JP2009509692A - オピオイドアゴニスト及び/又はオピオイドアンタゴニストを用いる経皮薬剤送達システム、装置及び方法 - Google Patents

オピオイドアゴニスト及び/又はオピオイドアンタゴニストを用いる経皮薬剤送達システム、装置及び方法 Download PDF

Info

Publication number
JP2009509692A
JP2009509692A JP2008533767A JP2008533767A JP2009509692A JP 2009509692 A JP2009509692 A JP 2009509692A JP 2008533767 A JP2008533767 A JP 2008533767A JP 2008533767 A JP2008533767 A JP 2008533767A JP 2009509692 A JP2009509692 A JP 2009509692A
Authority
JP
Japan
Prior art keywords
opioid
opioid antagonist
electrode structure
subject
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008533767A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009509692A5 (enExample
Inventor
カーター,ダリック
Original Assignee
Tti・エルビュー株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tti・エルビュー株式会社 filed Critical Tti・エルビュー株式会社
Publication of JP2009509692A publication Critical patent/JP2009509692A/ja
Publication of JP2009509692A5 publication Critical patent/JP2009509692A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444Membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details
    • A61N1/306Arrangements where at least part of the apparatus is introduced into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36021External stimulators, e.g. with patch electrodes for treatment of pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
JP2008533767A 2005-09-30 2006-09-29 オピオイドアゴニスト及び/又はオピオイドアンタゴニストを用いる経皮薬剤送達システム、装置及び方法 Withdrawn JP2009509692A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72213605P 2005-09-30 2005-09-30
PCT/US2006/038549 WO2007041544A1 (en) 2005-09-30 2006-09-29 Transdermal drug delivery systems, devices, and methods employing opioid agonist and/or opioid antagonist

Publications (2)

Publication Number Publication Date
JP2009509692A true JP2009509692A (ja) 2009-03-12
JP2009509692A5 JP2009509692A5 (enExample) 2009-10-15

Family

ID=37696075

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008533767A Withdrawn JP2009509692A (ja) 2005-09-30 2006-09-29 オピオイドアゴニスト及び/又はオピオイドアンタゴニストを用いる経皮薬剤送達システム、装置及び方法

Country Status (10)

Country Link
EP (1) EP1931421A1 (enExample)
JP (1) JP2009509692A (enExample)
KR (1) KR20080058433A (enExample)
CN (2) CN101321554A (enExample)
AU (1) AU2006299521A1 (enExample)
BR (1) BRPI0616788A2 (enExample)
CA (1) CA2622684A1 (enExample)
IL (1) IL190245A0 (enExample)
RU (1) RU2008117168A (enExample)
WO (1) WO2007041544A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010110397A1 (ja) * 2009-03-25 2010-09-30 国立大学法人 香川大学 マイクロニードルおよびその製造方法と金型

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100239523A1 (en) * 2007-10-30 2010-09-23 The Regents Of The University Of Colorado Tlr modulators and methods for using the same
AU2009225434B2 (en) 2008-03-21 2014-05-22 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
EP2303016A4 (en) 2008-05-01 2011-11-30 Univ California METHOD AND USE FOR THE USE OF SELECTIVE DELTA OPIOID RECEPTOR 1 AGONISTS, DELTA OPIOID RECEPTOR 2 AGONISTS AND / OR MU OPIOID RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ACTIVE SUBSTANCES
CA2841785A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 薬剤送達方法及びシステム
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
CN106730311B (zh) * 2016-12-27 2019-10-29 潍坊大地医疗器械有限公司 经络综合治疗仪电极触头装置
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 経皮薬剤送達の装置及び方法
GB201704909D0 (en) 2017-03-28 2017-05-10 Ldn Pharma Ltd Cancer therapy
WO2019090125A2 (en) * 2017-11-02 2019-05-09 Chrono Therapeutics Inc. Smart abuse-deterrent transdermal drug delivery system
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
ES3011582T3 (en) 2019-02-21 2025-04-07 Pharmaceutical Productions Inc Naloxone formulations for sublingual and/or buccal administration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4879297A (en) * 1987-06-01 1989-11-07 Warner-Lambert Company Fatty acids and their small chain esters as penetration enhancers in aqueous systems
US5312326A (en) * 1992-06-02 1994-05-17 Alza Corporation Iontophoretic drug delivery apparatus
EA009921B1 (ru) * 2003-07-25 2008-04-28 Еуро-Селтик С.А. Способ лечения синдрома отвыкания от зависимости у беременных женщин
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010110397A1 (ja) * 2009-03-25 2010-09-30 国立大学法人 香川大学 マイクロニードルおよびその製造方法と金型
JP2010247535A (ja) * 2009-03-25 2010-11-04 Kagawa Univ マイクロニードルおよびその製造方法と金型

Also Published As

Publication number Publication date
AU2006299521A1 (en) 2007-04-12
BRPI0616788A2 (pt) 2011-07-05
WO2007041544A1 (en) 2007-04-12
CN101321554A (zh) 2008-12-10
CA2622684A1 (en) 2007-04-12
KR20080058433A (ko) 2008-06-25
CN101316623A (zh) 2008-12-03
RU2008117168A (ru) 2009-11-10
EP1931421A1 (en) 2008-06-18
IL190245A0 (en) 2008-11-03

Similar Documents

Publication Publication Date Title
US7848801B2 (en) Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
JP2009509658A (ja) ヒドロゲルを用いる経皮薬剤送達システム、装置及び方法
US20070093789A1 (en) Iontophoresis apparatus and method for delivery of angiogenic factors to enhance healing of injured tissue
US20070093788A1 (en) Iontophoresis method and apparatus for systemic delivery of active agents
US20070083186A1 (en) Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles
US20070093787A1 (en) Iontophoresis device to deliver multiple active agents to biological interfaces
US20080058701A1 (en) Delivery device having self-assembling dendritic polymers and method of use thereof
US20080033398A1 (en) Device and method for enhancing immune response by electrical stimulation
JP2009509692A (ja) オピオイドアゴニスト及び/又はオピオイドアンタゴニストを用いる経皮薬剤送達システム、装置及び方法
JP2009509657A (ja) 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
US20070081944A1 (en) Iontophoresis apparatus and method for the diagnosis of tuberculosis
EP0813879B1 (en) Drug administration composition for iontophoresis
MX2008004223A (en) Transdermal drug delivery systems, devices, andmethods employing opioid agonist and/or opioid antagonist
HK1125876A (en) Transdermal drug delivery systems, devices, and methods employing opioid agonist and/or opioid antagonist
MX2008004224A (es) Metodo y aparato de iontoforesis para el suministro sistemico de agentes activos
HK1125875A (en) Iontophoresis method and apparatus for systemic delivery of active agents

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090831

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090831

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20100125