JP2009108098A5 - - Google Patents
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- Publication number
- JP2009108098A5 JP2009108098A5 JP2008335693A JP2008335693A JP2009108098A5 JP 2009108098 A5 JP2009108098 A5 JP 2009108098A5 JP 2008335693 A JP2008335693 A JP 2008335693A JP 2008335693 A JP2008335693 A JP 2008335693A JP 2009108098 A5 JP2009108098 A5 JP 2009108098A5
- Authority
- JP
- Japan
- Prior art keywords
- labeled
- dye
- energy transfer
- substituted
- nucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 *CC1OC(BI*)C(*)C1* Chemical compound *CC1OC(BI*)C(*)C1* 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/724,855 US6583168B1 (en) | 1997-11-25 | 2000-11-28 | Sulfonated diarylrhodamine dyes |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002546764A Division JP4486781B2 (ja) | 2000-11-28 | 2001-11-27 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010161112A Division JP2010285625A (ja) | 2000-11-28 | 2010-07-15 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009108098A JP2009108098A (ja) | 2009-05-21 |
| JP2009108098A5 true JP2009108098A5 (https=) | 2010-11-25 |
Family
ID=24912198
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002546764A Expired - Fee Related JP4486781B2 (ja) | 2000-11-28 | 2001-11-27 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
| JP2008335693A Withdrawn JP2009108098A (ja) | 2000-11-28 | 2008-12-29 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
| JP2009272932A Withdrawn JP2010053137A (ja) | 2000-11-28 | 2009-11-30 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
| JP2010161112A Pending JP2010285625A (ja) | 2000-11-28 | 2010-07-15 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002546764A Expired - Fee Related JP4486781B2 (ja) | 2000-11-28 | 2001-11-27 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009272932A Withdrawn JP2010053137A (ja) | 2000-11-28 | 2009-11-30 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
| JP2010161112A Pending JP2010285625A (ja) | 2000-11-28 | 2010-07-15 | 蛍光標識としてのスルホン化ジアリールローダミン色素 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6583168B1 (https=) |
| EP (3) | EP2179996A1 (https=) |
| JP (4) | JP4486781B2 (https=) |
| AU (1) | AU2002219896A1 (https=) |
| CA (1) | CA2429816A1 (https=) |
| WO (1) | WO2002044416A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5936087A (en) * | 1997-11-25 | 1999-08-10 | The Perkin-Elmer Corporation | Dibenzorhodamine dyes |
| CA2375060A1 (en) * | 1999-05-24 | 2000-11-30 | Life Technologies Corporation | Method for deblocking of labeled oligonucleotides |
| US6979530B2 (en) * | 2001-05-21 | 2005-12-27 | Applera Corporation | Peptide conjugates and fluorescence detection methods for intracellular caspase assay |
| WO2004003510A2 (en) * | 2002-07-01 | 2004-01-08 | Guava Technologies, Inc. | Fluorescent dyes, energy transfer couples and methods |
| US20050186606A1 (en) * | 2004-02-11 | 2005-08-25 | Schroeder Benjamin G. | Methods and compositions for detecting nucleic acids |
| EP1781675B1 (en) | 2004-08-13 | 2014-03-26 | Epoch Biosciences, Inc. | Phosphonate fluorescent dyes and conjugates |
| US7767834B2 (en) * | 2004-08-13 | 2010-08-03 | Elitech Holding B.V. | Phosphonylated fluorescent dyes and conjugates |
| CN101258220A (zh) * | 2004-09-16 | 2008-09-03 | 阿普里拉股份有限公司 | 荧光染料化合物,共轭物及其应用 |
| CN101454315B (zh) * | 2006-03-31 | 2016-08-17 | 应用生物系统有限责任公司 | 用于合成罗丹明-标记的寡核苷酸的试剂 |
| US8178360B2 (en) * | 2006-05-18 | 2012-05-15 | Illumina Cambridge Limited | Dye compounds and the use of their labelled conjugates |
| GB0611405D0 (en) | 2006-06-09 | 2006-07-19 | Univ Belfast | FKBP-L: A novel inhibitor of angiogenesis |
| KR101117722B1 (ko) * | 2009-08-28 | 2012-03-07 | 삼성모바일디스플레이주식회사 | 유기 발광 소자 |
| KR101193182B1 (ko) | 2009-09-02 | 2012-10-19 | 삼성디스플레이 주식회사 | 유기 발광 소자 |
| DE102010042634A1 (de) * | 2010-10-19 | 2012-04-19 | Atto-Tec Gmbh | Neue Amin-substituierte tricyclische Fluoreszenzfarbstoffe |
| WO2013078244A1 (en) | 2011-11-21 | 2013-05-30 | Promega Corporation | Carboxy x rhodamine analogs |
| JP5729491B2 (ja) * | 2012-01-24 | 2015-06-03 | 株式会社島津製作所 | 有機系太陽電池用色素材料の分析方法及び精製方法 |
| WO2014106957A1 (ja) * | 2013-01-07 | 2014-07-10 | 国立大学法人 東京大学 | 非対称Siローダミン及びロドールの合成 |
| JP6815603B2 (ja) * | 2016-11-22 | 2021-01-20 | スガイ化学工業株式会社 | ジナフトチオフェン誘導体及びその製造方法 |
| JP2018090536A (ja) * | 2016-12-02 | 2018-06-14 | 国立大学法人 東京大学 | 近赤外蛍光レシオ型プローブ |
| JP2018090535A (ja) * | 2016-12-02 | 2018-06-14 | 国立大学法人 東京大学 | 近赤外蛍光カルシウムプローブ |
| CN109111421B (zh) * | 2018-10-12 | 2022-04-22 | 湖南科技大学 | 一种氧杂蒽类荧光探针及其制备方法和应用 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230558A (en) | 1978-10-02 | 1980-10-28 | Coulter Electronics, Inc. | Single drop separator |
| JPS55141460A (en) * | 1979-04-20 | 1980-11-05 | Agency Of Ind Science & Technol | Preparation of sulfanilic acid and naphthionic acid |
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4973679A (en) | 1981-03-27 | 1990-11-27 | University Patents, Inc. | Process for oligonucleo tide synthesis using phosphormidite intermediates |
| US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
| US4855225A (en) | 1986-02-07 | 1989-08-08 | Applied Biosystems, Inc. | Method of detecting electrophoretically separated oligonucleotides |
| US4811218A (en) | 1986-06-02 | 1989-03-07 | Applied Biosystems, Inc. | Real time scanning electrophoresis apparatus for DNA sequencing |
| US5151507A (en) | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| JPS641949A (en) | 1987-06-24 | 1989-01-06 | Hitachi Ltd | Regeneration of electrophoretic gel |
| US5231191A (en) | 1987-12-24 | 1993-07-27 | Applied Biosystems, Inc. | Rhodamine phosphoramidite compounds |
| US5262530A (en) | 1988-12-21 | 1993-11-16 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
| US5047524A (en) | 1988-12-21 | 1991-09-10 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
| US5141813A (en) | 1989-08-28 | 1992-08-25 | Clontech Laboratories, Inc. | Multifunctional controlled pore glass reagent for solid phase oligonucleotide synthesis |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5274240A (en) | 1990-01-12 | 1993-12-28 | The Regents Of The University Of California | Capillary array confocal fluorescence scanner and method |
| US5091652A (en) | 1990-01-12 | 1992-02-25 | The Regents Of The University Of California | Laser excited confocal microscope fluorescence scanner and method |
| US5405975A (en) * | 1993-03-29 | 1995-04-11 | Molecular Probes, Inc. | Fluorescent ion-selective diaryldiaza crown ether conjugates |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| GB9024176D0 (en) * | 1990-11-07 | 1990-12-19 | Medical Res Council | Photolabile compounds,their synthesis and use as fluorophores |
| US5750409A (en) | 1991-11-18 | 1998-05-12 | Boehringer Mannheim Gmbh | Pentacyclic compounds and their use as absorption or fluorescent dyes |
| DE4137934A1 (de) | 1991-11-18 | 1993-05-19 | Boehringer Mannheim Gmbh | Neue pentacyklische verbindungen und ihre verwendung als absorptions- oder fluoreszenzfarbstoffe |
| ATE173767T1 (de) | 1992-04-03 | 1998-12-15 | Perkin Elmer Corp | Proben zusammensetzung und verfahren |
| DE69324494T2 (de) | 1992-09-03 | 1999-09-23 | The Perkin-Elmer Corp., Foster City | 4,7-dichlorofluoroszein-farbestoffe als molekulare sonden |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| AU1254295A (en) | 1993-12-17 | 1995-07-03 | Perkin-Elmer Corporation, The | Uncharged polymers for separation of biomolecules by capillary electrophoresis |
| US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| US5543026A (en) | 1994-02-07 | 1996-08-06 | The Perkin-Elmer Corporation | Real-time scanning fluorescence electrophoresis apparatus for the analysis of polynucleotide fragments |
| US5605809A (en) | 1994-10-28 | 1997-02-25 | Oncoimmunin, Inc. | Compositions for the detection of proteases in biological samples and methods of use thereof |
| US5912340A (en) | 1995-10-04 | 1999-06-15 | Epoch Pharmaceuticals, Inc. | Selective binding complementary oligonucleotides |
| US5736626A (en) | 1996-01-29 | 1998-04-07 | The Perkin-Elmer Corporation | Solid support reagents for the direct synthesis of 3'-labeled polynucleotides |
| US6020481A (en) * | 1996-04-01 | 2000-02-01 | The Perkin-Elmer Corporation | Asymmetric benzoxanthene dyes |
| US5945526A (en) | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5800996A (en) * | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US6080852A (en) * | 1996-06-27 | 2000-06-27 | The Perkin-Elmer Corporation | 4,7-dichlororhodamine dyes |
| US5821356A (en) | 1996-08-12 | 1998-10-13 | The Perkin Elmer Corporation | Propargylethoxyamino nucleotides |
| ES2192672T3 (es) | 1996-11-18 | 2003-10-16 | Takeshi Imanishi | Nuevos analogos de nucleotidos. |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US5770716A (en) | 1997-04-10 | 1998-06-23 | The Perkin-Elmer Corporation | Substituted propargylethoxyamido nucleosides, oligonucleotides and methods for using same |
| AU9063398A (en) | 1997-09-12 | 1999-04-05 | Exiqon A/S | Oligonucleotide analogues |
| US6130101A (en) | 1997-09-23 | 2000-10-10 | Molecular Probes, Inc. | Sulfonated xanthene derivatives |
| US6008379A (en) * | 1997-10-01 | 1999-12-28 | The Perkin-Elmer Corporation | Aromatic-substituted xanthene dyes |
| US5936087A (en) | 1997-11-25 | 1999-08-10 | The Perkin-Elmer Corporation | Dibenzorhodamine dyes |
| US6080868A (en) * | 1998-01-23 | 2000-06-27 | The Perkin-Elmer Corporation | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds |
| US6096875A (en) | 1998-05-29 | 2000-08-01 | The Perlein-Elmer Corporation | Nucleotide compounds including a rigid linker |
| US5948648A (en) | 1998-05-29 | 1999-09-07 | Khan; Shaheer H. | Nucleotide compounds including a rigid linker |
| DE60001531T2 (de) * | 1999-04-23 | 2003-10-02 | Molecular Probes, Inc. | Xanthenfarbstoffe und ihre anwendung als lumineszenzlöschende verbindungen |
| DE19923168A1 (de) * | 1999-05-20 | 2000-11-23 | Roche Diagnostics Gmbh | Neue Fluoreszenzfarbstoffe und ihre Verwendung als Fluoreszenzmarker |
| US6248884B1 (en) * | 1999-06-03 | 2001-06-19 | The Perkin-Elmer Corporation | Extended rhodamine compounds useful as fluorescent labels |
| AU1312502A (en) * | 2000-10-11 | 2002-04-22 | Pe Corp Ny | Fluorescent nucleobase conjugates having anionic linkers |
-
2000
- 2000-11-28 US US09/724,855 patent/US6583168B1/en not_active Expired - Lifetime
-
2001
- 2001-11-27 JP JP2002546764A patent/JP4486781B2/ja not_active Expired - Fee Related
- 2001-11-27 WO PCT/US2001/044475 patent/WO2002044416A2/en not_active Ceased
- 2001-11-27 EP EP09016135A patent/EP2179996A1/en not_active Withdrawn
- 2001-11-27 AU AU2002219896A patent/AU2002219896A1/en not_active Abandoned
- 2001-11-27 CA CA002429816A patent/CA2429816A1/en not_active Abandoned
- 2001-11-27 EP EP01998658A patent/EP1339798A2/en not_active Ceased
- 2001-11-27 EP EP09016130A patent/EP2221347A1/en not_active Withdrawn
-
2003
- 2003-06-24 US US10/602,974 patent/US7018431B2/en not_active Expired - Lifetime
-
2008
- 2008-12-29 JP JP2008335693A patent/JP2009108098A/ja not_active Withdrawn
-
2009
- 2009-11-30 JP JP2009272932A patent/JP2010053137A/ja not_active Withdrawn
-
2010
- 2010-07-15 JP JP2010161112A patent/JP2010285625A/ja active Pending
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