JP2009508965A5 - - Google Patents
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- Publication number
- JP2009508965A5 JP2009508965A5 JP2008532389A JP2008532389A JP2009508965A5 JP 2009508965 A5 JP2009508965 A5 JP 2009508965A5 JP 2008532389 A JP2008532389 A JP 2008532389A JP 2008532389 A JP2008532389 A JP 2008532389A JP 2009508965 A5 JP2009508965 A5 JP 2009508965A5
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- JP
- Japan
- Prior art keywords
- compound
- therapeutic composition
- composition according
- activity
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 239000000203 mixture Substances 0.000 claims 41
- 230000001225 therapeutic effect Effects 0.000 claims 34
- 150000001875 compounds Chemical class 0.000 claims 27
- 230000000694 effects Effects 0.000 claims 8
- 241000124008 Mammalia Species 0.000 claims 5
- 230000000241 respiratory effect Effects 0.000 claims 5
- -1 S-nitrosothiol compound Chemical class 0.000 claims 4
- 230000033764 rhythmic process Effects 0.000 claims 3
- 238000009423 ventilation Methods 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 150000003431 steroids Chemical class 0.000 claims 2
- ICRHORQIUXBEPA-UHFFFAOYSA-N thionitrous acid Chemical compound SN=O ICRHORQIUXBEPA-UHFFFAOYSA-N 0.000 claims 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 claims 1
- 229940124125 5 Lipoxygenase inhibitor Drugs 0.000 claims 1
- 229940122072 Carbonic anhydrase inhibitor Drugs 0.000 claims 1
- 206010010904 Convulsion Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 239000000867 Lipoxygenase Inhibitor Substances 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 229940065524 anticholinergics inhalants for obstructive airway diseases Drugs 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 239000003420 antiserotonin agent Substances 0.000 claims 1
- 230000037007 arousal Effects 0.000 claims 1
- 210000000133 brain stem Anatomy 0.000 claims 1
- 229940124630 bronchodilator Drugs 0.000 claims 1
- 239000000168 bronchodilator agent Substances 0.000 claims 1
- 239000003489 carbonate dehydratase inhibitor Substances 0.000 claims 1
- 239000000812 cholinergic antagonist Substances 0.000 claims 1
- 229940111134 coxibs Drugs 0.000 claims 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 claims 1
- 229960003638 dopamine Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000003193 general anesthetic agent Substances 0.000 claims 1
- 229940005494 general anesthetics Drugs 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 claims 1
- 230000004199 lung function Effects 0.000 claims 1
- 239000003887 narcotic antagonist Substances 0.000 claims 1
- 229960002748 norepinephrine Drugs 0.000 claims 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 claims 1
- 239000000014 opioid analgesic Substances 0.000 claims 1
- 229940005483 opioid analgesics Drugs 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 239000003169 respiratory stimulant agent Substances 0.000 claims 1
- 230000004799 sedative–hypnotic effect Effects 0.000 claims 1
- 239000000952 serotonin receptor agonist Substances 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 claims 1
- 229940127228 tetracyclic antidepressant Drugs 0.000 claims 1
- 230000003519 ventilatory effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71877205P | 2005-09-20 | 2005-09-20 | |
| PCT/US2006/036846 WO2007035879A2 (en) | 2005-09-20 | 2006-09-20 | Combination s-nitrosothiol-based pharmaceutical products for restoring normal breathing rhythm |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009508965A JP2009508965A (ja) | 2009-03-05 |
| JP2009508965A5 true JP2009508965A5 (enExample) | 2009-11-26 |
Family
ID=37889538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008532389A Withdrawn JP2009508965A (ja) | 2005-09-20 | 2006-09-20 | 正常な呼吸リズムを回復するための組み合わせｓ−ニトロソチオールをベースとする製薬学的製品 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100035998A1 (enExample) |
| EP (1) | EP1940369A4 (enExample) |
| JP (1) | JP2009508965A (enExample) |
| KR (1) | KR20080059229A (enExample) |
| CN (1) | CN101291660A (enExample) |
| AU (1) | AU2006292154A1 (enExample) |
| BR (1) | BRPI0616144A2 (enExample) |
| CA (1) | CA2623184A1 (enExample) |
| WO (1) | WO2007035879A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7073501B2 (en) * | 1999-02-04 | 2006-07-11 | Univerity Technologies International Inc. | Ventilatory stabilization technology |
| US20090025725A1 (en) * | 2007-07-26 | 2009-01-29 | Uti Limited Partnership | Transient intervention for modifying the breathing of a patient |
| CN101888870B (zh) * | 2007-10-26 | 2013-11-27 | 优特埃合伙有限公司 | 换气稳定系统 |
| WO2009151744A1 (en) * | 2008-04-02 | 2009-12-17 | Galleon Pharmaceuticals, Inc. | S-nitrosomercapto compounds and related derivatives |
| DE102010030096A1 (de) | 2010-06-15 | 2011-12-15 | Wacker Chemie Ag | Silanvernetzende Zusammensetzungen |
| US20120101073A1 (en) * | 2010-10-22 | 2012-04-26 | Galleon Pharmaceutical, Inc. | Novel Method For Treating Breathing Disorders or Diseases |
| WO2025207125A1 (en) * | 2024-03-26 | 2025-10-02 | The Regents Of The University Of California | Combination pharmacological interventions for obstructive sleep apnea |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5380758A (en) * | 1991-03-29 | 1995-01-10 | Brigham And Women's Hospital | S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof |
| ZA963590B (en) * | 1995-05-10 | 1996-11-19 | Adcock Ingram Ltd | Pharmaceutical composition |
| JP2003523958A (ja) * | 1999-12-23 | 2003-08-12 | ニトロメド インコーポレーテッド | ニトロソ化およびニトロシル化されたシクロオキシゲナーゼ−２の阻害剤、組成物ならびに使用法 |
| US20020183366A1 (en) * | 2001-03-23 | 2002-12-05 | Garvey David S. | Cyclooxygenase-2 inhibitors, compositions and methods of use |
| CA2459647A1 (en) * | 2001-08-20 | 2003-02-27 | University Of Virginia Patent Foundation | Use of s-nitrosothiol signaling to treat disordered control of breathing |
-
2006
- 2006-09-20 KR KR1020087009277A patent/KR20080059229A/ko not_active Withdrawn
- 2006-09-20 WO PCT/US2006/036846 patent/WO2007035879A2/en not_active Ceased
- 2006-09-20 US US11/992,074 patent/US20100035998A1/en not_active Abandoned
- 2006-09-20 CA CA002623184A patent/CA2623184A1/en not_active Abandoned
- 2006-09-20 AU AU2006292154A patent/AU2006292154A1/en not_active Abandoned
- 2006-09-20 CN CNA200680038514XA patent/CN101291660A/zh active Pending
- 2006-09-20 BR BRPI0616144-8A patent/BRPI0616144A2/pt not_active IP Right Cessation
- 2006-09-20 EP EP06815112A patent/EP1940369A4/en not_active Withdrawn
- 2006-09-20 JP JP2008532389A patent/JP2009508965A/ja not_active Withdrawn
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