JP2008546760A5 - - Google Patents

Download PDF

Info

Publication number
JP2008546760A5
JP2008546760A5 JP2008517706A JP2008517706A JP2008546760A5 JP 2008546760 A5 JP2008546760 A5 JP 2008546760A5 JP 2008517706 A JP2008517706 A JP 2008517706A JP 2008517706 A JP2008517706 A JP 2008517706A JP 2008546760 A5 JP2008546760 A5 JP 2008546760A5
Authority
JP
Japan
Prior art keywords
pain
seq
use according
antibody
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008517706A
Other languages
English (en)
Japanese (ja)
Other versions
JP5419448B2 (ja
JP2008546760A (ja
Filing date
Publication date
Priority claimed from IT000332A external-priority patent/ITRM20050332A1/it
Application filed filed Critical
Publication of JP2008546760A publication Critical patent/JP2008546760A/ja
Publication of JP2008546760A5 publication Critical patent/JP2008546760A5/ja
Application granted granted Critical
Publication of JP5419448B2 publication Critical patent/JP5419448B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2008517706A 2005-06-24 2006-06-23 疼痛に対するオピオイド鎮痛薬効果の増強のための方法 Expired - Fee Related JP5419448B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM2005A000332 2005-06-24
IT000332A ITRM20050332A1 (it) 2005-06-24 2005-06-24 Uso di molecole in grado di bloccare l'attivita' di trka per potenziare gli effetti di analgesici oppiacei sul dolore.
PCT/IT2006/000488 WO2006137106A2 (en) 2005-06-24 2006-06-23 Method for the potentiation of opioid analgesics effects on pain

Publications (3)

Publication Number Publication Date
JP2008546760A JP2008546760A (ja) 2008-12-25
JP2008546760A5 true JP2008546760A5 (cg-RX-API-DMAC7.html) 2009-08-06
JP5419448B2 JP5419448B2 (ja) 2014-02-19

Family

ID=37514252

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008517706A Expired - Fee Related JP5419448B2 (ja) 2005-06-24 2006-06-23 疼痛に対するオピオイド鎮痛薬効果の増強のための方法

Country Status (10)

Country Link
US (2) US7988966B2 (cg-RX-API-DMAC7.html)
EP (1) EP1893649B1 (cg-RX-API-DMAC7.html)
JP (1) JP5419448B2 (cg-RX-API-DMAC7.html)
AU (1) AU2006260490B2 (cg-RX-API-DMAC7.html)
CA (1) CA2612941C (cg-RX-API-DMAC7.html)
DK (1) DK1893649T3 (cg-RX-API-DMAC7.html)
IL (1) IL188252A (cg-RX-API-DMAC7.html)
IT (1) ITRM20050332A1 (cg-RX-API-DMAC7.html)
WO (1) WO2006137106A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200709949B (cg-RX-API-DMAC7.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20030601A1 (it) 2003-12-24 2005-06-25 Lay Line Genomics Spa Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
ITRM20050290A1 (it) 2005-06-07 2006-12-08 Lay Line Genomics Spa Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
BRPI0822049B1 (pt) * 2007-12-17 2021-11-16 Pfizer Limited Composiqao farmaceutica compreendendo anticorpo antagonista anti-ngf, kit e uso de um anticorpo antingf
EP2252633B9 (en) * 2008-02-04 2014-02-19 Lay Line Genomics S.P.A. Anti-trka antibodies and derivatives thereof
EP2116539A1 (en) * 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
JP5752601B2 (ja) 2008-12-08 2015-07-22 ブイエム ファーマ エルエルシー タンパク質受容体チロシンキナーゼ阻害薬の組成物
SG175436A1 (en) 2009-05-04 2011-12-29 Abbott Res Bv Antibodies against nerve growth factor (ngf) with enhanced in vivo stability
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
EP2646468B1 (en) 2010-12-01 2018-07-25 AlderBio Holdings LLC Anti-ngf compositions and use thereof
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
EP2731439A4 (en) 2011-07-12 2014-12-03 Merck Sharp & Dohme TRKA KINASE INHIBITORS, COMPOSITIONS AND METHOD THEREFOR
US8926978B2 (en) 2011-10-25 2015-01-06 Anaptysbio, Inc. Antibodies directed against nerve growth factor (NGF)
WO2013176970A1 (en) 2012-05-22 2013-11-28 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
ES2666126T3 (es) * 2012-06-08 2018-05-03 Glenmark Pharmaceuticals S.A. Anticuerpos anti-TrkA humanizados con sustituciones de aminoácidos
EP2674439B1 (en) * 2012-06-13 2017-02-01 Rottapharm Biotech S.r.l. Anti-TrkA antibodies, derivatives and uses thereof
WO2015039333A1 (en) 2013-09-22 2015-03-26 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
WO2015039334A1 (en) 2013-09-22 2015-03-26 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
TN2016000228A1 (en) 2013-12-17 2017-10-06 Esteve Labor Dr SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) AND SIGMA RECEPTOR LIGANDS COMBINATIONS.
KR101723997B1 (ko) * 2014-02-05 2017-04-06 브이엠 온콜로지 엘엘씨 화합물의 조성물 및 이의 용도
WO2015143654A1 (en) 2014-03-26 2015-10-01 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
WO2015143653A1 (en) 2014-03-26 2015-10-01 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
WO2015143652A1 (en) 2014-03-26 2015-10-01 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
MA41097A (fr) * 2014-12-05 2017-10-10 Glenmark Pharmaceuticals Sa Anticorps anti-trka à propriétés inhibitrices améliorées et dérivés desdits anticorps destinés à être utilisés pour traiter les douleurs osseuses
WO2016161572A1 (en) 2015-04-08 2016-10-13 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
AR114110A1 (es) 2018-02-28 2020-07-22 Lilly Co Eli Anticuerpo anti-trka

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9525180D0 (en) * 1995-12-08 1996-02-07 Univ Mcgill Design of hormone-like antibodies with agonistic and antagonistic fuctions
IT1306704B1 (it) * 1999-05-26 2001-10-02 Sirs Societa Italiana Per La R Anticorpi monoclonali e suoi derivati sintetici o biotecnologici ingrado di agire come molecole antagoniste per il ngf.
UA80447C2 (en) * 2002-10-08 2007-09-25 Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
BRPI0407375A (pt) 2003-02-19 2006-02-07 Rinat Neuroscience Corp Métodos para tratar dor por meio da administração de um antagonista do fator de crescimento neural e u nsaid e composições contendo os mesmos
ITRM20030601A1 (it) * 2003-12-24 2005-06-25 Lay Line Genomics Spa Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
EP2252633B9 (en) 2008-02-04 2014-02-19 Lay Line Genomics S.P.A. Anti-trka antibodies and derivatives thereof

Similar Documents

Publication Publication Date Title
JP2008546760A5 (cg-RX-API-DMAC7.html)
IL262092B2 (en) Human anti-pacap antibodies and their use
JP2014516026A5 (cg-RX-API-DMAC7.html)
JP2008542439A5 (cg-RX-API-DMAC7.html)
JP2008542440A5 (cg-RX-API-DMAC7.html)
JP2020502271A5 (cg-RX-API-DMAC7.html)
JP2009505676A5 (cg-RX-API-DMAC7.html)
RU2019102009A (ru) Специфические антитела к pd-l1 и способы их применения
IL292193B2 (en) Anti-b7-h1 antibodies for treating tumors
NZ599405A (en) Targeted binding agents against b7-h1
JP2018070648A5 (cg-RX-API-DMAC7.html)
HRP20130922T1 (hr) U potpunosti humana protutijela protiv humanog 4-1bb (cd137)
NZ602892A (en) Antibodies that bind human cd27 and uses thereof
AR081434A1 (es) Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo
JP2012510461A5 (cg-RX-API-DMAC7.html)
JP2014502955A5 (cg-RX-API-DMAC7.html)
RU2014138039A (ru) Фармацевтическая композиция для лечения и/или профилактики рака
RU2014138040A (ru) Фармацевтическая композиция для лечения и/или профилактики рака
JP2017506217A5 (cg-RX-API-DMAC7.html)
RU2014138038A (ru) Фармацевтическая композиция для лечения профилактики рака
RU2017108173A (ru) Комбинированная терапия на основе антител, активирующих человеческий cd40, и антител к человеческому pd-l1
JP2016529215A5 (cg-RX-API-DMAC7.html)
HRP20150439T1 (hr) Protutijela za humani angiopoietin 2
RU2014143785A (ru) Фармацевтическая композиция для лечения и/или предотвращения рака печени
BR112014002613A2 (pt) anticorpo, composição farmacêutica, combinação farmacêutica para tratamento e/ou prevenção de câncer, dna e método