JP2009510044A - ピラゾロ［３，４−ｂ］ピリジン化合物及びそのＰＤＥ４阻害薬としての使用 - Google Patents
ピラゾロ［３，４−ｂ］ピリジン化合物及びそのＰＤＥ４阻害薬としての使用 Download PDFInfo
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- JP2009510044A JP2009510044A JP2008532874A JP2008532874A JP2009510044A JP 2009510044 A JP2009510044 A JP 2009510044A JP 2008532874 A JP2008532874 A JP 2008532874A JP 2008532874 A JP2008532874 A JP 2008532874A JP 2009510044 A JP2009510044 A JP 2009510044A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
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- Health & Medical Sciences (AREA)
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| US72159705P | 2005-09-29 | 2005-09-29 | |
| PCT/GB2006/003627 WO2007036734A1 (en) | 2005-09-29 | 2006-09-29 | Pyrazolo[3,4-b]pyridine compound, and its use as a pde4 inhibitor |
Publications (2)
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| JP2009510044A true JP2009510044A (ja) | 2009-03-12 |
| JP2009510044A5 JP2009510044A5 (https=) | 2009-11-05 |
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| JP2008532873A Expired - Fee Related JP5323484B2 (ja) | 2005-09-29 | 2006-09-29 | ピラゾロ［３，４−ｂ］ピリジン化合物及びそのＰＤＥ４阻害薬としての使用 |
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| EP (2) | EP1940835B1 (https=) |
| JP (2) | JP2009510044A (https=) |
| AT (1) | ATE503756T1 (https=) |
| DE (1) | DE602006021044D1 (https=) |
| ES (1) | ES2363795T3 (https=) |
| WO (2) | WO2007036733A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013530131A (ja) * | 2010-04-20 | 2013-07-25 | エフ．ホフマン−ラ ロシュ アーゲー | ピラゾロピリジン誘導体 |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE503756T1 (de) * | 2005-09-29 | 2011-04-15 | Glaxo Group Ltd | Pyrazoloä3,4-büpyridinverbindungen und ihre verwendung als pde4-inhibitoren |
| GB0614570D0 (en) * | 2006-07-21 | 2006-08-30 | Glaxo Group Ltd | Compounds |
| SI2046787T1 (sl) | 2006-08-01 | 2011-07-29 | Glaxo Group Ltd | Pirazolo(3,4-b)piridinske spojine in njihova uporaba kot PDE4 inhibitorji |
| DK2124944T3 (da) * | 2007-03-14 | 2012-04-23 | Ranbaxy Lab Ltd | Pyrazolo[3,4-b]pyridinderivater som phosphodiesteraseinhibitorer |
| KR20100017297A (ko) | 2007-04-26 | 2010-02-16 | 다케다 야쿠힌 고교 가부시키가이샤 | ２환식 화합물 및 이의 약학적 용도 |
| WO2009100169A1 (en) * | 2008-02-06 | 2009-08-13 | Glaxo Group Limited | Dual pharmacophores - pde4-muscarinic antagonistics |
| EP2249830A4 (en) * | 2008-02-06 | 2012-07-18 | Glaxo Group Ltd | DUAL PHARMACOPHORES, ANTAGONISTS OF MUSCARINIC RECEPTORS AND INHIBITORS OF PDE4 ACTIVITY |
| JP2012502977A (ja) * | 2008-09-19 | 2012-02-02 | ランバクシー ラボラトリーズ リミテッド | ホスホジエステラーゼ阻害薬 |
| AU2010219097A1 (en) | 2009-01-13 | 2011-08-04 | Glaxo Group Limited | Pyrimidinecarboxamide derivatives as inhibitors of SYK kinase |
| WO2011113512A1 (de) * | 2010-03-16 | 2011-09-22 | Merck Patent Gmbh | Morpholinylchinazoline |
| US20140113898A1 (en) * | 2010-11-08 | 2014-04-24 | Zalicus Pharmaceuticals Ltd. | Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers |
| EP2574607A1 (en) * | 2011-09-06 | 2013-04-03 | F. Hoffmann-La Roche AG | PDE10 modulators |
| US9243001B2 (en) | 2013-03-15 | 2016-01-26 | Epizyme, Inc. | Substituted benzene compounds |
| CA2903572A1 (en) * | 2013-03-15 | 2014-10-23 | Epizyme, Inc. | Substituted benzene compounds |
| US9011934B2 (en) | 2013-06-14 | 2015-04-21 | SatisPharma, LLC | Multi-purpose anti-itch treatment |
| EP3102576B8 (en) | 2014-02-03 | 2019-06-19 | Vitae Pharmaceuticals, LLC | Dihydropyrrolopyridine inhibitors of ror-gamma |
| DE102014009164A1 (de) * | 2014-06-03 | 2015-12-03 | Herbalist & Doc Gesundheitsgesellschaft Mbh | Silikonölhaltige nasal anzuwendende Formulierungen |
| PT3207043T (pt) | 2014-10-14 | 2019-03-25 | Vitae Pharmaceuticals Llc | Inibidores de di-hidropirrolopiridina de ror-gama |
| US9452178B1 (en) | 2014-10-22 | 2016-09-27 | SatisPharma, LLC | Acne formulations, treatments, and pressure sensitive patches for delivery of acne formulations |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
| WO2017024018A1 (en) | 2015-08-05 | 2017-02-09 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
| US11008340B2 (en) | 2015-11-20 | 2021-05-18 | Vitae Pharmaceuticals, Llc | Modulators of ROR-gamma |
| TW202220968A (zh) | 2016-01-29 | 2022-06-01 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| CN110121498A (zh) | 2016-12-20 | 2019-08-13 | 先正达参股股份有限公司 | 具有杀线虫活性的n-环丁基-噻唑-5-甲酰胺 |
| AU2018238138A1 (en) | 2017-03-21 | 2019-10-17 | Arbutus Biopharma Corporation | Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same |
| JP2020528904A (ja) | 2017-07-24 | 2020-10-01 | ヴァイティー ファーマシューティカルズ，エルエルシー | ＲＯＲγの阻害剤 |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
| TW201920188A (zh) * | 2017-08-10 | 2019-06-01 | 美商美國禮來大藥廠 | [1,2,4]三唑衍生物 |
| US12582809B2 (en) | 2018-01-26 | 2026-03-24 | Bt Bidco, Inc. | Treatment of a disease of the gastrointestinal tract with a PDE4 inhibitor |
| US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| CA3168494A1 (en) * | 2020-01-23 | 2021-07-29 | Roopa Rai | Pgdh inhibitors and methods of making and using |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009510043A (ja) * | 2005-09-29 | 2009-03-12 | グラクソ グループ リミテッド | ピラゾロ［３，４−ｂ］ピリジン化合物及びそのＰＤＥ４阻害薬としての使用 |
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| CN100387598C (zh) * | 2002-09-16 | 2008-05-14 | 葛兰素集团有限公司 | 吡唑并[3,4-b]吡啶化合物及其作为磷酸二酯酶抑制剂的用途 |
| GB0230045D0 (en) * | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009510043A (ja) * | 2005-09-29 | 2009-03-12 | グラクソ グループ リミテッド | ピラゾロ［３，４−ｂ］ピリジン化合物及びそのＰＤＥ４阻害薬としての使用 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013530131A (ja) * | 2010-04-20 | 2013-07-25 | エフ．ホフマン−ラ ロシュ アーゲー | ピラゾロピリジン誘導体 |
Also Published As
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| US20090131431A1 (en) | 2009-05-21 |
| EP1940835A1 (en) | 2008-07-09 |
| DE602006021044D1 (de) | 2011-05-12 |
| JP2009510043A (ja) | 2009-03-12 |
| EP1940836A1 (en) | 2008-07-09 |
| EP1940835B1 (en) | 2011-03-30 |
| WO2007036734A1 (en) | 2007-04-05 |
| JP5323484B2 (ja) | 2013-10-23 |
| US20080255186A1 (en) | 2008-10-16 |
| ES2363795T3 (es) | 2011-08-16 |
| ATE503756T1 (de) | 2011-04-15 |
| WO2007036733A1 (en) | 2007-04-05 |
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