | Moléculas de unión a linfopoyetina estromal tímica (tslp), composiciones farmacéuticas que las contienen y método de producción de las mismas | |
| WO2014059442A8 (en) | Antibody based reagents that specifically recognize toxic oligomeric forms of tau | |
| TR201909218T4 (tr) | Pestisit işlevine sahip moleküller ve bunlarla ilişkili aramaddeler, bileşimler ve işlemler. | |
| BR112013030163A2 (pt) | composto, uso cosmético de pelo menos um composto, composição farmacêutica ou cosmética e processo para preparar um composto. | |
| NO347649B1 (no) | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. | |
| BR112015001841A2 (pt) | filete ou listra de segurança, processo para fazer o mesmo ,substrato de segurança, processo para fazer o mesmo , uso do filete ou listra de segurança e documento de segurança. | |
| EA201690731A1 (ru) | Анализ igfbp7, имеющий улучшенную характеристику в биологических образцах | |
| WO2015006337A3 (en) | Compositions and methods for increasing protein half-life in a serum | |
| PH12014501931A1 (en) | Antibodies to matrix metalloproteinase 9 | |
| WO2015075269A9 (en) | Antibodies against ccr9 and applications thereof | |
| BR112014025707A2 (pt) | produto de condensação com base em monômero, processo para a preparação do mesmo, seu uso e composição compreendendo o mesmo. | |
| EP4443155A3 (en) | Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis | |
| MX2019012375A (es) | Formulaciones del inhibidor del antigeno-1 asociado a la funcion de linfocitos (lfa-1). | |
| WO2017153329A3 (en) | A particulate earth alkali carbonate-comprising material and/or particulate earth alkali phosphate-comprising material for nox uptake | |
| GB201014028D0 (en) | In-situ reagent | |
| EA200970597A1 (ru) | Новые бис(диалкиламиды), способ получения и применения |