JP2009504792A5 - - Google Patents

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Publication number
JP2009504792A5
JP2009504792A5 JP2008527371A JP2008527371A JP2009504792A5 JP 2009504792 A5 JP2009504792 A5 JP 2009504792A5 JP 2008527371 A JP2008527371 A JP 2008527371A JP 2008527371 A JP2008527371 A JP 2008527371A JP 2009504792 A5 JP2009504792 A5 JP 2009504792A5
Authority
JP
Japan
Prior art keywords
formula
compound
phenyl
azabicyclo
trifluoromethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2008527371A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009504792A (ja
Filing date
Publication date
Priority claimed from GBGB0517191.3A external-priority patent/GB0517191D0/en
Application filed filed Critical
Publication of JP2009504792A publication Critical patent/JP2009504792A/ja
Publication of JP2009504792A5 publication Critical patent/JP2009504792A5/ja
Ceased legal-status Critical Current

Links

JP2008527371A 2005-08-22 2006-08-18 化合物 Ceased JP2009504792A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0517191.3A GB0517191D0 (en) 2005-08-22 2005-08-22 Compounds
PCT/EP2006/008201 WO2007022934A2 (en) 2005-08-22 2006-08-18 Azabicyclo (3, 1, 0) hexan derivatives useful as modulators of dopamine d3 receptors

Publications (2)

Publication Number Publication Date
JP2009504792A JP2009504792A (ja) 2009-02-05
JP2009504792A5 true JP2009504792A5 (cg-RX-API-DMAC7.html) 2009-10-01

Family

ID=35098097

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008527371A Ceased JP2009504792A (ja) 2005-08-22 2006-08-18 化合物

Country Status (8)

Country Link
US (1) US7745458B2 (cg-RX-API-DMAC7.html)
EP (1) EP1926723B1 (cg-RX-API-DMAC7.html)
JP (1) JP2009504792A (cg-RX-API-DMAC7.html)
AT (1) ATE431345T1 (cg-RX-API-DMAC7.html)
DE (1) DE602006006850D1 (cg-RX-API-DMAC7.html)
ES (1) ES2327162T3 (cg-RX-API-DMAC7.html)
GB (1) GB0517191D0 (cg-RX-API-DMAC7.html)
WO (1) WO2007022934A2 (cg-RX-API-DMAC7.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101143718B1 (ko) * 2004-02-23 2012-07-05 글락소 그룹 리미티드 도파민 ｄ3 수용체의 조절제로서 유용한 아자비시클로(3.1.0) 헥산 유도체
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンｄ３受容体のモジュレーターとしてのアザビシクロ［３．１．０］ヘキサン誘導体
WO2007016155A2 (en) 2005-07-27 2007-02-08 Dov Pharmaceutical, Inc. Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
ATE487715T1 (de) * 2005-08-22 2010-11-15 Glaxo Group Ltd Triazolderivate als modulatoren von dopamin-d3- rezeptoren
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
EP2010518B1 (en) * 2006-04-03 2011-02-16 Glaxo Group Limited Azabicyclo [3. 1. o] hexane derivatives as modulators of dopamine d3 receptors
WO2007113260A1 (en) * 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
US7727988B2 (en) * 2006-04-03 2010-06-01 Glaxo Group Limited Azabicyclo[3.1.0]hex-3-yl}alkyl)pyrimidinedione
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
GB0719234D0 (en) * 2007-10-02 2007-11-14 Glaxo Group Ltd Novel compounds
GB0719235D0 (en) * 2007-10-02 2007-11-14 Glaxo Group Ltd Novel compounds
EP2445887B1 (en) 2009-06-26 2014-11-05 Panacea Biotec Limited Novel azabicyclohexanes
US8957254B2 (en) 2009-07-06 2015-02-17 Solvay Sa Process for chemical synthesis from an alkenone made from a halogenated precursor
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
JP6183053B2 (ja) * 2012-08-22 2017-08-23 宇部興産株式会社 テトラヒドロピラニルピリミジン化合物の製造方法
WO2019146740A1 (ja) 2018-01-26 2019-08-01 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する環式化合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
AU2303402A (en) 2000-11-14 2002-05-27 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
EA006708B1 (ru) * 2001-10-22 2006-02-24 Пфайзер Продактс Инк. Производные 3-азабицикло (3.1.0) гексана в качестве антагонистов опиоидного рецептора
KR101143718B1 (ko) * 2004-02-23 2012-07-05 글락소 그룹 리미티드 도파민 ｄ3 수용체의 조절제로서 유용한 아자비시클로(3.1.0) 헥산 유도체
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンｄ３受容体のモジュレーターとしてのアザビシクロ［３．１．０］ヘキサン誘導体
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
GB0517175D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
ATE487715T1 (de) 2005-08-22 2010-11-15 Glaxo Group Ltd Triazolderivate als modulatoren von dopamin-d3- rezeptoren
US7727988B2 (en) 2006-04-03 2010-06-01 Glaxo Group Limited Azabicyclo[3.1.0]hex-3-yl}alkyl)pyrimidinedione
GB0616574D0 (en) 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

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